HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$684+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$684
(LATAM Airlines)

Popular in

July

Cheapest in

September

Average price

$567
From Charleston to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($278 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($82 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/294:14 pmCHS - SCL
1 stop14h 26mLATAM Airlines
mar. 11/411:10 pmSCL - CHS
1 stop20h 50mLATAM Airlines
Deal found 9/11$684
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/293:31 pmCHS - SCL
2 stops16h 24mAmerican Airlines
mar. 11/411:15 pmSCL - CHS
1 stop17h 16mAmerican Airlines
Deal found 9/9$688
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:55 pmCHS - SCL
3 stops31h 22mMultiple Airlines
sáb. 11/15:59 amSCL - CHS
3 stops29h 07mMultiple Airlines
Deal found 9/10$759
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/254:14 pmCHS - SCL
1 stop14h 26mLATAM Airlines
sáb. 11/111:10 pmSCL - CHS
1 stop13h 10mLATAM Airlines
Deal found 9/10$764
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/228:05 amCHS - SCL
2 stops19h 55mLATAM Airlines
dom. 11/3010:50 amSCL - CHS
2 stops15h 07mLATAM Airlines
Deal found 9/9$768
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/228:05 amCHS - SCL
1 stop21h 35mDelta
dom. 11/3011:10 pmSCL - CHS
1 stop25h 38mDelta
Deal found 9/9$769
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/252:50 pmCHS - SCL
1 stop15h 10mDelta
lun. 9/299:40 pmSCL - CHS
1 stop17h 05mDelta
Deal found 9/9$784
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/2510:10 amCHS - SCL
1 stop20h 45mAmerican Airlines
lun. 9/299:55 pmSCL - CHS
1 stop12h 44mAmerican Airlines
Deal found 9/8$1,064

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 10/29

12:54 pm-6:35 am

2 stops16h 41m

Santiago Arturo Merino Benitez

mar. 11/4

6:40 am-11:59 pm

2 stops19h 19m

$684

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 10/29

7:44 pm-8:55 am

1 stop12h 11m

Santiago Arturo Merino Benitez

mar. 11/4

11:15 pm-2:31 pm

1 stop17h 16m

$684

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 1/21

7:45 am-6:10 am

1 stop20h 25m

Santiago Arturo Merino Benitez

lun. 2/2

11:15 pm-5:59 pm

1 stop20h 44m

$704

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago

What is the cheapest month to book a flight from Charleston to Santiago?

Currently, April is the cheapest month in which you can book a flight from Charleston to Santiago (average of $752). Flying from Charleston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to SCL?

Find hourly flight availability from Charleston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

It’s optimal to fly from Charleston to Santiago at noon. By choosing this option you can save up to 13% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated septiembre 11, 2025.
Read reviews from past customers who have flown Delta and LATAM Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago?

    Airlines like LATAM Airlines fly from Charleston to Santiago in about 16h 41m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 4616 mi.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $532, Delta will fly you from Charleston to Santiago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $571. Delta is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Charleston to Santiago (average of $752). Flying from Charleston to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Santiago flights
Savannah to Santiago flights
Greenville to Santiago flights
Charlotte to Easter Island flights
Myrtle Beach to Santiago flights

Top 2 airlines flying from Charleston to Santiago

Discover the top 2 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$532Average$852FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$571Average$902FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.