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$704+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Nov 30 — Dec 71
Sun 11/30
Sun 12/7
1 adult, Economy
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Cheap flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$704
(Delta)

Popular in

July

Cheapest in

September

Average price

$673
Provider with most accurate pricing for Charleston-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Charleston-Santiago Arturo Merino Benitez flights.
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From Charleston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 33% potential increase in price ($447 potential increase over avg. RT price).
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Cheapest flight prices on average. 11% potential price decrease ($89 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2025.

This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:05 pmCHS - SCL
1 stop13h 45mUnited Airlines
Thu 12/2510:45 pmSCL - CHS
1 stop19h 25mUnited Airlines
Deal found 10/30$819
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:05 pmCHS - SCL
1 stop13h 45mUnited Airlines
Wed 12/2410:45 pmSCL - CHS
2 stops22h 33mUnited Airlines
Deal found 10/30$824
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1510:40 amCHS - SCL
1 stop19h 00mDelta
Tue 12/2311:10 pmSCL - CHS
1 stop16h 46mDelta
Deal found 10/30$828
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:00 amCHS - SCL
2 stops20h 35mLATAM Airlines
Thu 12/259:30 pmSCL - CHS
1 stop15h 00mLATAM Airlines
Deal found 10/30$834
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:05 pmCHS - SCL
1 stop13h 45mUnited Airlines
Sun 12/2110:45 pmSCL - CHS
2 stops22h 33mUnited Airlines
Deal found 10/30$864
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1611:00 amCHS - SCL
2 stops19h 50mUnited Airlines
Mon 12/2210:45 pmSCL - CHS
2 stops22h 33mUnited Airlines
Deal found 10/30$878
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amCHS - SCL
2 stops24h 50mUnited Airlines
Sun 12/2110:45 pmSCL - CHS
2 stops22h 33mUnited Airlines
Deal found 10/30$918
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1710:40 amCHS - SCL
2 stops17h 55mLATAM Airlines
Tue 12/2311:10 pmSCL - CHS
1 stop22h 21mLATAM Airlines
Deal found 10/30$934
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:51 pmCHS - SCL
2 stops15h 44mDelta
Sun 12/2111:10 pmSCL - CHS
1 stop16h 46mDelta
Deal found 10/30$974
This KAYAK deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:51 pmCHS - SCL
2 stops15h 44mLATAM Airlines
Fri 12/194:35 amSCL - CHS
2 stops21h 23mLATAM Airlines
Deal found 10/30$1,056
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:05 pmCHS - SCL
1 stop13h 45mUnited Airlines
Fri 12/1910:45 pmSCL - CHS
1 stop19h 25mUnited Airlines
Deal found 10/30$1,064

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 1/31

5:18 pm-3:30 pm

2 stops20h 12m

Santiago Arturo Merino Benitez

Thu 2/5

6:30 pm-2:06 pm

2 stops21h 36m

$704

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 1/31

5:18 pm-2:05 pm

2 stops18h 47m

Santiago Arturo Merino Benitez

Thu 2/5

11:10 pm-12:07 pm

1 stop14h 57m

$704

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 1/31

6:23 pm-9:00 am

1 stop12h 37m

Santiago Arturo Merino Benitez

Thu 2/5

11:15 pm-2:25 pm

1 stop17h 10m

$754

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 12/15

5:05 pm-8:50 am

1 stop13h 45m

Santiago Arturo Merino Benitez

Wed 12/24

10:45 pm-4:10 pm

1 stop19h 25m

$819

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 12/15

5:05 pm-8:50 am

1 stop13h 45m

Santiago Arturo Merino Benitez

Thu 12/25

10:45 pm-4:10 pm

1 stop19h 25m

$819

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 12/15

5:05 pm-8:50 am

1 stop13h 45m

Santiago Arturo Merino Benitez

Mon 12/22

10:45 pm-7:18 pm

2 stops22h 33m

$824

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 12/15

5:05 pm-8:50 am

1 stop13h 45m

Santiago Arturo Merino Benitez

Tue 12/23

10:45 pm-7:32 pm

2 stops22h 47m

$824

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Compare providers for flights from Charleston to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santiago in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago

What is the cheapest time of day to fly from CHS to SCL?

Find hourly flight availability from Charleston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 31, 2025.

It’s optimal to fly from Charleston to Santiago in the morning. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Charleston to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 31, 2025.
Read reviews from past customers who have flown Delta and LATAM Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,999 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,999 reviews
Delta
7.9
Good
7,999 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
LATAM Airlines
7.5
Good
1,873 reviews
Delta
7.9
Good
7,999 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago?

    Airlines like Delta and LATAM Airlines fly from Charleston to Santiago in about 18h 47m. The time it takes to get you to your destination can typically vary by up to 1h 25m. Airlines will cover a distance of 4616 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $532, Delta will fly you from Charleston to Santiago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $571. Delta is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Charleston to Santiago

Discover the top 2 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$532Average$852FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$571Average$1,072FlexibilityNo cancel feeOn-time81%

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