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$670+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$670
(Ovago)

Popular in

July

Cheapest in

September

Average price

$766
Provider with most accurate pricing for Charleston-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Charleston-Santiago Arturo Merino Benitez flights.
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From Charleston to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 23% potential increase in price ($307 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($88 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Ovago deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:30 amCHS - SCL
1 stop23h 10mLATAM Airlines
Thu 2/266:35 pmSCL - CHS
2 stops21h 25mLATAM Airlines
Deal found 1/6$670
This Ovago deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:55 pmCHS - SCL
2 stops20h 10mLATAM Airlines
Tue 7/288:40 pmSCL - CHS
1 stop13h 02mLATAM Airlines
Deal found 1/8$703
This LATAM Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:59 pmCHS - SCL
1 stop13h 16mLATAM Airlines
Fri 5/1511:05 pmSCL - CHS
2 stops19h 50mLATAM Airlines
Deal found 1/6$745
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:04 amCHS - SCL
1 stop19h 46mAmerican Airlines
Fri 5/158:30 pmSCL - CHS
1 stop16h 17mAmerican Airlines
Deal found 1/7$784
This LATAM Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:20 pmCHS - SCL
2 stops29h 05mLATAM Airlines
Sun 5/36:45 pmSCL - CHS
2 stops16h 30mLATAM Airlines
Deal found 1/7$797
This Gurufare deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:15 amCHS - SCL
2 stops19h 35mAvianca
Thu 2/2610:45 pmSCL - CHS
2 stops18h 04mAvianca
Deal found 1/6$798

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 2/19

6:30 am-7:40 am

1 stop23h 10m

Santiago Arturo Merino Benitez

Thu 2/26

6:35 pm-2:00 pm

2 stops21h 25m

$670

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 5/6

5:59 pm-7:15 am

1 stop13h 16m

Santiago Arturo Merino Benitez

Fri 5/15

11:05 pm-6:55 pm

2 stops19h 50m

$745

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 5/6

11:04 am-6:50 am

1 stop19h 46m

Santiago Arturo Merino Benitez

Fri 5/15

8:30 pm-12:47 pm

1 stop16h 17m

$784

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 4/29

12:20 pm-7:15 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Sun 5/3

11:05 pm-12:21 am

2 stops25h 16m

$797

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Thu 2/19

11:15 am-8:50 am

2 stops19h 35m

Santiago Arturo Merino Benitez

Thu 2/26

10:45 pm-2:49 pm

2 stops18h 04m

$798

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Compare providers for flights from Charleston to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 8, 2026.
Read reviews from past customers who have flown LATAM Airlines and American Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,901 reviews

Comfort

7.3

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,901 reviews
LATAM Airlines
7.5
Good
1,901 reviews

Comfort

7.3

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
American Airlines
7.2
Good
11,097 reviews
LATAM Airlines
7.5
Good
1,901 reviews

Comfort

7.3

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago?

    Airlines like LATAM Airlines and American Airlines fly from Charleston to Santiago in about 19h 46m. The time it takes to get you to your destination can typically vary by up to 3h 24m. Airlines will cover a distance of 4616 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $562, LATAM Airlines will fly you from Charleston to Santiago and back. In addition to LATAM Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $703. LATAM Airlines is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Greenville to Santiago flights
Savannah to Santiago flights
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Top 2 airlines flying from Charleston to Santiago

Discover the top 2 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$571Average$859FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$844FlexibilityNo cancel feeOn-time71%

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