HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$650+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Dec 29 — Jan 51
Mon 12/29
Mon 1/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$642
(LATAM Airlines)

Popular in

July

Cheapest in

September

Average price

$1,033
Provider with most accurate pricing for Charleston-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Santiago Arturo Merino Benitez flights.
Search Deals
From Charleston to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($354 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 11% potential price decrease ($93 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.

This LATAM Airlines deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:00 pmCHS - SCL
2 stops19h 05mLATAM Airlines
Wed 12/1011:10 pmSCL - CHS
1 stop12h 17mLATAM Airlines
Deal found 11/27$704
This Delta deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:15 amCHS - SCL
2 stops17h 45mDelta
Wed 12/108:15 amSCL - CHS
2 stops17h 35mDelta
Deal found 11/27$709
This KAYAK deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:30 amCHS - SCL
2 stops20h 55mLATAM Airlines
Sat 1/34:35 pmSCL - CHS
2 stops31h 15mLATAM Airlines
Deal found 11/27$1,536
This Delta deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:18 amCHS - SCL
2 stops18h 42mDelta
Sat 1/310:35 amSCL - CHS
2 stops15h 23mDelta
Deal found 11/28$1,949
This American Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:14 pmCHS - SCL
1 stop13h 11mAmerican Airlines
Sat 1/311:15 pmSCL - CHS
1 stop17h 33mAmerican Airlines
Deal found 11/28$2,130
This Copa Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:00 amCHS - SCL
2 stops18h 01mCopa Airlines
Fri 1/21:16 amSCL - CHS
2 stops19h 55mCopa Airlines
Deal found 11/28$3,627

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 29, 2025.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 1/26

12:00 pm-6:55 am

1 stop16h 55m

Santiago Arturo Merino Benitez

Mon 2/9

11:30 pm-5:11 pm

1 stop19h 41m

$650

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Mon 1/12

2:44 pm-6:10 am

1 stop13h 26m

Santiago Arturo Merino Benitez

Mon 1/19

9:30 pm-11:48 am

1 stop16h 18m

$664

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Sat 1/31

5:18 pm-3:30 pm

2 stops20h 12m

Santiago Arturo Merino Benitez

Thu 2/5

6:30 pm-2:06 pm

2 stops21h 36m

$704

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/28

Compare providers for flights from Charleston to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santiago in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Santiago

What is the cheapest time of day to fly from CHS to SCL?

Find hourly flight availability from Charleston to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 29, 2025.

It’s optimal to fly from Charleston to Santiago in the morning. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight in the afternoon.

How much does it cost to fly round-trip from Charleston to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 29, 2025.
Read reviews from past customers who have flown Delta and LATAM Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago?

    Airlines like LATAM Airlines fly from Charleston to Santiago in about 16h 55m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 4616 mi.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $532, Delta will fly you from Charleston to Santiago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on LATAM Airlines for as low as $571. Delta is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Santiago flights
Greenville to Santiago flights
Savannah to Santiago flights
Myrtle Beach to Santiago flights
Charlotte to Easter Island flights

Top 2 airlines flying from Charleston to Santiago

Discover the top 2 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$532Average$828FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$571Average$1,121FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.