HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$691+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
feb. 5 — feb. 121
jue. 2/5
jue. 2/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$691
(Ovago)

Popular in

July

Cheapest in

September

Average price

$766
Provider with most accurate pricing for Charleston-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Santiago Arturo Merino Benitez flights.
Search Deals
From Charleston to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($307 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($88 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Find flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 6, 2026.

This Ovago deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/197:30 amCHS - SCL
1 stop22h 10mLATAM Airlines
jue. 2/266:30 pmSCL - CHS
2 stops16h 53mLATAM Airlines
Deal found 1/4$691
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/54:33 pmCHS - SCL
1 stop14h 42mDelta
lun. 5/188:40 pmSCL - CHS
1 stop17h 05mDelta
Deal found 1/5$705
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 1/312:04 pmCHS - SCL
2 stops16h 56mAmerican Airlines
jue. 2/510:35 pmSCL - CHS
1 stop12h 12mAmerican Airlines
Deal found 1/4$710
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/62:31 pmCHS - SCL
1 stop16h 44mDelta
dom. 5/178:40 pmSCL - CHS
1 stop14h 44mDelta
Deal found 1/5$745
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/62:15 pmCHS - SCL
2 stops16h 35mAmerican Airlines
vie. 5/158:30 pmSCL - CHS
2 stops16h 15mAmerican Airlines
Deal found 1/5$750
This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/195:10 pmCHS - SCL
1 stop13h 40mUnited Airlines
jue. 2/2610:45 pmSCL - CHS
1 stop25h 13mUnited Airlines
Deal found 1/4$759
This Expedia deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/64:33 pmCHS - SCL
2 stops14h 22mLATAM Airlines
vie. 5/158:30 amSCL - CHS
3 stops26h 54mLATAM Airlines
Deal found 1/5$780
This KAYAK deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/94:30 pmCHS - SCL
1 stop14h 45mLATAM Airlines
dom. 5/1711:05 pmSCL - CHS
2 stops24h 51mLATAM Airlines
Deal found 1/5$784
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/87:59 pmCHS - SCL
1 stop11h 16mDelta
dom. 5/178:40 pmSCL - CHS
1 stop18h 59mDelta
Deal found 1/5$785
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/511:04 amCHS - SCL
1 stop19h 46mAmerican Airlines
vie. 5/158:30 pmSCL - CHS
1 stop16h 17mAmerican Airlines
Deal found 1/6$795

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 6, 2026.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

jue. 2/19

7:30 am-7:40 am

1 stop22h 10m

Santiago Arturo Merino Benitez

jue. 2/26

6:30 pm-9:23 am

2 stops16h 53m

$691

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 5/6

12:04 pm-6:50 am

1 stop18h 46m

Santiago Arturo Merino Benitez

lun. 5/18

8:40 pm-1:45 pm

1 stop17h 05m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

sáb. 1/31

6:23 pm-9:00 am

1 stop12h 37m

Santiago Arturo Merino Benitez

jue. 2/5

10:30 pm-5:27 pm

1 stop20h 57m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mar. 5/5

7:30 am-5:45 am

2 stops22h 15m

Santiago Arturo Merino Benitez

mar. 5/12

11:05 pm-11:56 pm

2 stops24h 51m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mar. 5/5

5:59 pm-2:05 pm

2 stops20h 06m

Santiago Arturo Merino Benitez

jue. 5/14

7:45 pm-4:51 pm

2 stops21h 06m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mar. 5/5

7:30 am-5:45 am

2 stops22h 15m

Santiago Arturo Merino Benitez

dom. 5/17

11:05 pm-11:56 pm

2 stops24h 51m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

jue. 5/7

5:55 pm-7:15 am

1 stop13h 20m

Santiago Arturo Merino Benitez

jue. 5/14

7:45 am-11:56 pm

2 stops16h 11m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

mié. 5/6

5:59 pm-7:15 am

1 stop13h 16m

Santiago Arturo Merino Benitez

lun. 5/18

5:40 am-11:56 pm

2 stops18h 16m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

jue. 5/7

9:30 am-7:15 am

1 stop21h 45m

Santiago Arturo Merino Benitez

lun. 5/18

8:40 pm-9:42 am

1 stop13h 02m

$705

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

jue. 5/7

7:59 pm-7:15 am

1 stop11h 16m

Santiago Arturo Merino Benitez

lun. 5/18

4:50 pm-6:55 pm

2 stops26h 05m

$705

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/4

Compare providers for flights from Charleston to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated enero 6, 2026.
Read reviews from past customers who have flown LATAM Airlines and American Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,900 reviews

Food

6.7

Comfort

7.3

Overall

7.5

Entertainment

7.0

Boarding

7.6

Crew

8.1

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,900 reviews
LATAM Airlines
7.5
Good
1,900 reviews

Food

6.7

Comfort

7.3

Overall

7.5

Entertainment

7.0

Boarding

7.6

Crew

8.1

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
American Airlines
7.2
Good
11,086 reviews
LATAM Airlines
7.5
Good
1,900 reviews

Food

6.7

Comfort

7.3

Overall

7.5

Entertainment

7.0

Boarding

7.6

Crew

8.1

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago?

    Airlines like LATAM Airlines and Delta fly from Charleston to Santiago in about 18h 46m. The time it takes to get you to your destination can typically vary by up to 3h 24m. Airlines will cover a distance of 4616 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $562, LATAM Airlines will fly you from Charleston to Santiago and back. In addition to LATAM Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $703. LATAM Airlines is priced at 42% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Santiago flights
Savannah to Santiago flights
Greenville to Santiago flights
Myrtle Beach to Santiago flights
Charlotte to Easter Island flights

Top 2 airlines flying from Charleston to Santiago

Discover the top 2 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$571Average$859FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$844FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.