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$725+ Cheap flights from Charleston (CHS) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SCL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Charleston to Santiago

Cheapest flights from Charleston to Santiago
Explore the most affordable flight options available from Charleston to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:45 am
CHS
-
SCL
1 stop18h 05m
Delta
Wed 11/1811:25 pm
SCL
-
CHS
2 stops21h 29m
Delta
Deal found 1/28$725
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:07 am
CHS
-
SCL
3 stops30h 08m
Multiple Airlines
Mon 4/134:56 am
SCL
-
CHS
3 stops41h 37m
Multiple Airlines
Deal found 1/27$758
This LATAM Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/41:04 pm
CHS
-
SCL
1 stop16h 36m
LATAM Airlines
Wed 3/1110:10 pm
SCL
-
CHS
1 stop12h 34m
LATAM Airlines
Deal found 1/27$783
This LATAM Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:57 pm
CHS
-
SCL
2 stops23h 28m
LATAM Airlines
Sun 5/311:05 pm
SCL
-
CHS
2 stops19h 33m
LATAM Airlines
Deal found 1/28$797
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:07 am
CHS
-
SCL
3 stops19h 10m
Multiple Airlines
Thu 3/192:09 am
SCL
-
CHS
2 stops21h 24m
Multiple Airlines
Deal found 1/27$809
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:06 am
CHS
-
SCL
1 stop20h 04m
American Airlines
Mon 4/138:30 pm
SCL
-
CHS
1 stop13h 54m
American Airlines
Deal found 1/28$823
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:07 am
CHS
-
SCL
3 stops30h 08m
Multiple Airlines
Mon 4/134:56 am
SCL
-
CHS
3 stops41h 37m
Multiple Airlines
Deal found 1/27$850

Find flight deals from Charleston to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$758
(Mytrip)

Popular in

July

Cheapest in

September

Average price

$766
Provider with most accurate pricing for Charleston-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Santiago Arturo Merino Benitez flights.
Search Deals
From Charleston to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($303 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($88 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Charleston to Santiago that are best for you.

Fly from

Charleston

Fly to

Santiago

Route

Depart

Return

Price

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Fri 4/3

8:07 am-3:15 pm

3 stops30h 08m

Santiago Arturo Merino Benitez

Mon 4/13

4:56 am-10:33 pm

3 stops41h 37m

$758

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 3/4

3:07 pm-7:40 am

1 stop14h 33m

Santiago Arturo Merino Benitez

Tue 3/10

12:20 am-7:34 pm

2 stops20h 14m

$783

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Wed 4/29

5:57 pm-7:15 am

1 stop13h 18m

Santiago Arturo Merino Benitez

Sun 5/3

11:05 pm-6:38 pm

2 stops19h 33m

$797

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Fri 4/3

11:06 am-8:10 am

1 stop20h 04m

Santiago Arturo Merino Benitez

Mon 4/13

8:30 pm-10:24 am

1 stop13h 54m

$823

CharlestonSantiago

CHS - SCL

CHSSCL

Charleston

Fri 4/3

4:51 pm-8:15 am

1 stop14h 24m

Santiago Arturo Merino Benitez

Mon 4/13

5:40 am-12:22 am

2 stops18h 42m

$823

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Compare providers for flights from Charleston to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Delta, LATAM Airlines, and American Airlines from Charleston to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,917 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Santiago?

    Airlines like LATAM Airlines fly from Charleston to Santiago in about 14h 33m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 4616 mi.

  • What are the cheapest airlines flying from Charleston to Santiago round-trip?

    Currently priced at $532, Delta will fly you from Charleston to Santiago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from LATAM Airlines and American Airlines - these airlines can fly you to your destination from $562 and $703, respectively. Delta is priced at 45% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Charleston to Santiago that include hotel bookings?

    Yes. In addition to deals on Charleston to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Santiago.

  • Can I find deals for business class flights from Charleston to Santiago?

    Yes. Cheapflights offers flight deals from Charleston to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Charleston to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Myrtle Beach to Santiago flights
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Top 3 airlines flying from Charleston to Santiago

Discover the top 3 airlines that operate flights from Charleston to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$532Average$828FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$562Average$859FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$703Average$845FlexibilityNo cancel feeOn-time71%

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