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$253+ Cheap flights from Cancún (CUN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
CUN — SCL
May 29 — Jun 51
Fri 5/29
Fri 6/5
1 adult, Economy
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Cheap flight deals from Cancún to Santiago

Cheapest flights from Cancún to Santiago
Explore the most affordable flight options available from Cancún to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.

This Arajet deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Mon 9/216:00 am
SCL
-
CUN
1 stop13h 12m
Arajet
Deal found 4/29$476
This Arajet deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Thu 8/273:35 am
SCL
-
CUN
1 stop13h 19m
Arajet
Deal found 4/25$478
This Arajet deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Mon 10/196:00 am
SCL
-
CUN
1 stop13h 12m
Arajet
Deal found 4/27$531
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Fri 6/1212:01 am
SCL
-
CUN
1 stop12h 34m
Arajet
Deal found 4/27$539
This Arajet deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Fri 10/3012:55 am
SCL
-
CUN
1 stop12h 40m
Arajet
Deal found 4/26$546
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Thu 6/113:35 am
SCL
-
CUN
1 stop13h 19m
Arajet
Deal found 4/27$553
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/132:32 pm
CUN
-
SCL
1 stop12h 23m
Arajet
Fri 9/2512:55 am
SCL
-
CUN
1 stop12h 40m
Arajet
Deal found 4/26$563
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Tue 6/163:35 am
SCL
-
CUN
1 stop12h 59m
Arajet
Deal found 4/27$565
This Arajet deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Fri 10/164:35 am
SCL
-
CUN
1 stop13h 19m
Arajet
Deal found 4/27$572
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Thu 6/113:35 am
SCL
-
CUN
1 stop13h 19m
Arajet
Deal found 4/26$579
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Fri 6/1212:01 am
SCL
-
CUN
1 stop12h 34m
Arajet
Deal found 4/27$588
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
CUN
-
SCL
1 stop13h 00m
Arajet
Tue 6/93:35 am
SCL
-
CUN
1 stop12h 59m
Arajet
Deal found 4/26$591

Find flight deals from Cancún to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cancún (CUN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$474
(Arajet)

One-way from

$253
(Arajet)

Popular in

January

Cheapest in

September

Average price

$593
Provider with most accurate pricing for Cancun-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cancun-Santiago Arturo Merino Benitez flights.
Search Deals
From Cancun to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Cancun to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($89 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cancún to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Cancún to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 8/25

12:35 pm-2:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Mon 9/21

6:00 am-5:12 pm

1 stop13h 12m

$476

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Thu 10/1

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Fri 10/30

12:55 am-11:35 am

1 stop12h 40m

$546

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 10/13

12:35 pm-3:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Fri 10/16

4:35 am-3:54 pm

1 stop13h 19m

$572
Quickest round-trip

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 9/16

4:50 pm-5:45 am

1 stop10h 55m

Santiago Arturo Merino Benitez

Wed 9/23

4:35 am-3:34 pm

1 stop12h 59m

$649

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 9/1

12:35 pm-2:35 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Wed 9/23

4:35 am-3:34 pm

1 stop12h 59m

$687

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 9/16

4:05 pm-4:50 am

1 stop10h 45m

Santiago Arturo Merino Benitez

Thu 10/1

9:25 pm-8:30 pm

2 stops25h 05m

$701

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Wed 9/16

6:45 pm-5:45 am

1 stop9h 00m

Santiago Arturo Merino Benitez

Wed 9/23

7:45 pm-8:30 pm

2 stops26h 45m

$701
Cheapest one-way

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 8/25

12:35 pm-2:35 am

1 stop13h 00m

$253

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Sun 10/25

11:55 am-4:55 am

1 stop15h 00m

$266

CancúnSantiago

CUN - SCL

CUNSCL

Cancun

Tue 9/1

12:35 pm-2:35 am

1 stop13h 00m

$267

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 16 resultsSorted by cheapest first
1
2
  • Most accurate provider: When it comes to deals on Cancún-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cancún-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cancún-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cancún-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cancún-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cancún to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cancún with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cancún to Santiago

How far ahead should I book a flight from Cancún to Santiago?

To ensure you get the cheapest price possible for a flight from Cancún to Santiago, you should look to book at least 16 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cancún to Santiago?

Currently, September is the cheapest month in which you can book a flight from Cancún to Santiago (average of $455). Flying from Cancún to Santiago in January is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Cancún to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 29, 2026.
Read through reviews of airlines operating flights from Cancún to Santiago, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.4
Good
1,912 reviews

Entertainment

7.0

Food

6.7

Overall

7.4

Comfort

7.3

Crew

8.0

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.4
Good
1,912 reviews
LATAM Airlines
7.4
Good
1,912 reviews

Entertainment

7.0

Food

6.7

Overall

7.4

Comfort

7.3

Crew

8.0

Boarding

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Cancún to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cancún to Santiago?

    Arajet can get you from Cancún to Santiago in just under 13h. Your travel time can differ by up to . There are 3905 mi between Cancún and Santiago.

  • What is the cheapest airline to fly from Cancún to Santiago round-trip?

    Our cheapest airline available from Cancún to Santiago is LATAM Airlines. Our recent data shows that you can find tickets from as low as $608 on this airline.

  • What are the cheapest airlines to fly from Cancún to Santiago one-way?

    For one-way options, check prices for Sky Airline. According to our data, you can fly for as low as $201. Users have also found prices from $261 and $272 on Copa Airlines and Avianca, respectively.

  • Can I find deals for flights from Cancún to Santiago that include hotel bookings?

    Yes. In addition to deals on Cancún to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cancún to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cancún to Santiago.

  • Can I find deals for business class flights from Cancún to Santiago?

    Yes. Cheapflights offers flight deals from Cancún to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cancún to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Cancún to Santiago (average of $455). Flying from Cancún to Santiago in January is currently the most expensive (average of $743). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Santiago car rentals
Santiago Arturo Merino Benitez Airport car rentals
Lastarria car rentals

Top airline flying from Cancún to Santiago

Discover the top airline that operate flights from Cancún to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$608Average$849FlexibilityNo cancel feeOn-time81%

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