HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$715+ Cheap flights from Buffalo (BUF) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SCL
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Buffalo to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Buffalo to Santiago

Cheapest flights from Buffalo to Santiago
Explore the most affordable flight options available from Buffalo to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amBUF - SCL
2 stops21h 35mDelta
Sun 12/289:30 pmSCL - BUF
2 stops21h 42mDelta
Deal found 12/13$809
This Expedia deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amBUF - SCL
3 stops30h 30mLATAM Airlines
Sun 12/281:35 pmSCL - BUF
2 stops36h 12mLATAM Airlines
Deal found 12/13$1,299
This oojo deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:10 amBUF - SCL
3 stops30h 00mMultiple Airlines
Sun 12/283:05 pmSCL - BUF
3 stops26h 27mMultiple Airlines
Deal found 12/13$3,232

Find flight deals from Buffalo to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$715
(LATAM Airlines)
Provider with most accurate pricing for Buffalo-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Santiago Arturo Merino Benitez flights.
Search Deals
From Buffalo to Santiago Arturo Merino Benitez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Buffalo to Santiago that are best for you.

Fly from

Buffalo

Fly to

Santiago

Route

Depart

Return

Price

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Wed 1/28

3:38 pm-2:05 pm

2 stops20h 27m

Santiago Arturo Merino Benitez

Wed 2/4

11:30 pm-2:58 pm

1 stop17h 28m

$732

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Thu 1/29

12:14 pm-7:40 am

1 stop17h 26m

Santiago Arturo Merino Benitez

Thu 2/5

11:30 pm-2:58 pm

1 stop17h 28m

$764

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Wed 1/28

11:24 am-8:50 am

2 stops19h 26m

Santiago Arturo Merino Benitez

Wed 2/4

10:45 pm-5:40 pm

2 stops20h 55m

$769

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Thu 1/29

4:17 pm-9:00 am

2 stops14h 43m

Santiago Arturo Merino Benitez

Thu 2/5

10:35 pm-4:57 pm

2 stops20h 22m

$769

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Sun 1/18

7:45 pm-6:55 am

1 stop33h 10m

Santiago Arturo Merino Benitez

Mon 1/26

8:50 pm-11:28 pm

2 stops28h 38m

$771

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Fri 3/20

3:56 pm-5:55 am

1 stop12h 59m

Santiago Arturo Merino Benitez

Tue 3/24

1:40 pm-3:14 pm

2 stops26h 34m

$804

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Sat 12/20

12:02 pm-6:55 am

1 stop16h 53m

$770

BuffaloSantiago

BUF - SCL

BUFSCL

Buffalo

Sun 12/21

12:07 pm-7:40 am

1 stop17h 33m

$796

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Compare providers for flights from Buffalo to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santiago in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
SmartFaresPrice Accuracy1 starTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 16, 2025.
Get a feel of what it's like to fly with LATAM Airlines from Buffalo to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,891 reviews

Entertainment

7.0

Food

6.7

Crew

8.1

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,891 reviews
LATAM Airlines
7.5
Good
1,891 reviews

Entertainment

7.0

Food

6.7

Crew

8.1

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santiago?

    LATAM Airlines, United Airlines, and American Airlines can get you from Buffalo to Santiago in just under 14h 43m. Your travel time can differ by up to 5h 44m. The distance between Buffalo and Santiago is about 5294 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Buffalo to Santiago round-trip?

    Flying on LATAM Airlines is currently your cheapest option to Santiago, with prices starting at $763.

  • Can I find deals for flights from Buffalo to Santiago that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santiago.

  • Can I find deals for business class flights from Buffalo to Santiago?

    Yes. Cheapflights offers flight deals from Buffalo to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Buffalo to Santiago

Discover the top airline that operate flights from Buffalo to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$763Average$844FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.