HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Fe

$264+ Cheap flights from South Carolina to Santa Fe (SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAF
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Santa Fe with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Santa Fe

Keep the following information in mind while searching for South Carolina to Santa Fe flight deals. Data was last updated June 12, 2025.

Round-trip from

$264
(American Airlines)
From South Carolina to Santa Fe
Search Deals

Find flight deals from South Carolina to Santa Fe

Cheapest flights from South Carolina to Santa Fe
Explore the most affordable flight options available from South Carolina to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/237:14 amGSP - SAF
1 stop8h 20mAmerican Airlines
Sat 8/309:51 amSAF - GSP
1 stop4h 58mAmerican Airlines
Deal found 6/9$264
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/105:00 amCHS - SAF
1 stop6h 25mAmerican Airlines
Sat 7/124:48 pmSAF - CHS
1 stop6h 08mAmerican Airlines
Deal found 6/9$264
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/305:43 amCLT - SAF
1 stop5h 42mAmerican Airlines
Tue 8/59:55 amSAF - CLT
1 stop8h 35mAmerican Airlines
Deal found 6/9$264
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/264:27 pmCLT - SAF
1 stop7h 33mUnited Airlines
Sun 8/317:15 amSAF - CLT
2 stops8h 00mUnited Airlines
Deal found 6/12$439
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/197:00 amCHS - SAF
1 stop6h 29mUnited Airlines
Thu 7/247:05 amSAF - CHS
2 stops25h 09mUnited Airlines
Deal found 6/10$497
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/214:25 pmGSP - SAF
1 stop7h 33mUnited Airlines
Fri 7/255:59 pmSAF - GSP
2 stops18h 18mUnited Airlines
Deal found 6/11$522

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from South Carolina to Santa Fe that are best for you.

Fly from

South Carolina

Fly to

Santa Fe

Route

Depart

Return

Price

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Sat 8/23

7:14 am-1:34 pm

1 stop8h 20m

Santa Fe

Sat 8/30

9:51 am-4:49 pm

1 stop4h 58m

$264

CharlestonSanta Fe

CHS - SAF

CHSSAF

Charleston

Thu 7/10

5:00 am-9:25 am

1 stop6h 25m

Santa Fe

Sat 7/12

4:48 pm-12:56 am

1 stop6h 08m

$264

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Wed 7/30

5:43 am-9:25 am

1 stop5h 42m

Santa Fe

Tue 8/5

9:55 am-8:30 pm

1 stop8h 35m

$264

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Tue 8/26

4:27 pm-10:00 pm

1 stop7h 33m

Santa Fe

Sun 8/31

7:15 am-5:15 pm

2 stops8h 00m

$439

CharlestonSanta Fe

CHS - SAF

CHSSAF

Charleston

Sat 7/19

7:00 am-11:29 am

1 stop6h 29m

Santa Fe

Thu 7/24

7:05 am-10:14 am

2 stops25h 09m

$497

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Mon 7/21

4:25 pm-9:58 pm

1 stop7h 33m

Santa Fe

Fri 7/25

5:59 pm-2:17 pm

2 stops18h 18m

$522

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Sun 7/20

2:34 pm-6:48 pm

1 stop6h 14m

$295

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Fri 10/3

4:27 pm-9:24 am

1 stop18h 57m

$362

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from South Carolina to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santa Fe

What is the cheapest month to book a flight from South Carolina to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santa Fe (average of $372). Flying from South Carolina to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SAF?

Find hourly flight availability from South Carolina to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from South Carolina to Santa Fe, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Santa Fe by month

Plan your trip to Santa Fe by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santa Fe ranges from 0.5 - 2.6 inches per month. August is typically the wettest month, when rainfall can reach 2.6 in. February is typically the driest time to visit Santa Fe when rainfall is around 0.5 in.

Temperature in Santa Fe by month

Plan your trip to Santa Fe by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santa Fe, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated June 12, 2025.
See what other customers who have flown with United Airlines and American Airlines from South Carolina to Santa Fe have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,790 reviews

Overall

7.4

Entertainment

7.0

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,790 reviews
United Airlines
7.4
Good
8,790 reviews

Overall

7.4

Entertainment

7.0

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,790 reviews

Overall

7.4

Entertainment

7.0

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from South Carolina?

    If you book a flight to Santa Fe from South Carolina, you will be flying to Santa Fe, which is the city’s only airport. Santa Fe (SAF) is located 9.8 mi from the center of Santa Fe.

  • What are the most popular routes from South Carolina to Santa Fe?

    While some choose either Charleston - Santa Fe or Greenville - Santa Fe, Charlotte Douglas - Santa Fe is the most popular route from South Carolina to Santa Fe.

  • Can I find deals for flights from South Carolina to Santa Fe that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santa Fe.

  • Can I find deals for business class flights from South Carolina to Santa Fe?

    Yes. Cheapflights offers flight deals from South Carolina to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Santa Fe (average of $372). Flying from South Carolina to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Santa Rosa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to El Paso flights
O'Hare Intl to Albuquerque flights
San Francisco to Albuquerque flights
Hobby to El Paso flights
Los Angeles to Albuquerque flights
Newark to Albuquerque flights
Portland to Albuquerque flights
Dallas/Fort Worth to Albuquerque flights
LaGuardia to Albuquerque flights
Seattle to Albuquerque flights
John F Kennedy Intl to Albuquerque flights
George Bush Intcntl to El Paso flights
Atlanta to Albuquerque flights
Dulles Intl to Albuquerque flights
Reagan-National to Albuquerque flights
Baltimore to Albuquerque flights
O'Hare Intl to El Paso flights
San Antonio to El Paso flights
Love Field to El Paso flights
Austin to El Paso flights
Los Angeles to El Paso flights
Seattle to El Paso flights
Hobby to Albuquerque flights
Las Vegas to El Paso flights
Dallas/Fort Worth to Santa Fe flights
Denver to El Paso flights
Minneapolis to Albuquerque flights
Philadelphia to Albuquerque flights
Newark to Santa Fe flights
Boston to Albuquerque flights
LaGuardia to Santa Fe flights
Atlanta to El Paso flights
George Bush Intcntl to Albuquerque flights
Austin to Albuquerque flights
Ontario to Albuquerque flights
John F Kennedy Intl to El Paso flights
Philadelphia to Santa Fe flights
Ontario to El Paso flights
Denver to Albuquerque flights
Newark to El Paso flights
Love Field to Albuquerque flights
Midway to Albuquerque flights
Dulles Intl to Santa Fe flights
Kansas City to Albuquerque flights
Reagan-National to Santa Fe flights
Sacramento to Albuquerque flights
Reagan-National to El Paso flights
Orlando to Albuquerque flights
Pittsburgh to Albuquerque flights
Boston to Santa Fe flights

Top airline flying from South Carolina to Santa Fe

Discover the top airline that operate flights from South Carolina to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$223Average$572FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.