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$264+ Cheap flights from South Carolina to Santa Fe (SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAF
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from South Carolina to Santa Fe

Keep the following information in mind while searching for South Carolina to Santa Fe flight deals. Data was last updated July 31, 2025.

Round-trip from

$264
(American Airlines)
From South Carolina to Santa Fe
Search Deals

Find flight deals from South Carolina to Santa Fe

Cheapest flights from South Carolina to Santa Fe
Explore the most affordable flight options available from South Carolina to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/102:54 pmCHS - SAF
1 stop8h 12mAmerican Airlines
Wed 9/176:15 amSAF - CHS
1 stop5h 48mAmerican Airlines
Deal found 7/31$264
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/108:50 amCLT - SAF
1 stop8h 01mAmerican Airlines
Sat 9/136:15 amSAF - CLT
1 stop5h 28mAmerican Airlines
Deal found 7/30$264
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:12 pmGSP - SAF
1 stop5h 58mAmerican Airlines
Fri 10/242:07 pmSAF - GSP
1 stop6h 24mAmerican Airlines
Deal found 7/31$319
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/124:27 pmCLT - SAF
1 stop18h 56mUnited Airlines
Tue 9/1610:45 amSAF - CLT
2 stops11h 14mUnited Airlines
Deal found 7/31$462
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:11 pmCHS - SAF
1 stop7h 48mUnited Airlines
Mon 11/177:00 amSAF - CHS
1 stop6h 06mUnited Airlines
Deal found 7/30$499
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/44:29 pmGSP - SAF
1 stop18h 55mUnited Airlines
Sat 10/1110:45 amSAF - GSP
2 stops11h 01mUnited Airlines
Deal found 7/30$582
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:21 pmHHH - SAF
2 stops23h 26mAmerican Airlines
Sat 12/134:19 pmSAF - HHH
2 stops23h 11mAmerican Airlines
Deal found 7/29$812

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from South Carolina to Santa Fe that are best for you.

Fly from

South Carolina

Fly to

Santa Fe

Route

Depart

Return

Price

CharlestonSanta Fe

CHS - SAF

CHSSAF

Charleston

Wed 9/10

2:54 pm-9:06 pm

1 stop8h 12m

Santa Fe

Wed 9/17

6:15 am-2:03 pm

1 stop5h 48m

$264

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Wed 9/10

3:39 pm-9:56 pm

1 stop8h 17m

Santa Fe

Thu 9/18

2:05 pm-12:10 am

1 stop8h 05m

$264

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Sat 10/18

6:12 pm-10:10 pm

1 stop5h 58m

Santa Fe

Fri 10/24

2:07 pm-10:31 pm

1 stop6h 24m

$319

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Fri 9/12

4:27 pm-9:23 am

1 stop18h 56m

Santa Fe

Tue 9/16

10:45 am-11:59 pm

2 stops11h 14m

$462

CharlestonSanta Fe

CHS - SAF

CHSSAF

Charleston

Fri 11/14

4:11 pm-9:59 pm

1 stop7h 48m

Santa Fe

Mon 11/17

7:00 am-3:06 pm

1 stop6h 06m

$499

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Sat 10/4

4:29 pm-9:24 am

1 stop18h 55m

Santa Fe

Sat 10/11

10:45 am-11:46 pm

2 stops11h 01m

$582

Hilton Head IslandSanta Fe

HHH - SAF

HHHSAF

Hilton Head Island

Wed 12/10

6:21 pm-3:47 pm

2 stops23h 26m

Santa Fe

Sat 12/13

4:19 pm-5:30 pm

2 stops23h 11m

$812

GreenvilleSanta Fe

GSP - SAF

GSPSAF

Greenville

Fri 8/15

5:43 pm-9:59 pm

1 stop6h 16m

$385

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Tue 8/12

4:29 pm-9:59 pm

1 stop7h 30m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from South Carolina to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santa Fe

What is the cheapest month to book a flight from South Carolina to Santa Fe?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santa Fe (average of $372). Flying from South Carolina to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SAF?

Find hourly flight availability from South Carolina to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from South Carolina to Santa Fe, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santa Fe

Get insights into the airlines that provide service to Santa Fe. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Fe. Reviews last updated July 31, 2025.
See what other customers who have flown with United Airlines and American Airlines from South Carolina to Santa Fe have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,900 reviews

Comfort

7.3

Boarding

7.7

Food

6.6

Crew

8.1

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,900 reviews
United Airlines
7.4
Good
8,900 reviews

Comfort

7.3

Boarding

7.7

Food

6.6

Crew

8.1

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,900 reviews

Comfort

7.3

Boarding

7.7

Food

6.6

Crew

8.1

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from South Carolina?

    If you book a flight to Santa Fe from South Carolina, you will be flying to Santa Fe, which is the city’s only airport. Santa Fe (SAF) is located 9.8 mi from the center of Santa Fe.

  • What are the most popular routes from South Carolina to Santa Fe?

    While some choose either Charleston - Santa Fe or Greenville - Santa Fe, Charlotte Douglas - Santa Fe is the most popular route from South Carolina to Santa Fe.

  • Can I find deals for flights from South Carolina to Santa Fe that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santa Fe.

  • Can I find deals for business class flights from South Carolina to Santa Fe?

    Yes. Cheapflights offers flight deals from South Carolina to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santa Fe?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Santa Fe (average of $372). Flying from South Carolina to Santa Fe in March is currently the most expensive (average of $536). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Top airline flying from South Carolina to Santa Fe

Discover the top airline that operate flights from South Carolina to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$263Average$594FlexibilityNo cancel feeOn-time71%

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