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$214+ Cheap flights from Ohio to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — SAF
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Find flight deals from Ohio to Santa Fe

Cheapest flights from Ohio to Santa Fe
Explore the most affordable flight options available from Ohio to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amCVG - SAF
1 stop8h 46mAmerican Airlines
Sun 12/146:15 amSAF - CVG
1 stop7h 46mAmerican Airlines
Deal found 10/19$254
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/109:07 amDTW - SAF
1 stop5h 33mUnited Airlines
Sat 11/151:25 pmSAF - DTW
1 stop6h 52mUnited Airlines
Deal found 10/20$264
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:35 amCMH - SAF
1 stop6h 50mAmerican Airlines
Sun 12/144:51 pmSAF - CMH
1 stop5h 29mAmerican Airlines
Deal found 10/20$264
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:02 amCLE - SAF
1 stop6h 26mAmerican Airlines
Wed 11/196:15 amSAF - CLE
1 stop8h 17mAmerican Airlines
Deal found 10/21$265
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:11 amDTW - SAF
1 stop6h 17mAmerican Airlines
Tue 11/186:15 amSAF - DTW
1 stop6h 45mAmerican Airlines
Deal found 10/20$319
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:45 amCLE - SAF
1 stop8h 12mUnited Airlines
Sun 11/97:00 amSAF - CLE
1 stop6h 13mUnited Airlines
Deal found 10/21$332
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:02 amCLE - SAF
1 stop6h 26mAmerican Airlines
Sat 11/224:56 pmSAF - CLE
1 stop5h 39mAmerican Airlines
Deal found 10/21$339
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:10 amDTW - SAF
1 stop9h 45mAmerican Airlines
Wed 12/1012:36 pmSAF - DTW
1 stop8h 19mAmerican Airlines
Deal found 10/19$344
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:00 amCMH - SAF
1 stop8h 35mAmerican Airlines
Sat 11/86:15 amSAF - CMH
1 stop6h 13mAmerican Airlines
Deal found 10/21$349
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:31 amCVG - SAF
2 stops12h 26mUnited Airlines
Sat 11/157:00 amSAF - CVG
1 stop5h 17mUnited Airlines
Deal found 10/20$350
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:30 pmDTW - SAF
1 stop7h 29mUnited Airlines
Tue 11/181:25 pmSAF - DTW
2 stops8h 10mUnited Airlines
Deal found 10/20$354
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:10 amCMH - SAF
2 stops8h 31mUnited Airlines
Sat 11/87:00 amSAF - CMH
1 stop5h 58mUnited Airlines
Deal found 10/21$359

Cheap flight deals from Ohio to Santa Fe

Keep the following information in mind while searching for Ohio to Santa Fe flight deals. Data was last updated October 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$254
(American Airlines)

One-way from

$214
(American Airlines)

Popular in

October

Cheapest in

July

Average price

$631
Provider with most accurate pricing for Cleveland Hopkins Intl-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Santa Fe flights.
Search Deals
From Ohio to Santa Fe
Search Deals
One-way flight from Ohio to Santa Fe
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Ohio to Santa Fe that are best for you.

Fly from

Ohio

Fly to

Santa Fe

Route

Depart

Return

Price

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Mon 11/10

9:07 am-12:40 pm

1 stop5h 33m

Santa Fe

Sat 11/15

1:25 pm-10:17 pm

1 stop6h 52m

$264

ColumbusSanta Fe

CMH - SAF

CMHSAF

Columbus

Wed 12/10

11:35 am-4:25 pm

1 stop6h 50m

Santa Fe

Sun 12/14

4:51 pm-12:20 am

1 stop5h 29m

$264

PittsburghSanta Fe

PIT - SAF

PITSAF

Pittsburgh

Fri 1/23

8:15 am-2:54 pm

1 stop8h 39m

Santa Fe

Mon 1/26

1:16 pm-10:56 pm

1 stop7h 40m

$264

ColumbusSanta Fe

CMH - SAF

CMHSAF

Columbus

Thu 1/22

7:30 am-2:53 pm

1 stop9h 23m

Santa Fe

Wed 1/28

10:28 am-8:10 pm

1 stop7h 42m

$264

ClevelandSanta Fe

CLE - SAF

CLESAF

Cleveland Hopkins Intl

Thu 11/13

5:02 am-9:28 am

1 stop6h 26m

Santa Fe

Wed 11/19

6:15 am-4:32 pm

1 stop8h 17m

$265

ClevelandSanta Fe

CLE - SAF

CLESAF

Cleveland Hopkins Intl

Thu 2/19

6:50 am-3:47 pm

2 stops10h 57m

Santa Fe

Thu 2/26

10:52 am-8:10 pm

1 stop7h 18m

$274

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Fri 11/14

5:11 am-9:28 am

1 stop6h 17m

Santa Fe

Tue 11/18

12:32 pm-10:55 pm

1 stop8h 23m

$319

ClevelandSanta Fe

CLE - SAF

CLESAF

Cleveland Hopkins Intl

Wed 11/5

10:45 am-4:57 pm

1 stop8h 12m

Santa Fe

Sun 11/9

7:00 am-3:13 pm

1 stop6h 13m

$332

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Sat 12/6

7:10 am-2:55 pm

1 stop9h 45m

Santa Fe

Wed 12/10

12:36 pm-10:55 pm

1 stop8h 19m

$344

DetroitSanta Fe

DTW - SAF

DTWSAF

Detroit Metropolitan Wayne County

Tue 11/4

7:24 am-2:52 pm

1 stop9h 28m

Santa Fe

Sat 11/8

6:15 am-3:00 pm

1 stop6h 45m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 39 results
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Best time to book a flight from Ohio to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Santa Fe

What is the cheapest month to book a flight from Ohio to Santa Fe?

Currently, July is the cheapest month in which you can book a flight from Ohio to Santa Fe (average of $191). Flying from Ohio to Santa Fe in April is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from Ohio?

    For a flight from Ohio to Santa Fe, you will be flying into Santa Fe. Santa Fe (SAF) is just 9.8 mi from the center of the city.

  • How long is the flight from Ohio to Santa Fe?

    Departing from Ohio to Santa Fe will take you 5h 33m. Airlines will cover a distance of 1299 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Ohio to Santa Fe?

    Most travelers choose Detroit Metropolitan Wayne County - Santa Fe, Cincinnati Cinci./N. Kentucky - Santa Fe or Cleveland Hopkins Intl - Santa Fe when deciding on the best route from Ohio to Santa Fe.

  • Can I find deals for flights from Ohio to Santa Fe that include hotel bookings?

    Yes. In addition to deals on Ohio to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Santa Fe.

  • Can I find deals for business class flights from Ohio to Santa Fe?

    Yes. Cheapflights offers flight deals from Ohio to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Santa Fe?

    Currently, July is the cheapest month in which you can book a flight from Ohio to Santa Fe (average of $191). Flying from Ohio to Santa Fe in April is currently the most expensive (average of $287). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Alternative routes for Ohio to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Ohio to Santa Fe

Discover the top 2 airlines that operate flights from Ohio to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$234Average$518FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$253Average$395FlexibilityNo cancel feeOn-time71%

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