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$274+ Cheap flights from North Carolina to Santa Fe (SAF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SAF
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from North Carolina to Santa Fe

Keep the following information in mind while searching for North Carolina to Santa Fe flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$264
(American Airlines)

Popular in

June

Cheapest in

October

Average price

$512
Provider with most accurate pricing for Raleigh-Durham-Santa Fe flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Santa Fe flights.
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From North Carolina to Santa Fe
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Highest demand for flights based on searches. 12% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from North Carolina to Santa Fe

Cheapest flights from North Carolina to Santa Fe
Explore the most affordable flight options available from North Carolina to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:24 amTYS - SAF
1 stop6h 04mAmerican Airlines
Sat 12/136:15 amSAF - TYS
1 stop7h 17mAmerican Airlines
Deal found 11/24$334
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:05 amTYS - SAF
2 stops9h 34mUnited Airlines
Sat 12/133:20 pmSAF - TYS
1 stop5h 10mUnited Airlines
Deal found 11/24$340
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:37 pmRDU - SAF
1 stop8h 17mAmerican Airlines
Mon 12/159:58 amSAF - RDU
1 stop8h 31mAmerican Airlines
Deal found 11/26$354
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:30 amGSO - SAF
1 stop7h 54mAmerican Airlines
Mon 12/221:30 pmSAF - GSO
1 stop5h 52mAmerican Airlines
Deal found 11/26$364
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/48:15 amCLT - SAF
1 stop6h 22mUnited Airlines
Fri 12/121:20 pmSAF - CLT
1 stop7h 36mUnited Airlines
Deal found 11/24$369
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:00 amAVL - SAF
1 stop7h 46mAmerican Airlines
Sat 12/136:15 amSAF - AVL
1 stop7h 19mAmerican Airlines
Deal found 11/23$410
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:15 amCLT - SAF
1 stop8h 24mUnited Airlines
Sun 12/147:00 amSAF - CLT
1 stop6h 18mUnited Airlines
Deal found 11/24$414
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:10 amCLT - SAF
1 stop6h 25mAmerican Airlines
Thu 1/14:43 pmSAF - CLT
1 stop5h 32mAmerican Airlines
Deal found 11/26$428
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:04 amORF - SAF
1 stop6h 33mUnited Airlines
Sat 12/133:20 pmSAF - ORF
1 stop5h 39mUnited Airlines
Deal found 11/23$444
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:04 pmCLT - SAF
1 stop6h 36mAmerican Airlines
Mon 12/1512:36 pmSAF - CLT
1 stop8h 01mAmerican Airlines
Deal found 11/25$463
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:04 amORF - SAF
1 stop8h 35mUnited Airlines
Tue 12/91:20 pmSAF - ORF
1 stop7h 39mUnited Airlines
Deal found 11/24$489
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:15 amCLT - SAF
1 stop6h 22mUnited Airlines
Mon 12/151:20 pmSAF - CLT
2 stops8h 39mUnited Airlines
Deal found 11/25$493

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from North Carolina to Santa Fe that are best for you.

Fly from

North Carolina

Fly to

Santa Fe

Route

Depart

Return

Price

AshevilleSanta Fe

AVL - SAF

AVLSAF

Asheville Regional

Wed 1/21

1:54 pm-9:09 pm

2 stops9h 15m

Santa Fe

Wed 1/28

6:25 am-3:55 pm

1 stop7h 30m

$274

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 1/29

5:10 am-9:57 am

1 stop6h 47m

Santa Fe

Thu 2/5

3:23 pm-11:34 pm

1 stop6h 11m

$284

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

Tue 12/9

5:24 am-9:28 am

1 stop6h 04m

Santa Fe

Sat 12/13

6:15 am-3:32 pm

1 stop7h 17m

$334

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

Tue 12/9

7:05 am-2:39 pm

2 stops9h 34m

Santa Fe

Sat 12/13

3:20 pm-10:30 pm

1 stop5h 10m

$340

AshevilleSanta Fe

AVL - SAF

AVLSAF

Asheville Regional

Fri 1/23

7:50 am-12:29 pm

1 stop6h 39m

Santa Fe

Tue 1/27

12:59 pm-10:23 pm

1 stop7h 24m

$344

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

Sat 1/10

12:21 pm-4:48 pm

1 stop6h 27m

Santa Fe

Wed 1/14

12:59 pm-10:47 pm

1 stop7h 48m

$344

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Wed 1/7

7:45 am-2:53 pm

1 stop9h 08m

Santa Fe

Sat 1/10

5:18 pm-12:40 am

1 stop5h 22m

$344

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

Wed 1/7

8:00 am-2:54 pm

1 stop8h 54m

Santa Fe

Sat 1/10

7:00 am-5:24 pm

2 stops8h 24m

$354

RaleighSanta Fe

RDU - SAF

RDUSAF

Raleigh-Durham

Thu 12/11

3:37 pm-9:54 pm

1 stop8h 17m

Santa Fe

Mon 12/15

9:58 am-8:29 pm

1 stop8h 31m

$354

AshevilleSanta Fe

AVL - SAF

AVLSAF

Asheville Regional

Fri 1/23

7:50 am-12:29 pm

1 stop6h 39m

Santa Fe

Sat 1/31

6:25 am-5:33 pm

2 stops9h 08m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/26

Showing 1-10 of 40 results
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Best time to book a flight from North Carolina to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santa Fe

What is the cheapest month to book a flight from North Carolina to Santa Fe?

Currently, April is the cheapest month in which you can book a flight from North Carolina to Santa Fe (average of $138). Flying from North Carolina to Santa Fe in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to SAF?

Find hourly flight availability from North Carolina to Santa Fe. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

It’s typically best to fly out from North Carolina to Santa Fe in the afternoon. Doing so could potentially save you 27% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from North Carolina?

    If you book a flight to Santa Fe from North Carolina, you will be flying to Santa Fe, which is the city’s only airport. Santa Fe (SAF) is located 9.8 mi from the center of Santa Fe.

  • How long is the flight from North Carolina to Santa Fe?

    For as low as $274, American Airlines can have you in Santa Fe from North Carolina in 9h 15m. The distance from North Carolina to Santa Fe is about 1320 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from North Carolina to Santa Fe?

    While some choose either Greensboro/H. Point - Santa Fe or Charlotte Douglas - Santa Fe, Raleigh-Durham - Santa Fe is the most popular route from North Carolina to Santa Fe.

  • Can I find deals for flights from North Carolina to Santa Fe that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santa Fe.

  • Can I find deals for business class flights from North Carolina to Santa Fe?

    Yes. Cheapflights offers flight deals from North Carolina to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santa Fe?

    Currently, April is the cheapest month in which you can book a flight from North Carolina to Santa Fe (average of $138). Flying from North Carolina to Santa Fe in January is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

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Alternative routes for North Carolina to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from North Carolina to Santa Fe

Discover the top 2 airlines that operate flights from North Carolina to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$264Average$490FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$284Average$408FlexibilityNo cancel feeOn-time69%

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