HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Fe

$202+ Cheap flights from North Carolina to Santa Fe (SAF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SAF
feb. 19 — feb. 261
jue. 2/19
jue. 2/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from North Carolina to Santa Fe with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from North Carolina to Santa Fe

Cheapest flights from North Carolina to Santa Fe
Explore the most affordable flight options available from North Carolina to Santa Fe. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 20, 2026.

This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/265:40 am
TYS
-
SAF
1 stop5h 59m
American Airlines
lun. 3/24:15 pm
SAF
-
TYS
1 stop6h 13m
American Airlines
Deal found 1/18$233
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/34:41 pm
TYS
-
SAF
1 stop6h 28m
American Airlines
mié. 2/1112:59 pm
SAF
-
TYS
1 stop7h 48m
American Airlines
Deal found 1/19$284
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/205:15 am
CLT
-
SAF
1 stop6h 24m
American Airlines
jue. 2/266:42 pm
SAF
-
CLT
1 stop9h 14m
American Airlines
Deal found 1/20$285
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/275:23 am
RDU
-
SAF
1 stop6h 32m
American Airlines
sáb. 5/305:52 pm
SAF
-
RDU
1 stop10h 51m
American Airlines
Deal found 1/20$305
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/36:00 am
TYS
-
SAF
1 stop8h 29m
American Airlines
vie. 2/134:15 pm
SAF
-
TYS
1 stop5h 40m
American Airlines
Deal found 1/19$310
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/34:25 pm
TYS
-
SAF
1 stop6h 22m
United Airlines
mar. 2/107:00 am
SAF
-
TYS
1 stop6h 14m
United Airlines
Deal found 1/19$312
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/222:50 pm
RDU
-
SAF
2 stops9h 11m
United Airlines
vie. 8/281:26 pm
SAF
-
RDU
1 stop7h 39m
United Airlines
Deal found 1/20$314
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/2810:20 am
RDU
-
SAF
1 stop8h 46m
United Airlines
mar. 8/41:26 pm
SAF
-
RDU
1 stop7h 39m
United Airlines
Deal found 1/19$323
This American Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/35:30 am
TRI
-
SAF
1 stop8h 54m
American Airlines
mar. 3/1012:54 pm
SAF
-
TRI
1 stop7h 32m
American Airlines
Deal found 1/18$331
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/34:44 pm
AVL
-
SAF
1 stop6h 25m
American Airlines
sáb. 2/76:25 am
SAF
-
AVL
1 stop7h 26m
American Airlines
Deal found 1/19$335
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/37:05 am
GSO
-
SAF
1 stop7h 24m
American Airlines
sáb. 2/76:25 am
SAF
-
GSO
1 stop8h 24m
American Airlines
Deal found 1/19$335
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/34:07 pm
RDU
-
SAF
1 stop6h 40m
United Airlines
sáb. 2/73:30 pm
SAF
-
RDU
1 stop5h 45m
United Airlines
Deal found 1/19$355

Find flight deals from North Carolina to Santa Fe

Keep the following information in mind while searching for North Carolina to Santa Fe flight deals. Data was last updated enero 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$233
(American Airlines)

One-way from

$202
(American Airlines)

Popular in

June

Cheapest in

January

Average price

$334
Provider with most accurate pricing for Raleigh-Durham-Santa Fe flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Santa Fe flights.
Search Deals
From North Carolina to Santa Fe
Search Deals
One-way flight from North Carolina to Santa Fe
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to Santa Fe that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 20, 2026.
Use the filters below to find and compare flights from North Carolina to Santa Fe that are best for you.

Fly from

North Carolina

Fly to

Santa Fe

Route

Depart

Return

Price

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

jue. 2/26

5:40 am-9:39 am

1 stop5h 59m

Santa Fe

lun. 3/2

4:15 pm-12:28 am

1 stop6h 13m

$259

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

mar. 2/3

4:41 pm-9:09 pm

1 stop6h 28m

Santa Fe

mié. 2/11

12:59 pm-10:47 pm

1 stop7h 48m

$284

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

vie. 2/20

5:15 am-9:39 am

1 stop6h 24m

Santa Fe

jue. 2/26

6:42 pm-5:56 am

1 stop9h 14m

$285

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

mar. 2/3

4:25 pm-8:47 pm

1 stop6h 22m

Santa Fe

mar. 2/10

7:00 am-3:14 pm

1 stop6h 14m

$312

KnoxvilleSanta Fe

TYS - SAF

TYSSAF

Knoxville McGhee Tyson

mar. 2/3

6:59 am-4:56 pm

2 stops11h 57m

Santa Fe

mié. 2/11

10:45 am-8:52 pm

2 stops8h 07m

$327

BlountvilleSanta Fe

TRI - SAF

TRISAF

Blountville Tri Cities TN/VA

mar. 3/3

5:30 am-12:24 pm

1 stop8h 54m

Santa Fe

mar. 3/10

12:54 pm-10:26 pm

1 stop7h 32m

$331

AshevilleSanta Fe

AVL - SAF

AVLSAF

Asheville Regional

mar. 2/3

4:44 pm-9:09 pm

1 stop6h 25m

Santa Fe

sáb. 2/7

6:25 am-3:51 pm

1 stop7h 26m

$335

GreensboroSanta Fe

GSO - SAF

GSOSAF

Greensboro/H. Point

mar. 2/3

6:00 am-4:35 pm

2 stops12h 35m

Santa Fe

sáb. 2/7

6:25 am-4:49 pm

1 stop8h 24m

$344

CharlotteSanta Fe

CLT - SAF

CLTSAF

Charlotte Douglas

mar. 4/21

8:06 am-2:48 pm

1 stop8h 42m

Santa Fe

mar. 4/28

1:19 pm-10:59 pm

1 stop7h 40m

$357

GreensboroSanta Fe

GSO - SAF

GSOSAF

Greensboro/H. Point

sáb. 4/25

4:48 pm-9:07 pm

1 stop6h 19m

Santa Fe

lun. 5/11

2:04 pm-10:47 pm

1 stop6h 43m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 40 results
1
2
3
4

Best time to book a flight from North Carolina to Santa Fe

Have a flexible travel schedule? Discover the best time to fly to Santa Fe from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Santa Fe

What is the cheapest month to book a flight from North Carolina to Santa Fe?

Currently, April is the cheapest month in which you can book a flight from North Carolina to Santa Fe (average of $138). Flying from North Carolina to Santa Fe in November is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from North Carolina to Santa Fe?

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Santa Fe. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Fe from North Carolina?

    If you book a flight to Santa Fe from North Carolina, you will be flying to Santa Fe, which is the city’s only airport. Santa Fe (SAF) is located 9.8 mi from the center of Santa Fe.

  • How long is the flight from North Carolina to Santa Fe?

    For as low as $259, American Airlines can have you in Santa Fe from North Carolina in 5h 59m. The distance from North Carolina to Santa Fe is about 1236 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from North Carolina to Santa Fe?

    While some choose either Charlotte Douglas - Santa Fe or Knoxville McGhee Tyson - Santa Fe, Raleigh-Durham - Santa Fe is the most popular route from North Carolina to Santa Fe.

  • Can I find deals for flights from North Carolina to Santa Fe that include hotel bookings?

    Yes. In addition to deals on North Carolina to Santa Fe flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Santa Fe?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Santa Fe.

  • Can I find deals for business class flights from North Carolina to Santa Fe?

    Yes. Cheapflights offers flight deals from North Carolina to Santa Fe by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Santa Fe?

    Currently, April is the cheapest month in which you can book a flight from North Carolina to Santa Fe (average of $138). Flying from North Carolina to Santa Fe in November is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santa Fe?

Book flights to Santa Fe if you plan to visit one of these locations
Santa Rosa

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for North Carolina to Santa Fe

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Albuquerque flights
Seattle to Albuquerque flights
Dulles Intl to Albuquerque flights
Baltimore to Albuquerque flights
Dallas/Fort Worth to El Paso flights
San Francisco to Albuquerque flights
John F Kennedy Intl to Albuquerque flights
Newark to Albuquerque flights
LaGuardia to Albuquerque flights
Boston to Albuquerque flights
Atlanta to Albuquerque flights
Los Angeles to Albuquerque flights
O'Hare Intl to El Paso flights
Newark to Santa Fe flights
Austin to Albuquerque flights
Reagan-National to Albuquerque flights
Los Angeles to El Paso flights
LaGuardia to Santa Fe flights
Minneapolis to Albuquerque flights
Hobby to El Paso flights
Dallas/Fort Worth to Albuquerque flights
O'Hare Intl to Santa Fe flights
San Francisco to Santa Fe flights
Austin to El Paso flights
George Bush Intcntl to El Paso flights
Love Field to El Paso flights
Denver to El Paso flights
Boston to Santa Fe flights
Ontario to El Paso flights
John F Kennedy Intl to Santa Fe flights
Ontario to Albuquerque flights
Dallas/Fort Worth to Santa Fe flights
Los Angeles to Santa Fe flights
Seattle to Santa Fe flights
John F Kennedy Intl to El Paso flights
Atlanta to El Paso flights
Midway to Albuquerque flights
Denver to Albuquerque flights
Portland to Albuquerque flights
Philadelphia to Albuquerque flights
Sky Harbor Intl to Albuquerque flights
San Diego to Albuquerque flights
LaGuardia to El Paso flights
Hobby to Albuquerque flights
Minneapolis to Santa Fe flights
Austin to Santa Fe flights
Newark to El Paso flights
Raleigh to Santa Fe flights
Baltimore to Santa Fe flights
Dulles Intl to Santa Fe flights

Top 2 airlines flying from North Carolina to Santa Fe

Discover the top 2 airlines that operate flights from North Carolina to Santa Fe. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$264Average$488FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$284Average$374FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.