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Santa Cruz de la Sierra

$180+ Cheap flights from Santiago (SCL) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — VVI
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Santiago to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$391
(Trip.com)

One-way from

$180
(KAYAK)

Popular in

February

Cheapest in

May

Average price

$421
From Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 5% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santiago to Santa Cruz de la Sierra

Cheapest flights from Santiago to Santa Cruz de la Sierra
Explore the most affordable flight options available from Santiago to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/201:10 pmSCL - VVI
Nonstop3h 15mBoA
Mon 10/278:00 amVVI - SCL
Nonstop3h 15mBoA
Deal found 9/14$391
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:15 amSCL - VVI
1 stop15h 55mAerolineas Argentinas
Fri 10/312:00 amVVI - SCL
1 stop18h 00mAerolineas Argentinas
Deal found 9/14$406
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:50 pmSCL - VVI
1 stop8h 45mLATAM Airlines
Sat 11/111:15 amVVI - SCL
Nonstop3h 02mLATAM Airlines
Deal found 9/14$408
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:00 pmSCL - VVI
1 stop14h 35mLATAM Airlines
Sun 1/45:25 amVVI - SCL
1 stop7h 40mLATAM Airlines
Deal found 9/14$453
This OneTravel deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2810:30 amSCL - VVI
2 stops19h 05mLATAM Airlines
Tue 12/25:25 amVVI - SCL
1 stop17h 00mLATAM Airlines
Deal found 9/15$458
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:15 amSCL - VVI
1 stop24h 20mLATAM Airlines
Wed 12/107:26 amVVI - SCL
Nonstop3h 02mLATAM Airlines
Deal found 9/15$469
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:30 pmSCL - VVI
1 stop11h 05mLATAM Airlines
Sun 1/45:25 amVVI - SCL
1 stop7h 40mLATAM Airlines
Deal found 9/14$472
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:50 pmSCL - VVI
1 stop8h 45mLATAM Airlines
Sun 1/45:25 amVVI - SCL
1 stop7h 40mLATAM Airlines
Deal found 9/14$491
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/271:10 pmSCL - VVI
Nonstop3h 15mBoA
Sat 11/18:00 amVVI - SCL
Nonstop3h 15mBoA
Deal found 9/14$494
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/201:10 pmSCL - VVI
Nonstop3h 15mMultiple Airlines
Mon 10/2710:00 amVVI - SCL
1 stop12h 55mMultiple Airlines
Deal found 9/14$502

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Santiago to Santa Cruz de la Sierra that are best for you.

Fly from

Santiago

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 10/27

10:15 am-1:10 am

1 stop15h 55m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/31

2:00 am-9:00 pm

1 stop18h 00m

$406

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 10/27

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/1

11:15 am-3:17 pm

Nonstop3h 02m

$408

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 10/27

3:00 pm-4:35 am

1 stop14h 35m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/31

5:25 am-2:05 pm

1 stop7h 40m

$411

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Fri 11/28

10:30 am-4:35 am

2 stops19h 05m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/2

5:25 am-11:25 pm

1 stop17h 00m

$458

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 11/27

5:15 am-4:35 am

1 stop24h 20m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/10

7:26 am-11:28 am

Nonstop3h 02m

$469

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 12/25

6:30 pm-4:35 am

1 stop11h 05m

Santa Cruz de la Sierra Viru Viru Intl

Sun 1/4

5:25 am-2:05 pm

1 stop7h 40m

$472

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 10/27

1:10 pm-3:25 pm

Nonstop3h 15m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/1

8:00 am-12:15 pm

Nonstop3h 15m

$494

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sun 1/18

6:00 am-9:56 am

1 stop4h 56m

$180

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 1/17

6:30 pm-4:35 am

1 stop11h 05m

$185

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Fri 1/9

1:40 pm-4:35 am

1 stop15h 55m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 11 results
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Best time to book a flight from Santiago to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santa Cruz de la Sierra

How far ahead should I book a flight from Santiago to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santa Cruz de la Sierra. Price data was last updated on September 12, 2025.

The best time to book flights from Santiago to Santa Cruz de la Sierra is 77 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $597). Flying from Santiago to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to VVI?

Find hourly flight availability from Santiago to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

A simple way to save on the total cost of your ticket is to fly from Santiago to Santa Cruz de la Sierra at noon. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated September 15, 2025.
See what other customers who have flown with LATAM Airlines from Santiago to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,847 reviews

Comfort

7.4

Overall

7.5

Food

6.7

Boarding

7.6

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
LATAM Airlines
7.5
Good
1,847 reviews
LATAM Airlines
7.5
Good
1,847 reviews

Comfort

7.4

Overall

7.5

Food

6.7

Boarding

7.6

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Santa Cruz de la Sierra?

    Aerolineas Argentinas and LATAM Airlines can get you from Santiago to Santa Cruz de la Sierra in just under 8h 45m. Your travel time can differ by up to 7h 10m. There are 1186 mi between Santiago and Santa Cruz de la Sierra. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Santiago to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Santiago to Santa Cruz de la Sierra is LATAM Airlines. Our recent data shows that you can find tickets from as low as $286 on this airline. LATAM Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santiago to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Santiago to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Santiago to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Santiago to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $597). Flying from Santiago to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to La Paz flights

Top airline flying from Santiago to Santa Cruz de la Sierra

Discover the top airline that operate flights from Santiago to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time81%

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