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Santa Cruz de la Sierra

$125+ Cheap flights from Santiago (SCL) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — VVI
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Santiago to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$303
(Kiwi.com)

One-way from

$125
(Booking.com)

Popular in

February

Cheapest in

May

Average price

$399
From Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santiago to Santa Cruz de la Sierra

Cheapest flights from Santiago to Santa Cruz de la Sierra
Explore the most affordable flight options available from Santiago to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:10 amSCL - VVI
1 stop21h 25mLATAM Airlines
Sat 8/3011:16 amVVI - SCL
Nonstop3h 09mLATAM Airlines
Deal found 7/29$303
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/253:55 pmSCL - VVI
1 stop9h 10mAerolineas Argentinas
Fri 8/292:00 amVVI - SCL
1 stop14h 50mAerolineas Argentinas
Deal found 7/29$319
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:45 pmSCL - VVI
1 stop8h 50mMultiple Airlines
Fri 8/292:00 amVVI - SCL
1 stop14h 50mMultiple Airlines
Deal found 7/29$395
This Avianca deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:55 amSCL - VVI
1 stop20h 05mAvianca
Sat 1/33:05 amVVI - SCL
1 stop25h 05mAvianca
Deal found 7/30$1,810

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Santiago to Santa Cruz de la Sierra that are best for you.

Fly from

Santiago

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 8/28

7:10 am-4:35 am

1 stop21h 25m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/30

11:16 am-2:25 pm

Nonstop3h 09m

$303

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 8/25

3:55 pm-1:05 am

1 stop9h 10m

Santa Cruz de la Sierra Viru Viru Intl

Fri 8/29

2:00 am-4:50 pm

1 stop14h 50m

$319

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Wed 8/27

7:45 pm-4:35 am

1 stop8h 50m

Santa Cruz de la Sierra Viru Viru Intl

Fri 8/29

2:00 am-4:50 pm

1 stop14h 50m

$395

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 12/25

6:55 am-2:00 am

1 stop20h 05m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/3

3:05 am-5:10 am

1 stop25h 05m

$1,810

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Wed 8/27

4:31 am-7:41 am

Nonstop3h 10m

$125

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Fri 8/29

9:25 am-1:05 am

1 stop15h 40m

$173

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Tue 8/26

12:40 am-11:05 am

1 stop10h 25m

$248

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Santiago to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santa Cruz de la Sierra

How far ahead should I book a flight from Santiago to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santa Cruz de la Sierra. Price data was last updated on July 25, 2025.

The best time to book flights from Santiago to Santa Cruz de la Sierra is 65 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $597). Flying from Santiago to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to VVI?

Find hourly flight availability from Santiago to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

A simple way to save on the total cost of your ticket is to fly from Santiago to Santa Cruz de la Sierra at noon. If you’re flexible enough to do this you can expect to save up to 19% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Santiago to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated July 31, 2025.
See what other customers who have flown with Aerolineas Argentinas, LATAM Airlines, and Avianca from Santiago to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.1
Very good
899 reviews

Comfort

7.5

Boarding

8.0

Food

6.4

Crew

8.3

Overall

8.1

Entertainment

5.7

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Aerolineas Argentinas
8.1
Very good
899 reviews
Aerolineas Argentinas
8.1
Very good
899 reviews

Comfort

7.5

Boarding

8.0

Food

6.4

Crew

8.3

Overall

8.1

Entertainment

5.7

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
LATAM Airlines
7.5
Good
1,822 reviews
Aerolineas Argentinas
8.1
Very good
899 reviews

Comfort

7.5

Boarding

8.0

Food

6.4

Crew

8.3

Overall

8.1

Entertainment

5.7

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.
Avianca
6.7
Okay
2,388 reviews
Aerolineas Argentinas
8.1
Very good
899 reviews

Comfort

7.5

Boarding

8.0

Food

6.4

Crew

8.3

Overall

8.1

Entertainment

5.7

Reviews

1 / 4
10.0
Excellent

Firuz,Dec 2024

EZE - SLA

Great airline on time and friendly staff. Check-in and boarding even at EZE was easy and straight forward and fast.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Santiago to Santa Cruz de la Sierra is LATAM Airlines. Our recent data shows that you can find tickets from as low as $303 on this airline. Additional options worth looking into are Aerolineas Argentinas and Avianca, starting at $319 and $1,810 round-trip. LATAM Airlines is 23% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santiago to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Santiago to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Santiago to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Santiago to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $597). Flying from Santiago to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Santiago to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to La Paz flights

Top airline flying from Santiago to Santa Cruz de la Sierra

Discover the top airline that operate flights from Santiago to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$286Average$495FlexibilityNo cancel feeOn-time81%

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