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Santa Cruz de la Sierra

$263+ Cheap flights from Santiago (SCL) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — VVI
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Santiago to Santa Cruz de la Sierra

Cheapest flights from Santiago to Santa Cruz de la Sierra
Explore the most affordable flight options available from Santiago to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:39 pmSCL - VVI
2 stops32h 56mLATAM Airlines
Wed 12/317:26 amVVI - SCL
Nonstop3h 02mLATAM Airlines
Deal found 12/17$635
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:35 pmSCL - VVI
2 stops25h 05mMultiple Airlines
Wed 12/315:25 amVVI - SCL
1 stop9h 05mMultiple Airlines
Deal found 12/17$725
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:25 amSCL - VVI
1 stop20h 10mAvianca
Wed 12/313:40 amVVI - SCL
1 stop19h 50mAvianca
Deal found 12/16$732
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:32 amSCL - VVI
1 stop4h 56mLATAM Airlines
Tue 12/235:25 amVVI - SCL
1 stop24h 00mLATAM Airlines
Deal found 12/17$741
This OneTravel deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:32 amSCL - VVI
Nonstop4h 56mLATAM Airlines
Mon 12/225:25 amVVI - SCL
1 stop9h 05mLATAM Airlines
Deal found 12/17$772
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:50 pmSCL - VVI
2 stops18h 50mMultiple Airlines
Thu 1/19:05 amVVI - SCL
1 stop14h 05mMultiple Airlines
Deal found 12/16$788
This CheapOair deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:32 amSCL - VVI
Nonstop4h 56mLATAM Airlines
Sat 12/275:25 amVVI - SCL
1 stop17h 00mLATAM Airlines
Deal found 12/17$864

Find flight deals from Santiago to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

OneTravel
3 stars

Most trusted provider

OneTravel
3 stars

Round-trip from

$395
(Mytrip)

One-way from

$263
(Avianca)

Popular in

December

Cheapest in

October

Average price

$459
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Santa Cruz de la Sierra Viru Viru Intl flights.
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From Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Santiago to Santa Cruz de la Sierra that are best for you.

Fly from

Santiago

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 3/12

4:35 am-4:35 am

1 stop25h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/15

10:43 am-2:45 pm

Nonstop3h 02m

$395

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 1/31

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/7

11:15 am-3:17 pm

Nonstop3h 02m

$500

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 1/19

5:15 am-4:35 am

1 stop24h 20m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/24

11:15 am-3:17 pm

Nonstop3h 02m

$511

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 1/31

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/21

5:25 am-5:25 pm

1 stop11h 00m

$584

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 1/3

6:32 am-10:28 am

Nonstop4h 56m

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/10

9:50 pm-2:05 pm

2 stops15h 15m

$610

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 12/29

4:25 pm-2:35 am

1 stop11h 10m

$263

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 12/25

2:57 pm-4:35 am

1 stop14h 38m

$298

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 12/25

5:12 am-4:35 am

2 stops24h 23m

$332

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 12/29

1:10 pm-3:25 pm

Nonstop3h 15m

$473

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 12/29

3:45 pm-4:35 am

2 stops13h 50m

$480

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 13 results
1
2

Compare providers for flights from Santiago to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Santa Cruz de la Sierra in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
OneTravelPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-Santa Cruz de la Sierra flights, users find the pricing of OneTravel to be most consistent on Cheapflights vs. OneTravel Users can find the same prices on Santiago-Santa Cruz de la Sierra flight deals on Cheapflights vs. OneTravel >95% of the time. Price accuracy is based on data collected from Santiago-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Santa Cruz de la Sierra flights, Cheapflights users trust OneTravel the most. OneTravel has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santa Cruz de la Sierra

How far ahead should I book a flight from Santiago to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santa Cruz de la Sierra. Price data was last updated on December 12, 2025.

The best time to book flights from Santiago to Santa Cruz de la Sierra is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

Currently, August is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $188). Flying from Santiago to Santa Cruz de la Sierra in January is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to VVI?

Find hourly flight availability from Santiago to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Santiago to Santa Cruz de la Sierra in the morning. If you’re flexible enough to do this you can expect to save up to 49% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated December 18, 2025.
See what other customers who have flown with LATAM Airlines from Santiago to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,893 reviews

Entertainment

7.0

Crew

8.0

Overall

7.5

Boarding

7.6

Food

6.7

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.
LATAM Airlines
7.5
Good
1,893 reviews
LATAM Airlines
7.5
Good
1,893 reviews

Entertainment

7.0

Crew

8.0

Overall

7.5

Boarding

7.6

Food

6.7

Comfort

7.3

Reviews

1 / 20
8.0
Excellent

Darrel,Sep 2025

LIM - GRU

The Wi-Fi was not working, so there was no in-flight entertainment. The biggest disappointment was that my Delta diamond status did not transfer any status to my LATAM flight. I WOULD’VE THOUGHT THAT THERE WOULD BE A BETTER WORKING AGREEMENT BETWEEN THE AIRLINES.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Santa Cruz de la Sierra flight route?

    The Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Santa Cruz de la Sierra?

    LATAM Airlines can get you from Santiago to Santa Cruz de la Sierra in just under 25h. Your travel time can differ by up to . There are 1186 mi between Santiago and Santa Cruz de la Sierra.

  • What is the cheapest airline to fly from Santiago to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Santiago to Santa Cruz de la Sierra is LATAM Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. LATAM Airlines is 39% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $186. While the most popular route (Santiago Arturo Merino Benitez - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $471 on average, our data indicates $346 when flying from Santiago to Santa Cruz de la Sierra.

  • Can I find deals for flights from Santiago to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Santiago to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Santiago to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Santiago to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

    Currently, August is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $188). Flying from Santiago to Santa Cruz de la Sierra in January is currently the most expensive (average of $338). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santiago to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to La Paz flights

Top airline flying from Santiago to Santa Cruz de la Sierra

Discover the top airline that operate flights from Santiago to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$248Average$394FlexibilityNo cancel feeOn-time81%

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