HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$214+ Cheap flights from Santiago (SCL) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — VVI
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santiago to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Santiago to Santa Cruz de la Sierra

Cheapest flights from Santiago to Santa Cruz de la Sierra
Explore the most affordable flight options available from Santiago to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:50 pm
SCL
-
VVI
1 stop8h 45m
LATAM Airlines
Sun 3/810:41 am
VVI
-
SCL
Nonstop3h 04m
LATAM Airlines
Deal found 2/1$411
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:10 pm
SCL
-
VVI
Nonstop3h 15m
Multiple Airlines
Fri 5/222:20 am
VVI
-
SCL
1 stop11h 25m
Multiple Airlines
Deal found 2/1$428
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:00 am
SCL
-
VVI
1 stop4h 56m
LATAM Airlines
Sun 3/85:25 am
VVI
-
SCL
2 stops13h 28m
LATAM Airlines
Deal found 2/2$450
This Booking.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:10 pm
SCL
-
VVI
Nonstop3h 15m
Multiple Airlines
Mon 3/99:40 am
VVI
-
SCL
1 stop10h 40m
Multiple Airlines
Deal found 2/2$514
This Travelocity deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:30 pm
SCL
-
VVI
1 stop11h 05m
LATAM Airlines
Mon 3/95:25 am
VVI
-
SCL
1 stop9h 05m
LATAM Airlines
Deal found 2/2$522
This CheapOair deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/174:50 pm
SCL
-
VVI
2 stops15h 20m
Multiple Airlines
Sat 5/235:25 am
VVI
-
SCL
1 stop8h 40m
Multiple Airlines
Deal found 2/1$525

Find flight deals from Santiago to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$411
(FlightHub)

One-way from

$214
(FlightHub)

Popular in

January

Cheapest in

October

Average price

$437
Provider with most accurate pricing for Santiago Arturo Merino Benitez-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Santiago to Santa Cruz de la Sierra that are best for you.

Fly from

Santiago

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Fri 3/6

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/8

10:41 am-2:45 pm

Nonstop3h 04m

$414

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 2/28

4:35 am-4:35 am

1 stop25h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sun 3/8

10:41 am-2:45 pm

Nonstop3h 04m

$459

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Mon 3/2

6:30 pm-4:35 am

1 stop11h 05m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

5:25 am-3:30 pm

1 stop9h 05m

$522

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 3/5

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

5:25 am-3:30 pm

1 stop9h 05m

$522

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Thu 3/5

8:50 pm-4:35 am

1 stop8h 45m

Santa Cruz de la Sierra Viru Viru Intl

Sun 4/5

5:20 pm-4:50 am

2 stops11h 30m

$543

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Tue 3/10

6:30 pm-4:35 am

1 stop11h 05m

Santa Cruz de la Sierra Viru Viru Intl

Sun 4/5

5:20 pm-3:25 am

2 stops10h 05m

$543

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Tue 4/14

6:40 am-2:30 am

1 stop19h 50m

$214

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Tue 4/14

7:45 pm-8:10 am

2 stops12h 25m

$266

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Wed 2/11

1:35 am-4:40 pm

1 stop16h 05m

$325

SantiagoSanta Cruz de la Sierra

SCL - VVI

SCLVVI

Santiago Arturo Merino Benitez

Sat 2/7

6:32 am-10:28 am

1 stop4h 56m

$350

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 11 results
1
2

Compare providers for flights from Santiago to Santa Cruz de la Sierra

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Santa Cruz de la Sierra in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OneTravelPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Santa Cruz de la Sierra

How far ahead should I book a flight from Santiago to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Santa Cruz de la Sierra. Price data was last updated on January 30, 2026.

The best time to book flights from Santiago to Santa Cruz de la Sierra is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

Currently, August is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $193). Flying from Santiago to Santa Cruz de la Sierra in January is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to VVI?

Find hourly flight availability from Santiago to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Santa Cruz de la Sierra as you normally would.

How much does it cost to fly round-trip from Santiago to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated February 3, 2026.
See what other customers who have flown with LATAM Airlines from Santiago to Santa Cruz de la Sierra have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Food

6.7

Overall

7.5

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.5
Good
1,918 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Food

6.7

Overall

7.5

Comfort

7.3

Crew

8.0

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Santiago to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Santa Cruz de la Sierra flight route?

    The Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Santa Cruz de la Sierra?

    LATAM Airlines can get you from Santiago to Santa Cruz de la Sierra in just under 8h 45m. Your travel time can differ by up to . There are 1186 mi between Santiago and Santa Cruz de la Sierra.

  • What is the cheapest airline to fly from Santiago to Santa Cruz de la Sierra round-trip?

    Our cheapest airline available from Santiago to Santa Cruz de la Sierra is LATAM Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. LATAM Airlines is 40% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Santiago to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Santiago to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Santiago to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Santiago to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Santa Cruz de la Sierra?

    Currently, August is the cheapest month in which you can book a flight from Santiago to Santa Cruz de la Sierra (average of $193). Flying from Santiago to Santa Cruz de la Sierra in January is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santiago to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to La Paz flights

Top airline flying from Santiago to Santa Cruz de la Sierra

Discover the top airline that operate flights from Santiago to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$248Average$416FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.