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Santa Cruz de la Sierra

$248+ Cheap flights from Mexico City (MEX) to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — VVI
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Mexico City Benito Juarez to Santa Cruz de la Sierra Viru Viru Intl are usually found in May or February, booked 57 days in advance, depart on a Sunday or Saturday and return on a Monday

Cheap flight deals from Mexico City to Santa Cruz de la Sierra

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$432
(Priceline)

One-way from

$248
(Avianca Connect)

Popular in

December

Cheapest in

May

Average price

$573
From Mexico City Benito Juarez to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Mexico City Benito Juarez to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Mexico City to Santa Cruz de la Sierra

Cheapest flights from Mexico City to Santa Cruz de la Sierra
Explore the most affordable flight options available from Mexico City to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Priceline deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/712:40 amMEX - VVI
1 stop23h 10mAvianca
Mon 7/282:55 amVVI - MEX
1 stop17h 10mAvianca
Deal found 6/10$432
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:40 amMEX - VVI
1 stop18h 45mCopa Airlines
Mon 9/812:15 pmVVI - MEX
1 stop11h 50mCopa Airlines
Deal found 6/10$493
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/293:10 pmMEX - VVI
1 stop11h 25mLATAM Airlines
Wed 8/205:20 amVVI - MEX
1 stop10h 30mLATAM Airlines
Deal found 6/12$530
This Priceline deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/255:55 pmMEX - VVI
2 stops32h 40mMultiple Airlines
Fri 8/15:20 amVVI - MEX
1 stop10h 30mMultiple Airlines
Deal found 6/10$738
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/162:15 pmMEX - VVI
2 stops29h 58mUnited Airlines
Thu 6/191:09 amVVI - MEX
2 stops24h 01mUnited Airlines
Deal found 6/10$4,019

Cheapflights Fare Finder

Customize your flight search to find flights from Mexico City to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Mexico City to Santa Cruz de la Sierra that are best for you.

Fly from

Mexico City

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Mexico CitySanta Cruz de la Sierra

MEX - VVI

MEXVVI

Mexico City Benito Juarez

Mon 7/7

12:40 am-1:50 am

1 stop23h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 7/28

2:55 am-6:05 pm

1 stop17h 10m

$432

Mexico CitySanta Cruz de la Sierra

MEX - VVI

MEXVVI

Mexico City Benito Juarez

Thu 9/4

1:40 am-10:25 pm

1 stop18h 45m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/8

12:15 pm-10:05 pm

1 stop11h 50m

$493

Mexico CitySanta Cruz de la Sierra

MEX - VVI

MEXVVI

Mexico City Benito Juarez

Tue 7/29

3:10 pm-4:35 am

1 stop11h 25m

Santa Cruz de la Sierra Viru Viru Intl

Wed 8/20

5:20 am-1:50 pm

1 stop10h 30m

$530

Mexico CitySanta Cruz de la Sierra

MEX - VVI

MEXVVI

Mexico City Benito Juarez

Fri 7/25

5:55 pm-4:35 am

2 stops32h 40m

Santa Cruz de la Sierra Viru Viru Intl

Fri 8/1

5:20 am-1:50 pm

1 stop10h 30m

$738

Mexico CitySanta Cruz de la Sierra

MEX - VVI

MEXVVI

Mexico City Benito Juarez

Fri 8/1

12:40 am-1:50 am

1 stop23h 10m

$248

Mexico CitySanta Cruz de la Sierra

MEX - VVI

MEXVVI

Mexico City Benito Juarez

Wed 7/9

2:00 am-10:19 pm

1 stop18h 19m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Best time to book a flight from Mexico City to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santa Cruz de la Sierra

How far ahead should I book a flight from Mexico City to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Santa Cruz de la Sierra. Price data was last updated on June 9, 2025.

The best time to book flights from Mexico City to Santa Cruz de la Sierra is 56 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mexico City to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Mexico City to Santa Cruz de la Sierra (average of $597). Flying from Mexico City to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to VVI?

Find hourly flight availability from Mexico City to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 41% on flights from Mexico City to Santa Cruz de la Sierra by exploring options for tickets at noon.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated June 12, 2025.
LATAM Airlines
7.5
Good
1,785 reviews

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

ATL - MSP

Late flight, just one person at the gate. He managed to solve problems and get everybody on the plane at the same time smoothly and with great professionalism. Left on time and arrived early to MSP
LATAM Airlines
7.5
Good
1,785 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

ATL - MSP

Late flight, just one person at the gate. He managed to solve problems and get everybody on the plane at the same time smoothly and with great professionalism. Left on time and arrived early to MSP
Copa Airlines
7.5
Good
1,451 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

ATL - MSP

Late flight, just one person at the gate. He managed to solve problems and get everybody on the plane at the same time smoothly and with great professionalism. Left on time and arrived early to MSP
Avianca
6.7
Okay
2,345 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Entertainment

7.0

Overall

7.5

Boarding

7.6

Food

6.7

Crew

8.1

Comfort

7.4

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2025

ATL - MSP

Late flight, just one person at the gate. He managed to solve problems and get everybody on the plane at the same time smoothly and with great professionalism. Left on time and arrived early to MSP

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Mexico City to Santa Cruz de la Sierra round-trip?

    Cheapflights users have booked flights from Mexico City to Santa Cruz de la Sierra round-trip from $432. Other airlines that can offer you cheap pricing are Copa Airlines, from $493, and LATAM Airlines, from $530. Avianca is currently priced 27% below the average price you’ll pay for this route.

  • Can I find deals for flights from Mexico City to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Mexico City to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Mexico City to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Mexico City to Santa Cruz de la Sierra (average of $597). Flying from Mexico City to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mexico City to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Mexico City to La Paz flights

Top 3 airlines flying from Mexico City to Santa Cruz de la Sierra

Discover the top 3 airlines that operate flights from Mexico City to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$473Average$532FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$512Average$935FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$558Average$746FlexibilityNo cancel feeOn-time70%

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