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Santa Cruz de la Sierra

$209+ Cheap flights from Key Largo, FL to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — VVI
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Santa Cruz de la Sierra Viru Viru Intl are usually found in April or March, booked 85 days in advance, depart on a Thursday or Tuesday and return on a Friday

Cheap flight deals from Key Largo to Santa Cruz de la Sierra

Keep the following information in mind while searching for Key Largo to Santa Cruz de la Sierra flight deals. Data was last updated April 30, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$466
(Avianca)

One-way from

$209
(Priceline)

Popular in

December

Cheapest in

April

Average price

$560
Provider with most accurate pricing for Miami-Santa Cruz de la Sierra Viru Viru Intl flight deals.
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Provider most trusted by Cheapflights users for Miami-Santa Cruz de la Sierra Viru Viru Intl flights.
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From Key Largo to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Key Largo to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 7% potential increase in price ($48 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Key Largo to Santa Cruz de la Sierra

Cheapest flights from Key Largo to Santa Cruz de la Sierra
Explore the most affordable flight options available from Key Largo to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Avianca deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:00 pmMIA - VVI
1 stop8h 50mAvianca
Mon 5/192:55 amVVI - MIA
1 stop15h 00mAvianca
Deal found 4/29$466
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:21 pmMIA - VVI
1 stop10h 17mCopa Airlines
Sat 10/2512:15 pmVVI - MIA
1 stop10h 12mCopa Airlines
Deal found 4/29$469
This eDestinos deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:00 pmMIA - VVI
Nonstop6h 50mBoA
Fri 10/318:35 amVVI - MIA
Nonstop6h 50mBoA
Deal found 4/29$505
This Justfly.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/278:12 amMIA - VVI
2 stops20h 23mLATAM Airlines
Mon 8/45:20 amVVI - MIA
1 stop9h 55mLATAM Airlines
Deal found 4/29$542
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:25 amMIA - VVI
2 stops15h 48mUnited Airlines
Tue 5/201:09 amVVI - MIA
2 stops19h 25mUnited Airlines
Deal found 4/29$575
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:20 pmMIA - VVI
1 stop30h 30mMultiple Airlines
Mon 5/2611:35 pmVVI - MIA
Nonstop6h 50mMultiple Airlines
Deal found 4/29$586
This eDestinos deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:00 pmMIA - VVI
2 stops37h 35mGOL
Fri 10/3112:25 pmVVI - MIA
2 stops28h 10mGOL
Deal found 4/29$646

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Key Largo to Santa Cruz de la Sierra that are best for you.

Fly from

Key Largo

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Tue 5/13

5:00 pm-1:50 am

1 stop8h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/19

2:55 am-5:55 pm

1 stop15h 00m

$466

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Fri 10/17

5:21 pm-3:38 am

1 stop10h 17m

Santa Cruz de la Sierra Viru Viru Intl

Sat 10/25

12:15 pm-10:27 pm

1 stop10h 12m

$469

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 10/13

10:00 pm-4:50 am

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/31

8:35 am-3:25 pm

Nonstop6h 50m

$505

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Sun 7/27

8:12 am-4:35 am

2 stops20h 23m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/4

5:20 am-3:15 pm

1 stop9h 55m

$542

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Tue 5/13

6:25 am-10:13 pm

2 stops15h 48m

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/20

1:09 am-8:34 pm

2 stops19h 25m

$575

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Thu 5/22

7:20 pm-1:50 am

1 stop30h 30m

Santa Cruz de la Sierra Viru Viru Intl

Mon 5/26

11:35 pm-6:25 am

Nonstop6h 50m

$586

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 10/13

10:00 pm-11:35 am

2 stops37h 35m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/31

12:25 pm-4:35 pm

2 stops28h 10m

$646

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Mon 5/12

5:00 pm-1:50 am

1 stop8h 50m

$209

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Wed 5/21

5:19 pm-10:13 pm

1 stop28h 54m

$247

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

Wed 5/21

10:14 am-10:13 pm

2 stops35h 59m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 13 results
1
2

Best time to book a flight from Key Largo to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santa Cruz de la Sierra

How far ahead should I book a flight from Key Largo to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Santa Cruz de la Sierra. Price data was last updated on April 25, 2025.

Booking 85 days in advance of your planned departure date is, on average, the best time to get cheap flights from Key Largo to Santa Cruz de la Sierra. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Key Largo to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Key Largo to Santa Cruz de la Sierra (average of $597). Flying from Key Largo to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to VVI?

Find hourly flight availability from Key Largo to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Key Largo to Santa Cruz de la Sierra, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Santa Cruz de la Sierra?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Santa Cruz de la Sierra. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Santa Cruz de la Sierra flight should consider departing on Sunday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated April 30, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines, Copa Airlines and United Airlines from Key Largo to Santa Cruz de la Sierra to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,767 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,767 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Copa Airlines
7.5
Good
1,411 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
United Airlines
7.4
Good
8,696 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
GOL
7.3
Good
1,068 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
BoA
6.7
Okay
133 reviews
LATAM Airlines
7.5
Good
1,767 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Comfort

7.4

Crew

8.1

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Key Largo?

    For a flight from Key Largo to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city. Viru Viru Intl is the only Santa Cruz de la Sierra airport and it handles 0 inbound flights from Key Largo per day. 4 airlines have flights to Santa Cruz de la Sierra Viru Viru Intl from Key Largo on a regular basis.

  • How popular is this Key Largo to Santa Cruz de la Sierra flight route?

    Flights from Key Largo to Santa Cruz de la Sierra Viru Viru Intl have been viewed 17 times in the past calendar month.

  • What are the cheapest airlines to fly from Key Largo to Santa Cruz de la Sierra one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $209. Copa Airlines flights start at $247 while deals on United Airlines start at $284 one-way.

  • What are the cheapest flights from Key Largo to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $289. While the most popular route (Miami - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $462 on average our data indicates $1,023 when flying from Key Largo to Santa Cruz de la Sierra.

  • Can I find deals for flights from Key Largo to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Key Largo to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Key Largo to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Key Largo to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Key Largo to Santa Cruz de la Sierra (average of $597). Flying from Key Largo to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Key Largo to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Key Largo to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$376Average$552FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$379Average$546FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$524Average$615FlexibilityNo cancel feeOn-time81%
BoACheapest$541Average$692FlexibilityNo cancel feeOn-timeN/A

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