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Santa Cruz de la Sierra

$213+ Cheap flights from Key Largo, FL to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — VVI
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Santa Cruz de la Sierra Viru Viru Intl are usually found in April or March, booked 49 days in advance, depart on a Thursday or Tuesday and return on a Friday

Cheap flight deals from Key Largo to Santa Cruz de la Sierra

Keep the following information in mind while searching for Key Largo to Santa Cruz de la Sierra flight deals. Data was last updated junio 12, 2025.

Round-trip from

$481
(Cheapflightsfares)

One-way from

$213
(FlightHub)

Popular in

December

Cheapest in

April

Average price

$662
From Key Largo to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Key Largo to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 9% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Key Largo to Santa Cruz de la Sierra

Cheapest flights from Key Largo to Santa Cruz de la Sierra
Explore the most affordable flight options available from Key Largo to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/1111:20 amMIA - VVI
1 stop14h 30mAvianca
dom. 8/242:55 amVVI - MIA
1 stop15h 00mAvianca
Deal found 6/11$481
This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/32:20 pmMIA - VVI
1 stop13h 18mCopa Airlines
jue. 9/2512:15 pmVVI - MIA
1 stop10h 28mCopa Airlines
Deal found 6/10$489
This Trip.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/112:55 pmMIA - VVI
2 stops12h 40mLATAM Airlines
sáb. 11/295:20 amVVI - MIA
1 stop15h 10mLATAM Airlines
Deal found 6/11$518
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/126:24 amMIA - VVI
1 stop15h 55mMultiple Airlines
sáb. 8/232:55 amVVI - MIA
1 stop15h 00mMultiple Airlines
Deal found 6/11$569
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/58:40 amMIA - VVI
2 stops37h 45mUnited Airlines
dom. 9/71:09 amVVI - MIA
2 stops33h 53mUnited Airlines
Deal found 6/10$592
This Trip.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/1112:00 pmMIA - VVI
Nonstop6h 50mBoA
dom. 8/2411:35 pmVVI - MIA
Nonstop6h 50mBoA
Deal found 6/11$625
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/1510:35 pmMIA - VVI
2 stops36h 30mGOL
mié. 10/291:10 pmVVI - MIA
2 stops27h 25mGOL
Deal found 6/10$637

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Key Largo to Santa Cruz de la Sierra that are best for you.

Fly from

Key Largo

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

lun. 8/11

11:20 am-1:50 am

1 stop14h 30m

Santa Cruz de la Sierra Viru Viru Intl

dom. 8/24

2:55 am-5:55 pm

1 stop15h 00m

$481

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

mié. 9/3

2:20 pm-3:38 am

1 stop13h 18m

Santa Cruz de la Sierra Viru Viru Intl

jue. 9/25

12:15 pm-10:43 pm

1 stop10h 28m

$489

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

mar. 11/11

2:55 pm-4:35 am

2 stops12h 40m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 11/29

5:20 am-7:30 pm

1 stop15h 10m

$518

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

mar. 8/12

6:24 am-10:19 pm

1 stop15h 55m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 8/23

2:55 am-5:55 pm

1 stop15h 00m

$569

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

vie. 9/5

8:40 am-10:25 pm

2 stops37h 45m

Santa Cruz de la Sierra Viru Viru Intl

dom. 9/7

1:09 am-11:02 am

2 stops33h 53m

$592

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

lun. 8/11

12:00 pm-6:50 pm

Nonstop6h 50m

Santa Cruz de la Sierra Viru Viru Intl

dom. 8/24

11:35 pm-6:25 am

Nonstop6h 50m

$625

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

mié. 10/15

10:35 pm-11:05 am

2 stops36h 30m

Santa Cruz de la Sierra Viru Viru Intl

mié. 10/29

1:10 pm-4:35 pm

2 stops27h 25m

$637

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

jue. 8/21

7:55 am-1:50 am

1 stop17h 55m

$213

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

mié. 7/16

8:34 am-10:19 pm

1 stop13h 45m

$240

MiamiSanta Cruz de la Sierra

MIA - VVI

MIAVVI

Miami

jue. 9/4

8:40 am-10:25 pm

2 stops37h 45m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 13 results
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Best time to book a flight from Key Largo to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Santa Cruz de la Sierra

How far ahead should I book a flight from Key Largo to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Santa Cruz de la Sierra. Price data was last updated on June 9, 2025.

Booking 49 days in advance of your planned departure date is, on average, the best time to get cheap flights from Key Largo to Santa Cruz de la Sierra. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Key Largo to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Key Largo to Santa Cruz de la Sierra (average of $597). Flying from Key Largo to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to VVI?

Find hourly flight availability from Key Largo to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Key Largo to Santa Cruz de la Sierra, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Santa Cruz de la Sierra?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Santa Cruz de la Sierra. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Santa Cruz de la Sierra flight should consider departing on Sunday at noon when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated junio 12, 2025.
Peruse reviews from past customers who have flown with LATAM Airlines, Copa Airlines and United Airlines from Key Largo to Santa Cruz de la Sierra to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,785 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,785 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Copa Airlines
7.5
Good
1,451 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
United Airlines
7.4
Good
8,790 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
GOL
7.3
Good
1,073 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
BoA
6.7
Okay
135 reviews
LATAM Airlines
7.5
Good
1,785 reviews

Food

6.7

Entertainment

7.0

Boarding

7.6

Overall

7.5

Comfort

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Key Largo?

    For a flight from Key Largo to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city. Viru Viru Intl is the only Santa Cruz de la Sierra airport and it handles 0 inbound flights from Key Largo per day. 4 airlines have flights to Santa Cruz de la Sierra Viru Viru Intl from Key Largo on a regular basis.

  • How popular is this Key Largo to Santa Cruz de la Sierra flight route?

    Flights from Key Largo to Santa Cruz de la Sierra Viru Viru Intl have been viewed 13 times in the past calendar month.

  • What are the cheapest airlines to fly from Key Largo to Santa Cruz de la Sierra one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $213. Copa Airlines flights start at $240 while deals on United Airlines start at $274 one-way.

  • What are the cheapest flights from Key Largo to Santa Cruz de la Sierra?

    Looking at all options, your cheapest flight can be booked for $271. While the most popular route (Miami - Santa Cruz de la Sierra Viru Viru Intl) can be booked for $488 on average our data indicates $1,025 when flying from Key Largo to Santa Cruz de la Sierra.

  • Can I find deals for flights from Key Largo to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Key Largo to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Key Largo to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Key Largo to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Key Largo to Santa Cruz de la Sierra (average of $597). Flying from Key Largo to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Key Largo to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Key Largo to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$376Average$539FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$379Average$546FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$528Average$633FlexibilityNo cancel feeOn-time81%
BoACheapest$536Average$693FlexibilityNo cancel feeOn-timeN/A

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