What are the cheapest airlines to fly from Irvine to Santa Cruz de la Sierra one-way?

The cheapest airlines for a one-way flight from Irvine to Santa Cruz de la Sierra are United Airlines ($520), Avianca ($857), and Copa Airlines ($1,356).

What is the cheapest day to fly from Irvine to Santa Cruz de la Sierra?

Travelers seeking maximum savings on their Irvine to Santa Cruz de la Sierra flight should consider departing on Thursday afternoons when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Irvine to Santa Cruz de la Sierra?

The most popular airlines flying from Irvine to Santa Cruz de la Sierra are Avianca, Copa Airlines and LATAM Airlines. Something to consider prior to booking your flight.

How far in advance should I book a flight from Irvine to Santa Cruz de la Sierra?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 42 days in advance, which can save you up to 21% on flights from Irvine to Santa Cruz de la Sierra compared to booking the week you need them. Waiting 42 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $674. For sooner than that we have options available in the next 3 days from $899.

What is the cheapest month to fly from Irvine to Santa Cruz de la Sierra?

Flights from Irvine to Santa Cruz de la Sierra lean towards being more expensive in December. Prices are generally better when you fly from Irvine to Santa Cruz de la Sierra in March, with the cheapest ticket starting at $588.

What airport do you fly into for flights to Santa Cruz de la Sierra from Irvine?

Most people fly into Santa Cruz de la Sierra Viru Viru Intl (VVI) if they book a flight to Santa Cruz de la Sierra from Irvine. On average, Viru Viru Intl has 0 inbound flights from Irvine per day from 4 airlines. Santa Cruz de la Sierra Viru Viru Intl is conveniently located just 11.5 mi from Santa Cruz de la Sierra’s city center.

Can I find deals for flights from Irvine to Santa Cruz de la Sierra that include hotel bookings?

Yes. In addition to deals on Irvine to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Irvine to Santa Cruz de la Sierra?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santa Cruz de la Sierra.

Can I find deals for business class flights from Irvine to Santa Cruz de la Sierra?

Yes. Cheapflights offers flight deals from Irvine to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$520+ Flights from Irvine to Santa Cruz de la Sierra

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Irvine to Santa Cruz de la Sierra Viru Viru Intl are usually found in March or April, booked 87 days in advance, depart on a Sunday or Wednesday and return on a Monday

Cheap flight deals from Irvine to Santa Cruz de la Sierra

Round-trip from	$639 (Cheapflightsfares)
One-way from	$520 (United Airlines)
Popular in	December
Cheapest in	March
Average price	$738

From Irvine to Santa Cruz de la Sierra Viru Viru Intl

Search Deals

One-way flight from Irvine to Santa Cruz de la Sierra Viru Viru Intl

Search Deals

Highest demand for flights based on searches. 17% potential increase in price ($170 potential increase over avg. RT price).

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Cheapest flight prices on average. 5% potential price decrease ($45 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Find flight deals from Irvine to Santa Cruz de la Sierra

Cheapest flights from Irvine to Santa Cruz de la Sierra
Explore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Wed 7/302:50 pmLAX - VVI

2 stops32h 00mAvianca

Sun 8/172:55 amVVI - LAX

2 stops22h 35mAvianca

Deal found 6/11

$640

Mon 6/166:10 pmLAX - VVI

2 stops25h 03mUnited Airlines

Wed 7/301:09 amVVI - LAX

2 stops33h 27mUnited Airlines

Deal found 6/12

$651

Tue 7/2910:04 pmLAX - VVI

1 stop21h 15mCopa Airlines

Tue 8/1912:15 pmVVI - LAX

1 stop13h 58mCopa Airlines

Deal found 6/10

$735

Wed 7/94:50 pmLAX - VVI

3 stops30h 00mMultiple Airlines

Tue 7/152:55 amVVI - LAX

3 stops23h 12mMultiple Airlines

Deal found 6/10

$897

Mon 12/811:20 amLAX - VVI

1 stop13h 15mLATAM Airlines

Sat 2/285:20 amVVI - LAX

1 stop16h 35mLATAM Airlines

Deal found 6/11

$1,015

Best flights from Irvine to Santa Cruz de la Sierra
Discover carefully curated flight deals from Irvine to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2025.

Thu 9/1112:30 amLAX - VVI

2 stops22h 20mAvianca

Sat 9/202:55 amVVI - LAX

2 stops22h 35mAvianca

Deal found 6/12

$639

Thu 9/111:59 amLAX - VVI

1 stop22h 39mCopa Airlines

Sat 9/201:09 amVVI - LAX

1 stop14h 22mCopa Airlines

Deal found 6/12

$665

Tue 7/2912:56 amLAX - VVI

2 stops18h 23mUnited Airlines

Sun 8/171:09 amVVI - LAX

2 stops33h 23mUnited Airlines

Deal found 6/12

$697

Wed 7/94:50 pmLAX - VVI

3 stops30h 00mMultiple Airlines

Tue 7/152:55 amVVI - LAX

3 stops23h 12mMultiple Airlines

Deal found 6/10

$897

Fri 9/1211:30 amLAX - VVI

1 stop14h 05mLATAM Airlines

Sun 9/215:20 amVVI - LAX

1 stop16h 35mLATAM Airlines

Deal found 6/12

$1,000

Last-minute flights from Irvine to Santa Cruz de la Sierra
Discover last-minute flight deals from Irvine to Santa Cruz de la Sierra. Data last updated June 12, 2025 and is based on user searches.

Mon 6/166:10 pmLAX - VVI

2 stops25h 03mUnited Airlines

Wed 7/301:09 amVVI - LAX

2 stops33h 27mUnited Airlines

Deal found 6/12

$651

Wed 6/182:10 amLAX - VVI

1 stop17h 03mCopa Airlines

Mon 6/231:09 amVVI - LAX

1 stop14h 38mCopa Airlines

Deal found 6/12

$1,173

Thu 6/197:25 pmLAX - VVI

2 stops47h 48mUnited Airlines

Mon 6/231:09 amVVI - LAX

2 stops19h 47mUnited Airlines

Deal found 6/12

$658

Thu 6/192:50 pmLAX - VVI

3 stops32h 00mAvianca

Tue 7/222:55 amVVI - LAX

2 stops23h 15mAvianca

Deal found 6/12

$765

Thu 6/197:20 pmLAX - VVI

2 stops47h 53mMultiple Airlines

Tue 7/222:55 amVVI - LAX

2 stops37h 35mMultiple Airlines

Deal found 6/12

$813

Thu 6/1911:30 amLAX - VVI

1 stop14h 05mLATAM Airlines

Wed 7/235:20 amVVI - LAX

1 stop16h 35mLATAM Airlines

Deal found 6/12

$1,097

Wed 7/94:50 pmLAX - VVI

3 stops30h 00mMultiple Airlines

Tue 7/152:55 amVVI - LAX

3 stops23h 12mMultiple Airlines

Deal found 6/10

$897

Wed 7/911:30 amLAX - VVI

1 stop14h 05mLATAM Airlines

Wed 7/165:20 amVVI - LAX

1 stop16h 35mLATAM Airlines

Deal found 6/10

$1,050

Tue 7/2910:04 pmLAX - VVI

1 stop21h 15mCopa Airlines

Tue 8/1912:15 pmVVI - LAX

1 stop13h 58mCopa Airlines

Deal found 6/10

$735

Wed 7/302:50 pmLAX - VVI

2 stops32h 00mAvianca

Sun 8/172:55 amVVI - LAX

2 stops22h 35mAvianca

Deal found 6/11

$640

One-way flights from Irvine to Santa Cruz de la Sierra
Search for one-way flight options from Irvine to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated June 12, 2025.

Wed 6/258:05 amLAX - VVI

2 stops35h 08mUnited Airlines

Deal found 6/9

$520

Wed 7/233:55 pmLAX - VVI

2 stops30h 55mAvianca

Deal found 6/9

$857

Wed 7/237:50 pmLAX - VVI

3 stops29h 45mMultiple Airlines

Deal found 6/9

$1,244

Tue 7/221:59 amLAX - VVI

1 stop22h 40mCopa Airlines

Deal found 6/9

$1,356

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 7/30

2:50 pm-1:50 am

2 stops32h 00m

Santa Cruz de la Sierra Viru Viru Intl

Sun 8/17

2:55 am-10:30 pm

2 stops22h 35m

$640

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Mon 6/16

6:10 pm-10:13 pm

2 stops25h 03m

Santa Cruz de la Sierra Viru Viru Intl

Wed 7/30

1:09 am-7:36 am

2 stops33h 27m

$651

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Tue 7/29

10:04 pm-10:19 pm

1 stop21h 15m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/19

12:15 pm-11:13 pm

1 stop13h 58m

$735

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 7/9

4:50 pm-1:50 am

3 stops30h 00m

Santa Cruz de la Sierra Viru Viru Intl

Tue 7/15

2:55 am-11:07 pm

3 stops23h 12m

$897

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 7/30

9:25 pm-4:35 am

1 stop28h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 8/18

5:20 am-6:55 pm

1 stop16h 35m

$1,040

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 6/25

8:05 am-10:13 pm

2 stops35h 08m

$520

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 7/23

3:55 pm-1:50 am

2 stops30h 55m

$857

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 7/23

7:50 pm-4:35 am

3 stops29h 45m

$1,244

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Tue 7/22

1:59 am-3:39 am

1 stop22h 40m

$1,356

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Best time to book a flight from Irvine to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Irvine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santa Cruz de la Sierra

How far ahead should I book a flight from Irvine to Santa Cruz de la Sierra?

The price you pay for your flight from Irvine to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 87 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $597). Flying from Irvine to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to VVI?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santa Cruz de la Sierra as you normally would.

Reviews of airlines servicing Santa Cruz de la Sierra

Get a feel of what it's like to fly with LATAM Airlines, Copa Airlines and United Airlines from Irvine to Santa Cruz de la Sierra by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

LATAM Airlines

7.5

Good

1,785 reviews

Reviews

1 / 20

6.0

Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

LATAM Airlines

7.5

Good

1,785 reviews

LATAM Airlines

7.5

Good

1,785 reviews

Reviews

1 / 20

6.0

Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Copa Airlines

7.5

Good

1,451 reviews

LATAM Airlines

7.5

Good

1,785 reviews

Reviews

1 / 20

6.0

Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

United Airlines

7.4

Good

8,790 reviews

LATAM Airlines

7.5

Good

1,785 reviews

Reviews

1 / 20

6.0

Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Avianca

6.7

Okay

2,345 reviews

LATAM Airlines

7.5

Good

1,785 reviews

Reviews

1 / 20

6.0

Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

What airport do you fly into for flights to Santa Cruz de la Sierra from Irvine?
Most people fly into Santa Cruz de la Sierra Viru Viru Intl (VVI) if they book a flight to Santa Cruz de la Sierra from Irvine. On average, Viru Viru Intl has 0 inbound flights from Irvine per day from 4 airlines. Santa Cruz de la Sierra Viru Viru Intl is conveniently located just 11.5 mi from Santa Cruz de la Sierra’s city center.
What are the cheapest airlines to fly from Irvine to Santa Cruz de la Sierra one-way?
The cheapest airlines for a one-way flight from Irvine to Santa Cruz de la Sierra are United Airlines ($520), Avianca ($857), and Copa Airlines ($1,356).
Can I find deals for flights from Irvine to Santa Cruz de la Sierra that include hotel bookings?
Yes. In addition to deals on Irvine to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Irvine to Santa Cruz de la Sierra?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santa Cruz de la Sierra.
Can I find deals for business class flights from Irvine to Santa Cruz de la Sierra?
Yes. Cheapflights offers flight deals from Irvine to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?
Currently, October is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $597). Flying from Irvine to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Irvine to Santa Cruz de la Sierra

Top 4 airlines flying from Irvine to Santa Cruz de la Sierra

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$565	Average$670	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$588	Average$762	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$629	Average$769	FlexibilityNo cancel fee	On-time69%
LATAM Airlines	Cheapest$1,030	Average$1,166	FlexibilityNo cancel fee	On-time81%

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$520+ Cheap flights from Irvine, CA to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Irvine to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Irvine to Santa Cruz de la Sierra Viru Viru Intl are usually found in March or April, booked 87 days in advance, depart on a Sunday or Wednesday and return on a Monday

Cheap flight deals from Irvine to Santa Cruz de la Sierra

Keep the following information in mind while searching for Irvine to Santa Cruz de la Sierra flight deals. Data was last updated June 12, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Irvine to Santa Cruz de la Sierra

Cheapest flights from Irvine to Santa Cruz de la SierraExplore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Explore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santa Cruz de la Sierra that are best for you.

Best time to book a flight from Irvine to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Irvine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santa Cruz de la Sierra

How far ahead should I book a flight from Irvine to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santa Cruz de la Sierra. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

What is the cheapest time of day to fly from IR9 to VVI?

Find hourly flight availability from Irvine to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Reviews of airlines servicing Santa Cruz de la Sierra

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santa Cruz de la Sierra from Irvine?

What are the cheapest airlines to fly from Irvine to Santa Cruz de la Sierra one-way?

Can I find deals for flights from Irvine to Santa Cruz de la Sierra that include hotel bookings?

How can I find direct flights from Irvine to Santa Cruz de la Sierra?

Can I find deals for business class flights from Irvine to Santa Cruz de la Sierra?

What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Irvine to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Irvine to Santa Cruz de la Sierra

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Cheapest flights from Irvine to Santa Cruz de la Sierra
Explore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.