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Santa Cruz de la Sierra

$295+ Cheap flights from Irvine, CA to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — VVI
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Irvine to Santa Cruz de la Sierra

Cheapest flights from Irvine to Santa Cruz de la Sierra
Explore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:55 pm
LAX
-
VVI
2 stops22h 40m
Avianca
Fri 3/63:40 am
VVI
-
LAX
2 stops22h 20m
Avianca
Deal found 1/28$639
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:50 pm
LAX
-
VVI
2 stops32h 45m
Avianca
Tue 3/33:40 am
VVI
-
LAX
2 stops22h 20m
Avianca
Deal found 1/27$640
This Priceline deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/122:50 pm
LAX
-
VVI
3 stops32h 45m
Avianca
Tue 3/173:40 am
VVI
-
LAX
2 stops21h 35m
Avianca
Deal found 1/26$645
This KAYAK deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:45 pm
LAX
-
VVI
2 stops25h 05m
Copa Airlines
Mon 4/611:48 am
VVI
-
LAX
2 stops31h 42m
Copa Airlines
Deal found 1/28$647
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:15 am
LAX
-
VVI
2 stops23h 15m
Avianca
Fri 5/13:35 am
VVI
-
LAX
2 stops21h 35m
Avianca
Deal found 1/28$648
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:45 pm
LAX
-
VVI
2 stops24h 57m
United Airlines
Thu 4/1611:48 am
VVI
-
LAX
2 stops28h 45m
United Airlines
Deal found 1/27$653
This Copa Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:01 am
LAX
-
VVI
1 stop22h 43m
Copa Airlines
Sat 3/711:54 am
VVI
-
LAX
1 stop14h 45m
Copa Airlines
Deal found 1/29$658
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:00 am
LAX
-
VVI
2 stops41h 40m
United Airlines
Tue 4/1411:48 am
VVI
-
LAX
2 stops24h 52m
United Airlines
Deal found 1/27$661

Find flight deals from Irvine to Santa Cruz de la Sierra

Keep the following information in mind while searching for Irvine to Santa Cruz de la Sierra flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$639
(Priceline)

One-way from

$295
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$717
Provider with most accurate pricing for Los Angeles-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Irvine to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Irvine to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($87 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Irvine to Santa Cruz de la Sierra that are best for you.

Fly from

Irvine

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Fri 2/27

12:25 pm-2:35 am

2 stops34h 10m

Santa Cruz de la Sierra Viru Viru Intl

Fri 3/6

3:40 am-10:55 am

2 stops35h 15m

$641

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Thu 3/12

2:50 pm-2:35 am

3 stops32h 45m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/17

3:40 am-10:15 pm

2 stops21h 35m

$645

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Mon 4/6

6:45 am-3:40 am

2 stops17h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/13

11:48 am-8:20 pm

2 stops35h 32m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Tue 4/7

11:59 pm-3:40 am

2 stops24h 41m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

11:48 am-7:28 am

2 stops22h 40m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sat 3/28

5:19 pm-10:50 pm

2 stops26h 31m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

11:48 am-6:10 pm

2 stops33h 22m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Mon 4/6

6:45 am-3:40 am

2 stops17h 55m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

11:48 am-7:28 am

2 stops22h 40m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 4/8

5:50 am-3:40 am

2 stops18h 50m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/14

11:48 am-6:10 pm

2 stops33h 22m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sat 2/28

11:59 pm-3:38 am

2 stops23h 39m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/31

11:47 am-4:30 pm

2 stops31h 43m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sat 4/4

12:55 am-3:40 am

2 stops23h 45m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

11:48 am-10:35 am

2 stops25h 47m

$653

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 4/8

11:02 pm-10:42 pm

2 stops20h 40m

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

11:48 am-11:20 am

2 stops26h 32m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 21 results
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Best time to book a flight from Irvine to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santa Cruz de la Sierra

How far ahead should I book a flight from Irvine to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santa Cruz de la Sierra. Price data was last updated on January 23, 2026.

The price you pay for your flight from Irvine to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 25 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

Currently, February is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $513). Flying from Irvine to Santa Cruz de la Sierra in July is currently the most expensive (average of $642). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated January 29, 2026.
Read through reviews of airlines operating flights from Irvine to Santa Cruz de la Sierra, such as LATAM Airlines, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
LATAM Airlines
7.5
Good
1,918 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
Copa Airlines
7.5
Good
1,560 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
United Airlines
7.4
Good
9,215 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.
Avianca
6.6
Okay
2,492 reviews
LATAM Airlines
7.5
Good
1,918 reviews

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Food

6.7

Crew

8.0

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

JC,Jan 2026

FLN - GRU

Plane was late in FLN and missed connection in GRU. No alternative was given to me until 6 hours later and I was delayed by over 12 hours total.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Irvine?

    Most people fly into Santa Cruz de la Sierra Viru Viru Intl (VVI) if they book a flight to Santa Cruz de la Sierra from Irvine. On average, Viru Viru Intl has 0 inbound flights from Irvine per day from 4 airlines. Santa Cruz de la Sierra Viru Viru Intl is conveniently located just 11.5 mi from Santa Cruz de la Sierra’s city center.

  • How long is the flight from Irvine to Santa Cruz de la Sierra?

    There are many flights that can get you from Irvine to Santa Cruz de la Sierra in 17h 55m. Fly via Avianca or United Airlines to get the fastest option. There are 5087 mi between Irvine and Santa Cruz de la Sierra. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Irvine to Santa Cruz de la Sierra one-way?

    The cheapest airlines for a one-way flight from Irvine to Santa Cruz de la Sierra are Avianca ($252), United Airlines ($264), and Copa Airlines ($281).

  • Can I find deals for flights from Irvine to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Irvine to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Irvine to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Irvine to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

    Currently, February is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $513). Flying from Irvine to Santa Cruz de la Sierra in July is currently the most expensive (average of $642). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Irvine to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Irvine to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Irvine to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$556Average$703FlexibilityNo cancel feeOn-time70%
AviancaCheapest$580Average$650FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$631Average$631FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$1,034Average$1,186FlexibilityNo cancel feeOn-time81%

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