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Santa Cruz de la Sierra

$285+ Cheap flights from Irvine, CA to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — VVI
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Irvine to Santa Cruz de la Sierra Viru Viru Intl are usually found in September or April, booked 87 days in advance, depart on a Sunday or Wednesday and return on a Monday

Cheap flight deals from Irvine to Santa Cruz de la Sierra

Keep the following information in mind while searching for Irvine to Santa Cruz de la Sierra flight deals. Data was last updated September 15, 2025.

Round-trip from

$631
(United Airlines)

One-way from

$285
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$627
From Irvine to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Irvine to Santa Cruz de la Sierra Viru Viru Intl
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Highest demand for flights based on searches. 18% potential increase in price ($169 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($36 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Irvine to Santa Cruz de la Sierra

Cheapest flights from Irvine to Santa Cruz de la Sierra
Explore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1511:50 pmLAX - VVI
2 stops23h 00mAvianca
Wed 9/172:50 amVVI - LAX
2 stops36h 10mAvianca
Deal found 9/13$582
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:31 amLAX - VVI
2 stops38h 09mUnited Airlines
Tue 10/141:09 amVVI - LAX
2 stops33h 24mUnited Airlines
Deal found 9/15$631
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/71:00 amLAX - VVI
2 stops21h 50mAvianca
Tue 10/142:50 amVVI - LAX
2 stops23h 20mAvianca
Deal found 9/14$639
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:50 pmLAX - VVI
2 stops32h 00mAvianca
Wed 10/222:50 amVVI - LAX
2 stops23h 20mAvianca
Deal found 9/13$640
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/161:00 amLAX - VVI
2 stops21h 50mAvianca
Thu 9/182:50 amVVI - LAX
2 stops22h 40mAvianca
Deal found 9/13$649
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:55 amLAX - VVI
2 stops41h 51mUnited Airlines
Mon 1/121:15 amVVI - LAX
2 stops26h 28mUnited Airlines
Deal found 9/13$671
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/72:01 amLAX - VVI
1 stop22h 35mCopa Airlines
Tue 10/141:09 amVVI - LAX
1 stop14h 21mCopa Airlines
Deal found 9/15$685

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Irvine to Santa Cruz de la Sierra that are best for you.

Fly from

Irvine

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Tue 9/30

12:56 am-10:40 pm

2 stops42h 44m

Santa Cruz de la Sierra Viru Viru Intl

Fri 10/10

1:09 am-9:03 pm

2 stops22h 54m

$631

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 10/8

5:31 am-10:40 pm

2 stops38h 09m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/14

1:09 am-8:58 am

2 stops34h 49m

$631

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Thu 9/25

12:56 am-10:25 pm

2 stops42h 29m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/14

1:09 am-7:33 am

2 stops33h 24m

$631

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 10/22

12:56 am-10:40 pm

2 stops42h 44m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/1

1:09 am-8:35 am

2 stops34h 26m

$631

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sun 9/21

1:00 am-1:50 am

2 stops21h 50m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/29

2:50 am-11:10 pm

2 stops23h 20m

$639

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Tue 10/7

1:00 am-1:50 am

2 stops21h 50m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/14

2:50 am-11:10 pm

2 stops23h 20m

$639

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sat 10/18

5:00 pm-10:40 pm

2 stops26h 40m

$285

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Thu 9/18

9:30 pm-10:25 pm

2 stops45h 55m

$289

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Mon 10/27

12:55 am-10:40 pm

2 stops18h 45m

$289

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Fri 10/17

1:00 am-1:50 am

2 stops21h 50m

$296

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 13 results
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Best time to book a flight from Irvine to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santa Cruz de la Sierra

How far ahead should I book a flight from Irvine to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santa Cruz de la Sierra. Price data was last updated on September 12, 2025.

The price you pay for your flight from Irvine to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 87 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

Currently, October is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $597). Flying from Irvine to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to VVI?

Find hourly flight availability from Irvine to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santa Cruz de la Sierra as you normally would.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from Irvine to Santa Cruz de la Sierra, such as Copa Airlines, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,847 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
8,929 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Crew

8.1

Entertainment

6.8

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Irvine?

    Most people fly into Santa Cruz de la Sierra Viru Viru Intl (VVI) if they book a flight to Santa Cruz de la Sierra from Irvine. On average, Viru Viru Intl has 0 inbound flights from Irvine per day from 4 airlines. Santa Cruz de la Sierra Viru Viru Intl is conveniently located just 11.5 mi from Santa Cruz de la Sierra’s city center.

  • How long is the flight from Irvine to Santa Cruz de la Sierra?

    There are many flights that can get you from Irvine to Santa Cruz de la Sierra in 42h 44m. Fly via United Airlines to get the fastest option. There are 5087 mi between Irvine and Santa Cruz de la Sierra.

  • Can I find deals for flights from Irvine to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Irvine to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Irvine to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Irvine to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $597). Flying from Irvine to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Irvine to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Irvine to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Irvine to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$556Average$719FlexibilityNo cancel feeOn-time70%
AviancaCheapest$565Average$658FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$631Average$783FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$1,030Average$1,164FlexibilityNo cancel feeOn-time81%

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