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Santa Cruz de la Sierra

$269+ Cheap flights from Irvine, CA to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — VVI
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Irvine to Santa Cruz de la Sierra Viru Viru Intl are usually found in September or November, booked 26 days in advance, depart on a Sunday or Wednesday and return on a Monday

Cheap flight deals from Irvine to Santa Cruz de la Sierra

Cheapest flights from Irvine to Santa Cruz de la Sierra
Explore the most affordable flight options available from Irvine to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amLAX - VVI
2 stops36h 46mUnited Airlines
Tue 12/3011:40 amVVI - LAX
2 stops38h 15mUnited Airlines
Deal found 12/17$808
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amLAX - VVI
2 stops36h 46mUnited Airlines
Thu 1/111:44 amVVI - LAX
2 stops24h 07mUnited Airlines
Deal found 12/16$957
This Ovago deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:30 amLAX - VVI
1 stop14h 05mLATAM Airlines
Sat 1/105:25 amVVI - LAX
1 stop29h 25mLATAM Airlines
Deal found 12/16$1,190
This FlightHub deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:30 amLAX - VVI
1 stop14h 05mLATAM Airlines
Tue 12/305:25 amVVI - LAX
1 stop16h 35mLATAM Airlines
Deal found 12/18$1,207
This Ovago deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:30 amLAX - VVI
1 stop14h 05mLATAM Airlines
Sat 12/205:25 amVVI - LAX
1 stop16h 35mLATAM Airlines
Deal found 12/15$1,270
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:00 pmLAX - VVI
2 stops33h 35mAvianca
Sun 12/213:40 amVVI - LAX
2 stops21h 35mAvianca
Deal found 12/15$1,274
This KAYAK deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:30 amLAX - VVI
1 stop14h 05mLATAM Airlines
Mon 12/225:25 amVVI - LAX
2 stops23h 20mLATAM Airlines
Deal found 12/15$1,291

Find flight deals from Irvine to Santa Cruz de la Sierra

Keep the following information in mind while searching for Irvine to Santa Cruz de la Sierra flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$516
(Cheapflightsfares)

One-way from

$269
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$1,019
Provider with most accurate pricing for Los Angeles-Santa Cruz de la Sierra Viru Viru Intl flight deals.
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Provider most trusted by Cheapflights users for Los Angeles-Santa Cruz de la Sierra Viru Viru Intl flights.
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From Irvine to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Irvine to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Irvine to Santa Cruz de la Sierra that are best for you.

Fly from

Irvine

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sun 2/1

1:50 pm-2:35 am

2 stops32h 45m

Santa Cruz de la Sierra Viru Viru Intl

Fri 2/20

3:40 am-10:55 am

3 stops35h 15m

$534

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Sat 2/7

11:05 pm-3:44 am

2 stops24h 39m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

11:42 am-9:43 am

2 stops25h 01m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Mon 3/16

4:54 pm-10:50 pm

2 stops26h 56m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/19

11:42 am-1:09 am

2 stops40h 27m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Fri 2/6

12:40 pm-10:50 pm

2 stops30h 10m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/12

11:42 am-8:51 am

2 stops24h 09m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Fri 2/6

1:25 pm-10:50 pm

2 stops29h 25m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:42 am-9:12 am

2 stops25h 30m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Mon 2/9

12:40 pm-10:50 pm

2 stops30h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

11:42 am-11:40 am

2 stops26h 58m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 3/4

12:55 am-10:50 pm

2 stops17h 55m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

11:42 am-6:42 pm

2 stops34h 00m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Fri 2/6

9:30 pm-10:50 pm

2 stops21h 20m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

11:42 am-9:43 am

2 stops25h 01m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 2/4

6:50 pm-10:50 pm

2 stops24h 00m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/9

11:42 am-1:43 pm

2 stops29h 01m

$632

Los AngelesSanta Cruz de la Sierra

LAX - VVI

LAXVVI

Los Angeles

Wed 2/4

4:49 pm-10:50 pm

2 stops26h 01m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:42 am-9:12 am

2 stops25h 30m

$632

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 19 results
1
2

Best time to book a flight from Irvine to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santa Cruz de la Sierra

How far ahead should I book a flight from Irvine to Santa Cruz de la Sierra?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santa Cruz de la Sierra. Price data was last updated on December 12, 2025.

The price you pay for your flight from Irvine to Santa Cruz de la Sierra may vary depending on when you book. For the best chance of a lower fare, look to book 25 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

Currently, February is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $498). Flying from Irvine to Santa Cruz de la Sierra in July is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to VVI?

Find hourly flight availability from Irvine to Santa Cruz de la Sierra. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Irvine to Santa Cruz de la Sierra in the evening. By choosing this option you can save up to 38% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Irvine to Santa Cruz de la Sierra?

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Irvine to Santa Cruz de la Sierra, such as Copa Airlines, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,893 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
9,093 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,490 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Crew

8.1

Overall

7.6

Boarding

7.8

Food

6.8

Comfort

7.4

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Irvine?

    Most people fly into Santa Cruz de la Sierra Viru Viru Intl (VVI) if they book a flight to Santa Cruz de la Sierra from Irvine. On average, Viru Viru Intl has 0 inbound flights from Irvine per day from 4 airlines. Santa Cruz de la Sierra Viru Viru Intl is conveniently located just 11.5 mi from Santa Cruz de la Sierra’s city center.

  • How long is the flight from Irvine to Santa Cruz de la Sierra?

    There are many flights that can get you from Irvine to Santa Cruz de la Sierra in 24h 39m. Fly via Avianca or United Airlines to get the fastest option. There are 5087 mi between Irvine and Santa Cruz de la Sierra. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Irvine to Santa Cruz de la Sierra one-way?

    The cheapest airlines for a one-way flight from Irvine to Santa Cruz de la Sierra are Avianca ($254), United Airlines ($264), and Copa Airlines ($272).

  • Can I find deals for flights from Irvine to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Irvine to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Irvine to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Irvine to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Santa Cruz de la Sierra?

    Currently, February is the cheapest month in which you can book a flight from Irvine to Santa Cruz de la Sierra (average of $498). Flying from Irvine to Santa Cruz de la Sierra in July is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Irvine to Santa Cruz de la Sierra

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Top 4 airlines flying from Irvine to Santa Cruz de la Sierra

Discover the top 4 airlines that operate flights from Irvine to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$556Average$692FlexibilityNo cancel feeOn-time70%
AviancaCheapest$580Average$655FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$631Average$631FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$1,030Average$1,154FlexibilityNo cancel feeOn-time81%

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