$297+ Cheap flights from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — VVI
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Find cheap flights from O'Hare Intl to Santa Cruz de la Sierra with Cheapflights
1. Tell us where you want to go
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from O'Hare Intl to Santa Cruz de la Sierra
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Cheapest flights from O'Hare Intl to Santa Cruz de la SierraExplore the most affordable flight options available from O'Hare Intl to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from O'Hare Intl to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:05 pm
ORD
- VVI
1 stop11h 35m
Copa Airlines
Tue 4/2111:48 am
VVI
- ORD
1 stop14h 25m
Copa Airlines
Deal found 3/11![Copa Airlines logo]()
$562
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/133:05 pm
ORD
- VVI
1 stop30h 37m
Copa Airlines
Wed 5/61:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$612
This Flightnetwork deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:05 pm
ORD
- VVI
1 stop30h 37m
Copa Airlines
Thu 5/711:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$624
This Flightnetwork deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 am
ORD
- VVI
1 stop18h 34m
Copa Airlines
Sat 5/21:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$628
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:05 pm
ORD
- VVI
1 stop11h 35m
Copa Airlines
Tue 5/51:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$634
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:06 am
ORD
- VVI
1 stop13h 36m
Copa Airlines
Mon 5/411:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$635
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:05 pm
ORD
- VVI
1 stop30h 37m
Copa Airlines
Sat 5/21:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$638
This Justfly.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Fri 6/53:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/9![Avianca logo]()
$639
This Justfly.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Sat 10/103:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/8![Avianca logo]()
$642
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:06 am
ORD
- VVI
1 stop18h 34m
Copa Airlines
Sat 5/211:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$647
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Tue 5/123:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/8![Avianca logo]()
$660
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:05 pm
ORD
- VVI
1 stop11h 35m
Copa Airlines
Mon 4/1311:48 am
VVI
- ORD
1 stop14h 25m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$661
Best flights from O'Hare Intl to Santa Cruz de la SierraDiscover carefully curated flight deals from O'Hare Intl to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from O'Hare Intl to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 am
ORD
- VVI
1 stop18h 34m
Copa Airlines
Tue 4/211:15 am
VVI
- ORD
1 stop13h 35m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$562
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:40 pm
ORD
- VVI
2 stops23h 58m
United Airlines
Tue 6/1611:47 am
VVI
- ORD
2 stops22h 35m
United Airlines
Deal found 3/8![United Airlines logo]()
$695
This Avianca deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Wed 4/153:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/12![Avianca logo]()
$700
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:05 pm
ORD
- VVI
1 stop11h 35m
Copa Airlines
Mon 4/1311:48 am
VVI
- ORD
1 stop14h 25m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:48 am
ORD
- VVI
2 stops20h 52m
United Airlines
Tue 4/2111:48 am
VVI
- ORD
2 stops22h 35m
United Airlines
Deal found 3/11![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:30 am
ORD
- VVI
2 stops19h 10m
United Airlines
Thu 5/711:47 am
VVI
- ORD
2 stops20h 39m
United Airlines
Deal found 3/12![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:48 am
ORD
- VVI
2 stops15h 54m
United Airlines
Tue 4/2811:48 am
VVI
- ORD
2 stops33h 27m
United Airlines
Deal found 3/11![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:30 pm
ORD
- VVI
2 stops24h 12m
United Airlines
Mon 4/1311:48 am
VVI
- ORD
2 stops22h 50m
United Airlines
Deal found 3/9![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:00 am
ORD
- VVI
2 stops19h 40m
United Airlines
Thu 4/1611:48 am
VVI
- ORD
2 stops23h 02m
United Airlines
Deal found 3/9![United Airlines logo]()
$715
Last-minute flights from O'Hare Intl to Santa Cruz de la SierraDiscover last-minute flight deals from O'Hare Intl to Santa Cruz de la Sierra. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from O'Hare Intl to Santa Cruz de la Sierra. Data last updated March 13, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:05 pm
ORD
- VVI
1 stop11h 35m
Copa Airlines
Mon 4/1311:48 am
VVI
- ORD
1 stop14h 25m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$661
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Wed 4/153:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/9![Avianca logo]()
$700
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:00 am
ORD
- VVI
2 stops19h 40m
United Airlines
Thu 4/1611:48 am
VVI
- ORD
2 stops23h 02m
United Airlines
Deal found 3/9![United Airlines logo]()
$715
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/133:05 pm
ORD
- VVI
1 stop30h 37m
Copa Airlines
Wed 5/61:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$612
This Justfly.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Sun 5/33:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/12![Avianca logo]()
$679
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:06 am
ORD
- VVI
1 stop13h 36m
Copa Airlines
Mon 5/411:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$635
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:06 am
ORD
- VVI
1 stop18h 34m
Copa Airlines
Sat 5/211:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$647
This Flightnetwork deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:05 pm
ORD
- VVI
1 stop30h 37m
Copa Airlines
Tue 5/51:12 am
VVI
- ORD
1 stop13h 54m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$624
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:05 pm
ORD
- VVI
1 stop30h 37m
Copa Airlines
Sat 5/21:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$638
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 am
ORD
- VVI
1 stop18h 34m
Copa Airlines
Tue 4/211:15 am
VVI
- ORD
1 stop13h 35m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$562
This Flightnetwork deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:06 am
ORD
- VVI
1 stop18h 34m
Copa Airlines
Sat 5/21:12 am
VVI
- ORD
1 stop25h 03m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$628
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:05 pm
ORD
- VVI
1 stop11h 35m
Copa Airlines
Tue 5/511:47 am
VVI
- ORD
1 stop27h 19m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$634
One-way flights from O'Hare Intl to Santa Cruz de la SierraSearch for one-way flight options from O'Hare Intl to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from O'Hare Intl to Santa Cruz de la Sierra. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Justfly.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/9![Avianca logo]()
$297
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:02 am
ORD
- VVI
1 stop18h 33m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/113:53 pm
ORD
- VVI
2 stops34h 38m
United Airlines
Deal found 3/9![United Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1612:59 am
ORD
- VVI
2 stops24h 31m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$352
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:25 am
ORD
- VVI
3 stops38h 13m
United Airlines
Deal found 3/11![United Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/318:05 am
ORD
- VVI
3 stops23h 05m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:05 am
ORD
- VVI
3 stops21h 30m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$392
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:20 pm
ORD
- VVI
3 stops30h 10m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$441
This Copa Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:02 am
ORD
- VVI
1 stop13h 36m
Copa Airlines
Deal found 3/12![Copa Airlines logo]()
$463
Find flight deals from O'Hare Intl to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from O'Hare Intl (ORD) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $562 (Copa Airlines) |
One-way from | $297 (Justfly.com) |
Popular in | July |
Cheapest in | August |
Average price | $628 |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Fri 4/17
8:06 am-3:40 am
1 stop18h 34m
Santa Cruz de la Sierra Viru Viru Intl
Tue 4/21
1:15 am-1:50 pm
1 stop13h 35m
$562
Quickest round-trip
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Fri 4/3
3:05 pm-3:40 am
1 stop11h 35m
Santa Cruz de la Sierra Viru Viru Intl
Mon 4/13
11:48 am-1:13 am
1 stop14h 25m
$661
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Tue 6/9
9:40 pm-10:38 pm
2 stops23h 58m
Santa Cruz de la Sierra Viru Viru Intl
Tue 6/16
11:47 am-9:22 am
2 stops22h 35m
$695
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Sun 4/12
11:20 pm-2:30 am
1 stop26h 10m
Santa Cruz de la Sierra Viru Viru Intl
Wed 4/15
3:35 am-9:20 pm
1 stop18h 45m
$700
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Fri 4/17
5:48 am-3:40 am
2 stops20h 52m
Santa Cruz de la Sierra Viru Viru Intl
Tue 4/21
11:48 am-9:23 am
2 stops22h 35m
$715
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Sun 4/12
7:30 am-3:40 am
2 stops19h 10m
Santa Cruz de la Sierra Viru Viru Intl
Thu 5/7
11:47 am-7:26 am
2 stops20h 39m
$715
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Tue 4/21
5:48 am-10:42 pm
2 stops15h 54m
Santa Cruz de la Sierra Viru Viru Intl
Tue 4/28
11:48 am-8:15 pm
2 stops33h 27m
$715
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Fri 4/3
9:30 pm-10:42 pm
2 stops24h 12m
Santa Cruz de la Sierra Viru Viru Intl
Mon 4/13
11:48 am-9:38 am
2 stops22h 50m
$715
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Sun 4/12
7:00 am-3:40 am
2 stops19h 40m
Santa Cruz de la Sierra Viru Viru Intl
Thu 4/16
11:48 am-9:50 am
2 stops23h 02m
$715
Cheapest one-way
ChicagoSanta Cruz de la Sierra
ORD - VVI
ORDVVI
Chicago O'Hare Intl
Thu 6/11
11:20 pm-2:30 am
1 stop26h 10m
$297
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from O'Hare Intl to Santa Cruz de la Sierra
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from O'Hare Intl to Santa Cruz de la Sierra in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago O'Hare Intl Airport-Santa Cruz de la Sierra flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from O'Hare Intl to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from O'Hare Intl with our price prediction graph.
ORD-VVI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra
Reviews of airlines servicing Santa Cruz de la Sierra
Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated March 13, 2026.
Read reviews from past customers who have flown Copa Airlines and United Airlines from Chicago O'Hare Intl Airport to Santa Cruz de la Sierra. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Crew
8.1
Overall
7.5
Comfort
7.4
Entertainment
6.8
Boarding
7.8
Food
6.8
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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O'Hare Intl and Santa Cruz de la Sierra flights
Browse other O'Hare Intl and Santa Cruz de la Sierra flight options. Last updated on March 13, 2026.
Other flights from O'Hare Intl
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Top 2 airlines flying from O'Hare Intl to Santa Cruz de la Sierra
Discover the top 2 airlines that operate flights from O'Hare Intl to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$278 | Average$603 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$458 | Average$682 | FlexibilityNo cancel fee | On-time70% |