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$342+ Cheap flights from Sicily to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
CTA — SFO
Mar 13 — Mar 201
Fri 3/13
Fri 3/20
1 adult, Economy
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Cheap flight deals from Sicily to San Francisco

Cheapest flights from Sicily to San Francisco
Explore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.

This lol.travel deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:10 pm
PMO
-
SFO
1 stop26h 55m
ITA Airways
Mon 3/94:05 pm
SFO
-
PMO
1 stop18h 20m
ITA Airways
Deal found 2/9$558
This lol.travel deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/303:10 pm
PMO
-
SFO
1 stop31h 05m
ITA Airways
Tue 4/1410:10 am
SFO
-
PMO
2 stops19h 55m
ITA Airways
Deal found 2/11$559
This lol.travel deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:20 am
PMO
-
SFO
2 stops20h 37m
ITA Airways
Wed 5/610:05 am
SFO
-
PMO
2 stops20h 20m
ITA Airways
Deal found 2/9$561
This Gotogate deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:30 pm
CTA
-
SFO
1 stop24h 35m
ITA Airways
Mon 3/164:05 pm
SFO
-
CTA
2 stops32h 50m
ITA Airways
Deal found 2/8$591
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:10 am
PMO
-
SFO
1 stop16h 05m
ITA Airways
Tue 4/143:15 pm
SFO
-
PMO
1 stop14h 10m
ITA Airways
Deal found 2/11$598
This lol.travel deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:10 am
PMO
-
SFO
1 stop16h 05m
ITA Airways
Sun 4/128:49 am
SFO
-
PMO
2 stops21h 36m
ITA Airways
Deal found 2/8$604
This lol.travel deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:30 pm
CTA
-
SFO
1 stop24h 35m
ITA Airways
Mon 3/234:05 pm
SFO
-
CTA
1 stop18h 25m
ITA Airways
Deal found 2/9$605
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:15 pm
PMO
-
SFO
2 stops31h 26m
American Airlines
Tue 4/145:32 am
SFO
-
PMO
2 stops21h 13m
American Airlines
Deal found 2/11$606
This lol.travel deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:15 pm
CTA
-
SFO
1 stop27h 00m
ITA Airways
Mon 9/143:15 pm
SFO
-
CTA
1 stop15h 30m
ITA Airways
Deal found 2/10$617
This KLM deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/195:00 pm
CTA
-
SFO
1 stop27h 45m
KLM
Sat 6/207:00 am
SFO
-
CTA
1 stop15h 55m
KLM
Deal found 2/8$647
This FlightHub deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:25 am
REG
-
SFO
1 stop15h 50m
ITA Airways
Tue 6/165:05 am
SFO
-
REG
2 stops24h 25m
ITA Airways
Deal found 2/8$663
This lol.travel deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:10 am
REG
-
SFO
1 stop15h 55m
ITA Airways
Thu 4/28:49 am
SFO
-
REG
2 stops28h 56m
ITA Airways
Deal found 2/9$674

Find flight deals from Sicily to San Francisco

Keep the following information in mind while searching for Sicily to San Francisco flight deals. Data was last updated February 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$558
(lol.travel)

One-way from

$342
(Kiwi.com)

Popular in

July

Cheapest in

May

Average price

$696
Provider with most accurate pricing for Catania Fontanarossa-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Catania Fontanarossa-San Francisco flights.
Search Deals
From Sicily to San Francisco
Search Deals
One-way flight from Sicily to San Francisco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.

Fly from

Sicily

Fly to

San Francisco

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 3/1

7:10 pm-1:05 pm

1 stop26h 55m

San Francisco

Mon 3/9

4:05 pm-6:25 pm

1 stop18h 20m

$558

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Wed 4/22

7:20 am-6:57 pm

2 stops20h 37m

San Francisco

Wed 5/6

10:05 am-3:25 pm

2 stops20h 20m

$561

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Sun 3/1

9:30 pm-1:05 pm

1 stop24h 35m

San Francisco

Mon 3/16

4:05 pm-8:55 am

2 stops32h 50m

$597

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 3/31

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Tue 4/14

3:15 pm-2:25 pm

1 stop14h 10m

$598

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 4/7

6:10 am-1:15 pm

1 stop16h 05m

San Francisco

Sun 4/12

8:49 am-3:25 pm

2 stops21h 36m

$604

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Sun 3/8

9:30 pm-2:05 pm

1 stop24h 35m

San Francisco

Mon 3/23

4:05 pm-6:30 pm

1 stop18h 25m

$605

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Mon 3/30

7:50 pm-7:47 pm

2 stops32h 57m

San Francisco

Thu 4/16

11:28 pm-5:55 pm

2 stops33h 27m

$606

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 3/31

12:15 pm-9:43 am

2 stops30h 28m

San Francisco

Thu 4/16

11:28 pm-5:55 pm

2 stops33h 27m

$606

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Tue 3/31

12:15 pm-9:43 am

2 stops30h 28m

San Francisco

Mon 4/13

4:35 pm-11:45 am

1 stop34h 10m

$606

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 4/23

12:05 pm-2:59 pm

2 stops35h 54m

San Francisco

Sun 4/26

1:28 pm-6:40 pm

2 stops20h 12m

$606

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 37 results
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Best time to book a flight from Sicily to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sicily with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sicily to San Francisco
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Sicily to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Sicily?

    For a flight from Sicily to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city.

  • How long is the flight from Sicily to San Francisco?

    A quick flight from Sicily to San Francisco can take about 23h 56m. ITA Airways provides one of the quickest options available for as low as $780. Airlines will cover a distance of 6527 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Sicily to San Francisco one-way?

    The cheapest airline one-way is ITA Airways, with whom users have recently found tickets for as low as $553. However, be on the lookout for offers from SWISS and Lufthansa, as they are both options that can get you from Sicily to San Francisco for a low price.

  • What are the most popular routes from Sicily to San Francisco?

    The most popular flight routes from Sicily to San Francisco are Palermo Punta Raisi - San Francisco, Catania Fontanarossa - San Francisco and Lamezia Terme Intl - San Francisco.

  • Can I find deals for flights from Sicily to San Francisco that include hotel bookings?

    Yes. In addition to deals on Sicily to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sicily to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sicily to San Francisco.

  • Can I find deals for business class flights from Sicily to San Francisco?

    Yes. Cheapflights offers flight deals from Sicily to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Santa Cruz
South San Francisco
Santa Clara
Roseville
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Redwood City
Rancho Cordova
San Lorenzo
Davis
Hollister
Manteca
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Sicily to San Francisco

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Top airline flying from Sicily to San Francisco

Discover the top airline that operate flights from Sicily to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$710Average$990FlexibilityNo cancel feeOn-time76%

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