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$421+ Cheap flights from Sicily to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
CTA — SFO
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Sicily to San Francisco

Cheapest flights from Sicily to San Francisco
Explore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This lol.travel deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amCTA - SFO
1 stop16h 05mITA Airways
Thu 11/273:05 pmSFO - CTA
1 stop20h 40mITA Airways
Deal found 11/5$614
This lol.travel deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:25 pmPMO - SFO
1 stop31h 40mITA Airways
Thu 11/273:05 pmSFO - PMO
1 stop14h 25mITA Airways
Deal found 11/6$617
This lol.travel deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:10 amREG - SFO
1 stop15h 55mMultiple Airlines
Wed 11/2611:08 amSFO - REG
2 stops18h 22mMultiple Airlines
Deal found 11/6$619
This Booking.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2112:10 pmPMO - SFO
2 stops22h 05mLufthansa
Thu 11/277:00 amSFO - PMO
2 stops19h 20mLufthansa
Deal found 11/6$709
This Ovago deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/199:30 pmCTA - SFO
1 stop24h 35mMultiple Airlines
Tue 11/258:08 pmSFO - CTA
2 stops33h 32mMultiple Airlines
Deal found 11/5$712
This lol.travel deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amCTA - SFO
2 stops20h 42mITA Airways
Sat 12/273:05 pmSFO - CTA
1 stop18h 25mITA Airways
Deal found 11/5$757
This lol.travel deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:50 pmCTA - SFO
2 stops28h 52mITA Airways
Mon 12/293:05 pmSFO - CTA
1 stop14h 35mITA Airways
Deal found 11/6$773
This lol.travel deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:10 amPMO - SFO
2 stops20h 32mITA Airways
Sat 12/273:05 pmSFO - PMO
1 stop14h 25mITA Airways
Deal found 11/5$805
This lol.travel deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:10 amPMO - SFO
2 stops20h 32mMultiple Airlines
Sat 12/2711:14 amSFO - PMO
2 stops18h 16mMultiple Airlines
Deal found 11/5$882
This Mytrip deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:35 pmPMO - SFO
2 stops34h 10mMultiple Airlines
Thu 11/271:00 pmSFO - PMO
3 stops25h 35mMultiple Airlines
Deal found 11/6$938

Cheap flight deals from Sicily to San Francisco

Keep the following information in mind while searching for Sicily to San Francisco flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$617
(lol.travel)

One-way from

$421
(Mytrip)

Popular in

January

Cheapest in

March

Average price

$945
Provider with most accurate pricing for Catania Fontanarossa-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Catania Fontanarossa-San Francisco flights.
Search Deals
From Sicily to San Francisco
Search Deals
One-way flight from Sicily to San Francisco
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.

Fly from

Sicily

Fly to

San Francisco

Route

Depart

Return

Price

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Fri 11/21

2:25 pm-1:05 pm

1 stop31h 40m

San Francisco

Thu 11/27

3:05 pm-2:30 pm

1 stop14h 25m

$617

Reggio CalabriaSan Francisco

REG - SFO

REGSFO

Reggio Calabria Tito Menniti

Sat 11/22

6:10 am-1:05 pm

1 stop15h 55m

San Francisco

Wed 11/26

11:08 am-2:30 pm

2 stops18h 22m

$619

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sat 1/17

3:15 pm-5:47 pm

2 stops35h 32m

San Francisco

Sun 1/25

10:52 am-2:30 pm

2 stops18h 38m

$621

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Wed 4/1

6:00 am-4:58 pm

2 stops19h 58m

San Francisco

Mon 4/6

11:00 am-2:40 pm

2 stops18h 40m

$634

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Wed 4/1

9:30 pm-1:15 pm

1 stop24h 45m

San Francisco

Mon 4/6

10:23 am-2:40 pm

2 stops19h 17m

$659

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

1:55 pm-6:45 pm

1 stop37h 50m

San Francisco

Mon 3/9

11:59 pm-10:45 am

2 stops50h 46m

$667

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

6:10 am-1:05 pm

1 stop15h 55m

San Francisco

Mon 3/9

4:05 pm-2:30 pm

1 stop14h 25m

$691

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Thu 3/5

6:00 am-1:05 pm

1 stop16h 05m

San Francisco

Mon 3/9

4:05 pm-6:30 pm

1 stop18h 25m

$692

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Mon 2/2

8:40 pm-4:30 pm

1 stop28h 50m

San Francisco

Mon 2/9

5:25 pm-8:40 pm

2 stops42h 15m

$700

Lamezia TermeSan Francisco

SUF - SFO

SUFSFO

Lamezia Terme Intl

Thu 3/5

6:15 am-1:05 pm

1 stop15h 50m

San Francisco

Mon 3/9

4:05 pm-11:00 pm

1 stop22h 55m

$700

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 23 results
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Best time to book a flight from Sicily to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sicily with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sicily to San Francisco

What is the cheapest month to book a flight from Sicily to San Francisco?

Currently, March is the cheapest month in which you can book a flight from Sicily to San Francisco (average of $481). Flying from Sicily to San Francisco in July is currently the most expensive (average of $794). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Sicily to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Sicily?

    For a flight from Sicily to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city.

  • How long is the flight from Sicily to San Francisco?

    A quick flight from Sicily to San Francisco can take about 31h 40m. ITA Airways provides one of the quickest options available for as low as $617. Airlines will cover a distance of 6478 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Sicily to San Francisco?

    The most popular flight routes from Sicily to San Francisco are Catania Fontanarossa - San Francisco, Palermo Punta Raisi - San Francisco and Reggio Calabria Tito Menniti - San Francisco.

  • Can I find deals for flights from Sicily to San Francisco that include hotel bookings?

    Yes. In addition to deals on Sicily to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sicily to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sicily to San Francisco.

  • Can I find deals for business class flights from Sicily to San Francisco?

    Yes. Cheapflights offers flight deals from Sicily to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sicily to San Francisco?

    Currently, March is the cheapest month in which you can book a flight from Sicily to San Francisco (average of $481). Flying from Sicily to San Francisco in July is currently the most expensive (average of $794). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Manteca
Watsonville
Sunnyvale
Santa Clara
Vallejo
Hollister
San Bruno
Foster City
Redwood City
Union City
Burlingame
Lodi
San Mateo
Vacaville
Lathrop

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Sicily to San Francisco

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Top airline flying from Sicily to San Francisco

Discover the top airline that operate flights from Sicily to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$710Average$990FlexibilityNo cancel feeOn-time76%

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