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$432+ Cheap flights from Sicily to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
CTA — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Sicily to San Francisco

Keep the following information in mind while searching for Sicily to San Francisco flight deals. Data was last updated September 11, 2025.

Round-trip from

$542
(SWISS)

One-way from

$432
(Mytrip)
From Sicily to San Francisco
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One-way flight from Sicily to San Francisco
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Find flight deals from Sicily to San Francisco

Cheapest flights from Sicily to San Francisco
Explore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This SWISS deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/218:35 pmCTA - SFO
1 stop29h 00mSWISS
Tue 10/288:25 pmSFO - CTA
1 stop16h 15mSWISS
Deal found 9/10$542
This lol.travel deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:15 pmCTA - SFO
1 stop27h 10mITA Airways
Tue 9/303:15 pmSFO - CTA
1 stop14h 25mITA Airways
Deal found 9/10$563
This lol.travel deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/158:30 pmPMO - SFO
1 stop25h 55mITA Airways
Tue 9/233:15 pmSFO - PMO
1 stop18h 05mITA Airways
Deal found 9/10$564
This lol.travel deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:25 amREG - SFO
1 stop16h 00mITA Airways
Tue 9/303:15 pmSFO - REG
1 stop14h 15mITA Airways
Deal found 9/10$599
This lol.travel deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:15 amSUF - SFO
1 stop16h 10mITA Airways
Tue 9/303:15 pmSFO - SUF
1 stop18h 15mITA Airways
Deal found 9/11$600
This oojo deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/29:30 pmCTA - SFO
1 stop24h 35mITA Airways
Sat 11/223:05 pmSFO - CTA
1 stop14h 35mITA Airways
Deal found 9/11$637
This SWISS deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:10 pmPMO - SFO
1 stop30h 20mSWISS
Sun 11/27:25 pmSFO - PMO
1 stop34h 05mSWISS
Deal found 9/11$711
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:25 pmCTA - SFO
1 stop24h 40mTurkish Airlines
Thu 2/121:10 pmSFO - CTA
1 stop34h 25mTurkish Airlines
Deal found 9/11$712
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/159:45 amPMO - SFO
2 stops24h 14mUnited Airlines
Tue 9/2311:59 pmSFO - PMO
2 stops22h 16mUnited Airlines
Deal found 9/11$736
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/259:25 amCTA - SFO
1 stop35h 40mTurkish Airlines
Sat 11/12:10 pmSFO - CTA
1 stop20h 15mTurkish Airlines
Deal found 9/10$744
This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/211:50 pmCTA - SFO
2 stops33h 45mMultiple Airlines
Tue 10/2810:15 amSFO - CTA
3 stops24h 45mMultiple Airlines
Deal found 9/10$748
This Lufthansa deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:25 pmPMO - SFO
1 stop34h 10mLufthansa
Sun 11/22:40 pmSFO - PMO
2 stops17h 15mLufthansa
Deal found 9/11$753

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.

Fly from

Sicily

Fly to

San Francisco

Route

Depart

Return

Price

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Tue 10/21

8:35 pm-4:35 pm

1 stop29h 00m

San Francisco

Tue 10/28

8:25 pm-8:40 pm

1 stop16h 15m

$542

Reggio CalabriaSan Francisco

REG - SFO

REGSFO

Reggio Calabria Tito Menniti

Fri 9/26

6:25 am-1:25 pm

1 stop16h 00m

San Francisco

Tue 9/30

3:15 pm-2:30 pm

1 stop14h 15m

$599

Lamezia TermeSan Francisco

SUF - SFO

SUFSFO

Lamezia Terme Intl

Fri 9/26

6:15 am-1:25 pm

1 stop16h 10m

San Francisco

Tue 9/30

3:15 pm-6:30 pm

1 stop18h 15m

$600

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

1:55 pm-6:45 pm

1 stop37h 50m

San Francisco

Mon 3/9

11:59 pm-10:45 am

2 stops50h 46m

$635

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Sun 11/2

9:30 pm-1:05 pm

1 stop24h 35m

San Francisco

Sat 11/22

3:05 pm-2:40 pm

1 stop14h 35m

$637

Reggio CalabriaSan Francisco

REG - SFO

REGSFO

Reggio Calabria Tito Menniti

Thu 3/5

6:25 am-1:05 pm

1 stop15h 40m

San Francisco

Mon 3/9

4:05 pm-2:30 pm

1 stop14h 25m

$659

Lamezia TermeSan Francisco

SUF - SFO

SUFSFO

Lamezia Terme Intl

Thu 3/5

6:15 am-1:05 pm

1 stop15h 50m

San Francisco

Mon 3/9

4:05 pm-6:30 pm

1 stop18h 25m

$664

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Thu 3/5

6:10 am-1:05 pm

1 stop15h 55m

San Francisco

Mon 3/9

4:05 pm-6:20 pm

1 stop18h 15m

$675

CataniaSan Francisco

CTA - SFO

CTASFO

Catania Fontanarossa

Thu 3/5

6:00 am-1:05 pm

1 stop16h 05m

San Francisco

Mon 3/9

4:05 pm-6:30 pm

1 stop18h 25m

$675

PalermoSan Francisco

PMO - SFO

PMOSFO

Palermo Punta Raisi

Sun 10/26

7:10 pm-5:30 pm

1 stop30h 20m

San Francisco

Sun 11/2

7:25 pm-2:30 pm

1 stop34h 05m

$711

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 38 results
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Best time to book a flight from Sicily to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sicily with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sicily to San Francisco

What is the cheapest month to book a flight from Sicily to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Sicily to San Francisco (average of $276). Flying from Sicily to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Sicily to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Sicily?

    For a flight from Sicily to San Francisco, you will be flying into San Francisco. San Francisco (SFO) is just 11.8 mi from the center of the city.

  • How long is the flight from Sicily to San Francisco?

    A quick flight from Sicily to San Francisco can take about 16h. SWISS provides one of the quickest options available for as low as $599. Airlines will cover a distance of 6559 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Sicily to San Francisco?

    The most popular flight routes from Sicily to San Francisco are Catania Fontanarossa - San Francisco, Palermo Punta Raisi - San Francisco and Lamezia Terme Intl - San Francisco.

  • Can I find deals for flights from Sicily to San Francisco that include hotel bookings?

    Yes. In addition to deals on Sicily to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sicily to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sicily to San Francisco.

  • Can I find deals for business class flights from Sicily to San Francisco?

    Yes. Cheapflights offers flight deals from Sicily to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sicily to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Sicily to San Francisco (average of $276). Flying from Sicily to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
Redwood City
Union City
San Leandro
San Mateo
Lathrop

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