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$206+ Cheap flights from Roanoke to San Francisco (ROA - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Roanoke to San Francisco are usually found in June or July, booked 89 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Roanoke to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$309
(American Airlines)

One-way from

$206
(Kiwi.com)

Popular in

January

Cheapest in

June

Average price

$442
From Roanoke to San Francisco
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One-way flight from Roanoke to San Francisco
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Highest demand for flights based on searches. 20% potential increase in price ($133 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:33 amROA - SFO
1 stop7h 53mAmerican Airlines
Mon 1/1912:27 amSFO - ROA
1 stop6h 58mAmerican Airlines
Deal found 9/10$309
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:30 amROA - SFO
1 stop9h 00mAmerican Airlines
Sat 11/1510:15 amSFO - ROA
2 stops10h 50mAmerican Airlines
Deal found 9/11$314
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1010:20 amROA - SFO
1 stop11h 14mUnited Airlines
Tue 1/611:56 pmSFO - ROA
1 stop7h 55mUnited Airlines
Deal found 9/9$325
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/812:43 pmROA - SFO
1 stop11h 01mAmerican Airlines
Mon 10/1310:15 pmSFO - ROA
1 stop8h 19mAmerican Airlines
Deal found 9/11$334
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:53 pmROA - SFO
1 stop8h 01mAmerican Airlines
Sun 11/1611:59 pmSFO - ROA
2 stops9h 03mAmerican Airlines
Deal found 9/10$339
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:45 amROA - SFO
1 stop8h 04mUnited Airlines
Mon 1/56:45 amSFO - ROA
1 stop9h 06mUnited Airlines
Deal found 9/9$355
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:24 pmROA - SFO
1 stop10h 22mAmerican Airlines
Sun 9/2810:50 pmSFO - ROA
1 stop8h 15mAmerican Airlines
Deal found 9/9$369
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:21 pmROA - SFO
2 stops9h 57mAmerican Airlines
Mon 9/296:30 amSFO - ROA
1 stop11h 00mAmerican Airlines
Deal found 9/9$374

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Roanoke

Fly to

San Francisco

Route

Depart

Return

Price

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Fri 11/14

6:20 am-11:29 am

1 stop8h 09m

San Francisco

Sun 11/16

11:44 pm-11:59 am

1 stop9h 15m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 11/8

6:20 am-11:29 am

1 stop8h 09m

San Francisco

Sat 11/15

5:10 am-4:56 pm

1 stop8h 46m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 11/8

2:47 pm-9:28 pm

2 stops9h 41m

San Francisco

Sat 11/15

6:15 pm-8:50 am

2 stops11h 35m

$319

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 12/10

10:20 am-6:34 pm

1 stop11h 14m

San Francisco

Tue 1/6

11:56 pm-10:51 am

1 stop7h 55m

$325

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 10/8

12:43 pm-8:44 pm

1 stop11h 01m

San Francisco

Mon 10/13

10:15 pm-9:34 am

1 stop8h 19m

$334

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sun 11/9

9:40 am-5:54 pm

1 stop11h 14m

San Francisco

Sat 11/15

10:15 am-12:05 am

2 stops10h 50m

$339

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 11/13

12:53 pm-8:14 pm

2 stops10h 21m

San Francisco

Sat 11/15

12:27 am-12:27 pm

1 stop9h 00m

$339

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 9/25

10:30 am-3:23 pm

1 stop7h 53m

San Francisco

Sun 9/28

11:00 pm-10:17 am

1 stop8h 17m

$369

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Mon 1/5

7:36 am-3:01 pm

1 stop10h 25m

San Francisco

Thu 1/22

9:34 am-8:11 pm

1 stop7h 37m

$374

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Fri 9/26

3:01 pm-9:50 pm

1 stop9h 49m

San Francisco

Tue 9/30

8:00 am-11:08 pm

2 stops12h 08m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 18 results
1
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Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Francisco. Price data was last updated on August 29, 2025.

Booking 89 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Roanoke to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $276). Flying from Roanoke to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SFO?

Find hourly flight availability from Roanoke to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from Roanoke to San Francisco by exploring options for tickets in the evening.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 11, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Roanoke to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to San Francisco?

    There are many flights that can get you from Roanoke to San Francisco in 8h 09m. Fly via United Airlines or American Airlines to get the fastest option. The distance from Roanoke to San Francisco is about 2303 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

    Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $282. Other airlines that can offer you cheap pricing are American Airlines, from $308, and United Airlines, from $308. Users have found that Delta is 46% cheaper than the other options available to this destination.

  • Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.

  • Can I find deals for business class flights from Roanoke to San Francisco?

    Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $276). Flying from Roanoke to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
Redwood City
Union City
San Leandro
San Mateo
Lathrop

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Top 3 airlines flying from Roanoke to San Francisco

Discover the top 3 airlines that operate flights from Roanoke to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$282Average$503FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$308Average$513FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$509FlexibilityNo cancel feeOn-time71%

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