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$204+ Cheap flights from Roanoke to San Francisco (ROA - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SFO
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Roanoke to San Francisco are usually found in October or June, booked 85 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Roanoke to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$309
(Delta)

One-way from

$204
(Kiwi.com)

Popular in

January

Cheapest in

October

Average price

$407
Provider with most accurate pricing for Roanoke-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-San Francisco flights.
Search Deals
From Roanoke to San Francisco
Search Deals
One-way flight from Roanoke to San Francisco
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($156 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($27 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:50 pmROA - SFO
1 stop8h 26mDelta
Sat 12/1310:30 pmSFO - ROA
1 stop9h 10mDelta
Deal found 10/28$309
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:30 amROA - SFO
2 stops11h 35mAmerican Airlines
Fri 12/1212:25 amSFO - ROA
1 stop7h 09mAmerican Airlines
Deal found 10/28$314
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:00 pmROA - SFO
1 stop9h 30mAmerican Airlines
Fri 11/1412:27 amSFO - ROA
1 stop9h 00mAmerican Airlines
Deal found 10/26$369
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:07 amROA - SFO
2 stops10h 26mAmerican Airlines
Sat 1/1711:35 pmSFO - ROA
1 stop7h 06mAmerican Airlines
Deal found 10/29$371
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:56 amROA - SFO
1 stop9h 58mAmerican Airlines
Mon 11/1711:18 pmSFO - ROA
2 stops11h 16mAmerican Airlines
Deal found 10/28$394
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/152:03 pmROA - SFO
1 stop11h 06mAmerican Airlines
Sun 1/1811:35 pmSFO - ROA
1 stop9h 34mAmerican Airlines
Deal found 10/28$400
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:50 pmROA - SFO
1 stop8h 26mDelta
Thu 12/182:00 pmSFO - ROA
1 stop7h 11mDelta
Deal found 10/28$408
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:20 amROA - SFO
1 stop8h 25mUnited Airlines
Mon 12/110:40 pmSFO - ROA
1 stop8h 26mUnited Airlines
Deal found 10/27$409

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Roanoke

Fly to

San Francisco

Route

Depart

Return

Price

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 12/6

6:00 am-12:25 pm

1 stop9h 25m

San Francisco

Thu 12/11

9:15 am-7:15 pm

1 stop7h 00m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 12/6

12:54 pm-5:51 pm

1 stop7h 57m

San Francisco

Wed 12/10

12:25 am-10:34 am

1 stop7h 09m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 12/6

3:50 pm-9:16 pm

1 stop8h 26m

San Francisco

Sat 12/13

10:30 pm-10:40 am

1 stop9h 10m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 12/17

6:07 am-1:33 pm

2 stops10h 26m

San Francisco

Sat 1/17

11:35 pm-9:41 am

1 stop7h 06m

$371

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 1/17

1:56 pm-10:06 pm

2 stops11h 10m

San Francisco

Sun 1/18

11:35 pm-12:09 pm

1 stop9h 34m

$405

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 11/19

10:28 am-3:35 pm

1 stop8h 07m

San Francisco

Thu 11/27

11:44 pm-11:59 am

1 stop9h 15m

$409

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sun 11/23

5:38 pm-11:59 pm

1 stop9h 21m

San Francisco

Thu 11/27

11:44 pm-11:59 am

1 stop9h 15m

$409

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 3/3

2:47 pm-9:06 pm

1 stop9h 19m

San Francisco

Sat 3/7

10:40 pm-8:34 am

1 stop6h 54m

$409

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 11/8

6:00 am-1:33 pm

1 stop10h 33m

San Francisco

Thu 11/13

1:48 pm-12:15 am

1 stop7h 27m

$419

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Mon 2/2

3:53 pm-10:34 pm

2 stops33h 41m

$204

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 19 results
1
2

Compare providers for flights from Roanoke to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Francisco in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Francisco. Price data was last updated on October 24, 2025.

Booking 29 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Roanoke to San Francisco?

Currently, November is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $218). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SFO?

Find hourly flight availability from Roanoke to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 26% on flights from Roanoke to San Francisco by exploring options for tickets in the evening.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated October 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Roanoke to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to San Francisco?

    There are many flights that can get you from Roanoke to San Francisco in 7h 57m. Fly via Delta or American Airlines to get the fastest option. The distance from Roanoke to San Francisco is about 2303 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

    Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $282. Other airlines that can offer you cheap pricing are American Airlines, from $308, and United Airlines, from $308. Users have found that Delta is 43% cheaper than the other options available to this destination.

  • Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.

  • Can I find deals for business class flights from Roanoke to San Francisco?

    Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $218). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
South San Francisco
Santa Cruz
Livermore
Turlock
Watsonville
Sunnyvale
Santa Clara
Antioch
Manteca
Vallejo
Hollister
Vacaville
San Bruno
Foster City
Redwood City
Union City
Fairfield
Burlingame
Lodi

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Top 3 airlines flying from Roanoke to San Francisco

Discover the top 3 airlines that operate flights from Roanoke to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$282Average$373FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$308Average$525FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$522FlexibilityNo cancel feeOn-time71%

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