San Francisco

$184+ Cheap flights from Roanoke to San Francisco (ROA - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SFO
أبريل 16 — أبريل 231
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Cheap flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on مارس 17, 2026.

This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ث 4/2812:58 pm
ROA
-
SFO
1 stop11h 21m
American Airlines
ث 5/510:35 pm
SFO
-
ROA
1 stop10h 58m
American Airlines
Deal found 3/13$349
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ث 4/288:50 am
ROA
-
SFO
2 stops9h 35m
American Airlines
ر 5/67:00 am
SFO
-
ROA
1 stop9h 05m
American Airlines
Deal found 3/12$354
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ث 4/72:55 pm
ROA
-
SFO
1 stop8h 55m
United Airlines
س 4/1110:38 pm
SFO
-
ROA
1 stop8h 11m
United Airlines
Deal found 3/13$369
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ر 4/2212:58 pm
ROA
-
SFO
1 stop11h 21m
American Airlines
س 4/2511:28 pm
SFO
-
ROA
2 stops10h 05m
American Airlines
Deal found 3/13$374
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ج 5/296:00 am
ROA
-
SFO
1 stop9h 58m
American Airlines
س 7/45:00 am
SFO
-
ROA
1 stop9h 37m
American Airlines
Deal found 3/17$389
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ر 6/36:00 am
ROA
-
SFO
1 stop8h 45m
Delta
ر 9/21:45 pm
SFO
-
ROA
1 stop7h 05m
Delta
Deal found 3/13$394
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ج 9/45:47 pm
ROA
-
SFO
1 stop9h 33m
United Airlines
ح 9/611:30 pm
SFO
-
ROA
1 stop7h 22m
United Airlines
Deal found 3/12$397
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ر 6/36:00 am
ROA
-
SFO
1 stop8h 45m
Delta
ح 8/301:45 pm
SFO
-
ROA
1 stop7h 05m
Delta
Deal found 3/13$419
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ث 4/147:59 pm
ROA
-
SFO
1 stop8h 18m
United Airlines
س 4/1812:45 am
SFO
-
ROA
1 stop9h 44m
United Airlines
Deal found 3/15$420
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ر 5/207:59 pm
ROA
-
SFO
1 stop8h 17m
United Airlines
ر 5/2711:05 pm
SFO
-
ROA
1 stop7h 37m
United Airlines
Deal found 3/15$422

Find flight deals from Roanoke to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated مارس 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(American Airlines)

One-way from

$184
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$498
Provider with most accurate pricing for Roanoke-San Francisco flight deals.
Provider most trusted by Cheapflights users for Roanoke-San Francisco flights.
From Roanoke to San Francisco
One-way flight from Roanoke to San Francisco
Highest demand for flights based on searches. 9% potential increase in price ($47 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated مارس 17, 2026.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ر 4/22

2:54 pm-9:28 pm

1 stop9h 34m

San Francisco

س 4/25

7:00 am-6:56 pm

1 stop8h 56m

$349
Quickest round-trip

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

خ 6/4

7:30 pm-12:46 am

1 stop8h 16m

San Francisco

ج 9/4

1:45 pm-11:50 pm

1 stop7h 05m

$394

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ج 9/4

5:47 pm-12:20 am

1 stop9h 33m

San Francisco

ح 9/6

11:30 pm-9:52 am

1 stop7h 22m

$397

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

خ 6/4

7:30 pm-12:46 am

1 stop8h 16m

San Francisco

ح 8/30

1:45 pm-11:50 pm

1 stop7h 05m

$419

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ج 6/5

7:30 pm-8:21 am

2 stops15h 51m

San Francisco

س 8/29

1:45 pm-11:50 pm

1 stop7h 05m

$466

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ث 4/28

7:59 pm-1:17 am

1 stop8h 18m

San Francisco

س 5/2

11:05 pm-9:57 am

1 stop7h 52m

$469

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

س 4/18

5:45 pm-10:45 pm

1 stop8h 00m

San Francisco

س 4/25

9:30 pm-9:49 am

1 stop9h 19m

$469

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ر 8/5

6:00 am-11:45 am

1 stop8h 45m

San Francisco

ن 8/10

1:45 pm-11:50 pm

1 stop7h 05m

$469

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ج 5/15

7:59 pm-1:16 am

1 stop8h 17m

San Francisco

ر 5/20

10:55 pm-9:46 am

1 stop7h 51m

$575
Cheapest one-way

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ن 5/4

3:09 pm-10:41 am

3 stops46h 32m

$202

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Compare providers for flights from Roanoke to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Francisco in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Francisco. Price data was last updated on March 13, 2026.

Booking 29 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Roanoke to San Francisco?

Currently, November is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $218). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated مارس 17, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Roanoke to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.8

Food

7.2

Comfort

7.9

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Roanoke to San Francisco?

    There are many flights that can get you from Roanoke to San Francisco in 8h 16m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. The distance from Roanoke to San Francisco is about 2303 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

    Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $282. Other airlines that can offer you cheap pricing are American Airlines, from $308, and United Airlines, from $308. Users have found that Delta is 38% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Roanoke to San Francisco one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $124. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Roanoke to San Francisco for a low price.

  • Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.

  • Can I find deals for business class flights from Roanoke to San Francisco?

    Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $218). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Livermore
Roseville
Watsonville
Rancho Cordova
San Bruno
San Ramon
Sunnyvale
Vacaville
San Carlos
Redwood City
Turlock
San Lorenzo
Davis
Manteca
Union City
Elk Grove
Rohnert Park

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Roanoke to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Roanoke to San Francisco

Discover the top 3 airlines that operate flights from Roanoke to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated مارس 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$282Average$383FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$308Average$461FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$462FlexibilityNo cancel feeOn-time71%

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