San Francisco

$309+ Cheap flights from Roanoke to San Francisco (ROA - SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SFO
fev 27 — mar 61
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1. Tell us where you want to go

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Cheap flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on janeiro 28, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 4/67:59 pm
ROA
-
SFO
1 stop8h 18m
United Airlines
sex 4/1711:52 pm
SFO
-
ROA
1 stop7h 21m
United Airlines
Deal found 1/27$309
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 2/247:15 am
ROA
-
SFO
2 stops12h 39m
American Airlines
sáb 2/2810:36 am
SFO
-
ROA
1 stop10h 16m
American Airlines
Deal found 1/27$314
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 2/185:00 am
ROA
-
SFO
2 stops12h 12m
American Airlines
seg 2/2311:30 pm
SFO
-
ROA
2 stops9h 04m
American Airlines
Deal found 1/28$319
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 10/268:00 pm
ROA
-
SFO
1 stop8h 16m
United Airlines
dom 11/11:20 pm
SFO
-
ROA
1 stop7h 03m
United Airlines
Deal found 1/26$327
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 4/247:59 pm
ROA
-
SFO
1 stop8h 18m
United Airlines
qua 4/299:30 pm
SFO
-
ROA
1 stop9h 27m
United Airlines
Deal found 1/26$329
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 4/73:14 pm
ROA
-
SFO
1 stop8h 14m
Delta
seg 4/2010:35 pm
SFO
-
ROA
1 stop8h 53m
Delta
Deal found 1/26$349
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 3/256:00 am
ROA
-
SFO
1 stop9h 17m
American Airlines
ter 3/3111:29 pm
SFO
-
ROA
2 stops11h 58m
American Airlines
Deal found 1/26$354
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 4/67:51 pm
ROA
-
SFO
1 stop7h 44m
Delta
qua 4/156:00 am
SFO
-
ROA
2 stops15h 25m
Delta
Deal found 1/26$357
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 4/245:18 pm
ROA
-
SFO
2 stops9h 59m
American Airlines
qua 4/2911:35 pm
SFO
-
ROA
2 stops9h 58m
American Airlines
Deal found 1/26$360
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 4/57:51 pm
ROA
-
SFO
1 stop7h 44m
Delta
sáb 4/182:00 pm
SFO
-
ROA
1 stop7h 25m
Delta
Deal found 1/26$384
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 2/112:55 pm
ROA
-
SFO
1 stop9h 40m
United Airlines
seg 2/1610:50 pm
SFO
-
ROA
1 stop8h 18m
United Airlines
Deal found 1/28$389

Find flight deals from Roanoke to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated janeiro 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(Delta)

Popular in

December

Cheapest in

July

Average price

$422
Provider with most accurate pricing for Roanoke-San Francisco flight deals.
Provider most trusted by Cheapflights users for Roanoke-San Francisco flights.
From Roanoke to San Francisco
Highest demand for flights based on searches. 10% potential increase in price ($58 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in January 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janeiro 28, 2026.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Roanoke

Fly to

San Francisco

Route

Depart

Return

Price

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

seg 4/6

7:59 pm-1:17 am

1 stop8h 18m

San Francisco

sex 4/17

10:50 pm-10:13 am

1 stop8h 23m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ter 2/24

2:50 pm-10:20 pm

1 stop10h 30m

San Francisco

sáb 2/28

10:36 am-11:52 pm

1 stop10h 16m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

seg 4/6

7:51 pm-12:35 am

1 stop7h 44m

San Francisco

sáb 4/18

2:00 pm-12:25 am

1 stop7h 25m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

qua 3/25

5:35 pm-12:16 am

1 stop9h 41m

San Francisco

seg 3/30

10:50 pm-10:13 am

1 stop8h 23m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

sex 4/24

12:58 pm-9:19 pm

1 stop11h 21m

San Francisco

qua 4/29

11:35 pm-12:33 pm

2 stops9h 58m

$314

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ter 4/28

7:31 am-3:41 pm

2 stops11h 10m

San Francisco

qua 5/6

1:16 pm-11:39 pm

1 stop7h 23m

$314

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

sex 4/24

7:59 pm-1:17 am

1 stop8h 18m

San Francisco

qua 4/29

9:30 pm-9:57 am

1 stop9h 27m

$329

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

ter 4/7

3:14 pm-8:28 pm

1 stop8h 14m

San Francisco

ter 4/14

11:39 pm-10:28 am

1 stop7h 49m

$349

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

qua 4/8

11:08 am-5:36 pm

1 stop9h 28m

San Francisco

ter 4/14

10:35 pm-10:28 am

1 stop8h 53m

$349

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

sex 7/24

2:51 pm-10:53 pm

1 stop11h 02m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 16 results
1
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Compare providers for flights from Roanoke to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to San Francisco in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Francisco. Price data was last updated on January 23, 2026.

Booking 28 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Roanoke to San Francisco?

Currently, November is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $218). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated janeiro 28, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Roanoke to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Entertainment

7.8

Crew

8.5

Comfort

7.9

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Roanoke to San Francisco?

    There are many flights that can get you from Roanoke to San Francisco in 7h 44m. Fly via United Airlines, American Airlines, or Delta to get the fastest option. The distance from Roanoke to San Francisco is about 2303 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

    Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $282. Other airlines that can offer you cheap pricing are American Airlines, from $308, and United Airlines, from $308. Users have found that Delta is 40% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Roanoke to San Francisco one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $138. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Roanoke to San Francisco for a low price.

  • Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.

  • Can I find deals for business class flights from Roanoke to San Francisco?

    Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Francisco?

    Currently, November is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $218). Flying from Roanoke to San Francisco in December is currently the most expensive (average of $383). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Roseville
Santa Clara
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Manteca
Vallejo
San Lorenzo
Davis
Hollister
Redwood City
Union City

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Roanoke to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Roanoke to San Francisco

Discover the top 3 airlines that operate flights from Roanoke to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janeiro 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$282Average$338FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$308Average$488FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$498FlexibilityNo cancel feeOn-time71%

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