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$155+ Cheap flights from Roanoke to San Francisco (ROA - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — SFO
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheapflights Tip: The best prices from Roanoke to San Francisco are usually found in June or September, booked 44 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Roanoke to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$309
(American Airlines)

One-way from

$155
(United Airlines)

Popular in

January

Cheapest in

June

Average price

$602
From Roanoke to San Francisco
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One-way flight from Roanoke to San Francisco
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Highest demand for flights based on searches. 18% potential increase in price ($119 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Roanoke to San Francisco

Cheapest flights from Roanoke to San Francisco
Explore the most affordable flight options available from Roanoke to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:40 amROA - SFO
1 stop8h 49mAmerican Airlines
Mon 9/89:00 amSFO - ROA
1 stop8h 30mAmerican Airlines
Deal found 7/31$309
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amROA - SFO
1 stop10h 33mDelta
Sat 11/810:30 amSFO - ROA
2 stops10h 39mDelta
Deal found 7/30$367
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:20 amROA - SFO
1 stop8h 09mUnited Airlines
Sun 11/99:20 pmSFO - ROA
1 stop9h 27mUnited Airlines
Deal found 7/31$409

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Roanoke to San Francisco that are best for you.

Fly from

Roanoke

Fly to

San Francisco

Route

Depart

Return

Price

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 9/4

3:01 pm-9:50 pm

1 stop9h 49m

San Francisco

Mon 9/8

9:00 am-8:30 pm

1 stop8h 30m

$309

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Tue 8/26

6:45 am-1:35 pm

1 stop9h 50m

San Francisco

Tue 9/2

11:59 pm-10:06 am

1 stop7h 07m

$409

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Wed 8/6

6:00 am-10:12 am

1 stop7h 12m

San Francisco

Thu 8/21

1:41 pm-12:32 am

1 stop7h 51m

$524

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 8/21

6:20 am-11:13 am

1 stop7h 53m

$155

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Sat 9/27

11:15 am-11:29 pm

2 stops15h 14m

$296

RoanokeSan Francisco

ROA - SFO

ROASFO

Roanoke

Thu 8/21

4:07 pm-10:57 pm

2 stops9h 50m

$348

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Roanoke to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to San Francisco

How far ahead should I book a flight from Roanoke to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Roanoke to San Francisco. Price data was last updated on July 25, 2025.

Booking 43 days in advance of your planned departure date is, on average, the best time to get cheap flights from Roanoke to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Roanoke to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $276). Flying from Roanoke to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SFO?

Find hourly flight availability from Roanoke to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 27% on flights from Roanoke to San Francisco by exploring options for tickets in the evening.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 31, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Roanoke to San Francisco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Roanoke to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Roanoke to San Francisco round-trip?

    Cheapflights users have booked flights from Roanoke to San Francisco round-trip from $309. Other airlines that can offer you cheap pricing are United Airlines, from $409, and Delta, from $524. Users have found that American Airlines is 42% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Roanoke to San Francisco one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $155. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Roanoke to San Francisco for a low price.

  • Can I find deals for flights from Roanoke to San Francisco that include hotel bookings?

    Yes. In addition to deals on Roanoke to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to San Francisco.

  • Can I find deals for business class flights from Roanoke to San Francisco?

    Yes. Cheapflights offers flight deals from Roanoke to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Roanoke to San Francisco (average of $276). Flying from Roanoke to San Francisco in June is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Mountain View
Santa Cruz
South San Francisco
Livermore
Turlock
Manteca
Antioch
Hollister
Watsonville
Sunnyvale
Newark
Milpitas
Campbell
Foster City
Capitola
Santa Clara
San Leandro
Burlingame
Redwood City

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Top 3 airlines flying from Roanoke to San Francisco

Discover the top 3 airlines that operate flights from Roanoke to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$302Average$458FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$308Average$525FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$318Average$522FlexibilityNo cancel feeOn-time69%

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