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$346+ Cheap flights from Florence (FLR) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
FLR — SFO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Florence Peretola to San Francisco are usually found in September or January, booked 24 days in advance, depart on a Friday or Tuesday and return on a Tuesday

Cheap flight deals from Florence to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$464
(lol.travel)

One-way from

$346
(lol.travel)

Popular in

May

Cheapest in

September

Average price

$495
From Florence Peretola to San Francisco
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One-way flight from Florence Peretola to San Francisco
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Highest demand for flights based on searches. 9% potential increase in price ($76 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Florence to San Francisco

Cheapest flights from Florence to San Francisco
Explore the most affordable flight options available from Florence to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This lol.travel deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:15 pmFLR - SFO
1 stop27h 20mTAP AIR PORTUGAL
Wed 10/295:35 pmSFO - FLR
1 stop16h 55mTAP AIR PORTUGAL
Deal found 9/11$464
This SWISS deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SWISS is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:05 amFLR - SFO
1 stop19h 05mSWISS
Wed 10/298:25 pmSFO - FLR
1 stop28h 25mSWISS
Deal found 9/10$531
This lastminute.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:30 amFLR - SFO
1 stop15h 35mITA Airways
Thu 11/133:05 pmSFO - FLR
1 stop14h 40mITA Airways
Deal found 9/11$585
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:00 pmFLR - SFO
1 stop27h 50mKLM
Sun 11/303:40 pmSFO - FLR
1 stop13h 45mKLM
Deal found 9/11$658
This lastminute.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/63:20 pmFLR - SFO
1 stop32h 40mBritish Airways
Thu 11/1312:49 pmSFO - FLR
2 stops36h 21mBritish Airways
Deal found 9/11$665
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:30 amFLR - SFO
1 stop14h 15mDelta
Wed 10/2911:58 amSFO - FLR
2 stops18h 27mDelta
Deal found 9/11$670
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:40 amFLR - SFO
1 stop14h 10mDelta
Sun 11/306:00 amSFO - FLR
2 stops20h 20mDelta
Deal found 9/9$672

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Florence to San Francisco that are best for you.

Fly from

Florence

Fly to

San Francisco

Route

Depart

Return

Price

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Mon 10/20

7:15 pm-1:35 pm

1 stop27h 20m

San Francisco

Wed 10/29

5:35 pm-6:30 pm

1 stop16h 55m

$464

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Mon 10/20

6:05 am-4:10 pm

1 stop19h 05m

San Francisco

Wed 10/29

8:25 pm-8:50 am

1 stop28h 25m

$531

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Mon 11/24

12:20 pm-11:50 am

1 stop32h 30m

San Francisco

Sun 11/30

3:40 pm-10:55 pm

1 stop22h 15m

$660

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Thu 11/6

3:20 pm-3:00 pm

1 stop32h 40m

San Francisco

Thu 11/13

12:49 pm-10:10 am

2 stops36h 21m

$665

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Thu 10/23

6:30 am-11:45 am

1 stop14h 15m

San Francisco

Wed 10/29

11:58 am-2:25 pm

2 stops18h 27m

$670

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Mon 11/24

6:40 am-11:50 am

1 stop14h 10m

San Francisco

Sun 11/30

10:30 am-2:25 pm

2 stops18h 55m

$670

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Mon 10/20

7:15 pm-1:35 pm

1 stop27h 20m

$346

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Thu 11/13

7:15 pm-4:05 pm

1 stop29h 50m

$351

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Sun 11/9

7:15 pm-2:35 pm

1 stop28h 20m

$352

FlorenceSan Francisco

FLR - SFO

FLRSFO

Florence Peretola

Wed 9/24

12:05 pm-2:30 pm

1 stop35h 25m

$356

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 16 results
1
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Best time to book a flight from Florence to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to San Francisco

How far ahead should I book a flight from Florence to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Florence to San Francisco. Price data was last updated on August 29, 2025.

Booking 24 days in advance of your planned departure date is, on average, the best time to get cheap flights from Florence to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Florence to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Florence to San Francisco (average of $276). Flying from Florence to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FLR to SFO?

Find hourly flight availability from Florence to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Florence to San Francisco is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 10% on airfare.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with United Airlines, Lufthansa, and ITA Airways from Florence to San Francisco by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Lufthansa
6.8
Okay
7,409 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
ITA Airways
6.7
Okay
1,036 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Florence to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence to San Francisco?

    Airlines like TAP AIR PORTUGAL and SWISS fly from Florence to San Francisco in about 19h 05m. The time it takes to get you to your destination can typically vary by up to 8h 15m. The distance between Florence and San Francisco is about 6101 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Florence to San Francisco round-trip?

    Currently priced at $535, United Airlines will fly you from Florence to San Francisco and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from ITA Airways and Lufthansa - these airlines can fly you to your destination from $546 and $554, respectively. These flights start at 26% lower than the current average price 3 months from now.

  • Can I find deals for flights from Florence to San Francisco that include hotel bookings?

    Yes. In addition to deals on Florence to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to San Francisco.

  • Can I find deals for business class flights from Florence to San Francisco?

    Yes. Cheapflights offers flight deals from Florence to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Florence to San Francisco (average of $276). Flying from Florence to San Francisco in June is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Roseville
Santa Cruz
Livermore
South San Francisco
Turlock
Antioch
Watsonville
Manteca
Santa Clara
Sunnyvale
Hollister
Vacaville
Foster City
Vallejo
Burlingame
Redwood City
Union City
San Leandro
San Mateo
Lathrop

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Top 3 airlines flying from Florence to San Francisco

Discover the top 3 airlines that operate flights from Florence to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$535Average$714FlexibilityNo cancel feeOn-time69%
ITA AirwaysCheapest$546Average$888FlexibilityNo cancel feeOn-time81%
LufthansaCheapest$554Average$790FlexibilityNo cancel feeOn-time76%

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