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$241+ Cheap flights from Grand Cayman to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
feb. 20 — feb. 271
vie. 2/20
vie. 2/27
1 adult, Economy
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Cheap flight deals from Grand Cayman to San Diego

Cheapest flights from Grand Cayman to San Diego
Explore the most affordable flight options available from Grand Cayman to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2026.

This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/3012:45 pm
GCM
-
SAN
1 stop12h 25m
Delta
lun. 5/410:30 pm
SAN
-
GCM
1 stop10h 54m
Delta
Deal found 1/20$376
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/302:10 pm
GCM
-
SAN
2 stops20h 05m
American Airlines
lun. 5/410:45 pm
SAN
-
GCM
1 stop10h 50m
American Airlines
Deal found 1/21$390
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/73:40 pm
GCM
-
SAN
1 stop21h 59m
JetBlue
sáb. 3/149:05 pm
SAN
-
GCM
1 stop14h 30m
JetBlue
Deal found 1/21$498
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/72:25 pm
GCM
-
SAN
1 stop8h 53m
United Airlines
sáb. 3/1411:03 am
SAN
-
GCM
2 stops23h 42m
United Airlines
Deal found 1/21$508

Find flight deals from Grand Cayman to San Diego

Keep the following information in mind while searching for Grand Cayman to San Diego flight deals. Data was last updated enero 21, 2026.

Round-trip from

$376
(Delta)

One-way from

$241
(Delta)
From Grand Cayman to San Diego
Search Deals
One-way flight from Grand Cayman to San Diego
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Grand Cayman to San Diego that are best for you.

Fly from

Grand Cayman

Fly to

San Diego

Route

Depart

Return

Price

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

jue. 4/30

12:45 pm-11:10 pm

1 stop12h 25m

San Diego

lun. 5/4

10:30 pm-11:24 am

1 stop10h 54m

$376

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

jue. 4/30

1:35 pm-10:09 am

2 stops22h 34m

San Diego

lun. 5/4

3:04 pm-12:30 pm

1 stop19h 26m

$376

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

jue. 4/30

2:10 pm-8:15 am

2 stops20h 05m

San Diego

lun. 5/4

7:20 pm-11:35 am

2 stops14h 15m

$390

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

sáb. 3/7

3:40 pm-10:39 am

1 stop21h 59m

San Diego

sáb. 3/14

9:05 pm-1:35 pm

1 stop14h 30m

$498

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

sáb. 3/7

2:50 pm-7:40 am

2 stops19h 50m

San Diego

sáb. 3/14

11:03 am-12:45 pm

2 stops23h 42m

$508

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mié. 4/15

12:45 pm-11:10 pm

1 stop12h 25m

$241

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mar. 4/14

12:45 pm-8:47 pm

1 stop10h 02m

$241

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mar. 4/14

2:10 pm-10:09 am

2 stops21h 59m

$255

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mié. 4/15

2:10 pm-8:38 am

2 stops20h 28m

$255

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

lun. 4/13

1:50 pm-3:39 pm

2 stops27h 49m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 13 results
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Best time to book a flight from Grand Cayman to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated enero 21, 2026.
Read through reviews of airlines operating flights from Grand Cayman to San Diego, such as American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,169 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,169 reviews
American Airlines
7.2
Good
11,169 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Grand Cayman?

    San Diego (SAN) is the airport you will fly into if you book a flight from Grand Cayman to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Grand Cayman to San Diego?

    A quick flight from Grand Cayman to San Diego can take about 12h 25m. Delta provides one of the quickest options available for as low as $376. The distance between Grand Cayman and San Diego is about 2395 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Grand Cayman to San Diego that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Diego.

  • Can I find deals for business class flights from Grand Cayman to San Diego?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
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Julian
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Alternative routes for Grand Cayman to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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George Town to San Diego flights

Top airline flying from Grand Cayman to San Diego

Discover the top airline that operate flights from Grand Cayman to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$645FlexibilityNo cancel feeOn-time71%

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