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$343+ Cheap flights from Grand Cayman to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Grand Cayman to San Diego

Keep the following information in mind while searching for Grand Cayman to San Diego flight deals. Data was last updated January 15, 2026.

Round-trip from

$508
(United Airlines)

One-way from

$343
(Kiwi.com)
From Grand Cayman to San Diego
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One-way flight from Grand Cayman to San Diego
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Find flight deals from Grand Cayman to San Diego

Cheapest flights from Grand Cayman to San Diego
Explore the most affordable flight options available from Grand Cayman to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:45 pm
GCM
-
SAN
1 stop25h 53m
United Airlines
Sat 3/710:30 pm
SAN
-
GCM
1 stop11h 15m
United Airlines
Deal found 1/14$508
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/272:25 pm
GCM
-
SAN
2 stops21h 55m
United Airlines
Mon 2/24:10 pm
SAN
-
GCM
2 stops18h 05m
United Airlines
Deal found 1/15$1,988
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2612:40 pm
GCM
-
SAN
1 stop25h 52m
Multiple Airlines
Mon 2/27:51 am
SAN
-
GCM
2 stops47h 34m
Multiple Airlines
Deal found 1/15$3,960
This Gotogate deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/261:30 pm
GCM
-
SAN
2 stops37h 45m
Air Canada
Mon 2/212:45 pm
SAN
-
GCM
2 stops20h 40m
Air Canada
Deal found 1/15$4,381
This Air Canada deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/271:30 pm
GCM
-
SAN
1 stop25h 23m
Air Canada
Mon 2/212:40 pm
SAN
-
GCM
1 stop20h 45m
Air Canada
Deal found 1/15$5,157

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Grand Cayman to San Diego that are best for you.

Fly from

Grand Cayman

Fly to

San Diego

Route

Depart

Return

Price

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 2/28

5:45 pm-4:38 pm

1 stop25h 53m

San Diego

Sat 3/7

10:30 pm-12:45 pm

1 stop11h 15m

$508

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 1/27

2:25 pm-9:20 am

2 stops21h 55m

San Diego

Mon 2/2

4:10 pm-1:15 pm

2 stops18h 05m

$1,988

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Mon 1/26

12:40 pm-11:32 am

1 stop25h 52m

San Diego

Mon 2/2

7:51 am-10:25 am

2 stops47h 34m

$3,960

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Mon 1/26

1:30 pm-12:15 am

2 stops37h 45m

San Diego

Mon 2/2

12:45 pm-12:25 pm

2 stops20h 40m

$4,381

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 1/27

1:30 pm-11:53 am

1 stop25h 23m

San Diego

Mon 2/2

12:40 pm-12:25 pm

1 stop20h 45m

$5,157

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 1/25

2:49 pm-11:31 pm

3 stops59h 42m

$343

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 1/24

2:34 pm-12:08 am

3 stops36h 34m

$369

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 1/24

12:45 pm-10:32 pm

1 stop12h 47m

$429

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 1/25

2:50 pm-8:49 pm

2 stops32h 59m

$429

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 1/25

2:05 pm-8:37 pm

1 stop9h 32m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Best time to book a flight from Grand Cayman to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from Grand Cayman to San Diego, such as American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,136 reviews

Comfort

7.2

Overall

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,136 reviews
American Airlines
7.2
Good
11,136 reviews

Comfort

7.2

Overall

7.2

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Grand Cayman?

    San Diego (SAN) is the airport you will fly into if you book a flight from Grand Cayman to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Grand Cayman to San Diego?

    A quick flight from Grand Cayman to San Diego can take about 25h 53m. United Airlines provides one of the quickest options available for as low as $508. The distance between Grand Cayman and San Diego is about 2395 mi.

  • Can I find deals for flights from Grand Cayman to San Diego that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Diego.

  • Can I find deals for business class flights from Grand Cayman to San Diego?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
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Poway
Julian
Lemon Grove

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Alternative routes for Grand Cayman to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Grand Cayman to San Diego

Discover the top airline that operate flights from Grand Cayman to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$645FlexibilityNo cancel feeOn-time71%

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