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$251+ Cheap flights from Grand Cayman to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
Apr 10 — Apr 171
Fri 4/10
Fri 4/17
1 adult, Economy
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Cheap flight deals from Grand Cayman to San Diego

Cheapest flights from Grand Cayman to San Diego
Explore the most affordable flight options available from Grand Cayman to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.

This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:03 pm
GCM
-
SAN
2 stops18h 12m
American Airlines
Sat 5/29:45 pm
SAN
-
GCM
1 stop11h 46m
American Airlines
Deal found 3/10$565
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:20 pm
GCM
-
SAN
2 stops20h 48m
American Airlines
Sat 10/32:48 pm
SAN
-
GCM
2 stops18h 02m
American Airlines
Deal found 3/6$571
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1312:00 pm
GCM
-
SAN
1 stop12h 59m
American Airlines
Mon 3/1610:30 pm
SAN
-
GCM
1 stop10h 35m
American Airlines
Deal found 3/7$674
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:12 pm
GCM
-
SAN
1 stop11h 57m
Delta
Mon 3/169:55 pm
SAN
-
GCM
1 stop11h 52m
Delta
Deal found 3/10$722
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:25 pm
GCM
-
SAN
2 stops21h 15m
United Airlines
Mon 3/162:11 pm
SAN
-
GCM
1 stop20h 34m
United Airlines
Deal found 3/6$813

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Grand Cayman to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 4/25

4:03 pm-8:15 am

2 stops18h 12m

San Diego

Sat 5/2

9:45 pm-11:31 am

1 stop11h 46m

$565
Cheapest one-way

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 5/19

1:19 pm-11:27 pm

1 stop12h 08m

$251

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 5/29

12:33 pm-9:48 pm

1 stop11h 15m

$258

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 5/28

1:05 pm-10:35 pm

2 stops11h 30m

$263

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Mon 5/18

1:19 pm-11:27 pm

1 stop12h 08m

$266

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Mon 5/18

2:10 pm-8:38 am

2 stops20h 28m

$280
Quickest one-way

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 6/5

1:19 pm-9:15 pm

1 stop9h 56m

$283

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 5/31

12:50 pm-11:25 pm

2 stops12h 35m

$386

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 5/29

5:05 pm-11:26 pm

3 stops32h 21m

$414

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 4/11

1:15 pm-12:02 am

3 stops36h 47m

$420

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 11 resultsSorted by cheapest first
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2

Best time to book a flight from Grand Cayman to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 11, 2026.
Read through reviews of airlines operating flights from Grand Cayman to San Diego, such as American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,419 reviews

Food

6.4

Boarding

7.5

Overall

7.1

Entertainment

6.9

Crew

7.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,419 reviews
American Airlines
7.1
Good
11,419 reviews

Food

6.4

Boarding

7.5

Overall

7.1

Entertainment

6.9

Crew

7.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Grand Cayman?

    San Diego (SAN) is the airport you will fly into if you book a flight from Grand Cayman to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Grand Cayman to San Diego?

    A quick flight from Grand Cayman to San Diego can take about 18h 12m. American Airlines provides one of the quickest options available for as low as $565. The distance between Grand Cayman and San Diego is about 2395 mi.

  • Can I find deals for flights from Grand Cayman to San Diego that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Diego.

  • Can I find deals for business class flights from Grand Cayman to San Diego?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Alternative routes for Grand Cayman to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
George Town to Los Angeles flights
George Town to Las Vegas flights

Top airline flying from Grand Cayman to San Diego

Discover the top airline that operate flights from Grand Cayman to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$650FlexibilityNo cancel feeOn-time71%

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