San Diego

$296+ Cheap flights from Grand Cayman to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
Nov 26 — Dec 31
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Cheap flight deals from Grand Cayman to San Diego

Keep the following information in mind while searching for Grand Cayman to San Diego flight deals. Data was last updated October 27, 2025.

Round-trip from

$606
(American Airlines)

One-way from

$296
(United Airlines)
From Grand Cayman to San Diego
One-way flight from Grand Cayman to San Diego

Find flight deals from Grand Cayman to San Diego

Best flights from Grand Cayman to San Diego
Discover carefully curated flight deals from Grand Cayman to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:30 amGCM - SAN
1 stop11h 48mAmerican Airlines
Wed 3/1111:00 pmSAN - GCM
1 stop12h 20mAmerican Airlines
Deal found 10/24$606

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Grand Cayman to San Diego that are best for you.

Fly from

Grand Cayman

Fly to

San Diego

Route

Depart

Return

Price

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 3/10

8:30 am-6:18 pm

1 stop11h 48m

San Diego

Wed 3/11

11:00 pm-1:20 pm

1 stop12h 20m

$606

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Wed 4/1

1:35 pm-1:41 pm

2 stops26h 06m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 3/31

1:00 pm-11:11 pm

1 stop12h 11m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 3/31

1:35 pm-3:30 pm

2 stops27h 55m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 3/27

4:45 pm-8:17 pm

1 stop29h 32m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Mon 3/30

12:55 pm-10:48 pm

1 stop11h 53m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 4/2

3:35 pm-9:25 am

1 stop19h 50m

$350

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 3/29

2:55 pm-6:32 pm

1 stop29h 37m

$355

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 4/2

1:35 pm-8:16 pm

3 stops32h 41m

$424

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sun 11/30

2:50 pm-8:18 pm

2 stops56h 28m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Best time to book a flight from Grand Cayman to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 27, 2025.
Read through reviews of airlines operating flights from Grand Cayman to San Diego, such as American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Food

6.4

Crew

8.0

Boarding

7.5

Overall

7.2

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Diego from Grand Cayman?

    San Diego (SAN) is the airport you will fly into if you book a flight from Grand Cayman to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • How long is the flight from Grand Cayman to San Diego?

    A quick flight from Grand Cayman to San Diego can take about 11h 48m. American Airlines provides one of the quickest options available for as low as $606. The distance between Grand Cayman and San Diego is about 2395 mi.

  • Can I find deals for flights from Grand Cayman to San Diego that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Diego.

  • Can I find deals for business class flights from Grand Cayman to San Diego?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
Imperial Beach
National City

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Alternative routes for Grand Cayman to San Diego

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Grand Cayman to San Diego

Discover the top airline that operate flights from Grand Cayman to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$650FlexibilityNo cancel feeOn-time71%

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