San Diego

$298+ Cheap flights from Grand Cayman to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
May 21 — May 281
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Cheap flight deals from Grand Cayman to San Diego

One-way flights from Grand Cayman to San Diego
Search for one-way flight options from Grand Cayman to San Diego. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.

This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/91:35 pm
GCM
-
SAN
2 stops29h 44m
United Airlines
Deal found 4/17$298
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/94:03 pm
GCM
-
SAN
1 stop23h 11m
American Airlines
Deal found 4/17$310
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:50 am
GCM
-
SAN
3 stops25h 52m
Multiple Airlines
Deal found 4/17$374

Cheapflights Fare Finder

 
Customize your flight search to find flights from Grand Cayman to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Grand Cayman to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest one-way

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 5/9

1:35 pm-5:19 pm

2 stops29h 44m

$298
Quickest one-way

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 5/9

4:03 pm-1:14 pm

1 stop23h 11m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Sorted by cheapest first

Best time to book a flight from Grand Cayman to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Grand Cayman with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Grand Cayman to San Diego
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Grand Cayman to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Diego from Grand Cayman?

    San Diego (SAN) is the airport you will fly into if you book a flight from Grand Cayman to San Diego. It is only a 2.6 mi journey from San Diego (SAN) to San Diego’s city center.

  • Can I find deals for flights from Grand Cayman to San Diego that include hotel bookings?

    Yes. In addition to deals on Grand Cayman to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Grand Cayman to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Grand Cayman to San Diego.

  • Can I find deals for business class flights from Grand Cayman to San Diego?

    Yes. Cheapflights offers flight deals from Grand Cayman to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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