$369+ Cheap flights from Santo Domingo (SDQ) to San Antonio (SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — SAT
Sep 13 — Sep 201
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santo Domingo to San Antonio
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Cheapest flights from Santo Domingo to San AntonioExplore the most affordable flight options available from Santo Domingo to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
Explore the most affordable flight options available from Santo Domingo to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:30 am -
1 stop13h 33m
Tue 10/135:10 am -
1 stop7h 23m
Deal found 8/11![American Airlines logo]()
$670
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:21 am -
1 stop12h 42m
Thu 10/15:14 am -
1 stop6h 57m
Deal found 8/10![American Airlines logo]()
$672
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am -
2 stops29h 45m
Tue 10/135:30 pm -
2 stops19h 40m
Deal found 8/10![United Airlines logo]()
$675
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:51 pm -
1 stop9h 22m
Wed 1/65:10 am -
1 stop7h 00m
Deal found 8/10![American Airlines logo]()
$676
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:20 pm -
1 stop21h 21m
Sat 10/104:17 pm -
2 stops18h 38m
Deal found 8/9![United Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:21 am -
1 stop12h 42m
Wed 10/75:10 am -
1 stop9h 10m
Deal found 8/11![American Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:10 pm -
2 stops27h 43m
Wed 10/79:48 am -
2 stops25h 07m
Deal found 8/11![United Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
1 stop10h 12m
Fri 10/236:00 am -
1 stop15h 46m
Deal found 8/13![United Airlines logo]()
$753
Best flights from Santo Domingo to San AntonioDiscover carefully curated flight deals from Santo Domingo to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
Discover carefully curated flight deals from Santo Domingo to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:30 am -
1 stop13h 33m
Tue 10/135:10 am -
1 stop7h 23m
Deal found 8/12![American Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am -
2 stops29h 45m
Tue 10/134:17 pm -
2 stops20h 53m
Deal found 8/9![United Airlines logo]()
$675
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
2 stops27h 38m
Mon 10/1211:47 am -
2 stops25h 23m
Deal found 8/10![United Airlines logo]()
$675
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:51 pm -
1 stop9h 22m
Wed 1/65:10 am -
1 stop7h 00m
Deal found 8/10![American Airlines logo]()
$676
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:15 pm -
2 stops19h 36m
Thu 10/15:14 am -
1 stop9h 03m
Deal found 8/10![American Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:20 pm -
1 stop21h 21m
Sat 10/104:17 pm -
2 stops18h 38m
Deal found 8/9![United Airlines logo]()
$681
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:15 pm -
1 stop8h 48m
Sat 10/105:10 am -
1 stop9h 10m
Deal found 8/9![American Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
1 stop10h 12m
Fri 10/236:00 am -
1 stop15h 46m
Deal found 8/13![United Airlines logo]()
$753
Last-minute flights from Santo Domingo to San AntonioDiscover last-minute flight deals from Santo Domingo to San Antonio. Data last updated August 14, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to San Antonio. Data last updated August 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:27 am -
1 stop14h 32m
Fri 8/215:00 am -
2 stops12h 44m
Deal found 8/10![American Airlines logo]()
$937
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:30 am -
1 stop13h 33m
Tue 10/135:10 am -
1 stop7h 23m
Deal found 8/11![American Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:00 am -
2 stops29h 45m
Tue 10/135:30 pm -
2 stops19h 40m
Deal found 8/10![United Airlines logo]()
$675
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:21 am -
1 stop12h 42m
Thu 10/15:14 am -
1 stop6h 57m
Deal found 8/10![American Airlines logo]()
$672
This Mytrip deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:45 pm -
3 stops31h 35m
Thu 10/111:15 am -
2 stops17h 44m
Deal found 8/10![Multiple Airlines logo]()
$852
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:21 am -
1 stop12h 42m
Wed 10/75:10 am -
1 stop9h 10m
Deal found 8/11![American Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:10 pm -
2 stops27h 43m
Wed 10/79:48 am -
2 stops25h 07m
Deal found 8/11![United Airlines logo]()
$737
One-way flights from Santo Domingo to San AntonioSearch for one-way flight options from Santo Domingo to San Antonio. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
Search for one-way flight options from Santo Domingo to San Antonio. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/262:53 pm -
1 stop26h 37m
Deal found 8/9![United Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:00 pm -
2 stops43h 15m
Deal found 8/13![Multiple Airlines logo]()
$386
This Priceline deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:01 am -
1 stop26h 39m
Deal found 8/13![Aeromexico logo]()
$502
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:27 am -
1 stop12h 32m
Deal found 8/13![American Airlines logo]()
$508
Find flight deals from Santo Domingo to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $670 (American Airlines) |
One-way from | $369 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Santo Domingo to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Tue 9/15
9:30 am-10:03 pm
1 stop13h 33m
San Antonio
Tue 10/13
5:10 am-1:33 pm
1 stop7h 23m
$670
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Tue 9/15
6:00 am-10:45 am
2 stops29h 45m
San Antonio
Tue 10/13
4:17 pm-2:10 pm
2 stops20h 53m
$675
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Thu 10/8
6:00 am-8:38 am
2 stops27h 38m
San Antonio
Mon 10/12
11:47 am-2:10 pm
2 stops25h 23m
$675
Quickest round-trip
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Wed 12/23
3:51 pm-11:13 pm
1 stop9h 22m
San Antonio
Wed 1/6
5:10 am-2:10 pm
1 stop7h 00m
$676
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Thu 9/24
2:15 pm-8:51 am
2 stops19h 36m
San Antonio
Thu 10/1
5:14 am-3:17 pm
1 stop9h 03m
$677
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Thu 10/1
3:20 pm-11:41 am
1 stop21h 21m
San Antonio
Sat 10/10
4:17 pm-11:55 am
2 stops18h 38m
$681
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Thu 10/1
2:15 pm-10:03 pm
1 stop8h 48m
San Antonio
Sat 10/10
5:10 am-3:20 pm
1 stop9h 10m
$694
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Wed 10/21
6:00 am-3:12 pm
1 stop10h 12m
San Antonio
Fri 10/23
6:00 am-10:46 pm
1 stop15h 46m
$753
Cheapest one-way
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Tue 1/26
2:53 pm-3:30 pm
1 stop26h 37m
$369
Santo DomingoSan Antonio
SDQ Santo Domingo Las Americas - SAT San Antonio
SDQSAT
Santo Domingo Las Americas
Tue 9/1
4:00 pm-10:15 am
2 stops43h 15m
$386
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santo Domingo-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santo Domingo-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santo Domingo to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Santo Domingo with our price prediction graph.
SDQ-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated August 14, 2026.
Peruse reviews from past customers who have flown with American Airlines from Santo Domingo to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Crew
7.9
Food
6.4
Boarding
7.5
Entertainment
6.8
Overall
7.1
Reviews
1 / 20
10.0
ExcellentBeatriz,May 2026
HEL - DFW
Comfort
7.2
Crew
7.9
Food
6.4
Boarding
7.5
Entertainment
6.8
Overall
7.1
Reviews
1 / 20
10.0
ExcellentBeatriz,May 2026
HEL - DFW
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Santo Domingo and San Antonio flights
Browse other Santo Domingo and San Antonio flight options. Last updated on August 14, 2026.
Other flights from Santo Domingo
Browse through other flights departing from Santo Domingo. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
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Top airline flying from Santo Domingo to San Antonio
Discover the top airline that operate flights from Santo Domingo to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$531 | Average$531 | FlexibilityNo cancel fee | On-time71% |