HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Antonio

$324+ Cheap flights from Panama to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SAT
ene. 27 — feb. 31
mar. 1/27
mar. 2/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to San Antonio with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to San Antonio

Best flights from Panama to San Antonio
Discover carefully curated flight deals from Panama to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 28, 2025.

This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/184:41 pmPTY - SAT
1 stop7h 13mUnited Airlines
lun. 2/239:58 amSAT - PTY
1 stop6h 09mUnited Airlines
Deal found 12/25$516
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/182:40 pmPTY - SAT
1 stop10h 19mAmerican Airlines
lun. 2/233:08 pmSAT - PTY
2 stops21h 32mAmerican Airlines
Deal found 12/27$539
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/83:41 pmPTY - SAT
1 stop21h 33mUnited Airlines
jue. 3/125:00 amSAT - PTY
1 stop13h 38mUnited Airlines
Deal found 12/26$537
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/710:00 amPTY - SAT
1 stop9h 48mUnited Airlines
sáb. 4/117:40 amSAT - PTY
1 stop6h 34mUnited Airlines
Deal found 12/26$546
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/18:55 amPTY - SAT
1 stop9h 38mUnited Airlines
dom. 2/155:58 pmSAT - PTY
1 stop19h 47mUnited Airlines
Deal found 12/26$558

Find flight deals from Panama to San Antonio

Keep the following information in mind while searching for Panama to San Antonio flight deals. Data was last updated diciembre 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$516
(United Airlines)

One-way from

$324
(Kiwi.com)

Popular in

August

Cheapest in

April

Average price

$627
Provider with most accurate pricing for Panama City Tocumen Intl-San Antonio flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-San Antonio flights.
Search Deals
From Panama to San Antonio
Search Deals
One-way flight from Panama to San Antonio
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 28, 2025.
Use the filters below to find and compare flights from Panama to San Antonio that are best for you.

Fly from

Panama

Fly to

San Antonio

Route

Depart

Return

Price

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

mié. 2/18

4:41 pm-10:54 pm

1 stop7h 13m

San Antonio

lun. 2/23

9:58 am-5:07 pm

1 stop6h 09m

$516

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

dom. 3/8

3:41 pm-1:14 pm

1 stop21h 33m

San Antonio

jue. 3/12

5:00 am-6:38 pm

1 stop13h 38m

$537

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

mié. 2/18

2:40 pm-11:59 pm

1 stop10h 19m

San Antonio

lun. 2/23

3:08 pm-1:40 pm

2 stops21h 32m

$539

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

mar. 4/7

10:00 am-7:48 pm

1 stop9h 48m

San Antonio

sáb. 4/11

7:40 am-2:14 pm

1 stop6h 34m

$546

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

dom. 2/1

8:55 am-5:33 pm

1 stop9h 38m

San Antonio

dom. 2/15

5:58 pm-2:45 pm

1 stop19h 47m

$558

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

mar. 1/13

3:50 pm-8:14 am

3 stops41h 24m

$324

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

sáb. 3/14

7:55 am-3:33 pm

1 stop7h 38m

$338

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

dom. 1/11

4:41 pm-9:21 pm

1 stop29h 40m

$355

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

vie. 1/9

4:41 pm-5:33 pm

1 stop25h 52m

$355

Panama CitySan Antonio

PTY - SAT

PTYSAT

Panama City Tocumen Intl

vie. 1/9

11:25 am-9:55 am

2 stops23h 30m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 13 results
1
2

Best time to book a flight from Panama to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to San Antonio

What is the cheapest month to book a flight from Panama to San Antonio?

Currently, March is the cheapest month in which you can book a flight from Panama to San Antonio (average of $326). Flying from Panama to San Antonio in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated diciembre 28, 2025.
Read through reviews of airlines operating flights from Panama to San Antonio, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,113 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,113 reviews
United Airlines
7.4
Good
9,113 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Comfort

7.3

Overall

7.4

Food

6.6

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Panama to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Antonio from Panama?

    San Antonio (SAT), located 7.6 mi from the city center, is the airport you fly into when you book flights from Panama to San Antonio.

  • How long is the flight from Panama to San Antonio?

    Airlines like United Airlines and American Airlines fly from Panama to San Antonio in about 7h 13m. The time it takes to get you to your destination can typically vary by up to 3h 06m. Airlines will cover a distance of 1876 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to San Antonio that include hotel bookings?

    Yes. In addition to deals on Panama to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to San Antonio.

  • Can I find deals for business class flights from Panama to San Antonio?

    Yes. Cheapflights offers flight deals from Panama to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to San Antonio?

    Currently, March is the cheapest month in which you can book a flight from Panama to San Antonio (average of $326). Flying from Panama to San Antonio in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to San Antonio

See prices for flight routes from nearby airports that may be better suited for you.
San José to Hobby flights
San Salvador to Hobby flights
Guatemala City to Hobby flights
San José to George Bush Intcntl flights
San Pedro Sula to Hobby flights
San Salvador to George Bush Intcntl flights
San Pedro Sula to George Bush Intcntl flights
Guatemala City to George Bush Intcntl flights
San Salvador to Dallas/Fort Worth flights
San José to Dallas/Fort Worth flights
Guatemala City to Dallas/Fort Worth flights
Panama City to Hobby flights
Panama City to George Bush Intcntl flights
Panama City to Dallas/Fort Worth flights
San Pedro Sula to Dallas/Fort Worth flights
San José to Austin flights
Philip S.W.Goldson to Hobby flights
Guatemala City to Love Field flights
San José to Love Field flights
Philip S.W.Goldson to George Bush Intcntl flights
San Salvador to Love Field flights
San José to San Antonio flights
San Salvador to San Antonio flights
Guatemala City to Austin flights
San Salvador to Austin flights
Philip S.W.Goldson to Dallas/Fort Worth flights
Managua to George Bush Intcntl flights
Managua to Hobby flights
Panama City to Austin flights
Liberia to Hobby flights
Panama City to San Antonio flights
Liberia to Dallas/Fort Worth flights
Liberia to George Bush Intcntl flights
Guatemala City to San Antonio flights
Tegucigalpa to George Bush Intcntl flights
San Pedro Sula to Austin flights
Philip S.W.Goldson to Love Field flights
San José to Midland flights
San Pedro Sula to San Antonio flights
Managua to Dallas/Fort Worth flights
Philip S.W.Goldson to Austin flights
San José to McAllen flights
San José to El Paso flights
Coxen Hole to Hobby flights
Managua to Austin flights
Managua to San Antonio flights

Top airline flying from Panama to San Antonio

Discover the top airline that operate flights from Panama to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$524Average$646FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.