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$100+ Cheap flights from Iowa to San Antonio (SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Iowa to San Antonio

Keep the following information in mind while searching for Iowa to San Antonio flight deals. Data was last updated April 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$222
(American Airlines)

One-way from

$100
(American Airlines)

Popular in

March

Cheapest in

July

Average price

$372
Provider with most accurate pricing for Des Moines-San Antonio flight deals.
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Provider most trusted by Cheapflights users for Des Moines-San Antonio flights.
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From Iowa to San Antonio
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One-way flight from Iowa to San Antonio
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Iowa to San Antonio

Cheapest flights from Iowa to San Antonio
Explore the most affordable flight options available from Iowa to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/308:20 pmDSM - SAT
1 stop22h 31mFrontier
Thu 6/57:50 pmSAT - DSM
1 stop24h 03mFrontier
Deal found 4/29$238
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:00 amCID - SAT
1 stop7h 00mAmerican Airlines
Thu 6/126:00 amSAT - CID
1 stop4h 48mAmerican Airlines
Deal found 4/29$249
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:00 pmOMA - SAT
1 stop9h 18mDelta
Tue 9/165:20 amSAT - OMA
1 stop8h 05mDelta
Deal found 4/29$257
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/236:32 pmMLI - SAT
1 stop5h 18mAmerican Airlines
Sun 6/86:31 pmSAT - MLI
1 stop5h 11mAmerican Airlines
Deal found 4/29$259
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:15 pmMLI - SAT
1 stop7h 06mDelta
Sat 5/244:42 pmSAT - MLI
1 stop6h 15mDelta
Deal found 4/28$263
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/117:00 amDSM - SAT
1 stop4h 55mDelta
Wed 6/185:25 amSAT - DSM
1 stop5h 14mDelta
Deal found 4/27$271
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/256:25 amDSM - SAT
2 stops9h 05mSouthwest
Wed 6/254:45 pmSAT - DSM
1 stop6h 30mSouthwest
Deal found 4/28$276
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:14 pmCID - SAT
1 stop5h 53mUnited Airlines
Sun 11/165:45 amSAT - CID
1 stop7h 57mUnited Airlines
Deal found 4/28$283
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/302:43 pmDSM - SAT
2 stops14h 21mMultiple Airlines
Thu 6/51:52 pmSAT - DSM
1 stop18h 33mMultiple Airlines
Deal found 4/29$286
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/228:00 amDSM - SAT
1 stop8h 38mUnited Airlines
Tue 5/275:39 amSAT - DSM
1 stop5h 01mUnited Airlines
Deal found 4/28$287
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/17:40 pmOMA - SAT
1 stop4h 18mAmerican Airlines
Thu 6/56:00 amSAT - OMA
1 stop5h 28mAmerican Airlines
Deal found 4/29$288
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/133:56 pmMLI - SAT
1 stop7h 03mUnited Airlines
Sat 5/172:08 pmSAT - MLI
1 stop7h 26mUnited Airlines
Deal found 4/28$289

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Iowa to San Antonio that are best for you.

Fly from

Iowa

Fly to

San Antonio

Route

Depart

Return

Price

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 5/30

8:20 pm-6:51 pm

1 stop22h 31m

San Antonio

Thu 6/5

7:50 pm-7:53 pm

1 stop24h 03m

$238

Cedar RapidsSan Antonio

CID - SAT

CIDSAT

Cedar Rapids

Thu 6/5

6:00 am-1:00 pm

1 stop7h 00m

San Antonio

Thu 6/12

6:00 am-10:48 am

1 stop4h 48m

$249

OmahaSan Antonio

OMA - SAT

OMASAT

Omaha Eppley Airfield

Fri 9/12

2:00 pm-11:18 pm

1 stop9h 18m

San Antonio

Tue 9/16

5:20 am-1:25 pm

1 stop8h 05m

$257

MolineSan Antonio

MLI - SAT

MLISAT

Moline Quad-City

Fri 5/23

6:32 pm-11:50 pm

1 stop5h 18m

San Antonio

Sun 6/8

6:31 pm-11:42 pm

1 stop5h 11m

$259

MolineSan Antonio

MLI - SAT

MLISAT

Moline Quad-City

Sat 5/17

5:15 pm-12:21 am

1 stop7h 06m

San Antonio

Sat 5/24

4:42 pm-10:57 pm

1 stop6h 15m

$263

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 6/11

7:00 am-11:55 am

1 stop4h 55m

San Antonio

Wed 6/18

5:25 am-10:39 am

1 stop5h 14m

$271

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 6/25

6:25 am-3:30 pm

2 stops9h 05m

San Antonio

Wed 6/25

4:45 pm-11:15 pm

1 stop6h 30m

$276

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 5/30

2:43 pm-5:04 am

2 stops14h 21m

San Antonio

Thu 6/5

1:52 pm-8:25 am

1 stop18h 33m

$286

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Thu 5/22

8:00 am-4:38 pm

1 stop8h 38m

San Antonio

Tue 5/27

5:39 am-10:40 am

1 stop5h 01m

$287

OmahaSan Antonio

OMA - SAT

OMASAT

Omaha Eppley Airfield

Sun 6/1

7:40 pm-11:58 pm

1 stop4h 18m

San Antonio

Thu 6/5

6:00 am-11:28 am

1 stop5h 28m

$288

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 35 results
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Best time to book a flight from Iowa to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to San Antonio

What is the cheapest month to book a flight from Iowa to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Iowa to San Antonio (average of $295). Flying from Iowa to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SAT?

Find hourly flight availability from Iowa to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from Iowa to San Antonio, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in San Antonio by month

Plan your trip to San Antonio by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Antonio ranges from 1.6 - 3.7 inches per month. May is typically the wettest month, when rainfall can reach 3.7 in. December is typically the driest time to visit San Antonio when rainfall is around 1.6 in.

Temperature in San Antonio by month

Plan your trip to San Antonio by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Antonio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 30, 2025.
To help decide which airline to fly from Iowa to San Antonio, see what other customers have to say about Southwest, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Overall

8.0

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Overall

8.0

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Overall

8.0

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Overall

8.0

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Overall

8.0

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,284 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Overall

8.0

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Iowa to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Antonio from Iowa?

    If you book a flight to San Antonio from Iowa, you will be flying to San Antonio, which is the city’s only airport. San Antonio (SAT) is located 7.6 mi from the center of San Antonio.

  • What are the cheapest airlines to fly from Iowa to San Antonio one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $100. Delta flights start at $136 while deals on Frontier start at $161 one-way.

  • What are the most popular routes from Iowa to San Antonio?

    Most travelers choose Des Moines - San Antonio, Cedar Rapids - San Antonio or Omaha Eppley Airfield - San Antonio when deciding on the best route from Iowa to San Antonio.

  • Can I find deals for flights from Iowa to San Antonio that include hotel bookings?

    Yes. In addition to deals on Iowa to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to San Antonio.

  • Can I find deals for business class flights from Iowa to San Antonio?

    Yes. Cheapflights offers flight deals from Iowa to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Iowa to San Antonio (average of $295). Flying from Iowa to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
New Braunfels

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Alternative routes for Iowa to San Antonio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Iowa to San Antonio

Discover the top 5 airlines that operate flights from Iowa to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$107Average$189FlexibilityNo cancel feeOn-time62%
DeltaCheapest$216Average$346FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$226Average$377FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$413FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$331Average$396FlexibilityNo cancel feeOn-time63%

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