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$372+ Cheap flights from Panama City, FL (ECP) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — ROM
May 22 — May 291
Fri 5/22
Fri 5/29
1 adult, Economy
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Cheap flight deals from Panama City to Rome

Cheapest flights from Panama City to Rome
Explore the most affordable flight options available from Panama City to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.

This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:10 am
ECP
-
FCO
2 stops16h 45m
United Airlines
Fri 11/131:30 pm
FCO
-
ECP
2 stops27h 07m
United Airlines
Deal found 4/18$917
This KLM deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:23 am
ECP
-
FCO
1 stop15h 52m
KLM
Fri 11/1310:25 am
FCO
-
ECP
1 stop14h 25m
KLM
Deal found 4/18$918
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:25 am
ECP
-
FCO
1 stop14h 20m
United Airlines
Sun 11/291:30 pm
FCO
-
ECP
2 stops27h 07m
United Airlines
Deal found 4/18$968
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:28 pm
ECP
-
FCO
2 stops20h 22m
United Airlines
Sat 9/129:45 am
FCO
-
ECP
2 stops32h 18m
United Airlines
Deal found 4/18$1,011
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:45 am
ECP
-
FCO
1 stop17h 30m
Delta
Sun 11/2910:25 am
FCO
-
ECP
1 stop14h 25m
Delta
Deal found 4/20$1,045
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2011:10 am
ECP
-
FCO
2 stops37h 35m
United Airlines
Sun 11/2912:15 pm
FCO
-
ECP
2 stops52h 22m
United Airlines
Deal found 4/20$1,049
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
ECP
-
FCO
2 stops18h 45m
United Airlines
Mon 5/1110:00 am
FCO
-
ECP
2 stops43h 05m
United Airlines
Deal found 4/18$1,110
This KLM deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:01 am
ECP
-
FCO
1 stop13h 34m
KLM
Mon 5/119:45 am
FCO
-
ECP
1 stop16h 24m
KLM
Deal found 4/18$1,145
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/197:46 am
ECP
-
FCO
1 stop16h 49m
Delta
Wed 7/291:10 pm
FCO
-
ECP
1 stop26h 10m
Delta
Deal found 4/20$1,158

Find flight deals from Panama City to Rome

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Rome (ROM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$1,011
(United Airlines)

One-way from

$372
(KLM)

Popular in

May

Cheapest in

February

Average price

$1,206
Provider with most accurate pricing for Panama City NW Florida Beaches-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Rome (ROM) flights.
Search Deals
From Panama City NW Florida Beaches to Rome (ROM)
Search Deals
One-way flight from Panama City NW Florida Beaches to Rome (ROM)
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($298 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($52 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Panama City to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 7/6

2:05 pm-9:15 am

2 stops36h 10m

Rome Fiumicino

Sat 7/25

11:30 am-9:37 am

2 stops29h 07m

$1,185

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sat 7/4

6:30 am-8:15 am

2 stops42h 45m

Rome Fiumicino

Sat 7/25

12:25 pm-9:37 am

2 stops52h 12m

$1,188

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sun 6/7

5:08 pm-12:40 pm

1 stop12h 32m

Rome Fiumicino

Thu 6/18

6:30 am-11:44 pm

2 stops24h 14m

$1,235

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 6/9

1:31 pm-11:25 am

2 stops14h 54m

Rome Fiumicino

Tue 6/30

6:30 am-6:43 pm

2 stops19h 13m

$1,239

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Tue 6/2

5:29 pm-4:35 pm

2 stops16h 06m

Rome Fiumicino

Tue 6/9

6:30 am-11:44 pm

2 stops24h 14m

$1,240

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 6/8

9:19 am-11:00 am

2 stops18h 41m

Rome Fiumicino

Tue 6/16

9:45 am-11:44 pm

1 stop20h 59m

$1,240

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 6/8

6:41 pm-7:05 pm

2 stops17h 24m

Rome Fiumicino

Thu 6/18

1:10 pm-11:44 pm

1 stop17h 34m

$1,240
Quickest round-trip

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Mon 7/6

2:43 pm-10:50 am

1 stop13h 07m

Rome Fiumicino

Sat 7/25

9:45 am-6:50 pm

1 stop16h 05m

$1,305
Cheapest one-way

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sat 10/17

4:10 pm-7:35 am

1 stop32h 25m

$372

Panama CityRome

ECP - FCO

ECPFCO

Panama City NW Florida Beaches

Sat 10/17

2:40 pm-8:15 am

2 stops34h 35m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Panama City to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Rome in April.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Rome flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Rome flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Rome flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Rome flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Rome

What is the cheapest month to book a flight from Panama City, Florida to Rome?

Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Rome (average of $447). Flying from Panama City, Florida to Rome in May is currently the most expensive (average of $1,382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City, Florida to Rome?

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated April 22, 2026.
Get a feel of what it's like to fly with Delta,KLM, andAmerican Airlines from Panama City to Rome by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,433 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,433 reviews
Delta
7.9
Good
8,433 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
KLM
7.8
Good
1,505 reviews
Delta
7.9
Good
8,433 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.1
Good
11,649 reviews
Delta
7.9
Good
8,433 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Rome?

    Located just 16.0 mi from the city center, Panama City NW Florida Beaches is the airport most travelers will use when flying to Rome from Panama City. Booking flights from NW Florida Beaches (ECP) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 1 airline.

  • How long is the flight from Panama City, Florida to Rome?

    Airlines like United Airlines and Delta fly from Panama City, Florida to Rome in about 12h 32m. The time it takes to get you to your destination can typically vary by up to 23h 38m. There are 5228 mi between Panama City, Florida and Rome. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City, Florida to Rome round-trip?

    Our cheapest airline available from Panama City, Florida to Rome is Delta. Our recent data shows that you can find tickets from as low as $657 on this airline. This flight start at 28% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to Rome that include hotel bookings?

    Yes. In addition to deals on Panama City to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Rome?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Rome.

  • Can I find deals for business class flights from Panama City to Rome?

    Yes. Cheapflights offers flight deals from Panama City to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Rome?

    Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Rome (average of $447). Flying from Panama City, Florida to Rome in May is currently the most expensive (average of $1,382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Montepulciano
Santa Marinella

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Top airline flying from Panama City to Rome

Discover the top airline that operate flights from Panama City to Rome. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$657Average$1,485FlexibilityNo cancel feeOn-timeN/A

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