Travelers have found that booking a Monday departure is the best way to save up to 123% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.
To save up to 43% on this flight, we recommend booking at least 57 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Charleston to Rome from $619 1-2 weeks out and tickets from $731 for flights departing within the next 72 hours.
Unlike at noon, when flights are generally more expensive, you can save up to 25% on flights from Charleston to Rome by exploring options for tickets in the afternoon.