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Santiago de Querétaro

$216+ Cheap flights from Missouri to Santiago de Querétaro (QRO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — QRO
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Missouri to Santiago de Querétaro

Cheapest flights from Missouri to Santiago de Querétaro
Explore the most affordable flight options available from Missouri to Santiago de Querétaro. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:45 pmSTL - QRO
2 stops33h 10mUnited Airlines
Sun 12/286:00 amQRO - STL
1 stop15h 55mUnited Airlines
Deal found 12/16$781
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:54 amSTL - QRO
1 stop15h 47mAmerican Airlines
Wed 12/246:45 amQRO - STL
1 stop7h 24mAmerican Airlines
Deal found 12/17$929
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:30 amSTL - QRO
2 stops14h 47mDelta
Wed 12/246:03 amQRO - STL
2 stops10h 25mDelta
Deal found 12/16$1,092
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:45 pmSTL - QRO
2 stops33h 10mUnited Airlines
Wed 12/248:10 amQRO - STL
1 stop8h 36mUnited Airlines
Deal found 12/16$1,187
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:00 amSTL - QRO
1 stop16h 49mAmerican Airlines
Sat 1/36:45 amQRO - STL
1 stop12h 46mAmerican Airlines
Deal found 12/16$1,530
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:45 pmSTL - QRO
2 stops33h 10mUnited Airlines
Sat 1/36:00 amQRO - STL
2 stops16h 22mUnited Airlines
Deal found 12/17$1,632

Find flight deals from Missouri to Santiago de Querétaro

Keep the following information in mind while searching for Missouri to Santiago de Querétaro flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$489
(Delta)

One-way from

$216
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$1,155
Provider with most accurate pricing for Lambert-St Louis-Santiago de Querétaro flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Santiago de Querétaro flights.
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From Missouri to Santiago de Querétaro
Search Deals
One-way flight from Missouri to Santiago de Querétaro
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($54 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Santiago de Querétaro that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Santiago de Querétaro that are best for you.

Fly from

Missouri

Fly to

Santiago de Querétaro

Route

Depart

Return

Price

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Tue 3/10

6:10 am-8:31 pm

2 stops15h 21m

Santiago de Querétaro

Tue 3/17

6:03 am-8:52 am

2 stops25h 49m

$489

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Mon 3/9

6:00 am-11:54 pm

2 stops18h 54m

Santiago de Querétaro

Wed 3/11

12:00 pm-11:42 pm

2 stops10h 42m

$489

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Mon 3/9

7:10 am-11:54 pm

2 stops17h 44m

Santiago de Querétaro

Mon 3/16

2:04 pm-11:43 am

2 stops20h 39m

$494

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Sun 3/8

5:29 pm-1:07 pm

2 stops20h 38m

Santiago de Querétaro

Wed 3/11

8:55 am-9:10 pm

1 stop11h 15m

$494

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Sun 3/8

5:29 pm-1:07 pm

2 stops20h 38m

Santiago de Querétaro

Mon 3/16

8:55 am-5:53 pm

1 stop7h 58m

$494

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Tue 3/10

6:10 am-8:31 pm

2 stops15h 21m

Santiago de Querétaro

Mon 3/16

2:04 pm-11:43 am

2 stops20h 39m

$494

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Mon 3/9

10:02 am-5:27 pm

1 stop8h 25m

Santiago de Querétaro

Sat 3/14

8:55 am-11:42 pm

1 stop13h 47m

$509

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Sat 3/7

7:10 am-5:15 pm

1 stop10h 05m

Santiago de Querétaro

Thu 3/12

8:55 am-11:42 pm

1 stop13h 47m

$509

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Sun 3/8

7:10 am-5:27 pm

1 stop11h 17m

Santiago de Querétaro

Thu 3/12

8:55 am-11:42 pm

1 stop13h 47m

$509

St. LouisSantiago de Querétaro

STL - QRO

STLQRO

Lambert-St Louis

Sat 3/7

10:11 am-5:15 pm

1 stop7h 04m

Santiago de Querétaro

Wed 3/11

12:00 pm-11:42 pm

2 stops10h 42m

$509

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 13 results
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Best time to book a flight from Missouri to Santiago de Querétaro

Have a flexible travel schedule? Discover the best time to fly to Santiago de Querétaro from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santiago de Querétaro

What is the cheapest month to book a flight from Missouri to Santiago de Querétaro?

Currently, January is the cheapest month in which you can book a flight from Missouri to Santiago de Querétaro (average of $225). Flying from Missouri to Santiago de Querétaro in October is currently the most expensive (average of $560). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to QRO?

Find hourly flight availability from Missouri to Santiago de Querétaro. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Santiago de Querétaro in the evening. If you’re flexible enough to do this you can expect to save up to 51% on your trip compared to booking a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santiago de Querétaro. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de Querétaro from Missouri?

    If you book a flight to Santiago de Querétaro from Missouri, you will be flying to Queretaro, which is the city’s only airport. Santiago de Querétaro (QRO) is located 13.2 mi from the center of Santiago de Querétaro.

  • How long is the flight from Missouri to Santiago de Querétaro?

    A quick flight from Missouri to Santiago de Querétaro can take about 15h 21m. Delta provides one of the quickest options available for as low as $489. Missouri and Santiago de Querétaro are separated by a distance of 1381 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Santiago de Querétaro that include hotel bookings?

    Yes. In addition to deals on Missouri to Santiago de Querétaro flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santiago de Querétaro?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santiago de Querétaro.

  • Can I find deals for business class flights from Missouri to Santiago de Querétaro?

    Yes. Cheapflights offers flight deals from Missouri to Santiago de Querétaro by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Santiago de Querétaro?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Santiago de Querétaro (average of $225). Flying from Missouri to Santiago de Querétaro in October is currently the most expensive (average of $560). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Missouri to Santiago de Querétaro

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Missouri to Santiago de Querétaro

Discover the top 2 airlines that operate flights from Missouri to Santiago de Querétaro. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$391Average$725FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$513Average$670FlexibilityNo cancel feeOn-time69%

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