$92+ Cheap flights from Missouri to Puerto Rico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJU
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Puerto Rico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Puerto Rico
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Cheapest flights from Missouri to Puerto RicoExplore the most affordable flight options available from Missouri to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Missouri to Puerto Rico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:44 pm -
2 stops38h 11m
Thu 11/123:59 pm -
1 stop27h 41m
Deal found 9/22![Frontier logo]()
$195
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:44 pm -
2 stops26h 54m
Wed 11/187:15 am -
2 stops12h 25m
Deal found 9/22![Frontier logo]()
$207
This Mytrip deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:44 pm -
2 stops26h 44m
Tue 11/104:52 pm -
2 stops26h 48m
Deal found 9/23![Frontier logo]()
$218
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:44 pm -
2 stops19h 33m
Wed 11/1812:59 am -
2 stops19h 40m
Deal found 9/21![Frontier logo]()
$230
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
2 stops17h 56m
Wed 10/287:15 am -
2 stops11h 25m
Deal found 9/22![Frontier logo]()
$233
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:44 pm -
2 stops20h 32m
Sun 11/112:59 am -
2 stops18h 41m
Deal found 9/21![Frontier logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:46 am -
1 stop27h 33m
Fri 12/116:25 am -
1 stop11h 34m
Deal found 9/22![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:30 pm -
1 stop8h 23m
Tue 10/2012:59 am -
2 stops17h 41m
Deal found 9/18![Frontier logo]()
$255
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:13 pm -
1 stop27h 15m
Fri 12/45:01 am -
1 stop8h 16m
Deal found 9/20![Frontier logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:06 am -
1 stop28h 12m
Thu 10/227:00 am -
1 stop28h 06m
Deal found 9/19![Multiple Airlines logo]()
$271
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:13 pm -
1 stop5h 58m
Mon 12/75:01 am -
1 stop8h 16m
Deal found 9/19![Frontier logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/269:16 am -
1 stop29h 01m
Tue 11/103:59 pm -
2 stops29h 48m
Deal found 9/22![Multiple Airlines logo]()
$289
Best flights from Missouri to Puerto RicoDiscover carefully curated flight deals from Missouri to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Missouri to Puerto Rico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1111:40 am -
1 stop7h 40m
Tue 3/166:15 am -
1 stop9h 35m
Deal found 9/21![Delta logo]()
$386
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:26 pm -
1 stop6h 47m
Sat 11/213:17 pm -
1 stop8h 50m
Deal found 9/20![American Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:55 pm -
2 stops10h 00m
Thu 11/54:00 pm -
2 stops10h 15m
Deal found 9/18![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:59 am -
2 stops12h 51m
Wed 10/211:25 pm -
1 stop11h 19m
Deal found 9/18![United Airlines logo]()
$386
This Priceline deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/135:59 pm -
1 stop18h 01m
Sun 2/212:55 pm -
1 stop11h 09m
Deal found 9/19![Frontier logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:24 pm -
2 stops15h 56m
Fri 10/2312:41 pm -
1 stop10h 58m
Deal found 9/20![American Airlines logo]()
$386
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:35 pm -
1 stop7h 35m
Thu 10/296:00 am -
1 stop13h 20m
Deal found 9/23![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/95:28 pm -
2 stops10h 47m
Sat 1/167:40 am -
1 stop8h 25m
Deal found 9/18![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:00 am -
1 stop6h 31m
Sun 1/316:15 am -
1 stop10h 28m
Deal found 9/22![Delta logo]()
$396
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:35 pm -
1 stop7h 35m
Mon 10/198:50 pm -
1 stop13h 45m
Deal found 9/19![Southwest logo]()
$386
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/171:10 pm -
2 stops9h 45m
Wed 10/2112:40 pm -
2 stops10h 25m
Deal found 9/18![Southwest logo]()
$386
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:39 am -
1 stop15h 41m
Fri 10/303:51 pm -
1 stop7h 48m
Deal found 9/23![American Airlines logo]()
$426
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3010:15 am -
2 stops10h 45m
Tue 2/210:45 am -
2 stops9h 25m
Deal found 9/18![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/37:35 am -
2 stops11h 49m
Sat 2/137:45 am -
1 stop7h 55m
Deal found 9/21![United Airlines logo]()
$486
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am -
2 stops14h 22m
Fri 10/307:05 am -
2 stops11h 20m
Deal found 9/20![United Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/195:13 pm -
2 stops21h 03m
Thu 2/256:00 am -
2 stops13h 54m
Deal found 9/18![American Airlines logo]()
$506
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:35 am -
1 stop9h 43m
Sat 10/102:59 pm -
1 stop7h 20m
Deal found 9/21![Delta logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:16 am -
1 stop8h 20m
Fri 12/112:05 am -
2 stops16h 14m
Deal found 9/22![United Airlines logo]()
$486
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/267:55 pm -
1 stop11h 55m
Sat 3/66:10 am -
2 stops15h 00m
Deal found 9/20![Southwest logo]()
$447
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/185:13 pm -
2 stops22h 40m
Wed 2/247:00 am -
2 stops12h 54m
Deal found 9/18![American Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:45 am -
2 stops12h 51m
Wed 12/22:52 pm -
1 stop10h 43m
Deal found 9/20![United Airlines logo]()
$486
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/149:00 am -
1 stop10h 00m
Sun 2/285:15 pm -
1 stop8h 03m
Deal found 9/18![Delta logo]()
$596
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2212:03 pm -
1 stop10h 13m
Fri 3/56:50 am -
1 stop14h 15m
Deal found 9/20![American Airlines logo]()
$506
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:10 pm -
2 stops8h 40m
Mon 10/194:10 pm -
2 stops8h 45m
Deal found 9/18![Southwest logo]()
$465
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:45 am -
2 stops10h 37m
Sun 11/222:05 am -
2 stops12h 18m
Deal found 9/20![United Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/146:24 pm -
1 stop8h 36m
Tue 3/26:00 am -
2 stops13h 54m
Deal found 9/18![American Airlines logo]()
$506
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:05 pm -
1 stop7h 20m
Sat 10/101:20 pm -
1 stop9h 05m
Deal found 9/18![Southwest logo]()
$481
This Priceline deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:05 pm -
1 stop6h 47m
Thu 12/313:47 am -
1 stop22h 54m
Deal found 9/21![Frontier logo]()
$876
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:00 pm -
1 stop7h 22m
Wed 11/47:40 am -
1 stop8h 33m
Deal found 9/19![United Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/177:00 am -
1 stop8h 53m
Sat 2/276:00 am -
2 stops13h 54m
Deal found 9/20![American Airlines logo]()
$511
Last-minute flights from Missouri to Puerto RicoDiscover last-minute flight deals from Missouri to Puerto Rico. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Puerto Rico. Data last updated September 23, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:39 pm -
1 stop6h 13m
Mon 10/57:00 am -
1 stop10h 34m
Deal found 9/21![Frontier logo]()
$404
This FlightHub deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:39 pm -
1 stop14h 34m
Sun 10/411:08 am -
1 stop6h 26m
Deal found 9/22![Frontier logo]()
$407
This Cheapflightsfares deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:19 pm -
1 stop15h 16m
Wed 10/76:30 am -
1 stop7h 40m
Deal found 9/20![Frontier logo]()
$399
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:19 pm -
1 stop7h 33m
Sun 10/44:30 pm -
2 stops21h 40m
Deal found 9/22![Frontier logo]()
$486
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:32 pm -
2 stops37h 21m
Thu 10/157:00 am -
1 stop26h 26m
Deal found 9/19![Multiple Airlines logo]()
$444
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:32 pm -
2 stops37h 21m
Sun 10/117:00 am -
1 stop27h 16m
Deal found 9/19![Multiple Airlines logo]()
$455
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:04 pm -
1 stop11h 49m
Sun 10/187:20 am -
1 stop29h 19m
Deal found 9/23![Multiple Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:39 am -
1 stop7h 44m
Fri 10/233:51 pm -
1 stop7h 48m
Deal found 9/20![American Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
2 stops15h 57m
Mon 10/266:30 am -
2 stops17h 09m
Deal found 9/23![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:39 am -
1 stop15h 41m
Fri 10/303:51 pm -
1 stop7h 48m
Deal found 9/23![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop8h 23m
Mon 11/24:59 pm -
1 stop17h 26m
Deal found 9/22![American Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:08 pm -
2 stops17h 12m
Mon 11/24:59 pm -
1 stop17h 26m
Deal found 9/22![American Airlines logo]()
$391
One-way flights from Missouri to Puerto RicoSearch for one-way flight options from Missouri to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Missouri to Puerto Rico. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
1 stop20h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:44 pm -
2 stops19h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$101
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:35 pm -
2 stops20h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:35 pm -
2 stops30h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
2 stops30h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:35 pm -
2 stops20h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:35 pm -
2 stops30h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:44 pm -
2 stops41h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:35 pm -
2 stops29h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Frontier logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:16 am -
1 stop28h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:16 am -
1 stop29h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$150
This Frontier deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1410:30 am -
1 stop13h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Frontier logo]()
$174
Find flight deals from Missouri to Puerto Rico
Keep the following information in mind while searching for Missouri to Puerto Rico flight deals. Data was last updated September 23, 2026.
Round-trip from | $195 (Kiwi.com) |
|---|---|
One-way from | $92 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $336 |
Good round-trip deal | $572 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Puerto Rico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Missouri to Puerto Rico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan Juan
STL Lambert-St Louis - SJU San Juan Luis Munoz Marin Intl
STLSJU
Lambert-St Louis
Fri 10/16
6:35 pm-10:19 am
2 stops38h 44m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$130
St. LouisSan Juan
STL Lambert-St Louis - SJU San Juan Luis Munoz Marin Intl
STLSJU
Lambert-St Louis
Fri 12/11
12:02 pm-1:07 am
1 stop11h 05m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$147
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Sun 1/17
10:35 am-11:50 pm
1 stop11h 15m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Mon 11/2
8:01 am-9:38 pm
2 stops11h 37m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Sun 11/1
6:00 am-10:22 pm
2 stops14h 22m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Fri 11/13
3:50 pm-1:10 am
1 stop7h 20m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Wed 1/20
9:43 am-12:36 am
2 stops12h 53m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Wed 1/20
2:30 pm-11:50 pm
1 stop7h 20m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Sun 10/18
6:32 pm-9:46 am
2 stops14h 14m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Kansas CitySan Juan
MCI Kansas City - SJU San Juan Luis Munoz Marin Intl
MCISJU
Kansas City
Thu 10/22
2:35 pm-11:10 pm
1 stop7h 35m
San Juan Luis Munoz Marin Intl
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$193
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Puerto Rico
Have a flexible travel schedule? Discover the best time to fly to Puerto Rico from Missouri with our price prediction graph.
STL-SJU
MCI-SJU
SGF-SJU
COU-SJU
MCI-BQN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Puerto Rico
USMO-PR0
STL-SJU
MCI-SJU
SGF-SJU
COU-SJU
What is the cheapest month to book a flight from Missouri to Puerto Rico?
Currently, September is the cheapest month in which you can book a flight from Missouri to Puerto Rico (average of $347). Flying from Missouri to Puerto Rico in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Missouri to Puerto Rico?
The price you pay for your flight from Missouri to Puerto Rico may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Puerto Rico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Puerto Rico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Puerto Rico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Puerto Rico by cabin class
Find flights from Missouri to Puerto Rico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Puerto Rico flights
Browse other Missouri and Puerto Rico flight options. Last updated on September 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Puerto Rico flights
Consider these flights traveling from Missouri to Puerto Rico.
Top 6 airlines flying from Missouri to Puerto Rico
Discover the top 6 airlines that operate flights from Missouri to Puerto Rico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$460 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$132 | Average$351 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$215 | Average$444 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$235 | Average$540 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$326 | Average$506 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$381 | Average$572 | FlexibilityNo cancel fee | On-time62% |