Prague

$535+ Cheap flights from Knoxville (TYS) to Prague (PRG)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PRG
Oct 11 — Oct 181
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Prague with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Prague

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Prague (PRG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$557
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$1,058
From Knoxville McGhee Tyson to Václav Havel Prague
Highest demand for flights based on searches. 21% potential increase in price ($261 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($45 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Knoxville to Prague

Cheapest flights from Knoxville to Prague
Explore the most affordable flight options available from Knoxville to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/272:25 pmTYS - PRG
2 stops18h 30mUnited Airlines
Wed 11/127:30 amPRG - TYS
2 stops22h 29mUnited Airlines
Deal found 9/9$535
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:45 amTYS - PRG
2 stops26h 20mUnited Airlines
Fri 11/1412:10 pmPRG - TYS
2 stops27h 55mUnited Airlines
Deal found 9/9$538
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:45 amTYS - PRG
2 stops24h 05mUnited Airlines
Wed 11/1212:10 pmPRG - TYS
2 stops17h 49mUnited Airlines
Deal found 9/9$543
This Scandinavian Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:16 pmTYS - PRG
2 stops16h 04mScandinavian Airlines
Mon 11/1710:25 amPRG - TYS
2 stops19h 27mScandinavian Airlines
Deal found 9/9$546
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/272:25 pmTYS - PRG
2 stops18h 30mUnited Airlines
Mon 11/173:10 pmPRG - TYS
2 stops31h 58mUnited Airlines
Deal found 9/9$555
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/45:52 pmTYS - PRG
2 stops16h 13mUnited Airlines
Mon 11/103:10 pmPRG - TYS
2 stops35h 10mUnited Airlines
Deal found 9/10$557
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/272:25 pmTYS - PRG
2 stops18h 30mUnited Airlines
Sat 11/157:35 amPRG - TYS
2 stops18h 45mUnited Airlines
Deal found 9/9$585
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:20 pmTYS - PRG
2 stops22h 05mUnited Airlines
Tue 11/1111:50 amPRG - TYS
2 stops18h 09mUnited Airlines
Deal found 9/9$588
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:45 amTYS - PRG
2 stops24h 05mUnited Airlines
Sat 11/156:50 amPRG - TYS
2 stops19h 30mUnited Airlines
Deal found 9/9$608
This KAYAK deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:20 pmTYS - PRG
2 stops22h 05mLufthansa
Mon 11/176:55 pmPRG - TYS
2 stops31h 25mLufthansa
Deal found 9/9$612
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:26 pmTYS - PRG
2 stops39h 39mUnited Airlines
Sat 11/17:35 amPRG - TYS
2 stops42h 58mUnited Airlines
Deal found 9/10$613
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:23 pmTYS - PRG
2 stops40h 32mUnited Airlines
Mon 12/293:10 pmPRG - TYS
2 stops38h 49mUnited Airlines
Deal found 9/9$623

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Knoxville to Prague that are best for you.

Fly from

Knoxville

Fly to

Prague

Route

Depart

Return

Price

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Mon 10/27

2:25 pm-1:55 pm

2 stops18h 30m

Václav Havel Prague

Thu 11/13

7:35 am-11:59 pm

2 stops22h 24m

$535

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Mon 10/27

2:25 pm-1:55 pm

2 stops18h 30m

Václav Havel Prague

Tue 11/11

11:50 am-11:59 pm

2 stops18h 09m

$535

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Mon 10/27

2:25 pm-1:55 pm

2 stops18h 30m

Václav Havel Prague

Wed 11/12

7:30 am-11:59 pm

2 stops22h 29m

$535

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Mon 10/27

2:25 pm-1:55 pm

2 stops18h 30m

Václav Havel Prague

Fri 11/14

12:10 pm-10:05 am

2 stops27h 55m

$535

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Wed 10/29

5:45 am-1:05 pm

2 stops26h 20m

Václav Havel Prague

Fri 11/14

12:10 pm-10:05 am

2 stops27h 55m

$538

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Tue 10/28

5:45 am-10:50 am

2 stops24h 05m

Václav Havel Prague

Wed 11/12

12:10 pm-11:59 pm

2 stops17h 49m

$543

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Tue 10/28

5:45 am-10:50 am

2 stops24h 05m

Václav Havel Prague

Fri 11/14

12:10 pm-11:59 pm

2 stops17h 49m

$543

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Tue 10/28

5:45 am-10:50 am

2 stops24h 05m

Václav Havel Prague

Thu 11/13

11:50 am-11:59 pm

2 stops18h 09m

$543

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Tue 10/28

5:16 pm-2:20 pm

2 stops16h 04m

Václav Havel Prague

Mon 11/17

10:25 am-11:52 pm

2 stops19h 27m

$546

KnoxvillePrague

TYS - PRG

TYSPRG

Knoxville McGhee Tyson

Wed 10/29

3:48 pm-2:20 pm

2 stops17h 32m

Václav Havel Prague

Mon 11/17

10:25 am-11:52 pm

2 stops19h 27m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 12 results
1
2

Best time to book a flight from Knoxville to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Prague

What is the cheapest month to book a flight from Knoxville to Prague?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Prague (average of $651). Flying from Knoxville to Prague in June is currently the most expensive (average of $1,119). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to PRG?

Find hourly flight availability from Knoxville to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s typically best to fly out from Knoxville to Prague in the morning. Doing so could potentially save you 12% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Prague

Get insights into the airlines that provide service to Prague. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Prague. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Knoxville to Prague, such as Delta, KLM, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Knoxville to Prague?

    Departing from Knoxville to Prague will take you 18h 30m. The distance from Knoxville to Prague is about 4697 mi.

  • What are the cheapest airlines flying from Knoxville to Prague round-trip?

    Flying on American Airlines is currently your cheapest option to Prague, with prices starting at $626. Additional round-trip tickets that might be worth considering are offered by Lufthansa and Delta, with the lowest prices starting at $648 and $708, respectively. American Airlines is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Prague that include hotel bookings?

    Yes. In addition to deals on Knoxville to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Prague.

  • Can I find deals for business class flights from Knoxville to Prague?

    Yes. Cheapflights offers flight deals from Knoxville to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Prague?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Prague (average of $651). Flying from Knoxville to Prague in June is currently the most expensive (average of $1,119). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Prague

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Knoxville to Prague

Discover the top 5 airlines that operate flights from Knoxville to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$626Average$750FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$648Average$980FlexibilityNo cancel feeOn-time76%
DeltaCheapest$708Average$1,124FlexibilityNo cancel feeOn-timeN/A
KLMCheapest$714Average$969FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$717Average$969FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.