Prague

$405+ Cheap flights from Iowa to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PRG
Jan 14 — Jan 211
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Cheap flight deals from Iowa to Prague

Cheapest flights from Iowa to Prague
Explore the most affordable flight options available from Iowa to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:06 pmDSM - PRG
2 stops37h 59mUnited Airlines
Thu 1/157:35 amPRG - DSM
2 stops21h 15mUnited Airlines
Deal found 12/13$727
This Orbitz deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:46 pmDSM - PRG
2 stops55h 59mLufthansa
Thu 1/157:35 amPRG - DSM
2 stops21h 15mLufthansa
Deal found 12/14$819
This FlightHub deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:08 pmOMA - PRG
2 stops35h 37mScandinavian Airlines
Sun 12/2110:25 amPRG - OMA
2 stops20h 43mScandinavian Airlines
Deal found 12/13$1,216
This Gurufare deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:28 pmCID - PRG
2 stops15h 37mLufthansa
Sat 1/107:35 amPRG - CID
2 stops20h 59mLufthansa
Deal found 12/14$1,691
This Booking.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:10 amCID - PRG
2 stops20h 30mMultiple Airlines
Sat 1/106:50 amPRG - CID
3 stops21h 44mMultiple Airlines
Deal found 12/14$1,785
This Air Canada deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:35 amDSM - PRG
3 stops19h 20mAir Canada
Thu 1/157:35 amPRG - DSM
3 stops21h 15mAir Canada
Deal found 12/13$2,006
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/146:35 pmOMA - PRG
2 stops44h 50mUnited Airlines
Sun 1/43:00 pmPRG - OMA
2 stops36h 19mUnited Airlines
Deal found 12/14$2,203
This Ovago deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:20 pmOMA - PRG
2 stops35h 45mLufthansa
Sun 1/43:00 pmPRG - OMA
2 stops36h 19mLufthansa
Deal found 12/14$2,464
This oojo deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:12 amOMA - PRG
2 stops19h 28mBritish Airways
Sat 12/207:15 pmPRG - OMA
2 stops30h 24mBritish Airways
Deal found 12/14$2,569
This Air Canada deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:28 amOMA - PRG
3 stops18h 37mAir Canada
Sun 12/217:25 amPRG - OMA
3 stops21h 33mAir Canada
Deal found 12/13$2,623
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:00 amOMA - PRG
3 stops25h 05mUnited Airlines
Sat 12/207:35 amPRG - OMA
2 stops19h 44mUnited Airlines
Deal found 12/14$2,915
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:19 pmOMA - PRG
2 stops18h 26mDelta
Sun 1/46:00 amPRG - OMA
2 stops20h 46mDelta
Deal found 12/13$2,978

Find flight deals from Iowa to Prague

Keep the following information in mind while searching for Iowa to Prague flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$462
(Ticket)

One-way from

$405
(Gotogate)
Provider with most accurate pricing for Des Moines-Václav Havel Prague flight deals.
Provider most trusted by Cheapflights users for Des Moines-Václav Havel Prague flights.
From Iowa to Václav Havel Prague
One-way flight from Iowa to Václav Havel Prague

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Iowa to Prague that are best for you.

Fly from

Iowa

Fly to

Prague

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 1/29

6:48 pm-4:05 pm

2 stops14h 17m

Václav Havel Prague

Thu 2/5

7:35 am-9:50 pm

2 stops21h 15m

$462

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 1/27

6:48 pm-4:05 pm

2 stops14h 17m

Václav Havel Prague

Tue 2/3

7:25 am-9:50 pm

2 stops21h 25m

$469

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 1/23

11:30 am-1:05 pm

2 stops18h 35m

Václav Havel Prague

Fri 1/30

7:35 am-9:50 pm

2 stops21h 15m

$479

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 1/29

3:35 pm-1:05 pm

2 stops14h 30m

Václav Havel Prague

Thu 2/5

7:35 am-8:34 pm

2 stops19h 59m

$481

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 1/27

11:26 am-11:40 am

2 stops17h 14m

Václav Havel Prague

Tue 2/3

6:00 am-4:28 pm

2 stops17h 28m

$489

OmahaPrague

OMA - PRG

OMAPRG

Omaha Eppley Airfield

Thu 2/19

6:45 pm-4:05 pm

2 stops14h 20m

Václav Havel Prague

Thu 2/26

7:35 am-9:59 pm

2 stops21h 24m

$493

OmahaPrague

OMA - PRG

OMAPRG

Omaha Eppley Airfield

Thu 2/5

6:35 pm-4:05 pm

2 stops14h 30m

Václav Havel Prague

Wed 2/18

10:15 am-8:12 pm

2 stops16h 57m

$494

OmahaPrague

OMA - PRG

OMAPRG

Omaha Eppley Airfield

Tue 1/27

5:40 pm-5:30 pm

2 stops16h 50m

Václav Havel Prague

Tue 2/3

6:45 am-5:41 pm

2 stops17h 56m

$495

OmahaPrague

OMA - PRG

OMAPRG

Omaha Eppley Airfield

Sun 1/18

5:40 pm-8:45 pm

2 stops20h 05m

Václav Havel Prague

Sun 1/25

8:40 pm-5:49 pm

2 stops28h 09m

$495

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 1/28

5:01 pm-10:50 pm

2 stops22h 49m

Václav Havel Prague

Wed 2/4

6:50 am-9:04 pm

2 stops21h 14m

$495

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 29 results
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Best time to book a flight from Iowa to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Prague
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Prague from Iowa?

    Located just 6.9 mi from the city center, Václav Havel Prague (PRG) is the airport most travelers will use when flying to Prague from Iowa.

  • How long is the flight from Iowa to Prague?

    A quick flight from Iowa to Prague can take about 14h 17m. Lufthansa provides one of the quickest options available for as low as $462. There are 4753 mi between Iowa and Prague. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Prague?

  • Can I find deals for flights from Iowa to Prague that include hotel bookings?

    Yes. In addition to deals on Iowa to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Prague.

  • Can I find deals for business class flights from Iowa to Prague?

    Yes. Cheapflights offers flight deals from Iowa to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Prague

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Iowa to Prague

Discover the top airline that operate flights from Iowa to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$597Average$939FlexibilityNo cancel feeOn-time69%

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