$451+ Cheap flights from La Crosse to Portland, ME (LSE - PWM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — PWM
Nov 26 — Dec 31
1 adult, Economy
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Cheapest flights from La Crosse to PortlandExplore the most affordable flight options available from La Crosse to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.
Explore the most affordable flight options available from La Crosse to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:50 amLSE - PWM
1 stop6h 15mAmerican Airlines
Tue 11/256:00 amPWM - LSE
2 stops12h 43mAmerican Airlines
Deal found 10/25![American Airlines logo]()
$660
Cheap flight deals from La Crosse to Portland
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 1 star |
Round-trip from | $451 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from La Crosse to Portland that are best for you.
Fly from
La Crosse
Fly to
Portland
Route
Depart
Return
Price
La CrossePortland
LSE - PWM
LSEPWM
La Crosse
Fri 1/9
11:37 am-10:07 pm
2 stops9h 30m
Portland
Tue 1/20
3:56 pm-10:17 pm
2 stops7h 21m
$451
La CrossePortland
LSE - PWM
LSEPWM
La Crosse
Tue 2/10
6:00 am-3:31 pm
2 stops8h 31m
Portland
Sat 2/21
5:47 am-2:18 pm
2 stops9h 31m
$485
La CrossePortland
LSE - PWM
LSEPWM
La Crosse
Sat 3/7
10:03 am-10:49 pm
2 stops11h 46m
Portland
Wed 3/11
5:52 am-2:18 pm
2 stops9h 26m
$590
La CrossePortland
LSE - PWM
LSEPWM
La Crosse
Fri 3/6
6:26 pm-11:39 am
2 stops16h 13m
Portland
Tue 3/17
12:26 pm-9:40 pm
2 stops10h 14m
$618
La CrossePortland
LSE - PWM
LSEPWM
La Crosse
Fri 11/14
9:50 am-5:05 pm
1 stop6h 15m
Portland
Tue 11/25
6:00 am-5:43 pm
2 stops12h 43m
$660
- Most accurate provider: When it comes to deals on La Crosse-Portland, Maine flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Portland, Maine flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Portland, Maine flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-Portland, Maine flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Portland, Maine flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to Portland
Have a flexible travel schedule? Discover the best time to fly to Portland from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Portland?
Book flights to Portland if you plan to visit one of these locationsNorth Conway
Brunswick
Auburn
Conway