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$404+ Cheap flights from Tuscany to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
FLR — PTY
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Tuscany to Panama

Keep the following information in mind while searching for Tuscany to Panama flight deals. Data was last updated October 16, 2025.

Round-trip from

$634
(FlightHub)

One-way from

$404
(Turkish Airlines)
From Tuscany to Panama
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One-way flight from Tuscany to Panama
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Find flight deals from Tuscany to Panama

Cheapest flights from Tuscany to Panama
Explore the most affordable flight options available from Tuscany to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Booking.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/307:35 pmFCO - PTY
1 stop30h 15mTurkish Airlines
Sun 12/76:45 pmPTY - FCO
1 stop33h 05mTurkish Airlines
Deal found 10/16$667
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:25 pmFCO - PTY
2 stops29h 31mDelta
Tue 12/233:22 pmPTY - FCO
1 stop37h 08mDelta
Deal found 10/16$774
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:25 pmFCO - PTY
2 stops29h 31mDelta
Wed 12/248:00 amPTY - FCO
1 stop20h 30mDelta
Deal found 10/16$779
This Gotogate deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2910:30 amFCO - PTY
1 stop15h 15mAir Europa
Sat 12/69:30 pmPTY - FCO
1 stop13h 55mAir Europa
Deal found 10/15$800
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:05 amFCO - PTY
1 stop34h 07mDelta
Sun 11/233:37 pmPTY - FCO
2 stops33h 28mDelta
Deal found 10/16$803
This Air Europa deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:25 pmFCO - PTY
1 stop31h 20mAir Europa
Sun 12/149:30 pmPTY - FCO
1 stop13h 55mAir Europa
Deal found 10/15$822
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amFCO - PTY
2 stops19h 45mMultiple Airlines
Sat 12/69:30 pmPTY - FCO
2 stops18h 10mMultiple Airlines
Deal found 10/15$858

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tuscany to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Tuscany to Panama that are best for you.

Fly from

Tuscany

Fly to

Panama

Route

Depart

Return

Price

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sun 3/8

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Sun 5/24

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 3/7

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Mon 5/18

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 3/5

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Tue 5/19

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 3/10

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Sun 5/24

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 3/5

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Thu 5/21

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Wed 3/11

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Thu 5/21

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 3/7

10:30 am-7:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Tue 5/19

8:25 pm-5:25 pm

1 stop14h 00m

$662

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Mon 12/8

6:45 am-7:50 pm

1 stop19h 05m

Panama City Tocumen Intl

Fri 3/6

6:45 pm-9:55 pm

1 stop21h 10m

$667

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 3/10

7:45 pm-5:05 pm

2 stops27h 20m

Panama City Tocumen Intl

Mon 5/18

10:15 pm-11:35 pm

1 stop18h 20m

$701

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Fri 3/6

7:45 pm-5:05 pm

2 stops27h 20m

Panama City Tocumen Intl

Wed 5/20

10:15 pm-11:35 pm

1 stop18h 20m

$701

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 17 results
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Best time to book a flight from Tuscany to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Tuscany with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tuscany to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Tuscany to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tuscany to Panama?

    Departing from Tuscany to Panama will take you 15h 15m. Airlines will cover a distance of 5881 mi.

  • Can I find deals for flights from Tuscany to Panama that include hotel bookings?

    Yes. In addition to deals on Tuscany to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tuscany to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tuscany to Panama.

  • Can I find deals for business class flights from Tuscany to Panama?

    Yes. Cheapflights offers flight deals from Tuscany to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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