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$372+ Cheap flights from Tuscany to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
FLR — PTY
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Tuscany to Panama

Keep the following information in mind while searching for Tuscany to Panama flight deals. Data was last updated August 20, 2025.

Round-trip from

$768
(KLM)

One-way from

$372
(Vueling Global)
From Tuscany to Panama
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One-way flight from Tuscany to Panama
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Find flight deals from Tuscany to Panama

Cheapest flights from Tuscany to Panama
Explore the most affordable flight options available from Tuscany to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Condor deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Condor is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/278:20 amFCO - PTY
1 stop25h 20mMultiple Airlines
Fri 9/1210:25 amPTY - FCO
2 stops23h 30mMultiple Airlines
Deal found 8/20$689
This KLM deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1112:45 pmFCO - PTY
1 stop35h 05mMultiple Airlines
Tue 9/167:55 pmPTY - FCO
1 stop20h 15mMultiple Airlines
Deal found 8/18$768
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/410:10 amFCO - PTY
2 stops33h 40mDelta
Mon 9/82:05 pmPTY - FCO
1 stop34h 30mDelta
Deal found 8/19$779
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/119:00 amFCO - PTY
2 stops34h 55mDelta
Tue 9/162:10 pmPTY - FCO
2 stops21h 55mDelta
Deal found 8/20$797
This KLM deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:40 pmFCO - PTY
1 stop28h 10mMultiple Airlines
Wed 9/102:05 pmPTY - FCO
1 stop34h 30mMultiple Airlines
Deal found 8/20$828
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:10 amFCO - PTY
2 stops37h 42mDelta
Sat 11/158:05 amPTY - FCO
2 stops18h 35mDelta
Deal found 8/18$849
This Orbitz deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:30 amFCO - PTY
1 stop15h 15mIberia
Sat 11/156:20 pmPTY - FCO
1 stop23h 55mIberia
Deal found 8/18$857
This Air France deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:05 amFCO - PTY
1 stop18h 40mMultiple Airlines
Wed 10/226:50 pmPTY - FCO
1 stop33h 55mMultiple Airlines
Deal found 8/18$875

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tuscany to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Tuscany to Panama that are best for you.

Fly from

Tuscany

Fly to

Panama

Route

Depart

Return

Price

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 9/11

12:45 pm-4:50 pm

1 stop35h 05m

Panama City Tocumen Intl

Tue 9/16

7:55 pm-11:10 pm

1 stop20h 15m

$768

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 9/4

11:35 am-12:50 pm

1 stop32h 15m

Panama City Tocumen Intl

Mon 9/8

2:05 pm-7:35 am

1 stop34h 30m

$779

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 9/11

9:00 am-12:55 pm

2 stops34h 55m

Panama City Tocumen Intl

Tue 9/16

2:10 pm-7:05 pm

2 stops21h 55m

$797

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 2/7

6:10 am-8:04 pm

2 stops19h 54m

Panama City Tocumen Intl

Sun 3/1

3:27 pm-4:25 pm

2 stops18h 58m

$833

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 11/8

6:10 am-1:52 pm

2 stops37h 42m

Panama City Tocumen Intl

Sat 11/15

8:05 am-8:40 am

2 stops18h 35m

$849

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 11/8

7:30 am-4:45 pm

1 stop15h 15m

Panama City Tocumen Intl

Sat 11/15

6:20 pm-12:15 am

1 stop23h 55m

$857

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Tue 2/10

10:30 pm-12:40 am

2 stops32h 10m

$372

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Fri 9/26

3:30 pm-6:20 pm

2 stops33h 50m

$407

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 9/20

7:00 am-6:20 pm

2 stops42h 20m

$407

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sun 2/8

11:15 am-7:50 pm

1 stop38h 35m

$433

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 13 results
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Best time to book a flight from Tuscany to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Tuscany with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tuscany to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Tuscany to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tuscany to Panama?

    Departing from Tuscany to Panama will take you 32h 15m. Airlines will cover a distance of 5881 mi.

  • Can I find deals for flights from Tuscany to Panama that include hotel bookings?

    Yes. In addition to deals on Tuscany to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tuscany to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tuscany to Panama.

  • Can I find deals for business class flights from Tuscany to Panama?

    Yes. Cheapflights offers flight deals from Tuscany to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tuscany to Panama?

    Currently, October is the cheapest month in which you can book a flight from Tuscany to Panama (average of $478). Flying from Tuscany to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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