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$397+ Cheap flights from Tuscany to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
FLR — PTY
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from Tuscany to Panama

Cheapest flights from Tuscany to Panama
Explore the most affordable flight options available from Tuscany to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Booking.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:45 pm
FCO
-
PTY
2 stops27h 20m
Turkish Airlines
Sat 3/146:45 pm
PTY
-
FCO
1 stop21h 10m
Turkish Airlines
Deal found 1/20$648
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:45 pm
FCO
-
PTY
2 stops27h 20m
Turkish Airlines
Sat 3/79:45 pm
PTY
-
FCO
1 stop18h 10m
Turkish Airlines
Deal found 1/21$649
This Booking.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/167:35 pm
FCO
-
PTY
2 stops27h 30m
Turkish Airlines
Mon 2/239:45 pm
PTY
-
FCO
1 stop30h 05m
Turkish Airlines
Deal found 1/21$650
This Turkish Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:45 am
FCO
-
PTY
2 stops40h 20m
Turkish Airlines
Thu 3/196:45 pm
PTY
-
FCO
1 stop37h 05m
Turkish Airlines
Deal found 1/20$661
This Air Europa deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:55 pm
FCO
-
PTY
1 stop33h 50m
Air Europa
Mon 11/169:30 pm
PTY
-
FCO
1 stop13h 55m
Air Europa
Deal found 1/20$681
This Air Europa deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:30 am
FCO
-
PTY
1 stop15h 10m
Air Europa
Mon 5/258:25 pm
PTY
-
FCO
1 stop14h 00m
Air Europa
Deal found 1/19$750
This Air Europa deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:25 pm
FCO
-
PTY
1 stop31h 15m
Air Europa
Sat 5/28:25 pm
PTY
-
FCO
1 stop30h 05m
Air Europa
Deal found 1/20$759

Find flight deals from Tuscany to Panama

Keep the following information in mind while searching for Tuscany to Panama flight deals. Data was last updated January 21, 2026.

Round-trip from

$648
(Booking.com)

One-way from

$397
(Kiwi.com)
From Tuscany to Panama
Search Deals
One-way flight from Tuscany to Panama
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tuscany to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Tuscany to Panama that are best for you.

Fly from

Tuscany

Fly to

Panama

Route

Depart

Return

Price

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Fri 2/20

7:45 pm-5:05 pm

2 stops27h 20m

Panama City Tocumen Intl

Sat 3/14

6:45 pm-9:55 pm

1 stop21h 10m

$648

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Fri 2/27

7:45 pm-5:05 pm

2 stops27h 20m

Panama City Tocumen Intl

Sat 3/7

9:45 pm-9:55 pm

1 stop18h 10m

$649

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Fri 3/6

10:50 am-5:05 pm

2 stops36h 15m

Panama City Tocumen Intl

Thu 3/19

6:45 pm-6:20 pm

1 stop17h 35m

$665

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Fri 5/22

10:30 am-6:40 pm

1 stop15h 10m

Panama City Tocumen Intl

Mon 5/25

8:25 pm-5:25 pm

1 stop14h 00m

$750

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 4/18

10:30 am-6:40 pm

1 stop15h 10m

Panama City Tocumen Intl

Sat 5/2

8:25 pm-9:30 am

1 stop30h 05m

$788

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 4/9

6:25 pm-6:40 pm

1 stop31h 15m

Panama City Tocumen Intl

Sun 4/19

8:25 pm-5:25 pm

1 stop14h 00m

$819

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Sat 1/31

6:45 am-7:50 pm

1 stop19h 05m

$397

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Mon 1/26

6:45 am-7:50 pm

1 stop19h 05m

$397

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Mon 5/4

9:55 pm-12:10 am

2 stops33h 15m

$398

RomePanama City

FCO - PTY

FCOPTY

Rome Fiumicino

Thu 1/29

7:35 pm-5:05 pm

2 stops27h 30m

$404

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 14 results
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Best time to book a flight from Tuscany to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Tuscany with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tuscany to Panama
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Tuscany to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tuscany to Panama?

    Departing from Tuscany to Panama will take you 27h 20m. Airlines will cover a distance of 5881 mi.

  • Can I find deals for flights from Tuscany to Panama that include hotel bookings?

    Yes. In addition to deals on Tuscany to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tuscany to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tuscany to Panama.

  • Can I find deals for business class flights from Tuscany to Panama?

    Yes. Cheapflights offers flight deals from Tuscany to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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