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$105+ Cheap flights from Tampa (TPA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — PTY
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Tampa to Panama

Keep the following information in mind while searching for Tampa to Panama flight deals. Data was last updated September 16, 2025.

Round-trip from

$270
(Cheapflightsfares)

One-way from

$105
(Trip.com)

Popular in

December

Cheapest in

September

Average price

$406

Good round-trip deal

$312 or less

Good one-way deal

$141 or less
From Tampa to Panama
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One-way flight from Tampa to Panama
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Highest demand for flights based on searches. 13% potential increase in price ($70 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Tampa to Panama.
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Price to beat on a one-way flight from Tampa to Panama.
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Find flight deals from Tampa to Panama

Cheapest flights from Tampa to Panama
Explore the most affordable flight options available from Tampa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/172:15 pmTPA - PTY
1 stop7h 55mAvianca
Wed 10/295:55 pmPTY - TPA
1 stop19h 30mAvianca
Deal found 9/16$270
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:57 pmTPA - PTY
Nonstop3h 21mCopa Airlines
Wed 10/299:11 amPTY - TPA
Nonstop3h 23mCopa Airlines
Deal found 9/14$272
This Avianca deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:55 pmTPA - PTY
1 stop9h 45mAvianca
Tue 12/92:55 amPTY - TPA
1 stop34h 30mAvianca
Deal found 9/16$273
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/152:15 pmTPA - PTY
1 stop11h 30mAvianca
Tue 10/282:55 amPTY - TPA
1 stop10h 30mAvianca
Deal found 9/14$274
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/293:55 pmTPA - PTY
1 stop9h 45mAvianca
Tue 11/42:55 amPTY - TPA
1 stop34h 30mAvianca
Deal found 9/14$277
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:52 amTPA - PTY
1 stop6h 11mAmerican Airlines
Wed 10/223:15 pmPTY - TPA
1 stop7h 44mAmerican Airlines
Deal found 9/15$286
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:39 pmTPA - PTY
2 stops22h 24mAmerican Airlines
Fri 10/173:15 pmPTY - TPA
1 stop7h 44mAmerican Airlines
Deal found 9/16$291
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:40 pmTPA - PTY
1 stop19h 23mAmerican Airlines
Tue 10/213:15 pmPTY - TPA
1 stop15h 47mAmerican Airlines
Deal found 9/16$292
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:23 pmTPA - PTY
1 stop26h 14mUnited Airlines
Mon 10/133:30 pmPTY - TPA
1 stop18h 07mUnited Airlines
Deal found 9/16$293
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1610:11 amTPA - PTY
1 stop4h 52mAmerican Airlines
Thu 10/233:15 pmPTY - TPA
2 stops18h 48mAmerican Airlines
Deal found 9/16$295
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:11 pmTPA - PTY
2 stops21h 52mAmerican Airlines
Fri 10/243:15 pmPTY - TPA
1 stop15h 47mAmerican Airlines
Deal found 9/14$301
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/125:57 pmTPA - DAV
1 stop14h 41mCopa Airlines
Sun 10/198:18 amDAV - TPA
1 stop6h 54mCopa Airlines
Deal found 9/14$737

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Tampa to Panama that are best for you.

Fly from

Tampa

Fly to

Panama

Route

Depart

Return

Price

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Wed 10/15

3:15 pm-5:40 pm

Nonstop3h 25m

Panama City Tocumen Intl

Wed 10/29

9:11 am-1:34 pm

Nonstop3h 23m

$272

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Tue 9/30

3:16 pm-5:40 pm

Nonstop3h 24m

Panama City Tocumen Intl

Tue 10/14

9:06 am-1:29 pm

Nonstop3h 23m

$272

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Wed 10/15

2:15 pm-9:10 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 10/21

3:20 am-12:15 pm

1 stop7h 55m

$274

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Wed 10/15

2:15 pm-8:55 am

1 stop19h 40m

Panama City Tocumen Intl

Wed 10/29

5:55 pm-2:25 pm

1 stop19h 30m

$274

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Mon 10/6

5:23 pm-6:37 pm

1 stop26h 14m

Panama City Tocumen Intl

Mon 10/13

3:30 pm-10:37 am

1 stop18h 07m

$293

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Wed 10/8

5:57 pm-8:18 pm

Nonstop3h 21m

Panama City Tocumen Intl

Thu 10/16

9:06 am-1:29 pm

Nonstop3h 23m

$317

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Wed 10/8

3:15 pm-5:40 pm

Nonstop3h 25m

Panama City Tocumen Intl

Wed 10/15

9:06 am-1:29 pm

Nonstop3h 23m

$317

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Fri 11/14

4:52 pm-1:49 pm

2 stops20h 57m

Panama City Tocumen Intl

Wed 11/19

2:49 pm-11:12 am

2 stops20h 23m

$362

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Thu 10/23

3:15 pm-5:40 pm

Nonstop3h 25m

Panama City Tocumen Intl

Mon 10/27

9:11 am-1:34 pm

Nonstop3h 23m

$394

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Thu 10/30

5:57 pm-8:22 pm

Nonstop3h 25m

Panama City Tocumen Intl

Mon 11/3

9:11 am-12:34 pm

Nonstop3h 23m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 29 results
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Best time to book a flight from Tampa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Panama

What is the cheapest month to book a flight from Tampa to Panama?

Currently, October is the cheapest month in which you can book a flight from Tampa to Panama (average of $478). Flying from Tampa to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to PA?

Find hourly flight availability from Tampa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

One of the essential ways to save on airfare from Tampa to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 20% on airfare.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 16, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Tampa to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Avianca
6.7
Okay
2,435 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Tampa to Panama?

    Located just 4.9 mi from the city center, Tampa (TPA) is the airport most travelers will use when flying to Panama from Tampa.

  • How popular is this Tampa to Panama flight route?

    The Tampa to Panama flight path was viewed by 127 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Tampa to Panama?

    A quick flight from Tampa to Panama can take about 3h 25m. Copa Airlines provides one of the quickest options available for as low as $272. The distance between Tampa and Panama is about 1321 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Tampa to Panama?

    On average you can expect to pay $522 for a flight from Tampa to Panama. The cheapest flight overall is $110 while the most popular route, (Tampa - Panama City Tocumen Intl) is currently priced at $272.

  • Can I find deals for flights from Tampa to Panama that include hotel bookings?

    Yes. In addition to deals on Tampa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Panama.

  • Can I find deals for business class flights from Tampa to Panama?

    Yes. Cheapflights offers flight deals from Tampa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Panama?

    Currently, October is the cheapest month in which you can book a flight from Tampa to Panama (average of $478). Flying from Tampa to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Tampa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Panama City flights
Miami to Managua flights
Orlando to Panama City flights
Miami to San Salvador flights
Miami to San José flights
Orlando to San José flights
Fort Lauderdale to San José flights
Tampa to Panama City flights
Miami to Guatemala City flights
Fort Lauderdale to Guatemala City flights
Tampa to San José flights
Orlando to Guatemala City flights
Fort Lauderdale to Panama City flights
Miami to Liberia flights
Miami to Philip S.W.Goldson flights
Orlando to San Salvador flights
Tampa to Liberia flights
Miami to San Pedro Sula flights
Tampa to Philip S.W.Goldson flights
Orlando to Liberia flights
Fort Lauderdale to San Pedro Sula flights
Orlando to San Pedro Sula flights
Jacksonville to Panama City flights
Jacksonville to San José flights
Fort Lauderdale to Liberia flights
West Palm Beach to San José flights
Orlando to Managua flights
Fort Lauderdale to Managua flights
Orlando to Philip S.W.Goldson flights
Tampa to Guatemala City flights
Fort Lauderdale to San Salvador flights
Fort Myers to Philip S.W.Goldson flights
Tampa to San Salvador flights
Jacksonville to Philip S.W.Goldson flights
Jacksonville to Liberia flights
West Palm Beach to Panama City flights
Miami to Coxen Hole flights
Jacksonville to Guatemala City flights
Tampa to Managua flights
Fort Myers to Guatemala City flights
Fort Lauderdale to Philip S.W.Goldson flights
Pensacola to Panama City flights
Sarasota to San José flights
Panama City to San José flights
Tampa to Coxen Hole flights
West Palm Beach to Managua flights
West Palm Beach to San Salvador flights
Pensacola to San José flights
Tampa to San Pedro Sula flights

Top 5 airlines flying from Tampa to Panama

Discover the top 5 airlines that operate flights from Tampa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$213Average$379FlexibilityNo cancel feeOn-time71%
DeltaCheapest$293Average$488FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$331Average$509FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$372Average$452FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$397Average$643FlexibilityNo cancel feeOn-time69%

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