$286+ Cheap flights from Tampa (TPA) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — PTY
Oct 24 — Oct 311
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Tampa to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tampa to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from Tampa to PanamaExplore the most affordable flight options available from Tampa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
Explore the most affordable flight options available from Tampa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:51 am -
Nonstop3h 27m
Tue 12/16:42 pm -
Nonstop3h 18m
Deal found 9/22![Copa Airlines logo]()
$630
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:10 am -
1 stop8h 53m
Sun 12/133:29 pm -
1 stop8h 56m
Deal found 9/20![Delta logo]()
$637
This Copa Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:30 pm -
Nonstop3h 25m
Tue 12/19:16 am -
Nonstop3h 21m
Deal found 9/21![Copa Airlines logo]()
$640
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:22 pm -
2 stops20h 51m
Sat 12/123:13 pm -
1 stop8h 59m
Deal found 9/19![American Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:00 am -
1 stop9h 34m
Sun 12/63:13 pm -
1 stop8h 59m
Deal found 9/19![American Airlines logo]()
$642
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:47 pm -
2 stops19h 26m
Sun 12/133:13 pm -
1 stop8h 59m
Deal found 9/19![American Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop8h 13m
Sun 12/63:13 pm -
1 stop7h 58m
Deal found 9/19![American Airlines logo]()
$647
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:12 pm -
1 stop26h 26m
Wed 11/254:41 pm -
1 stop17h 53m
Deal found 9/20![United Airlines logo]()
$648
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop8h 13m
Sun 11/223:34 pm -
2 stops23h 10m
Deal found 9/19![American Airlines logo]()
$651
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:21 am -
1 stop12h 04m
Sat 10/247:57 pm -
1 stop19h 29m
Deal found 9/22![Copa Airlines logo]()
$1,037
This oojo deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:21 am -
1 stop14h 56m
Sat 10/248:26 am -
2 stops26h 59m
Deal found 9/19![Multiple Airlines logo]()
$1,081
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:18 pm -
2 stops40h 52m
Sat 10/249:50 am -
2 stops23h 44m
Deal found 9/19![United Airlines logo]()
$1,236
Best flights from Tampa to PanamaDiscover carefully curated flight deals from Tampa to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
Discover carefully curated flight deals from Tampa to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:51 am -
Nonstop3h 25m
Sun 11/2212:03 pm -
Nonstop3h 24m
Deal found 9/22![Copa Airlines logo]()
$630
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:10 am -
1 stop8h 53m
Sun 12/133:29 pm -
1 stop8h 56m
Deal found 9/20![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:10 am -
1 stop8h 02m
Sat 12/268:55 am -
1 stop12h 38m
Deal found 9/19![United Airlines logo]()
$637
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:29 pm -
Nonstop3h 26m
Sat 12/126:42 pm -
Nonstop3h 18m
Deal found 9/23![Copa Airlines logo]()
$630
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:20 am -
1 stop6h 43m
Tue 12/298:00 am -
1 stop9h 15m
Deal found 9/19![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:17 am -
1 stop10h 21m
Sun 11/228:55 am -
1 stop8h 38m
Deal found 9/21![United Airlines logo]()
$645
This Justfly.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:45 pm -
2 stops25h 40m
Sat 10/247:57 pm -
2 stops17h 28m
Deal found 9/22![Multiple Airlines logo]()
$1,366
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:30 pm -
Nonstop3h 25m
Fri 11/276:42 pm -
Nonstop3h 24m
Deal found 9/23![Copa Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:00 pm -
1 stop7h 38m
Fri 1/154:41 pm -
1 stop18h 02m
Deal found 9/22![United Airlines logo]()
$645
This Copa Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/144:51 am -
Nonstop3h 26m
Sun 1/246:42 pm -
Nonstop3h 18m
Deal found 9/23![Copa Airlines logo]()
$630
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/204:51 am -
Nonstop3h 26m
Sun 1/2412:03 pm -
Nonstop3h 19m
Deal found 9/22![Copa Airlines logo]()
$630
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:18 pm -
2 stops40h 52m
Sat 10/249:50 am -
2 stops23h 44m
Deal found 9/19![United Airlines logo]()
$1,236
This Copa Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:21 am -
1 stop14h 56m
Sat 10/248:26 am -
1 stop13h 39m
Deal found 9/19![Copa Airlines logo]()
$1,037
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/227:15 am -
2 stops25h 34m
Fri 2/269:47 am -
2 stops24h 56m
Deal found 9/22![United Airlines logo]()
$1,290
Last-minute flights from Tampa to PanamaDiscover last-minute flight deals from Tampa to Panama. Data last updated September 24, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to Panama. Data last updated September 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2911:45 am -
1 stop7h 52m
Thu 11/268:55 am -
1 stop8h 38m
Deal found 9/24![United Airlines logo]()
$707
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:00 am -
1 stop12h 37m
Thu 4/87:55 am -
1 stop8h 42m
Deal found 9/21![United Airlines logo]()
$697
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:55 pm -
2 stops23h 07m
Thu 4/81:49 pm -
2 stops19h 59m
Deal found 9/21![American Airlines logo]()
$711
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:10 am -
1 stop5h 52m
Wed 4/141:49 pm -
1 stop7h 11m
Deal found 9/20![American Airlines logo]()
$708
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:50 pm -
1 stop8h 41m
Mon 10/1910:00 am -
1 stop11h 34m
Deal found 9/21![Multiple Airlines logo]()
$702
This Copa Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:21 am -
1 stop12h 04m
Sat 10/247:57 pm -
1 stop19h 29m
Deal found 9/22![Copa Airlines logo]()
$1,037
This oojo deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:21 am -
1 stop14h 56m
Sat 10/248:26 am -
2 stops26h 59m
Deal found 9/19![Multiple Airlines logo]()
$1,081
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:40 am -
1 stop11h 33m
Wed 10/286:40 am -
1 stop6h 25m
Deal found 9/23![Multiple Airlines logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:57 pm -
1 stop27h 34m
Sun 10/2510:00 am -
1 stop11h 34m
Deal found 9/22![Multiple Airlines logo]()
$736
This Avianca deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:45 pm -
1 stop18h 30m
Tue 10/276:10 pm -
1 stop19h 15m
Deal found 9/19![Avianca logo]()
$740
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
1 stop7h 45m
Sun 11/228:55 am -
1 stop12h 44m
Deal found 9/22![United Airlines logo]()
$715
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:40 am -
1 stop24h 43m
Sun 11/226:15 pm -
2 stops14h 03m
Deal found 9/22![Multiple Airlines logo]()
$718
One-way flights from Tampa to PanamaSearch for one-way flight options from Tampa to Panama. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
Search for one-way flight options from Tampa to Panama. Find affordable one-way fares based on user searches. Data last updated September 24, 2026.
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/299:30 am -
1 stop7h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![United Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/256:34 pm -
2 stops19h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![American Airlines logo]()
$291
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:35 am -
1 stop26h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/106:00 am -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:29 pm -
2 stops37h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:08 am -
2 stops24h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
1 stop24h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$336
Find flight deals from Tampa to Panama
Keep the following information in mind while searching for Tampa to Panama flight deals. Data was last updated September 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $627 (United Airlines) |
One-way from | $286 (United Airlines) |
Popular in | September |
Cheapest in | April |
Average price | $770 |
Good round-trip deal | $492 or less |
Good one-way deal | $227 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
Use the filters below to find and compare flights from Tampa to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Tue 12/1
6:20 am-2:03 pm
1 stop7h 43m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$286
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Tue 12/29
9:30 am-5:12 pm
1 stop7h 42m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$286
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Tue 11/17
11:40 am-7:38 pm
1 stop7h 58m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$296
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Sat 11/7
6:29 pm-8:31 pm
1 stop26h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$325
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Sun 11/8
7:08 am-1:46 pm
3 stops30h 38m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$415
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Tue 12/29
7:00 am-3:33 pm
1 stop8h 33m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$452
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Wed 9/30
7:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$505
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Thu 10/1
7:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$505
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Tue 12/1
9:40 am-8:07 am
3 stops22h 27m
Panama City Tocumen Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$510
TampaPanama City
TPA Tampa - PTY Panama City Tocumen Intl
TPAPTY
Tampa
Wed 11/18
4:51 am-8:16 am
Nonstop3h 25m
Panama City Tocumen Intl
Sun 11/22
12:03 pm-3:27 pm
Nonstop3h 24m
$630
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from Tampa to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Tampa with our price prediction graph.
TPA-PTY
TPA-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to Panama
TPA-PA0
TPA-PTY
TPA-DAV
What is the cheapest month to book a flight from Tampa to Panama?
Currently, April is the cheapest month in which you can book a flight from Tampa to Panama (average of $513). Flying from Tampa to Panama in September is currently the most expensive (average of $770). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TPA to PA?
Find hourly flight availability from Tampa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 24, 2026.
One of the essential ways to save on airfare from Tampa to Panama is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 12% on airfare.
Weekly flight availability from Tampa to Panama
Explore weekly flight availability from Tampa to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 24, 2026.
The most flights from TPA to PA0 are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).
How far ahead should I book a flight from Tampa to Panama?
The best time to book flights from Tampa to Panama is 16 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Tampa to Panama?
Use this chart to determine the cheapest time to fly round-trip from Tampa to Panama. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Tampa to Panama flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated September 24, 2026.
Read reviews from past customers who have flown Copa Airlines,United Airlines, andAmerican Airlines from Tampa to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Food
6.9
Overall
7.6
Boarding
7.8
Crew
8.1
Comfort
7.4
Entertainment
6.9
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Tampa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Tampa to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Tampa to Panama by cabin class
Find flights from Tampa to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and Panama flights
Browse other Tampa and Panama flight options. Last updated on September 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Tampa to Panama flights
Consider these flights traveling from Tampa to Panama.
Top 4 airlines flying from Tampa to Panama
Discover the top 4 airlines that operate flights from Tampa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$243 | Average$687 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$256 | Average$418 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$339 | Average$530 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$402 | Average$711 | FlexibilityNo cancel fee | On-time70% |