HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$159+ Cheap flights from Tampa (TPA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — PTY
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Tampa to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Tampa to Panama

Cheapest flights from Tampa to Panama
Explore the most affordable flight options available from Tampa to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amTPA - PTY
1 stop9h 42mAmerican Airlines
Fri 12/124:43 pmPTY - TPA
1 stop7h 15mAmerican Airlines
Deal found 11/26$340
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:00 amTPA - PTY
1 stop6h 47mAmerican Airlines
Tue 12/164:43 pmPTY - TPA
1 stop14h 59mAmerican Airlines
Deal found 11/26$350
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:00 amTPA - PTY
1 stop7h 42mAmerican Airlines
Sun 12/144:43 pmPTY - TPA
1 stop7h 15mAmerican Airlines
Deal found 11/26$355
This Cheapflightsfares deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:55 pmTPA - PTY
1 stop10h 05mAvianca
Mon 12/152:55 amPTY - TPA
1 stop10h 30mAvianca
Deal found 11/26$389
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:00 amTPA - PTY
1 stop8h 42mAmerican Airlines
Sun 12/144:43 pmPTY - TPA
1 stop7h 15mAmerican Airlines
Deal found 11/25$405
This Cheapflightsfares deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/12:55 pmTPA - PTY
1 stop17h 55mAvianca
Thu 4/163:20 amPTY - TPA
1 stop7h 55mAvianca
Deal found 11/25$413
This Cheapflightsfares deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/262:55 pmTPA - PTY
1 stop9h 45mAvianca
Tue 5/53:20 amPTY - TPA
1 stop7h 55mAvianca
Deal found 11/25$435
This Expedia deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:55 pmTPA - PTY
1 stop9h 45mAvianca
Thu 12/112:55 amPTY - TPA
1 stop10h 30mAvianca
Deal found 11/26$437
This Copa Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:24 pmTPA - DAV
1 stop27h 00mCopa Airlines
Sat 12/138:32 amDAV - TPA
1 stop13h 09mCopa Airlines
Deal found 11/23$1,062
This United Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:40 amTPA - DAV
2 stops31h 44mUnited Airlines
Sat 12/139:50 amDAV - TPA
1 stop26h 46mUnited Airlines
Deal found 11/23$1,272

Cheap flight deals from Tampa to Panama

Keep the following information in mind while searching for Tampa to Panama flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$239
(American Airlines)

One-way from

$159
(FlightHub)

Popular in

December

Cheapest in

September

Average price

$512

Good round-trip deal

$339 or less

Good one-way deal

$184 or less
Provider with most accurate pricing for Tampa-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa-Panama City Tocumen Intl flights.
Search Deals
From Tampa to Panama
Search Deals
One-way flight from Tampa to Panama
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Tampa to Panama.
Search Deals
Price to beat on a one-way flight from Tampa to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Tampa to Panama that are best for you.

Fly from

Tampa

Fly to

Panama

Route

Depart

Return

Price

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Thu 1/29

4:51 am-8:22 am

Nonstop3h 31m

Panama City Tocumen Intl

Thu 2/5

9:11 am-12:36 pm

Nonstop3h 25m

$385

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Thu 1/15

4:51 am-8:22 am

Nonstop3h 31m

Panama City Tocumen Intl

Sun 1/18

6:17 pm-9:41 pm

Nonstop3h 24m

$385

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Thu 1/29

4:51 am-8:22 am

Nonstop3h 31m

Panama City Tocumen Intl

Sun 2/1

6:17 pm-9:41 pm

Nonstop3h 24m

$385

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Thu 1/15

4:51 am-8:22 am

Nonstop3h 31m

Panama City Tocumen Intl

Mon 2/2

6:17 pm-9:41 pm

Nonstop3h 24m

$429

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Sun 2/8

4:51 am-8:22 am

Nonstop3h 31m

Panama City Tocumen Intl

Sun 2/22

6:17 pm-9:41 pm

Nonstop3h 24m

$429

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Sat 1/24

2:39 pm-5:55 pm

Nonstop3h 16m

Panama City Tocumen Intl

Wed 1/28

9:11 am-12:30 pm

Nonstop3h 19m

$439

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Mon 1/19

7:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-10:35 am

1 stop17h 54m

$444

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Tue 1/20

7:00 am-7:38 pm

1 stop12h 38m

Panama City Tocumen Intl

Thu 1/22

4:41 pm-10:35 am

1 stop17h 54m

$444

TampaPanama City

TPA - PTY

TPAPTY

Tampa

Tue 1/20

7:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-10:35 am

1 stop17h 54m

$444

TampaDavid

TPA - DAV

TPADAV

Tampa

Thu 2/26

6:35 am-9:04 am

2 stops26h 29m

David Enrique Malek

Sun 3/15

9:48 am-5:34 pm

2 stops30h 46m

$869

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/25

Showing 1-10 of 33 results
1
2
3
4

Best time to book a flight from Tampa to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Panama

What is the cheapest month to book a flight from Tampa to Panama?

Currently, May is the cheapest month in which you can book a flight from Tampa to Panama (average of $171). Flying from Tampa to Panama in March is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to PA?

Find hourly flight availability from Tampa to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

One of the essential ways to save on airfare from Tampa to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 52% on airfare.

What is the cheapest day to fly from Tampa to Panama?

Use this chart to determine the cheapest time to fly round-trip from Tampa to Panama. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Tampa to Panama flight should consider departing on Thursday evenings when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 26, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Tampa to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Copa Airlines
7.6
Good
1,569 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,046 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,038 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Avianca
6.6
Okay
2,477 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Tampa to Panama?

    Located just 4.9 mi from the city center, Tampa (TPA) is the airport most travelers will use when flying to Panama from Tampa.

  • How popular is this Tampa to Panama flight route?

    The Tampa to Panama flight path was viewed by 131 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Tampa to Panama?

    A quick flight from Tampa to Panama can take about 3h 31m. Copa Airlines provides one of the quickest options available for as low as $385. The distance between Tampa and Panama is about 1321 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Tampa to Panama?

    On average you can expect to pay $575 for a flight from Tampa to Panama. The cheapest flight overall is $105 while the most popular route, (Tampa - Panama City Tocumen Intl) is currently priced at $385.

  • Can I find deals for flights from Tampa to Panama that include hotel bookings?

    Yes. In addition to deals on Tampa to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Panama.

  • Can I find deals for business class flights from Tampa to Panama?

    Yes. Cheapflights offers flight deals from Tampa to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Panama?

    Currently, May is the cheapest month in which you can book a flight from Tampa to Panama (average of $171). Flying from Tampa to Panama in March is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Tampa to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Panama City flights
Miami to Managua flights
Fort Lauderdale to Guatemala City flights
Fort Lauderdale to San José flights
Miami to San Salvador flights
Orlando to San José flights
Miami to San José flights
Orlando to Panama City flights
Fort Lauderdale to Panama City flights
Tampa to Panama City flights
Miami to Guatemala City flights
Fort Lauderdale to San Salvador flights
Fort Lauderdale to San Pedro Sula flights
Orlando to Guatemala City flights
Miami to Liberia flights
Miami to San Pedro Sula flights
Tampa to San José flights
Tampa to Liberia flights
Miami to Philip S.W.Goldson flights
Tampa to Philip S.W.Goldson flights
Orlando to Philip S.W.Goldson flights
Tampa to Guatemala City flights
Jacksonville to San José flights
Fort Lauderdale to Managua flights
Fort Lauderdale to Liberia flights
Orlando to Liberia flights
Jacksonville to Panama City flights
Tampa to San Salvador flights
Miami to Coxen Hole flights
West Palm Beach to Guatemala City flights
Orlando to Managua flights
Orlando to San Pedro Sula flights
Tampa to Managua flights
Orlando to San Salvador flights
West Palm Beach to Panama City flights
Jacksonville to Liberia flights
West Palm Beach to Managua flights
Tallahassee to Panama City flights
West Palm Beach to Liberia flights
West Palm Beach to San José flights
Pensacola to Philip S.W.Goldson flights
Panama City to Panama City flights
Fort Lauderdale to Philip S.W.Goldson flights
Jacksonville to Guatemala City flights
Jacksonville to San Salvador flights
Pensacola to San José flights
Sarasota to Liberia flights
Tampa to Coxen Hole flights
Jacksonville to Philip S.W.Goldson flights
Pensacola to Managua flights

Top 5 airlines flying from Tampa to Panama

Discover the top 5 airlines that operate flights from Tampa to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$253Average$488FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$264Average$413FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$597FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$331Average$509FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$371Average$451FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.