$252+ Cheap flights from Minnesota to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Oct 28 — Nov 41
Round-trip
1 adult, Economy
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Find cheap flights from Minnesota to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minnesota to Panama
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Cheapest flights from Minnesota to PanamaExplore the most affordable flight options available from Minnesota to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
Explore the most affordable flight options available from Minnesota to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:30 pm -
2 stops21h 43m
Thu 11/263:34 pm -
1 stop9h 01m
Deal found 9/26![American Airlines logo]()
$533
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:44 pm -
1 stop24h 18m
Thu 11/268:55 am -
1 stop9h 37m
Deal found 9/26![United Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:10 pm -
2 stops20h 52m
Wed 4/71:49 pm -
2 stops21h 05m
Deal found 9/27![American Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:31 pm -
2 stops21h 41m
Fri 12/118:55 am -
1 stop15h 04m
Deal found 9/23![United Airlines logo]()
$603
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:45 pm -
1 stop24h 00m
Sat 12/1211:35 am -
1 stop12h 24m
Deal found 9/23![United Airlines logo]()
$610
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:20 am -
1 stop11h 18m
Tue 12/811:35 am -
1 stop12h 24m
Deal found 9/24![United Airlines logo]()
$613
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:40 am -
1 stop10h 57m
Wed 11/188:55 am -
1 stop15h 03m
Deal found 9/28![United Airlines logo]()
$615
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:20 am -
1 stop8h 52m
Mon 12/78:55 am -
1 stop15h 04m
Deal found 9/24![United Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:03 pm -
1 stop24h 34m
Wed 4/710:00 am -
1 stop13h 05m
Deal found 9/27![United Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:24 pm -
2 stops19h 39m
Thu 1/73:20 pm -
2 stops20h 55m
Deal found 9/24![Delta logo]()
$1,244
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:34 pm -
2 stops24h 39m
Thu 11/193:34 pm -
2 stops21h 34m
Deal found 9/28![American Airlines logo]()
$1,640
This KAYAK deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:00 am -
2 stops11h 38m
Thu 1/78:08 am -
1 stop10h 43m
Deal found 9/24![Copa Airlines logo]()
$4,055
Best flights from Minnesota to PanamaDiscover carefully curated flight deals from Minnesota to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
Discover carefully curated flight deals from Minnesota to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:51 pm -
2 stops20h 54m
Sat 12/128:55 am -
1 stop15h 04m
Deal found 9/23![United Airlines logo]()
$603
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:56 pm -
2 stops18h 17m
Mon 12/143:13 pm -
2 stops20h 35m
Deal found 9/28![American Airlines logo]()
$689
This KAYAK deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:50 am -
2 stops13h 12m
Tue 3/28:55 am -
2 stops15h 09m
Deal found 9/27![Copa Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/307:30 am -
1 stop11h 08m
Fri 12/411:35 am -
2 stops27h 37m
Deal found 9/25![United Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:24 pm -
2 stops19h 39m
Thu 1/73:20 pm -
2 stops20h 55m
Deal found 9/24![Delta logo]()
$1,244
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:51 pm -
2 stops20h 54m
Fri 12/1111:35 am -
2 stops12h 55m
Deal found 9/23![United Airlines logo]()
$603
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:40 am -
1 stop10h 57m
Thu 4/810:55 pm -
2 stops13h 09m
Deal found 9/27![United Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
2 stops13h 02m
Tue 11/178:55 am -
1 stop15h 03m
Deal found 9/26![United Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:50 am -
2 stops12h 48m
Tue 3/28:55 am -
2 stops15h 09m
Deal found 9/26![United Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/212:59 pm -
2 stops22h 46m
Mon 3/14:41 pm -
2 stops22h 47m
Deal found 9/28![United Airlines logo]()
$645
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:40 am -
1 stop10h 57m
Tue 4/610:55 pm -
2 stops15h 27m
Deal found 9/27![United Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:20 am -
1 stop11h 18m
Mon 12/1411:35 am -
1 stop12h 24m
Deal found 9/28![United Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:15 am -
1 stop13h 16m
Mon 10/263:41 pm -
1 stop18h 49m
Deal found 9/25![United Airlines logo]()
$691
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:15 am -
1 stop13h 16m
Wed 10/287:55 am -
1 stop15h 03m
Deal found 9/27![United Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:34 pm -
2 stops24h 39m
Thu 11/193:34 pm -
2 stops21h 34m
Deal found 9/28![American Airlines logo]()
$1,640
This KAYAK deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:00 am -
2 stops11h 38m
Thu 1/78:08 am -
1 stop10h 43m
Deal found 9/24![Copa Airlines logo]()
$4,055
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/215:50 am -
1 stop13h 48m
Sun 2/288:06 am -
1 stop14h 36m
Deal found 9/25![United Airlines logo]()
$4,745
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/307:00 am -
1 stop12h 37m
Thu 1/78:08 am -
1 stop14h 35m
Deal found 9/24![United Airlines logo]()
$4,895
Last-minute flights from Minnesota to PanamaDiscover last-minute flight deals from Minnesota to Panama. Data last updated September 28, 2026 and is based on user searches.
Discover last-minute flight deals from Minnesota to Panama. Data last updated September 28, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:40 am -
1 stop10h 57m
Wed 11/188:55 am -
1 stop15h 03m
Deal found 9/28![United Airlines logo]()
$615
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:12 pm -
2 stops22h 50m
Wed 10/142:02 pm -
1 stop9h 57m
Deal found 9/27![American Airlines logo]()
$655
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:10 pm -
2 stops20h 52m
Wed 4/71:49 pm -
2 stops21h 05m
Deal found 9/27![American Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Tue 10/136:03 pm -
1 stop24h 34m
Wed 4/710:00 am -
1 stop13h 05m
Deal found 9/27![United Airlines logo]()
$627
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:40 am -
1 stop10h 57m
Thu 4/810:55 pm -
1 stop15h 07m
Deal found 9/27![United Airlines logo]()
$657
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:11 pm -
2 stops17h 51m
Fri 10/232:02 pm -
1 stop9h 57m
Deal found 9/25![American Airlines logo]()
$685
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am -
2 stops13h 31m
Mon 10/263:41 pm -
1 stop18h 49m
Deal found 9/25![United Airlines logo]()
$695
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:43 pm -
2 stops23h 19m
Wed 10/282:02 pm -
1 stop9h 57m
Deal found 9/27![American Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:15 am -
1 stop13h 16m
Wed 10/287:55 am -
1 stop15h 03m
Deal found 9/27![United Airlines logo]()
$691
One-way flights from Minnesota to PanamaSearch for one-way flight options from Minnesota to Panama. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
Search for one-way flight options from Minnesota to Panama. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:45 pm -
2 stops21h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:30 am -
2 stops35h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$399
This Copa Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:45 am -
1 stop10h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Copa Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:04 am -
2 stops30h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![United Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:10 pm -
3 stops24h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:22 am -
1 stop9h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$477
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:54 pm -
3 stops24h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$745
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
1 stop31h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$794
Find flight deals from Minnesota to Panama
Keep the following information in mind while searching for Minnesota to Panama flight deals. Data was last updated September 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $533 (American Airlines) |
One-way from | $252 (United Airlines) |
Popular in | May |
Cheapest in | March |
Average price | $794 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minnesota to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
Use the filters below to find and compare flights from Minnesota to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 12/7
4:45 pm-2:45 pm
2 stops21h 00m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$252
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Fri 10/23
9:45 am-8:41 pm
1 stop10h 56m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$447
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Sun 10/4
8:04 am-2:14 pm
2 stops30h 10m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$452
Quickest round-trip
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Fri 10/23
10:22 am-7:31 pm
1 stop9h 09m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$477
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Sun 12/6
4:51 pm-2:45 pm
2 stops20h 54m
Panama City Tocumen Intl
Sat 12/12
8:55 am-10:59 pm
1 stop15h 04m
$603
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 11/30
7:30 am-7:38 pm
1 stop11h 08m
Panama City Tocumen Intl
Fri 12/4
11:35 am-2:12 pm
2 stops27h 37m
$603
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Sun 12/6
4:51 pm-2:45 pm
2 stops20h 54m
Panama City Tocumen Intl
Fri 12/11
11:35 am-11:30 pm
2 stops12h 55m
$603
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 10/12
7:40 am-6:37 pm
1 stop10h 57m
Panama City Tocumen Intl
Thu 4/8
10:55 pm-12:04 pm
2 stops13h 09m
$619
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Tue 11/10
6:00 am-8:02 pm
2 stops13h 02m
Panama City Tocumen Intl
Tue 11/17
8:55 am-10:58 pm
1 stop15h 03m
$634
DuluthPanama City
DLH Duluth Intl - PTY Panama City Tocumen Intl
DLHPTY
Duluth Intl
Sat 1/23
5:50 am-7:38 pm
2 stops12h 48m
Panama City Tocumen Intl
Tue 3/2
8:55 am-11:04 pm
2 stops15h 09m
$645
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from Minnesota to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Minnesota with our price prediction graph.
MSP-PTY
DLH-PTY
RST-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minnesota to Panama
USMN-PA0
MSP-PTY
DLH-PTY
RST-PTY
What is the cheapest month to book a flight from Minnesota to Panama?
Currently, March is the cheapest month in which you can book a flight from Minnesota to Panama (average of $724). Flying from Minnesota to Panama in May is currently the most expensive (average of $979). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Minnesota to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minnesota to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minnesota to Panama by cabin class
Find flights from Minnesota to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minnesota and Panama flights
Browse other Minnesota and Panama flight options. Last updated on September 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Panama
Find the right flight back to Minnesota after your stay in Panama
Minnesota to Panama flights
Consider these flights traveling from Minnesota to Panama.
Top 4 airlines flying from Minnesota to Panama
Discover the top 4 airlines that operate flights from Minnesota to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$577 | Average$774 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$598 | Average$794 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$636 | Average$757 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$704 | Average$904 | FlexibilityNo cancel fee | On-timeN/A |