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Panama

$244+ Cheap flights from Minnesota to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Mar 19 — Mar 261
Thu 3/19
Thu 3/26
1 adult, Economy
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Cheap flight deals from Minnesota to Panama

Cheapest flights from Minnesota to Panama
Explore the most affordable flight options available from Minnesota to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.

This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:29 pm
LSE
-
PTY
2 stops20h 32m
American Airlines
Wed 4/81:49 pm
PTY
-
LSE
2 stops19h 46m
American Airlines
Deal found 2/15$577
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:30 pm
FAR
-
PTY
2 stops19h 31m
American Airlines
Thu 4/231:49 pm
PTY
-
FAR
2 stops23h 58m
American Airlines
Deal found 2/15$577
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:48 am
MSP
-
PTY
1 stop12h 31m
Multiple Airlines
Mon 4/209:33 pm
PTY
-
MSP
2 stops26h 25m
Multiple Airlines
Deal found 2/17$615
This BusinessClass deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:28 am
MSP
-
PTY
1 stop8h 44m
Copa Airlines
Mon 8/1010:55 pm
PTY
-
MSP
1 stop11h 55m
Copa Airlines
Deal found 2/16$617
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:30 pm
FAR
-
PTY
2 stops18h 50m
American Airlines
Tue 3/241:40 pm
PTY
-
FAR
2 stops22h 07m
American Airlines
Deal found 2/16$617
This Mytrip deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:42 am
MSP
-
PTY
2 stops18h 23m
Multiple Airlines
Wed 4/155:55 pm
PTY
-
MSP
2 stops21h 43m
Multiple Airlines
Deal found 2/15$627
This BusinessClass deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
MSP
-
PTY
1 stop22h 04m
Copa Airlines
Thu 7/1610:55 pm
PTY
-
MSP
1 stop11h 55m
Copa Airlines
Deal found 2/13$628
This BusinessClass deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1311:13 am
MSP
-
PTY
1 stop16h 51m
Copa Airlines
Wed 6/247:55 am
PTY
-
MSP
1 stop9h 17m
Copa Airlines
Deal found 2/15$636
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:55 am
MSP
-
PTY
1 stop8h 39m
Multiple Airlines
Tue 4/149:33 pm
PTY
-
MSP
2 stops26h 25m
Multiple Airlines
Deal found 2/16$643
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:30 am
MSP
-
PTY
1 stop8h 42m
United Airlines
Tue 5/263:30 pm
PTY
-
MSP
1 stop19h 23m
United Airlines
Deal found 2/13$645
This Mytrip deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:24 am
MSP
-
PTY
3 stops19h 31m
Multiple Airlines
Wed 4/810:10 am
PTY
-
MSP
3 stops34h 41m
Multiple Airlines
Deal found 2/15$652
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:34 pm
FAR
-
PTY
2 stops18h 41m
American Airlines
Wed 2/252:40 pm
PTY
-
FAR
2 stops29h 19m
American Airlines
Deal found 2/16$706

Find flight deals from Minnesota to Panama

Keep the following information in mind while searching for Minnesota to Panama flight deals. Data was last updated February 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$577
(American Airlines)

One-way from

$244
(Kiwi.com)

Popular in

August

Cheapest in

July

Average price

$781
Provider with most accurate pricing for Minneapolis St Paul-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Panama City Tocumen Intl flights.
Search Deals
From Minnesota to Panama
Search Deals
One-way flight from Minnesota to Panama
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minnesota to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Minnesota to Panama that are best for you.

Fly from

Minnesota

Fly to

Panama

Route

Depart

Return

Price

La CrossePanama City

LSE - PTY

LSEPTY

La Crosse

Wed 4/1

6:29 pm-3:01 pm

2 stops20h 32m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-9:35 am

2 stops19h 46m

$577

FargoPanama City

FAR - PTY

FARPTY

Fargo Hector Field

Wed 4/1

7:30 pm-3:01 pm

2 stops19h 31m

Panama City Tocumen Intl

Thu 4/23

1:49 pm-11:57 am

2 stops22h 08m

$577

FargoPanama City

FAR - PTY

FARPTY

Fargo Hector Field

Tue 3/17

7:30 pm-2:20 pm

2 stops18h 50m

Panama City Tocumen Intl

Tue 3/24

1:40 pm-11:47 am

2 stops22h 07m

$617

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 5/19

6:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Tue 5/26

7:55 am-11:29 pm

1 stop15h 34m

$649

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 8/15

5:15 am-1:13 pm

1 stop7h 58m

Panama City Tocumen Intl

Sat 8/22

2:28 pm-12:21 am

1 stop9h 53m

$695

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 4/28

8:20 pm-1:02 pm

1 stop16h 42m

Panama City Tocumen Intl

Wed 5/6

2:27 pm-9:03 am

1 stop18h 36m

$710

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 4/28

8:20 pm-1:02 pm

1 stop16h 42m

Panama City Tocumen Intl

Tue 5/5

2:27 pm-9:08 am

1 stop18h 41m

$710

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 4/28

4:58 pm-4:04 am

1 stop11h 06m

Panama City Tocumen Intl

Tue 5/5

3:30 pm-10:21 am

2 stops18h 51m

$714

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 4/6

6:00 am-6:37 pm

2 stops12h 37m

Panama City Tocumen Intl

Tue 4/14

7:55 am-7:53 pm

2 stops11h 58m

$714

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 4/22

4:58 pm-4:04 am

1 stop11h 06m

Panama City Tocumen Intl

Tue 5/12

3:30 pm-10:21 am

2 stops18h 51m

$714

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/16

Showing 1-10 of 19 results
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Best time to book a flight from Minnesota to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Minnesota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minnesota to Panama

What is the cheapest month to book a flight from Minnesota to Panama?

Currently, September is the cheapest month in which you can book a flight from Minnesota to Panama (average of $530). Flying from Minnesota to Panama in May is currently the most expensive (average of $787). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Minnesota to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Minnesota to Panama?

    For as low as $695, American Airlines can have you in Panama from Minnesota in 7h 58m. There are 2606 mi between Minnesota and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Minnesota to Panama that include hotel bookings?

    Yes. In addition to deals on Minnesota to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minnesota to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minnesota to Panama.

  • Can I find deals for business class flights from Minnesota to Panama?

    Yes. Cheapflights offers flight deals from Minnesota to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minnesota to Panama?

    Currently, September is the cheapest month in which you can book a flight from Minnesota to Panama (average of $530). Flying from Minnesota to Panama in May is currently the most expensive (average of $787). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Minnesota to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Miami to Managua flights
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George Bush Intcntl to San José flights
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Atlanta to Guatemala City flights
Dulles Intl to Guatemala City flights
Baltimore to Panama City flights
Denver to Liberia flights
Miami to Guatemala City flights
LaGuardia to Guatemala City flights
Boston to Panama City flights

Top 4 airlines flying from Minnesota to Panama

Discover the top 4 airlines that operate flights from Minnesota to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$603Average$775FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$603Average$781FlexibilityNo cancel feeOn-time69%
DeltaCheapest$633Average$927FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$678Average$861FlexibilityNo cancel feeOn-time70%

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