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$237+ Cheap flights from Minneapolis (MSP) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Minneapolis to Panama

Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$649
(Delta)

One-way from

$237
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$825
Provider with most accurate pricing for Minneapolis St Paul-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Minneapolis St Paul-Panama City Tocumen Intl flights.
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From Minneapolis St Paul to Panama
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One-way flight from Minneapolis St Paul to Panama
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Highest demand for flights based on searches. 2% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Minneapolis to Panama

Cheapest flights from Minneapolis to Panama
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:15 amMSP - PTY
1 stop7h 34mDelta
Tue 9/302:14 pmPTY - MSP
1 stop10h 08mDelta
Deal found 4/30$649
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/233:34 pmMSP - PTY
2 stops20h 51mAmerican Airlines
Tue 9/301:50 pmPTY - MSP
2 stops19h 41mAmerican Airlines
Deal found 4/30$654
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/225:30 amMSP - PTY
2 stops26h 41mMultiple Airlines
Tue 7/299:25 amPTY - MSP
1 stop27h 52mMultiple Airlines
Deal found 4/30$682
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/18:00 amMSP - PTY
2 stops11h 31mUnited Airlines
Mon 7/710:55 pmPTY - MSP
1 stop11h 46mUnited Airlines
Deal found 4/30$906
This Gurufare deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2010:00 amMSP - PTY
3 stops26h 35mAvianca
Tue 8/261:30 pmPTY - MSP
3 stops32h 09mAvianca
Deal found 5/1$1,018
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/257:35 amMSP - DAV
2 stops33h 53mUnited Airlines
Sun 6/19:44 amDAV - MSP
2 stops47h 20mUnited Airlines
Deal found 4/30$1,303

Cheapflights Fare Finder

Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Minneapolis

Fly to

Panama

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 9/23

5:15 am-12:49 pm

1 stop7h 34m

Panama City Tocumen Intl

Tue 9/30

2:14 pm-12:22 am

1 stop10h 08m

$649

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 9/23

3:34 pm-12:25 pm

2 stops20h 51m

Panama City Tocumen Intl

Tue 9/30

1:50 pm-11:51 pm

1 stop10h 01m

$654

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 7/22

5:30 am-8:11 am

2 stops26h 41m

Panama City Tocumen Intl

Tue 7/29

9:25 am-1:17 pm

1 stop27h 52m

$682

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 6/25

7:35 am-6:37 pm

1 stop11h 02m

Panama City Tocumen Intl

Wed 7/2

3:30 pm-5:08 pm

1 stop25h 38m

$790

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 8/20

10:00 am-12:35 pm

3 stops26h 35m

Panama City Tocumen Intl

Tue 8/26

1:30 pm-9:39 pm

3 stops32h 09m

$1,018

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

Sun 5/25

7:35 am-5:28 pm

2 stops33h 53m

David Enrique Malek

Sun 6/1

9:44 am-9:04 am

2 stops47h 20m

$1,303

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 5/11

6:18 am-10:10 am

2 stops27h 52m

$237

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

Sun 5/11

7:06 am-9:00 am

2 stops25h 54m

$956

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Best time to book a flight from Minneapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama

What is the cheapest month to book a flight from Minneapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $478). Flying from Minneapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to PA?

Find hourly flight availability from Minneapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 1, 2025.
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to Panama?

    If you book a flight to Panama from Minneapolis, you will be flying from Minneapolis St Paul, which is the city’s only airport. Minneapolis St Paul (MSP) is located 7.3 mi from the center of Minneapolis.

  • Can I find deals for flights from Minneapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama.

  • Can I find deals for business class flights from Minneapolis to Panama?

    Yes. Cheapflights offers flight deals from Minneapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $478). Flying from Minneapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Minneapolis to Panama

Discover the top 3 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$615Average$783FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$649Average$781FlexibilityNo cancel feeOn-time69%
DeltaCheapest$763Average$927FlexibilityNo cancel feeOn-timeN/A

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