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$258+ Cheap flights from Minneapolis (MSP) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Mar 9 — Mar 161
Mon 3/9
Mon 3/16
1 adult, Economy
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Cheap flight deals from Minneapolis to Panama

Cheapest flights from Minneapolis to Panama
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.

This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
MSP
-
PTY
1 stop8h 20m
American Airlines
Sat 8/223:20 pm
PTY
-
MSP
2 stops19h 15m
American Airlines
Deal found 2/6$619
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:37 am
MSP
-
PTY
1 stop7h 23m
American Airlines
Sun 11/82:43 pm
PTY
-
MSP
1 stop9h 10m
American Airlines
Deal found 2/6$620
This Gurufare deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:30 am
MSP
-
PTY
1 stop11h 07m
Copa Airlines
Tue 5/127:55 am
PTY
-
MSP
1 stop14h 53m
Copa Airlines
Deal found 2/4$623
This Mytrip deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:48 am
MSP
-
PTY
2 stops24h 42m
Multiple Airlines
Sun 3/83:50 pm
PTY
-
MSP
3 stops32h 09m
Multiple Airlines
Deal found 2/4$631
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:28 am
MSP
-
PTY
1 stop8h 44m
United Airlines
Tue 6/27:55 am
PTY
-
MSP
1 stop9h 17m
United Airlines
Deal found 2/6$635
This Mytrip deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:06 am
MSP
-
PTY
2 stops17h 59m
Multiple Airlines
Wed 4/2910:10 am
PTY
-
MSP
3 stops35h 42m
Multiple Airlines
Deal found 2/4$641
This Trip.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:48 am
MSP
-
PTY
2 stops15h 12m
Multiple Airlines
Sat 3/147:50 pm
PTY
-
MSP
2 stops12h 55m
Multiple Airlines
Deal found 2/5$648
This Gurufare deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:20 am
MSP
-
DAV
2 stops24h 44m
Copa Airlines
Mon 7/276:16 pm
DAV
-
MSP
2 stops29h 43m
Copa Airlines
Deal found 2/5$1,162
This Ovago deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/257:20 am
MSP
-
DAV
2 stops24h 44m
Copa Airlines
Sun 7/269:50 am
DAV
-
MSP
2 stops25h 00m
Copa Airlines
Deal found 2/5$1,180
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:14 am
MSP
-
DAV
2 stops22h 54m
United Airlines
Fri 6/199:55 am
DAV
-
MSP
2 stops24h 18m
United Airlines
Deal found 2/5$1,213
This Gurufare deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
MSP
-
DAV
2 stops26h 04m
Copa Airlines
Tue 7/286:16 pm
DAV
-
MSP
2 stops15h 57m
Copa Airlines
Deal found 2/5$1,264
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:00 am
MSP
-
DAV
2 stops33h 31m
United Airlines
Wed 3/49:48 am
DAV
-
MSP
2 stops32h 27m
United Airlines
Deal found 2/5$1,310

Find flight deals from Minneapolis to Panama

Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated February 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$623
(Gurufare)

One-way from

$258
(Kiwi.com)

Popular in

August

Cheapest in

July

Average price

$902
Provider with most accurate pricing for Minneapolis St Paul-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Panama City Tocumen Intl flights.
Search Deals
From Minneapolis St Paul to Panama
Search Deals
One-way flight from Minneapolis St Paul to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Minneapolis

Fly to

Panama

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 5/26

7:28 am-6:37 pm

1 stop11h 09m

Panama City Tocumen Intl

Tue 6/2

7:55 am-5:12 pm

1 stop9h 17m

$635

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 4/25

7:06 am-1:55 am

3 stops18h 49m

Panama City Tocumen Intl

Wed 4/29

10:10 am-9:52 pm

3 stops35h 42m

$643

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 2/28

8:48 am-8:50 am

2 stops23h 02m

Panama City Tocumen Intl

Sat 3/14

7:50 pm-8:45 am

2 stops12h 55m

$652

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 4/22

4:58 pm-4:04 am

1 stop11h 06m

Panama City Tocumen Intl

Wed 4/29

10:00 am-10:58 pm

1 stop12h 58m

$700

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 4/21

8:13 am-7:31 pm

2 stops11h 18m

Panama City Tocumen Intl

Thu 4/30

9:45 am-12:46 am

2 stops15h 01m

$704

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 4/23

10:00 am-4:04 am

2 stops18h 04m

Panama City Tocumen Intl

Thu 4/30

10:00 am-10:48 pm

1 stop12h 48m

$704

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 4/20

7:30 am-4:12 pm

1 stop8h 42m

Panama City Tocumen Intl

Fri 5/1

7:55 am-10:48 pm

1 stop14h 53m

$720

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 4/22

7:30 am-4:12 pm

1 stop8h 42m

Panama City Tocumen Intl

Sat 5/2

7:55 am-10:59 pm

1 stop15h 04m

$720

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

Wed 2/25

7:20 am-9:04 am

2 stops24h 44m

David Enrique Malek

Mon 7/27

6:16 pm-11:59 pm

2 stops29h 43m

$1,162

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

Wed 2/25

7:20 am-9:04 am

2 stops24h 44m

David Enrique Malek

Sun 7/26

9:50 am-10:50 am

2 stops25h 00m

$1,180

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/6

Showing 1-10 of 18 results
1
2

Best time to book a flight from Minneapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama

What is the cheapest month to book a flight from Minneapolis to Panama?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $530). Flying from Minneapolis to Panama in June is currently the most expensive (average of $712). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 7, 2026.
See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Minneapolis to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,162 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,162 reviews
Delta
7.9
Good
8,162 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,556 reviews
Delta
7.9
Good
8,162 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,245 reviews
Delta
7.9
Good
8,162 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,248 reviews
Delta
7.9
Good
8,162 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to Panama?

    If you book a flight to Panama from Minneapolis, you will be flying from Minneapolis St Paul, which is the city’s only airport. Minneapolis St Paul (MSP) is located 7.3 mi from the center of Minneapolis.

  • How long is the flight from Minneapolis to Panama?

    There are many flights that can get you from Minneapolis to Panama in 11h 09m. Fly via United Airlines or Copa Airlines to get the fastest option. Minneapolis and Panama are separated by a distance of 2606 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Minneapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama.

  • Can I find deals for business class flights from Minneapolis to Panama?

    Yes. Cheapflights offers flight deals from Minneapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Panama?

    Currently, September is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $530). Flying from Minneapolis to Panama in June is currently the most expensive (average of $712). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Minneapolis to Panama

Discover the top 4 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$603Average$789FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$603Average$781FlexibilityNo cancel feeOn-time69%
DeltaCheapest$633Average$927FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$678Average$861FlexibilityNo cancel feeOn-time70%

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