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$203+ Cheap flights from Minneapolis (MSP) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
apr. 23 — apr. 301
do 4/23
do 4/30
1 adult, Economy
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Cheap flight deals from Minneapolis to Panama

Cheapest flights from Minneapolis to Panama
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on maart 24, 2026.

This Mytrip deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 4/136:18 am
MSP
-
PTY
2 stops26h 57m
Multiple Airlines
ma 5/1110:10 am
PTY
-
MSP
2 stops25h 22m
Multiple Airlines
Deal found 3/20$663
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 10/298:00 am
MSP
-
PTY
1 stop10h 38m
Copa Airlines
do 11/124:41 pm
PTY
-
MSP
1 stop18h 26m
Copa Airlines
Deal found 3/22$672
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 9/105:15 am
MSP
-
PTY
1 stop7h 41m
Delta
di 10/132:21 pm
PTY
-
MSP
1 stop10h 00m
Delta
Deal found 3/20$685
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 5/110:34 am
MSP
-
PTY
1 stop8h 54m
Multiple Airlines
zo 5/1011:59 am
PTY
-
MSP
1 stop10h 12m
Multiple Airlines
Deal found 3/19$688
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 9/107:36 am
MSP
-
PTY
1 stop11h 01m
United Airlines
di 10/1310:00 am
PTY
-
MSP
2 stops14h 42m
United Airlines
Deal found 3/20$689
This Mytrip deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 5/47:40 am
MSP
-
PTY
2 stops33h 20m
Multiple Airlines
do 5/74:25 am
PTY
-
MSP
3 stops41h 52m
Multiple Airlines
Deal found 3/19$691
This Gurufare deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 9/410:22 am
MSP
-
PTY
1 stop9h 09m
Copa Airlines
ma 9/2110:00 am
PTY
-
MSP
1 stop13h 19m
Copa Airlines
Deal found 3/21$694
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 10/298:00 am
MSP
-
PTY
1 stop10h 38m
Copa Airlines
za 11/148:55 am
PTY
-
MSP
1 stop9h 08m
Copa Airlines
Deal found 3/22$696
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 5/47:40 am
MSP
-
PTY
1 stop8h 29m
Multiple Airlines
ma 5/1111:59 am
PTY
-
MSP
1 stop10h 27m
Multiple Airlines
Deal found 3/20$699
This KAYAK deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 11/16:30 am
MSP
-
DAV
2 stops24h 20m
Copa Airlines
ma 11/308:32 am
DAV
-
MSP
2 stops25h 32m
Copa Airlines
Deal found 3/22$1,086
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 5/2610:14 am
MSP
-
DAV
2 stops22h 44m
United Airlines
za 5/309:38 am
DAV
-
MSP
2 stops37h 51m
United Airlines
Deal found 3/19$1,245
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 3/267:30 am
MSP
-
DAV
2 stops25h 34m
United Airlines
di 4/710:05 am
DAV
-
MSP
2 stops36h 53m
United Airlines
Deal found 3/22$1,365

Find flight deals from Minneapolis to Panama

Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated maart 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$663
(Mytrip)

One-way from

$203
(Kiwi.com)

Popular in

August

Cheapest in

July

Average price

$724
Provider with most accurate pricing for Minneapolis St Paul-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Panama City Tocumen Intl flights.
Search Deals
From Minneapolis St Paul to Panama
Search Deals
One-way flight from Minneapolis St Paul to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maart 24, 2026.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

do 9/10

5:15 am-12:56 pm

1 stop7h 41m

Panama City Tocumen Intl

di 10/13

2:21 pm-12:21 am

1 stop10h 00m

$685

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

do 9/10

7:36 am-6:37 pm

1 stop11h 01m

Panama City Tocumen Intl

di 10/13

10:00 am-12:42 am

2 stops14h 42m

$689

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

wo 7/29

10:14 am-7:31 pm

1 stop9h 17m

Panama City Tocumen Intl

za 8/22

10:55 pm-9:11 am

1 stop10h 16m

$710

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

zo 8/9

8:30 pm-2:14 pm

2 stops17h 44m

Panama City Tocumen Intl

zo 8/23

10:55 pm-9:11 am

1 stop10h 16m

$714

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

di 5/26

10:14 am-8:58 am

2 stops22h 44m

David Enrique Malek

za 5/30

9:38 am-11:29 pm

2 stops37h 51m

$1,245

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

vr 5/8

7:30 am-8:58 am

2 stops25h 28m

David Enrique Malek

di 5/12

9:38 am-10:53 am

2 stops25h 15m

$1,385
Cheapest one-way

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

do 5/7

9:39 pm-9:15 am

3 stops35h 36m

$269

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

do 7/23

4:14 pm-12:14 pm

2 stops20h 00m

$375
Quickest one-way

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

do 7/23

5:20 am-1:05 pm

1 stop7h 45m

$375

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

do 7/23

9:52 am-8:41 pm

1 stop10h 49m

$395

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Minneapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama

What is the cheapest month to book a flight from Minneapolis to Panama?

Currently, January is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $543). Flying from Minneapolis to Panama in May is currently the most expensive (average of $786). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated maart 24, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Minneapolis to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,325 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,325 reviews
Delta
7.9
Good
8,325 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,577 reviews
Delta
7.9
Good
8,325 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,474 reviews
Delta
7.9
Good
8,325 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,491 reviews
Delta
7.9
Good
8,325 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Food

7.2

Overall

7.9

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to Panama?

    If you book a flight to Panama from Minneapolis, you will be flying from Minneapolis St Paul, which is the city’s only airport. Minneapolis St Paul (MSP) is located 7.3 mi from the center of Minneapolis.

  • How long is the flight from Minneapolis to Panama?

    There are many flights that can get you from Minneapolis to Panama in 7h 41m. Fly via Delta or United Airlines to get the fastest option. Minneapolis and Panama are separated by a distance of 2606 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Minneapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama.

  • Can I find deals for business class flights from Minneapolis to Panama?

    Yes. Cheapflights offers flight deals from Minneapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Panama?

    Currently, January is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $543). Flying from Minneapolis to Panama in May is currently the most expensive (average of $786). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Minneapolis to Panama

Discover the top 4 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated maart 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$603Average$775FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$603Average$781FlexibilityNo cancel feeOn-time69%
DeltaCheapest$613Average$958FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$646Average$774FlexibilityNo cancel feeOn-time70%

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