HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$261+ Cheap flights from Minneapolis (MSP) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Minneapolis to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Minneapolis to Panama

Cheapest flights from Minneapolis to Panama
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:18 amMSP - PTY
2 stops16h 22mMultiple Airlines
Fri 11/219:33 pmPTY - MSP
1 stop18h 09mMultiple Airlines
Deal found 10/28$685
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:18 amMSP - PTY
1 stop12h 02mMultiple Airlines
Sat 12/68:40 amPTY - MSP
2 stops15h 29mMultiple Airlines
Deal found 10/30$724
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:12 amMSP - PTY
2 stops30h 48mMultiple Airlines
Sun 11/232:55 pmPTY - MSP
3 stops27h 49mMultiple Airlines
Deal found 10/30$749
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:29 amMSP - PTY
1 stop7h 52mDelta
Tue 12/93:46 pmPTY - MSP
1 stop9h 53mDelta
Deal found 10/29$764
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/27:32 pmMSP - PTY
2 stops17h 15mAmerican Airlines
Tue 12/92:50 pmPTY - MSP
1 stop8h 59mAmerican Airlines
Deal found 10/30$768

Cheap flight deals from Minneapolis to Panama

Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated October 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$596
(Kiwi.com)

One-way from

$261
(Kiwi.com)

Popular in

August

Cheapest in

July

Average price

$809
Provider with most accurate pricing for Minneapolis St Paul-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Panama City Tocumen Intl flights.
Search Deals
From Minneapolis St Paul to Panama
Search Deals
One-way flight from Minneapolis St Paul to Panama
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Minneapolis

Fly to

Panama

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 2/16

8:15 pm-2:02 pm

1 stop16h 47m

Panama City Tocumen Intl

Tue 2/24

3:27 pm-12:25 am

1 stop9h 58m

$604

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 2/9

7:35 am-5:07 pm

1 stop8h 32m

Panama City Tocumen Intl

Tue 2/17

8:55 am-10:59 pm

1 stop15h 04m

$604

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 2/16

7:35 am-7:38 pm

1 stop11h 03m

Panama City Tocumen Intl

Mon 2/23

11:35 am-10:59 pm

1 stop12h 24m

$604

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 2/8

6:15 pm-1:55 pm

1 stop18h 40m

Panama City Tocumen Intl

Thu 2/19

3:27 pm-9:14 am

1 stop18h 47m

$604

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 2/10

7:35 am-5:07 pm

1 stop8h 32m

Panama City Tocumen Intl

Tue 2/17

8:55 am-10:59 pm

1 stop15h 04m

$604

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 2/4

6:00 am-8:02 pm

2 stops13h 02m

Panama City Tocumen Intl

Wed 2/18

4:41 pm-8:55 am

2 stops17h 14m

$608

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 2/9

6:00 am-8:02 pm

2 stops13h 02m

Panama City Tocumen Intl

Wed 2/18

4:41 pm-8:55 am

2 stops17h 14m

$608

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 2/4

6:00 am-8:02 pm

2 stops13h 02m

Panama City Tocumen Intl

Mon 2/16

4:41 pm-10:23 am

2 stops18h 42m

$608

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 2/5

7:35 am-5:07 pm

1 stop8h 32m

Panama City Tocumen Intl

Tue 2/17

4:41 pm-8:55 am

2 stops17h 14m

$608

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 2/8

6:30 pm-2:45 pm

2 stops19h 15m

Panama City Tocumen Intl

Thu 2/19

4:41 pm-8:55 am

2 stops17h 14m

$608

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 19 results
1
2

Best time to book a flight from Minneapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama

What is the cheapest month to book a flight from Minneapolis to Panama?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $530). Flying from Minneapolis to Panama in June is currently the most expensive (average of $712). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to PA?

Find hourly flight availability from Minneapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s typically best to fly out from Minneapolis to Panama in the evening. Doing so could potentially save you 79% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 30, 2025.
See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Minneapolis to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Copa Airlines
7.6
Good
1,563 reviews
Delta
7.9
Good
7,993 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,993 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,993 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to Panama?

    If you book a flight to Panama from Minneapolis, you will be flying from Minneapolis St Paul, which is the city’s only airport. Minneapolis St Paul (MSP) is located 7.3 mi from the center of Minneapolis.

  • How long is the flight from Minneapolis to Panama?

    There are many flights that can get you from Minneapolis to Panama in 8h 32m. Fly via Delta or United Airlines to get the fastest option. Minneapolis and Panama are separated by a distance of 2606 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Minneapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama.

  • Can I find deals for business class flights from Minneapolis to Panama?

    Yes. Cheapflights offers flight deals from Minneapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Panama?

    Currently, September is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $530). Flying from Minneapolis to Panama in June is currently the most expensive (average of $712). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Minneapolis to Panama

Discover the top 4 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$603Average$787FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$607Average$820FlexibilityNo cancel feeOn-time69%
DeltaCheapest$653Average$927FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$719Average$1,066FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.