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$315+ Cheap flights from Minneapolis (MSP) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
ago. 5 — ago. 121
mar. 8/5
mar. 8/12
1 adult, Economy
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Cheap flight deals from Minneapolis to Panama

Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated julio 31, 2025.

Round-trip from

$511
(Mytrip)

One-way from

$315
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$955
From Minneapolis St Paul to Panama
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One-way flight from Minneapolis St Paul to Panama
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Minneapolis to Panama

Cheapest flights from Minneapolis to Panama
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 31, 2025.

This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/127:00 amMSP - PTY
2 stops25h 55mMultiple Airlines
vie. 9/1910:05 pmPTY - MSP
3 stops34h 21mMultiple Airlines
Deal found 7/30$511
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/136:00 amMSP - PTY
2 stops12h 38mUnited Airlines
mar. 11/254:41 pmPTY - MSP
1 stop19h 08mUnited Airlines
Deal found 7/30$583
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/145:15 amMSP - PTY
1 stop13h 46mDelta
sáb. 11/223:17 pmPTY - MSP
1 stop10h 05mDelta
Deal found 7/30$633
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/235:45 pmMSP - PTY
2 stops19h 10mAmerican Airlines
mar. 9/301:45 pmPTY - MSP
1 stop9h 03mAmerican Airlines
Deal found 7/29$653
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/148:00 amMSP - DAV
2 stops24h 58mUnited Airlines
dom. 9/219:42 amDAV - MSP
2 stops37h 31mUnited Airlines
Deal found 7/31$1,036

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.

Fly from

Minneapolis

Fly to

Panama

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

vie. 9/12

7:00 am-8:55 am

2 stops25h 55m

Panama City Tocumen Intl

vie. 9/19

10:05 pm-8:26 am

3 stops34h 21m

$511

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

jue. 11/13

6:00 am-7:38 pm

2 stops12h 38m

Panama City Tocumen Intl

mar. 11/25

4:41 pm-10:49 am

1 stop19h 08m

$583

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

lun. 1/5

6:07 am-1:10 pm

1 stop30h 03m

Panama City Tocumen Intl

sáb. 1/24

4:40 pm-12:35 am

1 stop8h 55m

$618

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

vie. 11/14

6:10 pm-1:52 pm

1 stop18h 42m

Panama City Tocumen Intl

dom. 11/23

8:05 am-3:31 pm

1 stop8h 26m

$633

MinneapolisDavid

MSP - DAV

MSPDAV

Minneapolis St Paul

dom. 9/14

8:00 am-8:58 am

2 stops24h 58m

David Enrique Malek

dom. 9/21

9:42 am-11:13 pm

2 stops37h 31m

$1,036

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

vie. 8/15

7:18 am-12:45 am

3 stops17h 27m

$315

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

lun. 12/29

6:45 pm-5:07 pm

2 stops21h 22m

$324

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

mar. 12/30

3:15 pm-8:02 pm

1 stop27h 47m

$342

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

mié. 12/24

10:20 am-1:20 pm

2 stops26h 00m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Minneapolis to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama

What is the cheapest month to book a flight from Minneapolis to Panama?

Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $478). Flying from Minneapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to PA?

Find hourly flight availability from Minneapolis to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated julio 31, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Minneapolis to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,902 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to Panama?

    If you book a flight to Panama from Minneapolis, you will be flying from Minneapolis St Paul, which is the city’s only airport. Minneapolis St Paul (MSP) is located 7.3 mi from the center of Minneapolis.

  • What are the cheapest airlines to fly from Minneapolis to Panama one-way?

    The cheapest airlines for a one-way flight from Minneapolis to Panama are United Airlines ($324), Delta ($342), and American Airlines ($385).

  • Can I find deals for flights from Minneapolis to Panama that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama.

  • Can I find deals for business class flights from Minneapolis to Panama?

    Yes. Cheapflights offers flight deals from Minneapolis to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Panama?

    Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $478). Flying from Minneapolis to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Minneapolis to Panama

Discover the top 3 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$562Average$780FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$648Average$796FlexibilityNo cancel feeOn-time69%
DeltaCheapest$698Average$924FlexibilityNo cancel feeOn-timeN/A

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