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$172+ Cheap flights from Louisiana to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Find flight deals from Louisiana to Panama

Cheapest flights from Louisiana to Panama
Explore the most affordable flight options available from Louisiana to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:29 amMSY - PTY
1 stop7h 13mAmerican Airlines
Fri 12/124:43 pmPTY - MSY
1 stop8h 34mAmerican Airlines
Deal found 11/3$392
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:15 amMSY - PTY
1 stop8h 30mUnited Airlines
Tue 12/1611:35 amPTY - MSY
1 stop12h 24mUnited Airlines
Deal found 11/5$412
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:02 pmMSY - PTY
2 stops20h 40mAmerican Airlines
Fri 12/122:50 pmPTY - MSY
1 stop10h 27mAmerican Airlines
Deal found 11/5$416
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:40 pmMSY - PTY
2 stops20h 02mAmerican Airlines
Sun 12/142:50 pmPTY - MSY
2 stops20h 56mAmerican Airlines
Deal found 11/5$421
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:15 amMSY - PTY
1 stop13h 44mDelta
Fri 12/123:46 pmPTY - MSY
1 stop7h 32mDelta
Deal found 11/3$432
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:45 pmMSY - PTY
2 stops20h 57mAmerican Airlines
Sat 12/204:55 pmPTY - MSY
1 stop17h 13mAmerican Airlines
Deal found 11/4$443
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:29 amMSY - PTY
1 stop7h 13mAmerican Airlines
Tue 12/164:43 pmPTY - MSY
2 stops18h 15mAmerican Airlines
Deal found 11/5$446
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1611:50 amMSY - PTY
1 stop6h 48mUnited Airlines
Sat 12/204:41 pmPTY - MSY
1 stop7h 47mUnited Airlines
Deal found 11/4$465
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amMSY - PTY
1 stop6h 47mAmerican Airlines
Fri 12/122:50 pmPTY - MSY
1 stop10h 27mAmerican Airlines
Deal found 11/3$486
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1412:10 pmBTR - PTY
1 stop25h 35mUnited Airlines
Mon 1/124:41 pmPTY - BTR
1 stop24h 17mUnited Airlines
Deal found 11/5$566
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:05 amSHV - PTY
1 stop7h 07mDelta
Wed 11/193:37 pmPTY - SHV
1 stop8h 51mDelta
Deal found 11/3$612
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:27 pmBTR - PTY
2 stops21h 15mAmerican Airlines
Mon 1/124:50 pmPTY - BTR
2 stops25h 11mAmerican Airlines
Deal found 11/5$646

Cheap flight deals from Louisiana to Panama

Keep the following information in mind while searching for Louisiana to Panama flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$392
(American Airlines)

One-way from

$172
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$518
Provider with most accurate pricing for New Orleans Louis Armstrong-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Panama City Tocumen Intl flights.
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From Louisiana to Panama
Search Deals
One-way flight from Louisiana to Panama
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Louisiana to Panama that are best for you.

Fly from

Louisiana

Fly to

Panama

Route

Depart

Return

Price

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Thu 12/4

6:40 pm-1:47 pm

2 stops18h 07m

Panama City Tocumen Intl

Fri 12/12

2:50 pm-10:05 am

2 stops20h 15m

$396

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Sun 4/5

7:30 pm-2:14 pm

1 stop18h 44m

Panama City Tocumen Intl

Tue 4/7

3:20 pm-8:55 am

1 stop17h 35m

$398

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Mon 4/20

5:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

Sat 5/2

2:20 pm-11:23 pm

1 stop9h 03m

$412

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Mon 4/13

5:20 am-2:14 pm

1 stop8h 54m

Panama City Tocumen Intl

Fri 4/17

10:00 am-7:50 pm

1 stop9h 50m

$412

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Fri 12/5

6:02 pm-3:42 pm

2 stops20h 40m

Panama City Tocumen Intl

Fri 12/12

2:50 pm-12:17 am

1 stop10h 27m

$416

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Thu 12/11

6:40 pm-3:42 pm

2 stops20h 02m

Panama City Tocumen Intl

Sun 12/14

2:50 pm-10:46 am

2 stops20h 56m

$421

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Mon 4/20

3:21 pm-12:15 pm

2 stops20h 54m

Panama City Tocumen Intl

Sat 5/2

1:55 pm-9:42 am

2 stops19h 47m

$426

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Fri 12/5

5:15 am-7:59 pm

1 stop13h 44m

Panama City Tocumen Intl

Fri 12/12

3:46 pm-10:18 pm

1 stop7h 32m

$432

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Sat 12/6

5:15 am-7:59 pm

1 stop13h 44m

Panama City Tocumen Intl

Fri 12/12

3:46 pm-10:18 pm

1 stop7h 32m

$432

New OrleansPanama City

MSY - PTY

MSYPTY

New Orleans Louis Armstrong

Wed 1/14

9:05 am-7:38 pm

1 stop9h 33m

Panama City Tocumen Intl

Wed 2/11

4:41 pm-10:58 pm

1 stop7h 17m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 42 results
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Best time to book a flight from Louisiana to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Panama

What is the cheapest month to book a flight from Louisiana to Panama?

Currently, September is the cheapest month in which you can book a flight from Louisiana to Panama (average of $346). Flying from Louisiana to Panama in January is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LA to PA?

Find hourly flight availability from Louisiana to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

It’s typically best to fly out from Louisiana to Panama at noon. Doing so could potentially save you 41% on the flight price compared to flying in the afternoon, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisiana to Panama?

    For as low as $412, American Airlines can have you in Panama from Louisiana in 7h 25m. The distance from Louisiana to Panama is about 1606 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Louisiana to Panama that include hotel bookings?

    Yes. In addition to deals on Louisiana to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Panama.

  • Can I find deals for business class flights from Louisiana to Panama?

    Yes. Cheapflights offers flight deals from Louisiana to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Panama?

    Currently, September is the cheapest month in which you can book a flight from Louisiana to Panama (average of $346). Flying from Louisiana to Panama in January is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Louisiana to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Louisiana to Panama

Discover the top 3 airlines that operate flights from Louisiana to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$489FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$613FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$526FlexibilityNo cancel feeOn-timeN/A

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