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$772+ Cheap flights from Islip, NY (ISP) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
ISP — PTY
feb. 7 — feb. 141
sáb. 2/7
sáb. 2/14
1 adult, Economy
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Cheap flight deals from Islip to Panama

Keep the following information in mind while searching for Islip to Panama flight deals. Data was last updated enero 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$771
(Expedia)

Popular in

December

Cheapest in

September

Average price

$618
Provider with most accurate pricing for New York (NYC)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for New York (NYC)-Panama City Tocumen Intl flights.
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From Islip Long Island to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Islip to Panama

Cheapest flights from Islip to Panama
Explore the most affordable flight options available from Islip to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2111:41 amISP - PTY
1 stop8h 46mMultiple Airlines
sáb. 2/289:40 amPTY - ISP
1 stop9h 48mMultiple Airlines
Deal found 1/6$772
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 1/2812:25 pmISP - PTY
2 stops44h 25mMultiple Airlines
dom. 2/19:45 amPTY - ISP
2 stops49h 48mMultiple Airlines
Deal found 1/8$774
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/138:22 pmISP - PTY
2 stops29h 38mMultiple Airlines
dom. 3/152:55 amPTY - ISP
2 stops15h 32mMultiple Airlines
Deal found 1/8$787
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/81:07 pmISP - PTY
2 stops33h 03mMultiple Airlines
lun. 4/1311:05 amPTY - ISP
2 stops52h 14mMultiple Airlines
Deal found 1/8$884
This Kiwi.com deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/97:25 amISP - PTY
1 stop13h 16mMultiple Airlines
jue. 1/152:55 amPTY - ISP
2 stops17h 14mMultiple Airlines
Deal found 1/8$1,337

Cheapflights Fare Finder

 
Customize your flight search to find flights from Islip to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 8, 2026.
Use the filters below to find and compare flights from Islip to Panama that are best for you.

Fly from

Islip

Fly to

Panama

Route

Depart

Return

Price

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

sáb. 2/21

11:41 am-8:27 pm

1 stop8h 46m

Panama City Tocumen Intl

sáb. 2/28

9:40 am-7:28 pm

1 stop9h 48m

$772

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

mié. 1/28

12:25 pm-8:50 am

2 stops44h 25m

Panama City Tocumen Intl

dom. 2/1

9:45 am-11:33 am

2 stops49h 48m

$774

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

vie. 3/13

8:22 pm-1:00 am

2 stops29h 38m

Panama City Tocumen Intl

dom. 3/15

2:55 am-7:27 pm

2 stops15h 32m

$787

IslipPanama City

ISP - PTY

ISPPTY

Islip Long Island

mié. 4/8

1:07 pm-9:10 pm

2 stops33h 03m

Panama City Tocumen Intl

lun. 4/13

11:05 am-4:19 pm

2 stops52h 14m

$884

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Best time to book a flight from Islip to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Islip with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Islip to Panama

What is the cheapest month to book a flight from Islip, New York to Panama?

Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama (average of $201). Flying from Islip, New York to Panama in January is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Islip to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Islip to Panama?

    Located just 7.2 mi from the city center, Islip Long Island (ISP) is the airport most travelers will use when flying to Panama from Islip.

  • Can I find deals for flights from Islip to Panama that include hotel bookings?

    Yes. In addition to deals on Islip to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Islip to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Islip to Panama.

  • Can I find deals for business class flights from Islip to Panama?

    Yes. Cheapflights offers flight deals from Islip to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Islip, New York to Panama?

    Currently, July is the cheapest month in which you can book a flight from Islip, New York to Panama (average of $201). Flying from Islip, New York to Panama in January is currently the most expensive (average of $451). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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