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Panama

$174+ Cheap flights from Columbus to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
jan 17 — jan 241
sáb 1/17
sáb 1/24
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on dezembro 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/194:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
seg 12/228:55 amPTY - CMH
1 stop14h 34mUnited Airlines
Deal found 12/17$644
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/256:10 amCMH - PTY
1 stop13h 28mUnited Airlines
seg 12/2911:35 amPTY - CMH
1 stop11h 54mUnited Airlines
Deal found 12/16$666
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 12/194:15 pmCMH - PTY
2 stops22h 30mUnited Airlines
ter 12/238:55 amPTY - CMH
2 stops14h 49mUnited Airlines
Deal found 12/17$730
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 12/2511:08 amCMH - PTY
2 stops26h 45mAmerican Airlines
seg 12/294:55 pmPTY - CMH
1 stop17h 42mAmerican Airlines
Deal found 12/17$770
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 12/274:45 pmCMH - PTY
1 stop22h 00mUnited Airlines
qua 6/243:20 pmPTY - CMH
1 stop18h 39mUnited Airlines
Deal found 12/16$832

Find flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated dezembro 18, 2025.

Round-trip from

$414
(United Airlines)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$1,258
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($177 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($58 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 18, 2025.
Use the filters below to find and compare flights from Columbus to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

seg 1/19

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

qui 1/29

8:55 am-10:29 pm

1 stop13h 34m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

seg 1/19

6:30 am-5:07 pm

1 stop10h 37m

Panama City Tocumen Intl

qua 1/28

4:41 pm-11:04 am

1 stop18h 23m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

seg 4/6

9:30 am-7:31 pm

1 stop11h 01m

Panama City Tocumen Intl

seg 4/13

7:55 am-10:15 pm

1 stop13h 20m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

seg 1/19

7:10 pm-1:27 pm

2 stops18h 17m

Panama City Tocumen Intl

qui 1/29

4:50 pm-12:44 am

1 stop7h 54m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

qua 3/4

6:30 am-2:45 pm

1 stop8h 15m

Panama City Tocumen Intl

dom 3/8

9:30 am-8:10 pm

1 stop9h 40m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

qua 1/21

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

dom 1/25

4:41 pm-11:04 am

1 stop18h 23m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

qui 1/22

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

dom 1/25

4:41 pm-11:04 am

1 stop18h 23m

$431

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

sex 1/30

6:30 am-5:07 pm

1 stop10h 37m

Panama City Tocumen Intl

seg 2/2

8:55 am-10:29 pm

1 stop13h 34m

$431

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

qua 4/29

11:40 am-9:08 am

2 stops22h 28m

David Enrique Malek

sáb 5/2

9:55 am-10:44 am

2 stops23h 49m

$1,000

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

qua 1/28

3:00 pm-1:27 pm

2 stops22h 27m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 17 results
1
2

Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama

What is the cheapest month to book a flight from Columbus to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus to Panama (average of $330). Flying from Columbus to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated dezembro 18, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 27% on flights from Columbus to Panama by exploring options for tickets at noon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated dezembro 18, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,004 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,055 reviews
Delta
7.9
Good
8,004 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to Panama?

    Departing from Columbus to Panama will take you 13h 08m. Airlines will cover a distance of 2146 mi.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus to Panama (average of $330). Flying from Columbus to Panama in December is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to Panama

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated dezembro 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$548FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$632FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$585FlexibilityNo cancel feeOn-time69%

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