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Panama

$174+ Cheap flights from Columbus to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Find flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:37 amCMH - PTY
1 stop8h 01mUnited Airlines
Mon 12/228:55 amPTY - CMH
1 stop14h 34mUnited Airlines
Deal found 10/31$414
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amCMH - PTY
1 stop13h 59mDelta
Sat 12/63:46 pmPTY - CMH
1 stop8h 17mDelta
Deal found 11/1$448
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:20 amCMH - PTY
1 stop8h 25mUnited Airlines
Sat 12/611:35 amPTY - CMH
2 stops21h 55mUnited Airlines
Deal found 11/1$452
This Avianca Connect deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/298:30 amCMH - PTY
2 stops16h 30mMultiple Airlines
Fri 12/52:55 amPTY - CMH
2 stops19h 19mMultiple Airlines
Deal found 11/1$594
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/315:58 pmCMH - PTY
2 stops20h 47mUnited Airlines
Mon 11/38:55 amPTY - CMH
1 stop13h 17mUnited Airlines
Deal found 10/31$636

Cheap flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated November 2, 2025.

Round-trip from

$414
(United Airlines)

One-way from

$174
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$585
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($186 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Columbus to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:45 am-2:14 pm

1 stop8h 29m

Panama City Tocumen Intl

Mon 4/6

10:55 pm-9:54 am

1 stop9h 59m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Sun 4/5

7:55 pm-12:55 pm

1 stop18h 00m

Panama City Tocumen Intl

Tue 4/7

2:20 pm-9:01 am

1 stop17h 41m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 12/15

11:37 am-7:38 pm

1 stop8h 01m

Panama City Tocumen Intl

Mon 12/22

8:55 am-11:29 pm

1 stop14h 34m

$414

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

3:13 pm-1:27 pm

2 stops22h 14m

Panama City Tocumen Intl

Wed 1/28

2:27 pm-9:15 am

2 stops18h 48m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:00 am-4:12 pm

2 stops11h 12m

Panama City Tocumen Intl

Tue 4/7

7:55 am-9:50 pm

1 stop12h 55m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 1/27

11:22 am-8:02 pm

1 stop8h 40m

Panama City Tocumen Intl

Mon 2/2

4:41 pm-9:50 am

2 stops17h 09m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 1/19

5:35 am-8:02 pm

2 stops14h 27m

Panama City Tocumen Intl

Wed 1/28

4:41 pm-11:03 am

1 stop18h 22m

$418

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 1/22

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

Mon 1/26

4:41 pm-1:22 pm

2 stops20h 41m

$418

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Tue 3/3

12:05 pm-9:04 am

2 stops20h 59m

David Enrique Malek

Fri 3/6

9:48 am-11:04 am

2 stops25h 16m

$1,000

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 4/2

6:00 am-6:37 pm

2 stops13h 37m

$174

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Showing 1-10 of 11 results
1
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Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama

What is the cheapest month to book a flight from Columbus to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus to Panama (average of $330). Flying from Columbus to Panama in December is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 27% on flights from Columbus to Panama by exploring options for tickets at noon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 2, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,997 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,997 reviews
Delta
7.9
Good
7,997 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,994 reviews
Delta
7.9
Good
7,997 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,997 reviews

Boarding

8.2

Crew

8.5

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to Panama?

    Departing from Columbus to Panama will take you 8h 40m. Airlines will cover a distance of 2146 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus to Panama (average of $330). Flying from Columbus to Panama in December is currently the most expensive (average of $496). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$393Average$567FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$579FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$548FlexibilityNo cancel feeOn-time69%

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