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Panama

$185+ Cheap flights from Columbus to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:39 am
CMH
-
PTY
1 stop7h 58m
United Airlines
Wed 4/2210:00 am
PTY
-
CMH
1 stop11h 03m
United Airlines
Deal found 1/29$435
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/49:00 am
CMH
-
PTY
1 stop11h 02m
United Airlines
Mon 3/93:41 pm
PTY
-
CMH
1 stop29h 34m
United Airlines
Deal found 1/27$444
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:43 pm
CMH
-
PTY
1 stop19h 57m
American Airlines
Fri 3/64:05 pm
PTY
-
CMH
1 stop8h 54m
American Airlines
Deal found 1/29$445
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3011:38 am
CMH
-
PTY
1 stop8h 53m
United Airlines
Sun 5/310:00 am
PTY
-
CMH
1 stop11h 11m
United Airlines
Deal found 1/28$452
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:20 am
CMH
-
PTY
1 stop10h 42m
United Airlines
Thu 3/267:55 am
PTY
-
CMH
1 stop13h 20m
United Airlines
Deal found 1/26$454
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:30 am
CMH
-
PTY
2 stops14h 32m
United Airlines
Sun 3/810:55 pm
PTY
-
CMH
2 stops16h 51m
United Airlines
Deal found 1/28$456
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:10 am
CMH
-
PTY
1 stop10h 57m
United Airlines
Sat 3/78:55 am
PTY
-
CMH
1 stop13h 20m
United Airlines
Deal found 1/27$469
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:30 am
CMH
-
PTY
1 stop13h 08m
United Airlines
Tue 3/173:41 pm
PTY
-
CMH
1 stop18h 20m
United Airlines
Deal found 1/28$478
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:10 am
CMH
-
DAV
2 stops35h 21m
United Airlines
Tue 3/39:48 am
DAV
-
CMH
2 stops36h 24m
United Airlines
Deal found 1/26$860
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:15 am
CMH
-
DAV
2 stops36h 16m
United Airlines
Tue 3/319:56 am
DAV
-
CMH
2 stops24h 01m
United Airlines
Deal found 1/28$877
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:45 am
CMH
-
DAV
2 stops11h 50m
United Airlines
Wed 8/269:50 am
DAV
-
CMH
2 stops35h 00m
United Airlines
Deal found 1/28$1,006
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:30 am
CMH
-
DAV
2 stops36h 01m
United Airlines
Fri 3/209:48 am
DAV
-
CMH
2 stops28h 58m
United Airlines
Deal found 1/27$1,359

Find flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated January 29, 2026.

Round-trip from

$435
(United Airlines)

One-way from

$185
(Delta)

Popular in

December

Cheapest in

October

Average price

$572
From Columbus to Panama
Search Deals
One-way flight from Columbus to Panama
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($229 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($80 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Columbus to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

11:39 am-6:37 pm

1 stop7h 58m

Panama City Tocumen Intl

Wed 4/22

10:00 am-10:03 pm

1 stop11h 03m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 4/15

11:39 am-6:37 pm

1 stop7h 58m

Panama City Tocumen Intl

Mon 4/20

7:55 am-10:03 pm

1 stop13h 08m

$435

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Mon 3/2

6:38 pm-1:40 pm

2 stops19h 02m

Panama City Tocumen Intl

Fri 3/6

4:05 pm-11:38 am

2 stops19h 33m

$439

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Thu 3/19

6:38 pm-12:40 pm

2 stops19h 02m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-9:04 am

2 stops18h 24m

$439

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Wed 3/4

5:30 am-8:02 pm

2 stops14h 32m

Panama City Tocumen Intl

Mon 3/9

3:41 pm-1:22 pm

2 stops20h 41m

$439

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Tue 3/3

6:10 am-9:04 am

2 stops26h 54m

David Enrique Malek

Tue 3/17

9:48 am-11:01 am

2 stops24h 13m

$860

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Tue 2/24

6:10 am-5:31 pm

2 stops35h 21m

David Enrique Malek

Tue 3/3

9:48 am-10:12 pm

2 stops36h 24m

$860

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Sun 3/22

6:15 am-5:31 pm

2 stops36h 16m

David Enrique Malek

Tue 3/31

9:56 am-10:57 am

2 stops24h 01m

$877

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

Fri 3/13

6:30 am-5:31 pm

2 stops36h 01m

David Enrique Malek

Fri 3/20

9:48 am-3:46 pm

2 stops28h 58m

$1,359

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

Tue 3/24

6:00 am-2:20 pm

2 stops9h 20m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 17 results
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Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama

What is the cheapest month to book a flight from Columbus to Panama?

Currently, May is the cheapest month in which you can book a flight from Columbus to Panama (average of $330). Flying from Columbus to Panama in February is currently the most expensive (average of $518). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,215 reviews
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,205 reviews
Delta
7.9
Good
8,128 reviews

Food

7.2

Boarding

8.1

Comfort

7.9

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to Panama?

    Departing from Columbus to Panama will take you 7h 58m. Airlines will cover a distance of 2146 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Panama?

    Currently, May is the cheapest month in which you can book a flight from Columbus to Panama (average of $330). Flying from Columbus to Panama in February is currently the most expensive (average of $518). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$359Average$509FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$574FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$430Average$584FlexibilityNo cancel feeOn-time69%

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