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Panama

$191+ Cheap flights from Columbus to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — PTY
oct. 15 — oct. 221
mer. 10/15
mer. 10/22
1 adult, Economy
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Cheap flight deals from Columbus to Panama

Keep the following information in mind while searching for Columbus to Panama flight deals. Data was last updated septembre 15, 2025.

Round-trip from

$413
(United Airlines)

One-way from

$191
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$528
From Columbus to Panama
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One-way flight from Columbus to Panama
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Highest demand for flights based on searches. 17% potential increase in price ($129 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Columbus to Panama

Cheapest flights from Columbus to Panama
Explore the most affordable flight options available from Columbus to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:15 amCMH - PTY
1 stop8h 59mUnited Airlines
lun. 10/203:30 pmPTY - CMH
1 stop18h 29mUnited Airlines
Deal found 9/15$413
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/244:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
jeu. 11/278:55 amPTY - CMH
1 stop11h 03mUnited Airlines
Deal found 9/13$422
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/135:59 pmCMH - PTY
2 stops21h 04mAmerican Airlines
lun. 10/203:15 pmPTY - CMH
2 stops19h 13mAmerican Airlines
Deal found 9/13$435
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/196:15 amCMH - PTY
1 stop13h 22mUnited Airlines
sam. 10/259:45 amPTY - CMH
1 stop10h 20mUnited Airlines
Deal found 9/13$447
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 11/84:45 pmCMH - PTY
1 stop26h 53mUnited Airlines
sam. 11/154:41 pmPTY - CMH
1 stop18h 14mUnited Airlines
Deal found 9/15$457
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/246:36 pmCMH - PTY
2 stops19h 07mAmerican Airlines
jeu. 11/272:43 pmPTY - CMH
2 stops19h 40mAmerican Airlines
Deal found 9/13$468
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 10/155:30 amCMH - PTY
2 stops9h 33mAmerican Airlines
mar. 10/213:15 pmPTY - CMH
2 stops18h 43mAmerican Airlines
Deal found 9/14$481
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 12/145:30 amCMH - PTY
2 stops10h 07mAmerican Airlines
jeu. 12/184:56 pmPTY - CMH
1 stop8h 01mAmerican Airlines
Deal found 9/14$485
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 10/86:15 amCMH - DAV
2 stops27h 43mUnited Airlines
lun. 10/209:44 amDAV - CMH
2 stops33h 51mUnited Airlines
Deal found 9/15$916

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 15, 2025.
Use the filters below to find and compare flights from Columbus to Panama that are best for you.

Fly from

Columbus

Fly to

Panama

Route

Depart

Return

Price

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 10/29

7:05 am-12:56 pm

1 stop6h 51m

Panama City Tocumen Intl

mer. 11/5

3:21 pm-10:46 pm

1 stop7h 25m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 10/15

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

lun. 10/20

3:30 pm-10:59 am

1 stop18h 29m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 10/28

7:05 am-12:56 pm

1 stop6h 51m

Panama City Tocumen Intl

mar. 11/4

3:21 pm-11:59 pm

1 stop8h 38m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 10/14

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

mer. 10/22

10:00 am-10:15 pm

1 stop11h 15m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 10/14

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

mar. 10/21

3:30 pm-10:59 am

1 stop18h 29m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 10/15

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

mer. 10/22

10:00 am-10:15 pm

1 stop11h 15m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mer. 10/15

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

mar. 10/21

9:45 am-10:02 pm

1 stop11h 17m

$413

ColumbusPanama City

CMH - PTY

CMHPTY

Columbus

mar. 10/28

6:30 am-6:38 pm

1 stop13h 08m

Panama City Tocumen Intl

mar. 11/4

8:55 am-11:44 pm

2 stops14h 49m

$418

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

mer. 10/8

6:15 am-8:58 am

2 stops27h 43m

David Enrique Malek

lun. 10/20

9:44 am-10:59 am

2 stops24h 15m

$916

ColumbusDavid

CMH - DAV

CMHDAV

Columbus

mar. 3/3

6:30 am-5:31 pm

2 stops11h 01m

David Enrique Malek

ven. 3/6

9:48 am-7:36 pm

2 stops33h 48m

$999

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 17 results
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Best time to book a flight from Columbus to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus to Panama

What is the cheapest month to book a flight from Columbus to Panama?

Currently, October is the cheapest month in which you can book a flight from Columbus to Panama (average of $478). Flying from Columbus to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CMH to PA?

Find hourly flight availability from Columbus to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septembre 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbus to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated septembre 15, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Columbus to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Columbus to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Columbus to Panama?

    Departing from Columbus to Panama will take you 6h 51m. Airlines will cover a distance of 2146 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbus to Panama that include hotel bookings?

    Yes. In addition to deals on Columbus to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Panama.

  • Can I find deals for business class flights from Columbus to Panama?

    Yes. Cheapflights offers flight deals from Columbus to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus to Panama?

    Currently, October is the cheapest month in which you can book a flight from Columbus to Panama (average of $478). Flying from Columbus to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbus to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Columbus to Panama

Discover the top 3 airlines that operate flights from Columbus to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$375Average$568FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$430Average$548FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$450Average$577FlexibilityNo cancel feeOn-time71%

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