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$198+ Cheap flights from Colorado to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from Colorado to Panama

Keep the following information in mind while searching for Colorado to Panama flight deals. Data was last updated August 16, 2025.

Round-trip from

$462
(Trip.com)

One-way from

$198
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$574

Good round-trip deal

$438 or less

Good one-way deal

$172 or less
From Colorado to Panama
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One-way flight from Colorado to Panama
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Highest demand for flights based on searches. 5% potential increase in price ($37 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Colorado to Panama.
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Price to beat on a one-way flight from Colorado to Panama.
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Find flight deals from Colorado to Panama

Cheapest flights from Colorado to Panama
Explore the most affordable flight options available from Colorado to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Trip.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Thu 9/189:33 pmPTY - DEN
1 stop11h 57mMultiple Airlines
Deal found 8/14$462
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:34 amDEN - PTY
1 stop9h 06mMultiple Airlines
Thu 11/69:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 8/16$470
This Trip.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1012:59 amDEN - PTY
2 stops14h 37mMultiple Airlines
Thu 9/188:10 amPTY - DEN
1 stop25h 20mMultiple Airlines
Deal found 8/14$484
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/56:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Sun 9/79:33 pmPTY - DEN
1 stop11h 57mMultiple Airlines
Deal found 8/16$496
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:55 pmDEN - PTY
1 stop12h 16mMultiple Airlines
Sun 10/129:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 8/15$498
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:34 amDEN - PTY
1 stop9h 06mMultiple Airlines
Sat 11/89:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 8/15$500
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:34 amDEN - PTY
1 stop16h 46mMultiple Airlines
Sun 11/169:33 pmPTY - DEN
1 stop13h 00mMultiple Airlines
Deal found 8/13$508
This Copa Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Sun 11/1612:56 pmPTY - DEN
Nonstop6h 21mCopa Airlines
Deal found 8/14$513
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1212:34 amDEN - PTY
1 stop9h 06mMultiple Airlines
Fri 10/179:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 8/15$515
This Kiwi.com deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1212:34 amDEN - PTY
1 stop9h 06mMultiple Airlines
Thu 10/169:33 pmPTY - DEN
1 stop12h 00mMultiple Airlines
Deal found 8/15$517
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1711:01 amCOS - PTY
2 stops26h 30mAmerican Airlines
Thu 9/253:31 pmPTY - COS
2 stops21h 20mAmerican Airlines
Deal found 8/13$608
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/277:30 amCOS - PTY
2 stops10h 07mUnited Airlines
Sat 10/410:00 amPTY - COS
2 stops12h 54mUnited Airlines
Deal found 8/13$628

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Colorado to Panama that are best for you.

Fly from

Colorado

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 11/1

12:34 am-10:40 am

1 stop9h 06m

Panama City Tocumen Intl

Thu 11/6

9:33 pm-8:33 am

1 stop13h 00m

$470

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 9/5

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Sun 9/7

9:33 pm-8:30 am

1 stop11h 57m

$496

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 10/3

6:55 pm-8:11 am

1 stop12h 16m

Panama City Tocumen Intl

Sun 10/12

9:33 pm-8:33 am

1 stop12h 00m

$498

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 11/1

12:34 am-10:40 am

1 stop9h 06m

Panama City Tocumen Intl

Sat 11/8

9:33 pm-8:33 am

1 stop13h 00m

$500

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 11/13

9:36 pm-5:33 am

Nonstop5h 57m

Panama City Tocumen Intl

Mon 11/17

12:56 pm-5:17 pm

Nonstop6h 21m

$513

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 11/7

9:36 pm-5:33 am

Nonstop5h 57m

Panama City Tocumen Intl

Sun 11/16

12:56 pm-5:17 pm

Nonstop6h 21m

$513

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 10/12

12:34 am-10:40 am

1 stop9h 06m

Panama City Tocumen Intl

Fri 10/17

9:33 pm-8:33 am

1 stop12h 00m

$515

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 8/29

12:34 am-4:26 pm

1 stop14h 52m

Panama City Tocumen Intl

Sat 9/13

9:33 pm-8:30 am

1 stop11h 57m

$520

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 11/10

12:59 am-1:52 pm

1 stop10h 53m

Panama City Tocumen Intl

Mon 11/17

3:17 pm-11:47 pm

1 stop10h 30m

$527

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 11/22

9:05 pm-6:49 pm

1 stop19h 44m

Panama City Tocumen Intl

Thu 11/27

3:35 pm-10:11 am

1 stop20h 36m

$527

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/15

Showing 1-10 of 24 results
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Best time to book a flight from Colorado to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama

What is the cheapest month to book a flight from Colorado to Panama?

Currently, October is the cheapest month in which you can book a flight from Colorado to Panama (average of $478). Flying from Colorado to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PA?

Find hourly flight availability from Colorado to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to Panama as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Panama flight route?

    The Colorado to Panama flight path was viewed by 34 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • Can I find deals for flights from Colorado to Panama that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama.

  • Can I find deals for business class flights from Colorado to Panama?

    Yes. Cheapflights offers flight deals from Colorado to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama?

    Currently, October is the cheapest month in which you can book a flight from Colorado to Panama (average of $478). Flying from Colorado to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Colorado to Panama

Discover the top 4 airlines that operate flights from Colorado to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$473Average$644FlexibilityNo cancel feeOn-time70%
DeltaCheapest$491Average$683FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$491Average$642FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$675FlexibilityNo cancel feeOn-time69%

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