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$183+ Cheap flights from Colorado to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Nov 19 — Nov 261
Wed 11/19
Wed 11/26
1 adult, Economy
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Find flight deals from Colorado to Panama

Cheapest flights from Colorado to Panama
Explore the most affordable flight options available from Colorado to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/211:25 pmDEN - PTY
1 stop13h 05mMultiple Airlines
Tue 12/96:11 pmPTY - DEN
1 stop16h 32mMultiple Airlines
Deal found 10/18$498
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:25 pmDEN - PTY
1 stop14h 30mMultiple Airlines
Thu 12/1110:25 amPTY - DEN
2 stops13h 34mMultiple Airlines
Deal found 10/20$517
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:34 amDEN - PTY
1 stop13h 20mMultiple Airlines
Wed 11/269:33 pmPTY - DEN
1 stop15h 43mMultiple Airlines
Deal found 10/18$522
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:34 amDEN - PTY
1 stop13h 20mMultiple Airlines
Wed 11/269:33 pmPTY - DEN
1 stop15h 43mMultiple Airlines
Deal found 10/18$532
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:36 pmDEN - PTY
Nonstop5h 57mCopa Airlines
Thu 1/1512:56 pmPTY - DEN
Nonstop6h 20mCopa Airlines
Deal found 10/19$548
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:34 amDEN - PTY
1 stop13h 20mMultiple Airlines
Sat 11/229:33 pmPTY - DEN
1 stop13h 30mMultiple Airlines
Deal found 10/19$553
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:25 pmDEN - PTY
1 stop27h 24mUnited Airlines
Thu 1/154:41 pmPTY - DEN
1 stop9h 00mUnited Airlines
Deal found 10/18$554
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/141:42 pmDEN - PTY
2 stops16h 48mMultiple Airlines
Sat 11/229:33 pmPTY - DEN
1 stop13h 30mMultiple Airlines
Deal found 10/19$559
This Kiwi.com deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:29 pmDEN - PTY
1 stop28h 51mMultiple Airlines
Mon 12/291:45 pmPTY - DEN
1 stop22h 18mMultiple Airlines
Deal found 10/17$562
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:30 amCOS - PTY
1 stop10h 08mUnited Airlines
Wed 12/108:55 amPTY - COS
1 stop14h 55mUnited Airlines
Deal found 10/19$584
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:59 pmCOS - PTY
2 stops20h 43mAmerican Airlines
Sat 12/274:55 pmPTY - COS
2 stops24h 59mAmerican Airlines
Deal found 10/19$670
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:37 amCOS - PTY
2 stops25h 10mAmerican Airlines
Sat 12/274:55 pmPTY - COS
2 stops24h 59mAmerican Airlines
Deal found 10/19$700

Cheap flight deals from Colorado to Panama

Keep the following information in mind while searching for Colorado to Panama flight deals. Data was last updated October 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$498
(Kiwi.com)

One-way from

$183
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$586

Good round-trip deal

$466 or less

Good one-way deal

$174 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
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From Colorado to Panama
Search Deals
One-way flight from Colorado to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Colorado to Panama.
Search Deals
Price to beat on a one-way flight from Colorado to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
Use the filters below to find and compare flights from Colorado to Panama that are best for you.

Fly from

Colorado

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Wed 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 2/28

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 3/8

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

9:48 pm-5:33 am

Nonstop5h 45m

Panama City Tocumen Intl

Mon 3/9

12:56 pm-6:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$535

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/6

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Tue 1/13

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 1/9

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 1/18

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 1/1

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sun 1/18

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 3/1

7:45 am-5:07 pm

1 stop7h 22m

Panama City Tocumen Intl

Mon 3/9

7:55 am-7:54 pm

1 stop12h 59m

$550

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Wed 12/3

7:30 am-7:38 pm

1 stop10h 08m

Panama City Tocumen Intl

Wed 12/10

8:55 am-9:50 pm

1 stop14h 55m

$584

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Wed 12/3

12:45 pm-3:42 pm

2 stops24h 57m

Panama City Tocumen Intl

Wed 12/10

4:43 pm-9:55 am

2 stops19h 12m

$588

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/19

Showing 1-10 of 31 results
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Best time to book a flight from Colorado to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama

What is the cheapest month to book a flight from Colorado to Panama?

Currently, March is the cheapest month in which you can book a flight from Colorado to Panama (average of $354). Flying from Colorado to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PA?

Find hourly flight availability from Colorado to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 20, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 61% on flights from Colorado to Panama by exploring options for tickets in the evening.

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Panama flight route?

    The Colorado to Panama flight path was viewed by 30 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Panama?

    Copa Airlines, United Airlines, and American Airlines can get you from Colorado to Panama in just under 5h 55m. Your travel time can differ by up to 19h 02m. The distance between Colorado and Panama is about 2634 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Colorado to Panama that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama.

  • Can I find deals for business class flights from Colorado to Panama?

    Yes. Cheapflights offers flight deals from Colorado to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama?

    Currently, March is the cheapest month in which you can book a flight from Colorado to Panama (average of $354). Flying from Colorado to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Colorado to Panama

Discover the top 4 airlines that operate flights from Colorado to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$487Average$650FlexibilityNo cancel feeOn-time70%
DeltaCheapest$518Average$924FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$667FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$754FlexibilityNo cancel feeOn-time69%

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