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$184+ Cheap flights from Colorado to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheap flight deals from Colorado to Panama

Cheapest flights from Colorado to Panama
Explore the most affordable flight options available from Colorado to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:45 amDEN - PTY
1 stop9h 53mUnited Airlines
Wed 12/318:55 amPTY - DEN
1 stop16h 49mUnited Airlines
Deal found 12/9$678
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:45 amDEN - PTY
1 stop9h 53mUnited Airlines
Mon 1/194:41 pmPTY - DEN
1 stop21h 03mUnited Airlines
Deal found 12/7$682
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:35 pmDEN - PTY
1 stop18h 32mUnited Airlines
Wed 1/288:55 amPTY - DEN
1 stop13h 00mUnited Airlines
Deal found 12/8$690
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:05 pmDEN - PTY
1 stop15h 40mUnited Airlines
Tue 12/304:41 pmPTY - DEN
1 stop17h 37mUnited Airlines
Deal found 12/7$703
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:45 amDEN - PTY
1 stop7h 22mUnited Airlines
Wed 1/74:41 pmPTY - DEN
1 stop9h 00mUnited Airlines
Deal found 12/8$721
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:02 amDEN - PTY
1 stop7h 43mUnited Airlines
Tue 12/2311:35 amPTY - DEN
1 stop12h 31mUnited Airlines
Deal found 12/8$728
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:35 pmDEN - PTY
1 stop18h 32mUnited Airlines
Thu 1/154:41 pmPTY - DEN
1 stop18h 14mUnited Airlines
Deal found 12/8$729
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2911:35 pmDEN - PTY
2 stops14h 19mAmerican Airlines
Thu 1/84:50 pmPTY - DEN
2 stops21h 59mAmerican Airlines
Deal found 12/7$735
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:45 pmCOS - PTY
2 stops24h 57mAmerican Airlines
Mon 12/154:43 pmPTY - COS
2 stops21h 03mAmerican Airlines
Deal found 12/7$738
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:47 pmDEN - PTY
1 stop23h 00mAmerican Airlines
Wed 1/282:27 pmPTY - DEN
1 stop11h 27mAmerican Airlines
Deal found 12/8$739
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:38 pmDEN - PTY
1 stop14h 16mAmerican Airlines
Fri 1/94:50 pmPTY - DEN
2 stops23h 08mAmerican Airlines
Deal found 12/7$760
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:00 amDEN - PTY
1 stop10h 07mUnited Airlines
Sun 12/284:41 pmPTY - DEN
1 stop16h 00mUnited Airlines
Deal found 12/7$763

Find flight deals from Colorado to Panama

Keep the following information in mind while searching for Colorado to Panama flight deals. Data was last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$548
(Copa Airlines)

One-way from

$184
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$739

Good round-trip deal

$447 or less

Good one-way deal

$198 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
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From Colorado to Panama
Search Deals
One-way flight from Colorado to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Colorado to Panama.
Search Deals
Price to beat on a one-way flight from Colorado to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Colorado to Panama that are best for you.

Fly from

Colorado

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 2/9

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Thu 2/19

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Sat 2/28

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/20

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Tue 2/24

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 4/11

5:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Sun 4/19

10:00 am-8:13 pm

1 stop11h 13m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 3/27

6:17 am-4:07 pm

1 stop8h 50m

Panama City Tocumen Intl

Sun 4/5

7:55 am-8:13 pm

1 stop13h 18m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 4/29

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Mon 5/4

12:56 pm-6:25 pm

Nonstop6h 29m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/27

5:01 am-2:45 pm

1 stop7h 44m

Panama City Tocumen Intl

Thu 2/5

4:41 pm-11:41 pm

1 stop9h 00m

$563

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/27

5:00 am-5:07 pm

1 stop10h 07m

Panama City Tocumen Intl

Sun 3/8

11:35 am-11:44 pm

1 stop13h 09m

$563

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/27

5:01 am-7:38 pm

1 stop12h 37m

Panama City Tocumen Intl

Wed 2/4

4:41 pm-11:41 pm

1 stop9h 00m

$563

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/13

8:33 pm-5:07 pm

1 stop18h 34m

Panama City Tocumen Intl

Thu 2/19

8:55 am-4:33 pm

1 stop9h 38m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 22 results
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Best time to book a flight from Colorado to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama

What is the cheapest month to book a flight from Colorado to Panama?

Currently, March is the cheapest month in which you can book a flight from Colorado to Panama (average of $354). Flying from Colorado to Panama in December is currently the most expensive (average of $529). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PA?

Find hourly flight availability from Colorado to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 9, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 62% on flights from Colorado to Panama by exploring options for tickets in the afternoon.

Weekly flight availability from Colorado to Panama

Explore weekly flight availability from Colorado to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 9, 2025.

The most flights from USCO to PA0 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Panama flight route?

    The Colorado to Panama flight path was viewed by 38 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Panama?

    Copa Airlines and United Airlines can get you from Colorado to Panama in just under 5h 55m. Your travel time can differ by up to 2h 19m. The distance between Colorado and Panama is about 2634 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Colorado to Panama that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama.

  • Can I find deals for business class flights from Colorado to Panama?

    Yes. Cheapflights offers flight deals from Colorado to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama?

    Currently, March is the cheapest month in which you can book a flight from Colorado to Panama (average of $354). Flying from Colorado to Panama in December is currently the most expensive (average of $529). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Colorado to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Colorado to Panama

Discover the top 4 airlines that operate flights from Colorado to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$477Average$646FlexibilityNo cancel feeOn-time70%
DeltaCheapest$527Average$947FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$527Average$650FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$753FlexibilityNo cancel feeOn-time69%

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