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Panama

$148+ Cheap flights from Colorado to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — PTY
Feb 24 — Mar 31
Tue 2/24
Tue 3/3
1 adult, Economy
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Cheap flight deals from Colorado to Panama

Cheapest flights from Colorado to Panama
Explore the most affordable flight options available from Colorado to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 25, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop16h 01m
Multiple Airlines
Tue 5/53:20 am
PTY
-
DEN
2 stops34h 38m
Multiple Airlines
Deal found 1/23$477
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2911:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Sat 5/23:20 am
PTY
-
DEN
2 stops34h 38m
Multiple Airlines
Deal found 1/23$488
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:05 pm
DEN
-
PTY
1 stop10h 29m
Multiple Airlines
Sat 4/253:20 am
PTY
-
DEN
2 stops34h 38m
Multiple Airlines
Deal found 1/23$497
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:15 am
DEN
-
PTY
2 stops17h 30m
Multiple Airlines
Tue 5/59:33 pm
PTY
-
DEN
1 stop13h 57m
Multiple Airlines
Deal found 1/23$502
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop16h 01m
Multiple Airlines
Tue 5/55:25 pm
PTY
-
DEN
2 stops18h 05m
Multiple Airlines
Deal found 1/23$511
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:25 pm
DEN
-
PTY
1 stop9h 15m
Multiple Airlines
Sat 3/79:45 am
PTY
-
DEN
2 stops28h 07m
Multiple Airlines
Deal found 1/24$517
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:05 pm
DEN
-
PTY
1 stop16h 01m
Multiple Airlines
Mon 5/49:33 pm
PTY
-
DEN
1 stop13h 57m
Multiple Airlines
Deal found 1/23$520
This Expedia deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3011:15 am
DEN
-
PTY
2 stops21h 15m
Multiple Airlines
Fri 2/611:25 am
PTY
-
DEN
3 stops25h 11m
Multiple Airlines
Deal found 1/23$533
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/74:38 pm
DEN
-
PTY
2 stops19h 22m
Multiple Airlines
Mon 2/236:15 pm
PTY
-
DEN
1 stop16h 06m
Multiple Airlines
Deal found 1/24$537
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:25 pm
DEN
-
PTY
1 stop14h 41m
Multiple Airlines
Tue 3/105:50 pm
PTY
-
DEN
2 stops15h 36m
Multiple Airlines
Deal found 1/24$540
This Mytrip deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:45 am
DEN
-
PTY
2 stops17h 10m
Avianca
Mon 4/203:50 pm
PTY
-
DEN
2 stops17h 36m
Avianca
Deal found 1/24$541
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:25 pm
DEN
-
PTY
1 stop14h 41m
Multiple Airlines
Mon 3/95:50 pm
PTY
-
DEN
2 stops15h 36m
Multiple Airlines
Deal found 1/24$543

Find flight deals from Colorado to Panama

Keep the following information in mind while searching for Colorado to Panama flight deals. Data was last updated January 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$477
(Kiwi.com)

One-way from

$148
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$630

Good round-trip deal

$410 or less

Good one-way deal

$273 or less
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
Search Deals
From Colorado to Panama
Search Deals
One-way flight from Colorado to Panama
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Colorado to Panama.
Search Deals
Price to beat on a one-way flight from Colorado to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Colorado to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 25, 2026.
Use the filters below to find and compare flights from Colorado to Panama that are best for you.

Fly from

Colorado

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/3

11:25 pm-10:40 am

1 stop9h 15m

Panama City Tocumen Intl

Sat 3/7

9:45 am-11:52 am

2 stops28h 07m

$517

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 4/25

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Wed 4/29

12:56 pm-6:25 pm

Nonstop6h 29m

$576

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Tue 3/31

7:35 am-4:12 pm

1 stop7h 37m

Panama City Tocumen Intl

Tue 4/7

10:00 am-9:31 pm

1 stop12h 31m

$585

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 4/20

10:51 pm-5:33 am

Nonstop5h 42m

Panama City Tocumen Intl

Fri 5/1

12:56 pm-6:25 pm

Nonstop6h 29m

$589

Colorado SpringsPanama City

COS - PTY

COSPTY

Colorado Springs

Mon 4/6

5:13 pm-2:14 pm

2 stops20h 01m

Panama City Tocumen Intl

Mon 4/13

10:00 am-9:31 pm

1 stop12h 31m

$589

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 4/24

12:55 am-1:02 pm

1 stop11h 07m

Panama City Tocumen Intl

Wed 4/29

2:27 pm-12:33 am

1 stop11h 06m

$591

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 5/5

7:45 am-4:12 pm

1 stop7h 27m

Panama City Tocumen Intl

Fri 5/8

7:55 am-10:15 pm

1 stop15h 20m

$591

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Mon 5/11

5:10 am-4:12 pm

1 stop10h 02m

Panama City Tocumen Intl

Fri 5/22

10:00 am-10:15 pm

1 stop13h 15m

$591

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 5/1

5:10 am-4:12 pm

1 stop10h 02m

Panama City Tocumen Intl

Sun 5/17

10:00 am-8:16 pm

1 stop11h 16m

$591

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 5/3

7:45 am-4:12 pm

1 stop7h 27m

Panama City Tocumen Intl

Fri 5/8

7:55 am-8:16 pm

1 stop13h 21m

$591

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/22

Showing 1-10 of 31 results
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Best time to book a flight from Colorado to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Panama

What is the cheapest month to book a flight from Colorado to Panama?

Currently, March is the cheapest month in which you can book a flight from Colorado to Panama (average of $354). Flying from Colorado to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to PA?

Find hourly flight availability from Colorado to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 25, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Colorado to Panama as you normally would.

Weekly flight availability from Colorado to Panama

Explore weekly flight availability from Colorado to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 25, 2026.

The most flights from USCO to PA0 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Colorado to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Colorado to Panama flight route?

    The Colorado to Panama flight path was viewed by 32 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Colorado to Panama?

    Copa Airlines and United Airlines can get you from Colorado to Panama in just under 5h 42m. Your travel time can differ by up to 1h 55m. The distance between Colorado and Panama is about 2634 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Colorado to Panama that include hotel bookings?

    Yes. In addition to deals on Colorado to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Panama.

  • Can I find deals for business class flights from Colorado to Panama?

    Yes. Cheapflights offers flight deals from Colorado to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Panama?

    Currently, March is the cheapest month in which you can book a flight from Colorado to Panama (average of $354). Flying from Colorado to Panama in June is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Colorado to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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John F Kennedy Intl to San José flights
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Hobby to San José flights
Fort Lauderdale to San José flights
Hobby to San Pedro Sula flights
Reagan-National to San Salvador flights
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Boston to Panama City flights
George Bush Intcntl to San Pedro Sula flights
Dallas/Fort Worth to San José flights
Miami to San Salvador flights
LaGuardia to Liberia flights
Dallas/Fort Worth to Guatemala City flights
Atlanta to San José flights
Miami to San José flights
Orlando to Panama City flights
Dulles Intl to Guatemala City flights
George Bush Intcntl to San José flights
Boston to San José flights
Orlando to San José flights
Reagan-National to San José flights
Fort Lauderdale to Panama City flights
Boston to Liberia flights
Denver to Liberia flights
LaGuardia to Guatemala City flights

Top 3 airlines flying from Colorado to Panama

Discover the top 3 airlines that operate flights from Colorado to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$469Average$627FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$473Average$642FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$510Average$672FlexibilityNo cancel feeOn-time69%

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