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$273+ Cheap flights from Cleveland (CLE) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from Cleveland to Panama

Keep the following information in mind while searching for Cleveland to Panama flight deals. Data was last updated July 1, 2025.

Round-trip from

$489
(American Airlines)

One-way from

$273
(United Airlines)

Popular in

December

Cheapest in

November

Average price

$700
From Cleveland Hopkins Intl to Panama
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One-way flight from Cleveland Hopkins Intl to Panama
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Highest demand for flights based on searches. 2% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Cleveland to Panama

Cheapest flights from Cleveland to Panama
Explore the most affordable flight options available from Cleveland to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:00 amCLE - PTY
1 stop9h 31mAmerican Airlines
Tue 9/161:45 pmPTY - CLE
1 stop8h 05mAmerican Airlines
Deal found 6/29$489
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:30 pmCLE - PTY
1 stop13h 41mMultiple Airlines
Thu 8/218:01 amPTY - CLE
1 stop11h 41mMultiple Airlines
Deal found 6/30$506
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:00 amCLE - PTY
1 stop7h 55mDelta
Tue 9/302:10 pmPTY - CLE
1 stop9h 29mDelta
Deal found 6/29$509
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:22 pmCLE - PTY
1 stop25h 15mUnited Airlines
Mon 8/183:30 pmPTY - CLE
1 stop18h 57mUnited Airlines
Deal found 6/29$520
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/148:50 amCLE - PTY
2 stops37h 20mAvianca
Thu 8/218:10 pmPTY - CLE
3 stops45h 47mAvianca
Deal found 6/30$1,036

Cheapflights Fare Finder

Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Cleveland

Fly to

Panama

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 9/12

6:00 am-2:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Tue 9/16

1:45 pm-10:50 pm

1 stop8h 05m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 8/14

7:30 pm-8:11 am

1 stop13h 41m

Panama City Tocumen Intl

Thu 8/21

8:01 am-8:42 pm

1 stop11h 41m

$506

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 9/27

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Tue 9/30

2:10 pm-12:39 am

1 stop9h 29m

$509

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 8/4

6:22 pm-6:37 pm

1 stop25h 15m

Panama City Tocumen Intl

Mon 8/18

3:30 pm-11:27 am

1 stop18h 57m

$520

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 8/14

8:50 am-9:10 pm

2 stops37h 20m

Panama City Tocumen Intl

Thu 8/21

8:10 pm-6:57 pm

3 stops45h 47m

$1,036

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 7/8

6:20 am-6:37 pm

1 stop13h 17m

$273

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 7/7

4:30 pm-12:54 pm

2 stops21h 24m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Cleveland to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama

What is the cheapest month to book a flight from Cleveland to Panama?

Currently, October is the cheapest month in which you can book a flight from Cleveland to Panama (average of $478). Flying from Cleveland to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to PA?

Find hourly flight availability from Cleveland to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Cleveland to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 1, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Cleveland to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,363 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cleveland to Panama?

    Cleveland Hopkins Intl (CLE) is the airport you will fly out of if you book a flight from Cleveland to Panama. It is only a 10.1 mi journey to Hopkins Intl (CLE) from Cleveland’s city center.

  • Can I find deals for flights from Cleveland to Panama that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama.

  • Can I find deals for business class flights from Cleveland to Panama?

    Yes. Cheapflights offers flight deals from Cleveland to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama?

    Currently, October is the cheapest month in which you can book a flight from Cleveland to Panama (average of $478). Flying from Cleveland to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cleveland to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Cleveland to Panama

Discover the top 3 airlines that operate flights from Cleveland to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$367Average$571FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$384Average$615FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$615FlexibilityNo cancel feeOn-time69%

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