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Panama

$243+ Cheap flights from Cleveland (CLE) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Cleveland to Panama

Cheapest flights from Cleveland to Panama
Explore the most affordable flight options available from Cleveland to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
CLE
-
PTY
1 stop13h 37m
United Airlines
Thu 4/93:30 pm
PTY
-
CLE
1 stop18h 55m
United Airlines
Deal found 1/27$511
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/317:55 pm
CLE
-
PTY
2 stops14h 35m
Multiple Airlines
Wed 2/47:50 pm
PTY
-
CLE
2 stops14h 01m
Multiple Airlines
Deal found 1/27$512
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:48 pm
CLE
-
PTY
2 stops19h 57m
American Airlines
Thu 4/91:49 pm
PTY
-
CLE
2 stops21h 48m
American Airlines
Deal found 1/27$515
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:15 am
CLE
-
PTY
1 stop8h 59m
United Airlines
Mon 3/3010:55 pm
PTY
-
CLE
1 stop10h 17m
United Airlines
Deal found 1/27$531
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:50 pm
CLE
-
PTY
2 stops21h 46m
American Airlines
Fri 5/81:49 pm
PTY
-
CLE
2 stops21h 30m
American Airlines
Deal found 1/28$535
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:22 pm
CLE
-
PTY
1 stop7h 40m
United Airlines
Sun 3/2210:55 pm
PTY
-
CLE
1 stop9h 52m
United Airlines
Deal found 1/27$538
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:01 pm
CLE
-
PTY
2 stops13h 49m
Multiple Airlines
Thu 3/1910:25 am
PTY
-
CLE
1 stop11h 09m
Multiple Airlines
Deal found 1/27$547
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:22 pm
CLE
-
PTY
1 stop19h 19m
American Airlines
Thu 4/21:40 pm
PTY
-
CLE
2 stops18h 21m
American Airlines
Deal found 1/28$548
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:10 am
CLE
-
PTY
1 stop13h 24m
Multiple Airlines
Wed 3/42:55 am
PTY
-
CLE
2 stops18h 42m
Multiple Airlines
Deal found 1/28$549
This KAYAK deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:24 pm
CLE
-
PTY
1 stop16h 46m
Copa Airlines
Thu 3/193:41 pm
PTY
-
CLE
1 stop18h 45m
Copa Airlines
Deal found 1/28$550
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:24 pm
CLE
-
PTY
1 stop7h 38m
United Airlines
Thu 3/193:41 pm
PTY
-
CLE
1 stop18h 45m
United Airlines
Deal found 1/27$551

Find flight deals from Cleveland to Panama

Keep the following information in mind while searching for Cleveland to Panama flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$511
(United Airlines)

One-way from

$243
(Delta)

Popular in

August

Cheapest in

November

Average price

$574
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
Search Deals
From Cleveland Hopkins Intl to Panama
Search Deals
One-way flight from Cleveland Hopkins Intl to Panama
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Cleveland

Fly to

Panama

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

6:00 am-6:37 pm

1 stop13h 37m

Panama City Tocumen Intl

Thu 4/9

3:30 pm-11:25 am

1 stop18h 55m

$511

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 4/1

9:58 am-7:31 pm

1 stop10h 33m

Panama City Tocumen Intl

Mon 4/13

3:30 pm-11:25 am

1 stop18h 55m

$511

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

5:48 pm-12:45 pm

2 stops19h 57m

Panama City Tocumen Intl

Thu 4/9

1:49 pm-12:37 pm

2 stops21h 48m

$515

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 5/3

6:04 am-12:36 pm

1 stop7h 32m

Panama City Tocumen Intl

Fri 5/8

1:49 pm-11:58 pm

1 stop9h 09m

$531

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 3/29

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Mon 3/30

10:55 pm-10:12 am

1 stop10h 17m

$531

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 3/29

6:15 am-2:14 pm

1 stop8h 59m

Panama City Tocumen Intl

Thu 4/2

9:45 am-8:48 pm

1 stop10h 03m

$531

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

6:00 am-6:37 pm

1 stop13h 37m

Panama City Tocumen Intl

Fri 4/10

3:30 pm-11:20 am

1 stop18h 50m

$531

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 3/18

12:22 pm-7:02 pm

1 stop7h 40m

Panama City Tocumen Intl

Sun 3/22

10:55 pm-9:47 am

1 stop9h 52m

$538

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 3/29

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Fri 4/3

9:45 am-8:48 pm

1 stop10h 03m

$550

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/3

4:09 pm-1:40 pm

2 stops21h 31m

$243

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 16 results
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Best time to book a flight from Cleveland to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama

What is the cheapest month to book a flight from Cleveland to Panama?

Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama (average of $384). Flying from Cleveland to Panama in August is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from Cleveland to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,127 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,127 reviews
Delta
7.9
Good
8,127 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,560 reviews
Delta
7.9
Good
8,127 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,215 reviews
Delta
7.9
Good
8,127 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,206 reviews
Delta
7.9
Good
8,127 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cleveland to Panama?

    Cleveland Hopkins Intl (CLE) is the airport you will fly out of if you book a flight from Cleveland to Panama. It is only a 10.1 mi journey to Hopkins Intl (CLE) from Cleveland’s city center.

  • How long is the flight from Cleveland to Panama?

    There are many flights that can get you from Cleveland to Panama in 13h 37m. Fly via United Airlines or American Airlines to get the fastest option. There are 2238 mi between Cleveland and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Cleveland to Panama that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama.

  • Can I find deals for business class flights from Cleveland to Panama?

    Yes. Cheapflights offers flight deals from Cleveland to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama (average of $384). Flying from Cleveland to Panama in August is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cleveland to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Cleveland to Panama

Discover the top 4 airlines that operate flights from Cleveland to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$389Average$570FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$390Average$644FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$489Average$609FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$868Average$1,147FlexibilityNo cancel feeOn-time70%

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