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$232+ Cheap flights from Cleveland (CLE) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
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Cheap flight deals from Cleveland to Panama

Cheapest flights from Cleveland to Panama
Explore the most affordable flight options available from Cleveland to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:58 pmCLE - PTY
1 stop26h 09mUnited Airlines
Wed 12/108:55 amPTY - CLE
1 stop12h 55mUnited Airlines
Deal found 12/6$624
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:02 amCLE - PTY
1 stop8h 43mUnited Airlines
Sat 12/204:41 pmPTY - CLE
1 stop18h 32mUnited Airlines
Deal found 12/6$631
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:03 amCLE - PTY
1 stop11h 04mUnited Airlines
Sat 12/1311:55 pmPTY - CLE
1 stop10h 15mUnited Airlines
Deal found 12/7$632
This American Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:00 amCLE - PTY
1 stop7h 47mAmerican Airlines
Wed 12/104:43 pmPTY - CLE
2 stops20h 51mAmerican Airlines
Deal found 12/6$636
This Delta deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:15 amCLE - PTY
1 stop7h 06mDelta
Sat 12/203:22 pmPTY - CLE
1 stop9h 20mDelta
Deal found 12/7$652
This Copa Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:55 amCLE - PTY
1 stop9h 40mCopa Airlines
Tue 1/68:10 amPTY - CLE
1 stop12h 30mCopa Airlines
Deal found 12/6$702
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amCLE - PTY
2 stops9h 42mAmerican Airlines
Sat 12/204:55 pmPTY - CLE
2 stops17h 50mAmerican Airlines
Deal found 12/7$706
This United Airlines deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:00 amCLE - PTY
1 stop13h 38mUnited Airlines
Wed 12/3111:55 pmPTY - CLE
1 stop9h 52mUnited Airlines
Deal found 12/6$730
This Kiwi.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:43 amCLE - PTY
1 stop8h 36mMultiple Airlines
Wed 12/3111:33 amPTY - CLE
2 stops23h 04mMultiple Airlines
Deal found 12/6$772
This Delta deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:50 amCLE - PTY
1 stop12h 10mDelta
Wed 12/313:22 pmPTY - CLE
1 stop8h 10mDelta
Deal found 12/6$782
This Kiwi.com deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:59 pmCLE - PTY
2 stops30h 01mMultiple Airlines
Tue 12/303:39 pmPTY - CLE
1 stop9h 15mMultiple Airlines
Deal found 12/6$786

Find flight deals from Cleveland to Panama

Keep the following information in mind while searching for Cleveland to Panama flight deals. Data was last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$490
(United Airlines)

One-way from

$232
(Delta)

Popular in

August

Cheapest in

November

Average price

$701
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
Search Deals
From Cleveland Hopkins Intl to Panama
Search Deals
One-way flight from Cleveland Hopkins Intl to Panama
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Cleveland

Fly to

Panama

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 1/26

12:14 pm-8:02 pm

1 stop7h 48m

Panama City Tocumen Intl

Thu 1/29

4:41 pm-11:08 am

1 stop18h 27m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:00 am-2:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Mon 2/2

4:41 pm-11:08 am

1 stop18h 27m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

7:42 pm-2:22 pm

2 stops19h 40m

Panama City Tocumen Intl

Fri 4/10

1:55 pm-11:45 am

2 stops20h 50m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 2/28

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Wed 3/11

3:41 pm-11:26 am

1 stop18h 45m

$510

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 1/31

12:14 pm-8:02 pm

1 stop7h 48m

Panama City Tocumen Intl

Wed 2/4

10:00 am-6:32 pm

1 stop8h 32m

$510

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/3

5:43 pm-1:50 pm

2 stops20h 07m

$232

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/3

6:00 am-1:55 pm

1 stop7h 55m

$232

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 12/14

2:58 pm-5:07 pm

1 stop26h 09m

$291

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 12/14

5:40 pm-1:47 pm

2 stops20h 07m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Best time to book a flight from Cleveland to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama

What is the cheapest month to book a flight from Cleveland to Panama?

Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama (average of $384). Flying from Cleveland to Panama in August is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to PA?

Find hourly flight availability from Cleveland to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

It’s typically best to fly out from Cleveland to Panama in the afternoon. Doing so could potentially save you 42% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 8, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Cleveland to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,013 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,013 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,076 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,042 reviews
Delta
7.9
Good
8,013 reviews

Crew

8.5

Comfort

7.9

Overall

7.9

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Cleveland to Panama?

    Cleveland Hopkins Intl (CLE) is the airport you will fly out of if you book a flight from Cleveland to Panama. It is only a 10.1 mi journey to Hopkins Intl (CLE) from Cleveland’s city center.

  • How long is the flight from Cleveland to Panama?

    There are many flights that can get you from Cleveland to Panama in 7h 48m. Fly via United Airlines to get the fastest option. There are 2238 mi between Cleveland and Panama.

  • Can I find deals for flights from Cleveland to Panama that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama.

  • Can I find deals for business class flights from Cleveland to Panama?

    Yes. Cheapflights offers flight deals from Cleveland to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama?

    Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama (average of $384). Flying from Cleveland to Panama in August is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cleveland to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Cleveland to Panama

Discover the top 3 airlines that operate flights from Cleveland to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$389Average$570FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$390Average$593FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$591FlexibilityNo cancel feeOn-time69%

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