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$167+ Cheap flights from Chicago (CHI) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Chicago to Panama

Keep the following information in mind while searching for Chicago to Panama flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$465
(Copa Airlines)

One-way from

$167
(Flightnetwork)

Popular in

December

Cheapest in

November

Average price

$517

Good round-trip deal

$465 or less

Good one-way deal

$200 or less
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
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From Chicago (CHI) to Panama
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One-way flight from Chicago (CHI) to Panama
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Highest demand for flights based on searches. 8% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Price to beat on a round-trip flight from Chicago (CHI) to Panama.
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Price to beat on a one-way flight from Chicago (CHI) to Panama.
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Find flight deals from Chicago to Panama

Cheapest flights from Chicago to Panama
Explore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/97:54 amORD - PTY
Nonstop5h 28mCopa Airlines
Mon 6/166:45 pmPTY - ORD
Nonstop5h 49mCopa Airlines
Deal found 4/30$465
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/301:35 pmORD - PTY
1 stop9h 45mAvianca
Sun 12/76:30 pmPTY - ORD
1 stop18h 45mAvianca
Deal found 4/30$467
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/302:35 pmORD - PTY
1 stop9h 35mMultiple Airlines
Sun 6/19:21 pmPTY - ORD
2 stops35h 29mMultiple Airlines
Deal found 4/30$470
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:00 amMDW - PTY
1 stop6h 48mDelta
Sat 5/318:00 amPTY - MDW
1 stop13h 13mDelta
Deal found 4/30$479
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:59 pmORD - PTY
1 stop16h 49mDelta
Mon 6/22:13 pmPTY - ORD
1 stop9h 45mDelta
Deal found 4/30$479
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/239:40 pmORD - PTY
1 stop20h 57mUnited Airlines
Thu 5/2910:00 amPTY - ORD
1 stop13h 12mUnited Airlines
Deal found 4/30$489
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:20 amMDW - PTY
1 stop13h 13mMultiple Airlines
Tue 6/39:25 amPTY - MDW
1 stop13h 19mMultiple Airlines
Deal found 4/30$571
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/118:37 pmORD - PTY
2 stops15h 48mAmerican Airlines
Mon 10/131:50 pmPTY - ORD
1 stop8h 44mAmerican Airlines
Deal found 4/30$571
This Copa Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/143:07 pmORD - DAV
1 stop17h 53mCopa Airlines
Sat 6/219:44 amDAV - ORD
1 stop14h 50mCopa Airlines
Deal found 4/30$943
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/149:40 pmORD - DAV
2 stops19h 48mUnited Airlines
Sat 6/219:44 amDAV - ORD
2 stops35h 46mUnited Airlines
Deal found 4/30$1,100

Cheapflights Fare Finder

Customize your flight search to find flights from Chicago to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Chicago to Panama that are best for you.

Fly from

Chicago

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 6/9

7:54 am-1:22 pm

Nonstop5h 28m

Panama City Tocumen Intl

Mon 6/16

6:45 pm-12:34 am

Nonstop5h 49m

$465

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 6/15

3:45 pm-10:25 am

2 stops18h 40m

Panama City Tocumen Intl

Fri 6/20

3:40 pm-1:15 pm

2 stops21h 35m

$469

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 5/30

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Sun 6/1

9:21 pm-8:50 am

2 stops35h 29m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 5/28

6:00 am-12:48 pm

1 stop6h 48m

Panama City Tocumen Intl

Sat 5/31

8:00 am-9:13 pm

1 stop13h 13m

$479

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 5/28

5:30 am-12:48 pm

1 stop7h 18m

Panama City Tocumen Intl

Tue 6/3

2:13 pm-8:29 am

1 stop18h 16m

$479

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 5/23

9:40 pm-6:37 pm

1 stop20h 57m

Panama City Tocumen Intl

Wed 5/28

10:00 am-12:13 am

1 stop14h 13m

$489

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 10/11

8:37 pm-12:25 pm

2 stops15h 48m

Panama City Tocumen Intl

Mon 10/13

1:50 pm-10:34 pm

1 stop8h 44m

$571

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 6/1

6:20 am-7:33 pm

1 stop13h 13m

Panama City Tocumen Intl

Tue 6/3

9:25 am-10:44 pm

1 stop13h 19m

$571

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Sat 6/14

3:07 pm-9:00 am

1 stop17h 53m

David Enrique Malek

Sat 6/21

9:44 am-12:34 am

1 stop14h 50m

$943

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Sat 6/14

9:40 pm-5:28 pm

2 stops19h 48m

David Enrique Malek

Sat 6/21

9:44 am-9:30 pm

2 stops35h 46m

$1,100

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 19 results
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Best time to book a flight from Chicago to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Panama

What is the cheapest month to book a flight from Chicago to Panama?

Currently, October is the cheapest month in which you can book a flight from Chicago to Panama (average of $478). Flying from Chicago to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to PA?

Find hourly flight availability from Chicago to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

One of the essential ways to save on airfare from Chicago to Panama is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 6% on airfare.

What is the cheapest day to fly from Chicago to Panama?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama. Price data was last updated on June 30, 2024.

Travelers seeking maximum savings on their Chicago to Panama flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated May 1, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines and Aeromexico from Chicago to Panama by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,415 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aeromexico
7.5
Good
1,698 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Turkish Airlines
7.3
Good
3,791 reviews
Delta
8.0
Very good
7,934 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago to Panama one-way?

    The cheapest airline one-way is Avianca, with whom users have recently found tickets for as low as $167. However, be on the lookout for offers from United Airlines and Copa Airlines, as they are both options that can get you from Chicago to Panama for a low price.

  • What are the most popular routes from Chicago to Panama?

    The most popular route from Chicago to Panama is Chicago O'Hare Intl - Panama City Tocumen Intl. You may also consider Chicago Midway - Panama City Tocumen Intl or Chicago O'Hare Intl - David Enrique Malek.

  • What are the most reliable airlines from Chicago to Panama?

    The top 3 most reliable airlines when flying from Chicago to Panama are Copa Airlines (94%), United Airlines (94%) and EVA Air (93%).

  • What are the cheapest flights from Chicago to Panama?

    While on average a flight from Chicago to Panama is generally $855, our data shows the cheapest flight currently is $130. When looking at the most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), you can expect to pay $386 for that flight.

  • Can I find deals for flights from Chicago to Panama that include hotel bookings?

    Yes. In addition to deals on Chicago to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Panama.

  • Can I find deals for business class flights from Chicago to Panama?

    Yes. Cheapflights offers flight deals from Chicago to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Panama?

    Currently, October is the cheapest month in which you can book a flight from Chicago to Panama (average of $478). Flying from Chicago to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to Panama

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Panama City flights
O'Hare Intl to San José flights
O'Hare Intl to Guatemala City flights
O'Hare Intl to Liberia flights
O'Hare Intl to San Salvador flights
Midway to Guatemala City flights
O'Hare Intl to Philip S.W.Goldson flights
Midway to San José flights
St. Louis to San José flights
St. Louis to Philip S.W.Goldson flights
O'Hare Intl to Coxen Hole flights
O'Hare Intl to Managua flights
Midway to Panama City flights
O'Hare Intl to San Pedro Sula flights
St. Louis to Liberia flights
Midway to Liberia flights
Midway to Philip S.W.Goldson flights
St. Louis to Panama City flights
St. Louis to Guatemala City flights
Midway to San Pedro Sula flights
St. Louis to San Pedro Sula flights
Evansville to Panama City flights
Midway to San Salvador flights
Bloomington to San José flights
St. Louis to Coxen Hole flights
O'Hare Intl to David flights
Moline to Guatemala City flights
Midway to Managua flights
Moline to San José flights
Midway to Coxen Hole flights
Moline to Philip S.W.Goldson flights
Moline to Liberia flights
Midway to Tegucigalpa flights
St. Louis to Managua flights
St. Louis to Tegucigalpa flights
Peoria to San Salvador flights
O'Hare Intl to Tegucigalpa flights
Springfield to Liberia flights
Moline to San Salvador flights
Bloomington to Philip S.W.Goldson flights

Top 5 airlines flying from Chicago to Panama

Discover the top 5 airlines that operate flights from Chicago to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$339Average$450FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$464Average$715FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$478Average$632FlexibilityNo cancel feeOn-time71%
DeltaCheapest$478Average$646FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$478Average$636FlexibilityNo cancel feeOn-time69%

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