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$104+ Cheap flights from Chicago (CHI) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Mar 3 — Mar 101
Tue 3/3
Tue 3/10
1 adult, Economy
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Cheap flight deals from Chicago to Panama

Cheapest flights from Chicago to Panama
Explore the most affordable flight options available from Chicago to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 1, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:57 pm
ORD
-
PTY
2 stops12h 53m
Multiple Airlines
Thu 2/129:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 1/31$412
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:36 pm
ORD
-
PTY
3 stops32h 04m
Multiple Airlines
Tue 3/249:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 1/31$418
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:57 pm
ORD
-
PTY
2 stops12h 53m
Multiple Airlines
Wed 2/119:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 1/31$420
This Avianca deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:20 pm
ORD
-
PTY
1 stop14h 40m
Avianca
Thu 4/210:10 am
PTY
-
ORD
1 stop11h 10m
Avianca
Deal found 1/31$426
This Priceline deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/610:20 pm
ORD
-
PTY
1 stop14h 40m
Avianca
Mon 2/99:45 am
PTY
-
ORD
1 stop11h 35m
Avianca
Deal found 1/31$427
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1710:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Fri 2/205:50 pm
PTY
-
ORD
2 stops16h 49m
Multiple Airlines
Deal found 1/31$428
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:16 pm
ORD
-
PTY
3 stops27h 24m
Multiple Airlines
Sun 3/85:50 pm
PTY
-
ORD
3 stops29h 57m
Multiple Airlines
Deal found 1/31$429
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/149:18 am
ORD
-
PTY
2 stops14h 42m
Multiple Airlines
Thu 2/199:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 1/31$434
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:55 am
ORD
-
PTY
1 stop8h 25m
Multiple Airlines
Thu 3/199:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 1/31$442
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:15 am
MDW
-
PTY
1 stop8h 51m
Multiple Airlines
Sun 3/85:50 pm
PTY
-
MDW
2 stops19h 51m
Multiple Airlines
Deal found 1/31$516
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
MDW
-
PTY
1 stop14h 34m
Multiple Airlines
Tue 3/2410:26 am
PTY
-
MDW
1 stop10h 28m
Multiple Airlines
Deal found 1/31$528
This Kiwi.com deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:15 am
MDW
-
PTY
1 stop8h 51m
Multiple Airlines
Mon 3/99:34 am
PTY
-
MDW
2 stops11h 19m
Multiple Airlines
Deal found 1/30$563

Find flight deals from Chicago to Panama

Keep the following information in mind while searching for Chicago to Panama flight deals. Data was last updated February 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$412
(Kiwi.com)

One-way from

$104
(Super.com)

Popular in

May

Cheapest in

July

Average price

$572

Good round-trip deal

$355 or less

Good one-way deal

$180 or less
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
Search Deals
From Chicago (CHI) to Panama
Search Deals
One-way flight from Chicago (CHI) to Panama
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to Panama.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to Panama.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
Use the filters below to find and compare flights from Chicago to Panama that are best for you.

Fly from

Chicago

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 3/1

6:51 pm-4:55 pm

2 stops21h 04m

Panama City Tocumen Intl

Sun 3/8

2:55 pm-11:47 pm

3 stops32h 52m

$435

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 3/12

10:55 am-10:30 am

3 stops23h 35m

Panama City Tocumen Intl

Mon 3/16

9:45 am-9:20 pm

1 stop11h 35m

$453

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 3/1

6:15 am-4:06 pm

1 stop8h 51m

Panama City Tocumen Intl

Sun 3/8

5:50 pm-1:41 pm

2 stops19h 51m

$516

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 2/21

10:20 pm-2:00 pm

1 stop14h 40m

Panama City Tocumen Intl

Sat 2/28

7:50 pm-9:34 am

2 stops14h 44m

$528

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 7/26

7:30 am-4:12 pm

1 stop8h 42m

Panama City Tocumen Intl

Sat 8/1

7:55 am-9:31 pm

1 stop13h 36m

$563

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 5/29

11:20 pm-5:00 pm

1 stop17h 40m

Panama City Tocumen Intl

Tue 6/30

5:30 am-3:55 pm

1 stop10h 25m

$564

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 4/10

8:06 am-1:22 pm

Nonstop5h 16m

Panama City Tocumen Intl

Fri 4/24

7:25 pm-1:13 am

Nonstop5h 48m

$565

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 3/27

8:34 am-2:00 pm

Nonstop5h 26m

Panama City Tocumen Intl

Fri 4/3

7:25 pm-1:13 am

Nonstop5h 48m

$565

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 3/31

5:48 am-6:37 pm

1 stop12h 49m

Panama City Tocumen Intl

Wed 4/1

10:55 pm-9:13 am

1 stop10h 18m

$580

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 3/30

5:48 am-2:14 pm

1 stop8h 26m

Panama City Tocumen Intl

Wed 4/1

9:45 am-8:17 pm

1 stop10h 32m

$580

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 47 results
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Best time to book a flight from Chicago to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Panama

What is the cheapest month to book a flight from Chicago to Panama?

Currently, April is the cheapest month in which you can book a flight from Chicago to Panama (average of $264). Flying from Chicago to Panama in February is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to PA?

Find hourly flight availability from Chicago to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 1, 2026.

One of the essential ways to save on airfare from Chicago to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 13% on airfare.

What is the cheapest day to fly from Chicago to Panama?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Chicago to Panama flight should consider departing on Monday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Panama

Explore weekly flight availability from Chicago to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 1, 2026.

The most flights from CHI to PA0 are scheduled on a Thursday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (3 on average).

How often are flights from Chicago to Panama delayed?

About 10% of weekly flights between Chicago and Panama have experienced delays in the past year, with the average delay time being 128 minutes.

What is the most punctual flight time for Chicago to Panama flights?

Historically, flights departing in the evening are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Chicago to Panama flights?

Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 9% of flights being delayed.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 1, 2026.
See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Chicago to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,130 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,130 reviews
Delta
7.9
Good
8,130 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,561 reviews
Delta
7.9
Good
8,130 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,219 reviews
Delta
7.9
Good
8,130 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,211 reviews
Delta
7.9
Good
8,130 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Avianca
6.6
Okay
2,493 reviews
Delta
7.9
Good
8,130 reviews

Entertainment

7.8

Overall

7.9

Boarding

8.1

Food

7.2

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Chicago to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to Panama?

    For as low as $594, United Airlines can have you in Panama from Chicago in 8h 24m. Airlines will cover a distance of 2343 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Chicago to Panama one-way?

    The cheapest airline one-way is Avianca, with whom users have recently found tickets for as low as $102. However, be on the lookout for offers from Copa Airlines and American Airlines, as they are both options that can get you from Chicago to Panama for a low price.

  • What are the most popular routes from Chicago to Panama?

    The most popular route from Chicago to Panama is Chicago O'Hare Intl - Panama City Tocumen Intl. You may also consider Chicago Midway - Panama City Tocumen Intl or Chicago O'Hare Intl - David Enrique Malek.

  • What are the most reliable airlines from Chicago to Panama?

    The top 3 most reliable airlines when flying from Chicago to Panama are United Airlines (80%), Copa Airlines (80%) and EVA Air (78%).

  • What are the cheapest flights from Chicago to Panama?

    While on average a flight from Chicago to Panama is generally $559, our data shows the cheapest flight currently is $153. When looking at the most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl), you can expect to pay $336 for that flight.

  • Can I find deals for flights from Chicago to Panama that include hotel bookings?

    Yes. In addition to deals on Chicago to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Panama.

  • Can I find deals for business class flights from Chicago to Panama?

    Yes. Cheapflights offers flight deals from Chicago to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Panama?

    Currently, April is the cheapest month in which you can book a flight from Chicago to Panama (average of $264). Flying from Chicago to Panama in February is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to Panama

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to San José flights
O'Hare Intl to Panama City flights
O'Hare Intl to Liberia flights
O'Hare Intl to Guatemala City flights
Midway to San José flights
O'Hare Intl to Philip S.W.Goldson flights
Midway to Guatemala City flights
Midway to Panama City flights
O'Hare Intl to San Salvador flights
O'Hare Intl to Coxen Hole flights
Midway to Philip S.W.Goldson flights
O'Hare Intl to Managua flights
St. Louis to San José flights
Midway to Liberia flights
St. Louis to Panama City flights
O'Hare Intl to San Pedro Sula flights
St. Louis to Philip S.W.Goldson flights
St. Louis to Liberia flights
Midway to San Salvador flights
St. Louis to Guatemala City flights
Midway to San Pedro Sula flights
St. Louis to Coxen Hole flights
O'Hare Intl to David flights
Midway to Coxen Hole flights
Evansville to Panama City flights
Peoria to San Salvador flights
Midway to Managua flights
Moline to Philip S.W.Goldson flights
Bloomington to San José flights
St. Louis to San Pedro Sula flights
St. Louis to Managua flights
Moline to San José flights
Moline to Liberia flights
Moline to Guatemala City flights
Midway to Tegucigalpa flights
Moline to San Salvador flights
Bloomington to Philip S.W.Goldson flights
St. Louis to Tegucigalpa flights
Springfield to Liberia flights
O'Hare Intl to Tegucigalpa flights

Top 5 airlines flying from Chicago to Panama

Discover the top 5 airlines that operate flights from Chicago to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$251Average$476FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$462Average$644FlexibilityNo cancel feeOn-time70%
DeltaCheapest$479Average$697FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$479Average$653FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$563Average$708FlexibilityNo cancel feeOn-time71%

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