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$437+ Cheap flights from Frankfurt (FRA) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — PTY
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheapflights Tip: The best prices from Frankfurt am Main to Panama City Tocumen Intl are usually found in May or June, booked 63 days in advance, depart on a Monday or Wednesday and return on a Wednesday

Cheap flight deals from Frankfurt to Panama City

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Air Europa deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:45 am
FRA
-
PTY
1 stop15h 00m
Air Europa
Tue 3/179:30 pm
PTY
-
FRA
1 stop30h 15m
Air Europa
Deal found 1/25$718
This Air Europa deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:05 pm
FRA
-
PTY
1 stop30h 40m
Air Europa
Tue 3/318:25 pm
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 1/25$720
This Air Europa deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:55 am
FRA
-
PTY
1 stop14h 45m
Air Europa
Tue 5/268:25 pm
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 1/27$722
This Air Europa deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:55 am
FRA
-
PTY
1 stop14h 45m
Air Europa
Tue 6/308:25 pm
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 1/27$724
This Air Europa deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:45 am
FRA
-
PTY
1 stop15h 00m
Air Europa
Mon 3/239:30 pm
PTY
-
FRA
1 stop30h 15m
Air Europa
Deal found 1/26$728
This Air Europa deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:45 am
FRA
-
PTY
1 stop15h 00m
Air Europa
Sun 3/89:30 pm
PTY
-
FRA
1 stop30h 15m
Air Europa
Deal found 1/27$730
This Air Europa deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:05 pm
FRA
-
PTY
1 stop30h 40m
Air Europa
Wed 4/18:25 pm
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 1/27$733
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:15 am
FRA
-
PTY
2 stops16h 30m
Multiple Airlines
Sun 5/179:55 pm
PTY
-
FRA
1 stop33h 25m
Multiple Airlines
Deal found 1/25$734
This Air Europa deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:10 pm
FRA
-
PTY
1 stop30h 30m
Air Europa
Sat 6/278:25 pm
PTY
-
FRA
1 stop14h 25m
Air Europa
Deal found 1/27$735
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:35 am
FRA
-
PTY
2 stops19h 56m
United Airlines
Wed 4/299:45 am
PTY
-
FRA
2 stops19h 25m
United Airlines
Deal found 1/26$737
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:45 am
FRA
-
PTY
2 stops18h 46m
United Airlines
Sun 5/39:45 am
PTY
-
FRA
2 stops19h 25m
United Airlines
Deal found 1/27$738
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:35 am
FRA
-
PTY
2 stops19h 56m
United Airlines
Mon 4/279:45 am
PTY
-
FRA
2 stops25h 20m
United Airlines
Deal found 1/25$739

Find flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$718
(Air Europa)

One-way from

$437
(KLM)

Popular in

July

Cheapest in

May

Average price

$831
Provider with most accurate pricing for Frankfurt am Main-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Frankfurt am Main-Panama City Tocumen Intl flights.
Search Deals
From Frankfurt am Main to Panama City Tocumen Intl
Search Deals
One-way flight from Frankfurt am Main to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Frankfurt

Fly to

Panama City

Route

Depart

Return

Price

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 5/6

10:55 am-6:40 pm

1 stop14h 45m

Panama City Tocumen Intl

Tue 5/26

8:25 pm-5:50 pm

1 stop14h 25m

$722

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Sat 4/25

11:25 am-4:04 am

2 stops23h 39m

Panama City Tocumen Intl

Mon 5/4

9:45 am-9:10 am

1 stop16h 25m

$738

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Thu 5/21

7:45 am-7:31 pm

2 stops18h 46m

Panama City Tocumen Intl

Mon 5/25

9:45 am-9:10 am

1 stop16h 25m

$738

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 3/11

1:50 pm-1:45 pm

1 stop29h 55m

Panama City Tocumen Intl

Wed 3/18

3:41 pm-9:00 am

1 stop35h 19m

$741

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 3/6

8:40 am-5:10 am

2 stops26h 30m

Panama City Tocumen Intl

Mon 3/16

7:55 am-11:40 am

1 stop21h 45m

$745

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Tue 3/31

1:55 pm-2:14 pm

1 stop31h 19m

Panama City Tocumen Intl

Sat 4/18

10:00 am-11:15 am

1 stop18h 15m

$745

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Mon 2/9

1:50 pm-5:07 pm

1 stop33h 17m

Panama City Tocumen Intl

Sun 2/22

4:41 pm-11:40 am

1 stop36h 59m

$745

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 4/3

1:55 pm-2:14 pm

1 stop31h 19m

Panama City Tocumen Intl

Sun 4/12

3:30 pm-11:15 am

1 stop36h 45m

$746

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Fri 4/3

1:55 pm-2:14 pm

1 stop31h 19m

Panama City Tocumen Intl

Fri 4/24

10:00 am-12:10 pm

2 stops19h 10m

$746

Frankfurt am MainPanama City

FRA - PTY

FRAPTY

Frankfurt am Main

Wed 3/18

10:15 am-8:10 pm

2 stops15h 55m

$437

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 15 results
1
2
  • Most accurate provider: When it comes to deals on Frankfurt am Main Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Frankfurt am Main Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Frankfurt am Main Airport-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Frankfurt am Main Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Frankfurt am Main Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

How far ahead should I book a flight from Frankfurt am Main Airport to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Frankfurt to Panama City. Price data was last updated on January 23, 2026.

The best time to book flights from Frankfurt am Main Airport to Panama City is 63 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

Currently, June is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of $393). Flying from Frankfurt am Main Airport to Panama City in July is currently the most expensive (average of $658). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Frankfurt am Main Airport to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 27, 2026.
Read through reviews of airlines operating flights from Frankfurt am Main Airport to Panama City, such as United Airlines and Condor. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,206 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,206 reviews
United Airlines
7.4
Good
9,206 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
Condor
6.4
Okay
399 reviews
United Airlines
7.4
Good
9,206 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    If you book a flight to Panama City from Frankfurt am Main, you will be flying to Tocumen Intl, which is the city’s only airport. Panama City Tocumen Intl (PTY) is located 11.4 mi from the center of Panama City. There are 0 flights from Frankfurt am Main to Tocumen Intl per day from 2 different airlines.

  • How long is the flight from Frankfurt am Main Airport to Panama City?

    Departing from Frankfurt am Main Airport to Panama City will take you 18h 46m. The distance from Frankfurt am Main Airport to Panama City is about 5644 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Frankfurt am Main Airport to Panama City round-trip?

    Our cheapest airline available from Frankfurt am Main Airport to Panama City is Condor. Our recent data shows that you can find tickets from as low as $526 on this airline. An additional option worth looking into is United Airlines, starting at $638. These flights start at 29% lower than the current average price 3 months from now.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City?

    Currently, June is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City (average of $393). Flying from Frankfurt am Main Airport to Panama City in July is currently the most expensive (average of $658). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Frankfurt to Panama City

Discover the top 2 airlines that operate flights from Frankfurt to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
CondorCheapest$526Average$910FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$638Average$739FlexibilityNo cancel feeOn-time69%

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