HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Palermo

$388+ Cheap flights from South Carolina to Palermo (PMO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PMO
Sep 6 — Sep 131
Sat 9/6
Sat 9/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Palermo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Palermo

Keep the following information in mind while searching for South Carolina to Palermo flight deals. Data was last updated September 1, 2025.

Round-trip from

$777
(KAYAK)

One-way from

$388
(Trip.com)
From South Carolina to Palermo Punta Raisi
Search Deals
One-way flight from South Carolina to Palermo Punta Raisi
Search Deals

Find flight deals from South Carolina to Palermo

Cheapest flights from South Carolina to Palermo
Explore the most affordable flight options available from South Carolina to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2025.

This Booking.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:30 amCLT - PMO
2 stops19h 35mMultiple Airlines
Mon 12/157:15 pmPMO - CLT
2 stops27h 40mMultiple Airlines
Deal found 8/30$753
This KAYAK deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:50 pmCLT - PMO
2 stops17h 35mSWISS
Sun 11/162:45 pmPMO - CLT
2 stops56h 10mSWISS
Deal found 8/30$777
This Ovago deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:50 pmCLT - PMO
2 stops17h 35mMultiple Airlines
Sun 11/166:25 pmPMO - CLT
1 stop28h 30mMultiple Airlines
Deal found 8/30$800
This Mytrip deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:10 amCLT - PMO
2 stops32h 00mMultiple Airlines
Sat 9/66:30 amPMO - CLT
3 stops39h 02mMultiple Airlines
Deal found 8/31$1,143
This Air Canada deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/910:00 amCLT - PMO
3 stops19h 40mAir Canada
Sun 11/1610:00 amPMO - CLT
3 stops36h 17mAir Canada
Deal found 8/30$1,186
This Gurufare deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:50 pmCLT - PMO
2 stops34h 50mLufthansa
Sat 12/2712:10 pmPMO - CLT
1 stop34h 45mLufthansa
Deal found 8/31$1,331

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 1, 2025.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

South Carolina

Fly to

Palermo

Route

Depart

Return

Price

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/9

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sun 11/16

2:45 pm-4:55 pm

2 stops56h 10m

$777

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/9

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sun 11/16

6:25 pm-4:55 pm

1 stop28h 30m

$800

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Thu 9/4

9:10 am-11:10 pm

2 stops32h 00m

Palermo Punta Raisi

Sat 9/6

6:30 am-3:32 pm

3 stops39h 02m

$1,143

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/9

10:00 am-11:40 am

3 stops19h 40m

Palermo Punta Raisi

Sun 11/16

10:00 am-4:17 pm

3 stops36h 17m

$1,186

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Wed 10/29

7:44 pm-11:30 am

2 stops34h 46m

Palermo Punta Raisi

Sun 11/9

6:25 pm-4:55 pm

1 stop28h 30m

$4,275

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/30

6:50 pm-9:35 pm

2 stops20h 45m

$388

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/30

1:56 pm-11:40 am

2 stops15h 44m

$1,072

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/30

9:30 am-11:40 am

3 stops20h 10m

$1,095

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/30

6:50 pm-11:00 pm

2 stops22h 10m

$2,926

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/30

Best time to book a flight from South Carolina to Palermo

Have a flexible travel schedule? Discover the best time to fly to Palermo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Palermo

What is the cheapest month to book a flight from South Carolina to Palermo?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Palermo (average of $758). Flying from South Carolina to Palermo in June is currently the most expensive (average of $1,196). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to PMO?

Find hourly flight availability from South Carolina to Palermo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Palermo as you normally would.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Palermo from South Carolina?

    Palermo Punta Raisi (PMO), located 15.2 mi from the city center, is the airport you fly into when you book flights from South Carolina to Palermo.

  • How long is the flight from South Carolina to Palermo?

    For as low as $777, SWISS can have you in Palermo from South Carolina in 17h 35m. Airlines will cover a distance of 4962 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Palermo one-way?

    The cheapest airlines for a one-way flight from South Carolina to Palermo are Brussels Airlines ($1,072), Air Canada ($1,095), and Lufthansa ($2,926).

  • What are the most popular routes from South Carolina to Palermo?

    The most popular route from South Carolina to Palermo is Charlotte Douglas - Palermo Punta Raisi. You may also consider Myrtle Beach Intl - Palermo Punta Raisi or Columbia Metropolitan - Palermo Punta Raisi.

  • Can I find deals for flights from South Carolina to Palermo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Palermo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Palermo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Palermo.

  • Can I find deals for business class flights from South Carolina to Palermo?

    Yes. Cheapflights offers flight deals from South Carolina to Palermo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Palermo?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Palermo (average of $758). Flying from South Carolina to Palermo in June is currently the most expensive (average of $1,196). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Agrigento
Cefalù

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Palermo

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Catania flights
John F Kennedy Intl to Palermo flights
Newark to Palermo flights
Newark to Catania flights
LaGuardia to Catania flights
LaGuardia to Palermo flights
Boston to Palermo flights
Boston to Catania flights
O'Hare Intl to Palermo flights
Dulles Intl to Palermo flights
San Francisco to Palermo flights
Miami to Palermo flights
San Francisco to Catania flights
Miami to Catania flights
Reagan-National to Palermo flights
Los Angeles to Catania flights
O'Hare Intl to Catania flights
Los Angeles to Palermo flights
Dulles Intl to Catania flights
Seattle to Palermo flights
Seattle to Catania flights
John F Kennedy Intl to Lamezia Terme flights
Baltimore to Palermo flights
Reagan-National to Catania flights
Newark to Lamezia Terme flights
San Diego to Palermo flights
San Diego to Catania flights
Baltimore to Catania flights
Tampa to Palermo flights
Philadelphia to Catania flights
Rochester to Palermo flights
Charlotte to Catania flights
John F Kennedy Intl to Reggio Calabria flights
Orlando to Catania flights
Detroit to Palermo flights
Atlanta to Catania flights
Sky Harbor Intl to Palermo flights
LaGuardia to Lamezia Terme flights
Fort Lauderdale to Catania flights
Denver to Catania flights
Philadelphia to Palermo flights
West Palm Beach to Catania flights
Tampa to Catania flights
Cleveland to Palermo flights
Newark to Reggio Calabria flights
Cleveland to Catania flights
Atlanta to Palermo flights
Dallas/Fort Worth to Catania flights
Boston to Lamezia Terme flights
Charleston to Catania flights

Top airline flying from South Carolina to Palermo

Discover the top airline that operate flights from South Carolina to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$861Average$1,468FlexibilityNo cancel feeOn-time76%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.