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Palermo

$721+ Cheap flights from South Carolina to Palermo (PMO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PMO
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Find flight deals from South Carolina to Palermo

Cheapest flights from South Carolina to Palermo
Explore the most affordable flight options available from South Carolina to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This KAYAK deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:50 pmCLT - PMO
2 stops17h 35mSWISS
Sun 11/162:45 pmPMO - CLT
2 stops56h 10mSWISS
Deal found 10/20$721
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:50 pmCLT - PMO
2 stops17h 35mMultiple Airlines
Sun 11/166:25 pmPMO - CLT
1 stop28h 30mMultiple Airlines
Deal found 10/20$763
This KLM deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:56 pmCAE - PMO
2 stops23h 24mKLM
Tue 11/182:25 pmPMO - CAE
2 stops34h 34mKLM
Deal found 10/20$767
This Air Canada deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/910:00 amCLT - PMO
3 stops19h 40mAir Canada
Sun 11/1610:00 amPMO - CLT
3 stops36h 17mAir Canada
Deal found 10/20$1,594
This KAYAK deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:54 pmCLT - PMO
2 stops14h 31mLufthansa
Sun 1/116:25 pmPMO - CLT
1 stop28h 30mLufthansa
Deal found 10/21$1,601

Cheap flight deals from South Carolina to Palermo

Keep the following information in mind while searching for South Carolina to Palermo flight deals. Data was last updated October 22, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$721
(KAYAK)
Provider with most accurate pricing for Myrtle Beach Intl-Palermo Punta Raisi flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Palermo Punta Raisi flights.
Search Deals
From South Carolina to Palermo Punta Raisi
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

South Carolina

Fly to

Palermo

Route

Depart

Return

Price

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/9

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sun 11/16

2:45 pm-4:55 pm

2 stops56h 10m

$721

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Wed 4/1

10:40 am-5:15 pm

2 stops24h 35m

Palermo Punta Raisi

Sun 4/5

11:50 am-4:45 pm

1 stop34h 55m

$754

ColumbiaPalermo

CAE - PMO

CAEPMO

Columbia Metropolitan

Fri 11/14

11:03 am-6:20 pm

2 stops25h 17m

Palermo Punta Raisi

Tue 11/18

10:00 am-6:59 pm

2 stops38h 59m

$767

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/15

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/21

12:10 pm-4:55 pm

1 stop34h 45m

$839

Myrtle BeachPalermo

MYR - PMO

MYRPMO

Myrtle Beach Intl

Sat 3/28

2:15 pm-3:45 pm

2 stops20h 30m

Palermo Punta Raisi

Wed 4/1

6:50 pm-11:35 pm

2 stops34h 45m

$1,299

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 11/9

8:52 am-9:35 pm

3 stops30h 43m

Palermo Punta Raisi

Sun 11/16

4:15 pm-4:55 pm

3 stops30h 40m

$1,562

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Best time to book a flight from South Carolina to Palermo

Have a flexible travel schedule? Discover the best time to fly to Palermo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Palermo

What is the cheapest time of day to fly from SC to PMO?

Find hourly flight availability from South Carolina to Palermo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

When flying from South Carolina to Palermo, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 41% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Palermo from South Carolina?

    Palermo Punta Raisi (PMO), located 15.2 mi from the city center, is the airport you fly into when you book flights from South Carolina to Palermo.

  • How long is the flight from South Carolina to Palermo?

    For as low as $721, SWISS can have you in Palermo from South Carolina in 17h 35m. Airlines will cover a distance of 4962 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Palermo?

    The most popular route from South Carolina to Palermo is Charlotte Douglas - Palermo Punta Raisi. You may also consider Columbia Metropolitan - Palermo Punta Raisi or Myrtle Beach Intl - Palermo Punta Raisi.

  • Can I find deals for flights from South Carolina to Palermo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Palermo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Palermo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Palermo.

  • Can I find deals for business class flights from South Carolina to Palermo?

    Yes. Cheapflights offers flight deals from South Carolina to Palermo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Agrigento
Cefalù

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Top airline flying from South Carolina to Palermo

Discover the top airline that operate flights from South Carolina to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$861Average$1,468FlexibilityNo cancel feeOn-time76%

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