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Palermo

$480+ Cheap flights from South Carolina to Palermo (PMO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PMO
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from South Carolina to Palermo

Cheapest flights from South Carolina to Palermo
Explore the most affordable flight options available from South Carolina to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Gurufare deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:54 pmCLT - PMO
2 stops14h 31mLufthansa
Sun 1/116:10 amPMO - CLT
2 stops16h 45mLufthansa
Deal found 12/13$2,234
This Arangrant deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arangrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:50 pmCLT - PMO
1 stop16h 35mLufthansa
Fri 12/1912:10 pmPMO - CLT
1 stop34h 45mLufthansa
Deal found 12/12$8,814
This Arangrant deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arangrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:47 pmCLT - PMO
2 stops17h 43mMultiple Airlines
Fri 12/1912:10 pmPMO - CLT
1 stop34h 45mMultiple Airlines
Deal found 12/12$9,027
This AranGrant deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AranGrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:50 pmCLT - PMO
2 stops41h 35mSWISS
Fri 12/197:55 pmPMO - CLT
2 stops31h 25mSWISS
Deal found 12/12$9,435
This Air Canada deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:49 pmCLT - PMO
3 stops36h 41mAir Canada
Fri 12/196:10 amPMO - CLT
3 stops40h 07mAir Canada
Deal found 12/12$11,489

Find flight deals from South Carolina to Palermo

Keep the following information in mind while searching for South Carolina to Palermo flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$681
(Cheapflightsfares)

One-way from

$480
(FlightHub)
Provider with most accurate pricing for Myrtle Beach Intl-Palermo Punta Raisi flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Palermo Punta Raisi flights.
Search Deals
From South Carolina to Palermo Punta Raisi
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One-way flight from South Carolina to Palermo Punta Raisi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from South Carolina to Palermo that are best for you.

Fly from

South Carolina

Fly to

Palermo

Route

Depart

Return

Price

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Tue 1/20

2:54 pm-1:40 pm

2 stops16h 46m

Palermo Punta Raisi

Tue 1/27

3:15 pm-6:59 pm

2 stops33h 44m

$709

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Tue 1/20

2:54 pm-1:40 pm

2 stops16h 46m

Palermo Punta Raisi

Thu 1/29

7:10 pm-6:59 pm

2 stops29h 49m

$709

ColumbiaPalermo

CAE - PMO

CAEPMO

Columbia Metropolitan

Fri 2/20

2:39 pm-11:40 am

2 stops15h 01m

Palermo Punta Raisi

Tue 2/24

6:10 am-9:31 pm

2 stops21h 21m

$715

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Thu 1/29

6:50 pm-10:40 pm

2 stops21h 50m

Palermo Punta Raisi

Thu 2/5

6:20 am-4:55 pm

2 stops16h 35m

$725

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/22

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/28

9:45 am-4:55 pm

2 stops37h 10m

$734

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/15

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/21

3:15 pm-4:55 pm

2 stops31h 40m

$753

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 1/18

6:50 pm-11:00 pm

2 stops22h 10m

Palermo Punta Raisi

Sun 1/25

6:25 pm-4:55 pm

1 stop28h 30m

$770

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 1/18

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 1/31

6:10 am-4:55 pm

2 stops16h 45m

$770

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Mon 1/19

6:50 pm-11:00 pm

2 stops22h 10m

Palermo Punta Raisi

Sun 1/25

6:10 am-4:55 pm

2 stops40h 45m

$770

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Mon 1/19

6:50 pm-11:00 pm

2 stops22h 10m

Palermo Punta Raisi

Sat 1/31

12:10 pm-4:55 pm

1 stop34h 45m

$770

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 21 results
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Best time to book a flight from South Carolina to Palermo

Have a flexible travel schedule? Discover the best time to fly to Palermo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Palermo

What is the cheapest time of day to fly from SC to PMO?

Find hourly flight availability from South Carolina to Palermo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from South Carolina to Palermo, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 41% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Palermo from South Carolina?

    Palermo Punta Raisi (PMO), located 15.2 mi from the city center, is the airport you fly into when you book flights from South Carolina to Palermo.

  • How long is the flight from South Carolina to Palermo?

    For as low as $715, Lufthansa can have you in Palermo from South Carolina in 15h 01m. Airlines will cover a distance of 5020 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Palermo?

    The most popular route from South Carolina to Palermo is Charlotte Douglas - Palermo Punta Raisi. You may also consider Myrtle Beach Intl - Palermo Punta Raisi or Columbia Metropolitan - Palermo Punta Raisi.

  • Can I find deals for flights from South Carolina to Palermo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Palermo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Palermo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Palermo.

  • Can I find deals for business class flights from South Carolina to Palermo?

    Yes. Cheapflights offers flight deals from South Carolina to Palermo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Palermo?

Book flights to Palermo if you plan to visit one of these locations
Agrigento
Cefalù

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Alternative routes for South Carolina to Palermo

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Top airline flying from South Carolina to Palermo

Discover the top airline that operate flights from South Carolina to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$635Average$1,459FlexibilityNo cancel feeOn-time76%

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