$432+ Cheap flights from Detroit (DTT) to Palermo (PMO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PMO
Jun 20 — Jun 271
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Palermo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Palermo
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Best
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Cheapest flights from Detroit to PalermoExplore the most affordable flight options available from Detroit to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
Explore the most affordable flight options available from Detroit to Palermo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 21, 2026.
This Turkish Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:50 pm
DTW
- PMO
1 stop15h 45m
Turkish Airlines
Thu 10/89:25 am
PMO
- DTW
1 stop15h 20m
Turkish Airlines
Deal found 5/18![Turkish Airlines logo]()
$849
This Cheapflightsfares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:00 am
DTW
- PMO
2 stops21h 05m
SWISS
Fri 8/219:45 am
PMO
- DTW
2 stops16h 40m
SWISS
Deal found 5/20![SWISS logo]()
$871
This Justfly.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:00 pm
DTW
- PMO
1 stop12h 20m
Multiple Airlines
Fri 8/219:45 am
PMO
- DTW
2 stops16h 40m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$899
This Cheapflightsfares deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:00 pm
DTW
- PMO
1 stop12h 20m
Lufthansa
Fri 8/2111:50 am
PMO
- DTW
2 stops18h 09m
Lufthansa
Deal found 5/19![Lufthansa logo]()
$910
This Cheapflightsfares deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:00 pm
DTW
- PMO
1 stop12h 30m
Lufthansa
Fri 8/2111:50 am
PMO
- DTW
2 stops18h 09m
Lufthansa
Deal found 5/20![Lufthansa logo]()
$911
This Mytrip deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:45 am
DTW
- PMO
3 stops27h 40m
Multiple Airlines
Wed 6/2411:15 pm
PMO
- DTW
3 stops30h 39m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$918
This Gotogate deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/258:50 pm
DTW
- PMO
1 stop29h 35m
Turkish Airlines
Sat 10/107:35 pm
PMO
- DTW
1 stop29h 10m
Turkish Airlines
Deal found 5/16![Turkish Airlines logo]()
$930
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:11 pm
DTW
- PMO
2 stops30h 04m
United Airlines
Thu 10/292:20 pm
PMO
- DTW
1 stop23h 09m
United Airlines
Deal found 5/19![United Airlines logo]()
$945
Best flights from Detroit to PalermoDiscover carefully curated flight deals from Detroit to Palermo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
Discover carefully curated flight deals from Detroit to Palermo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 21, 2026.
This Turkish Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:50 pm
DTW
- PMO
1 stop15h 45m
Turkish Airlines
Thu 10/89:25 am
PMO
- DTW
1 stop15h 20m
Turkish Airlines
Deal found 5/20![Turkish Airlines logo]()
$849
This KLM deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:20 pm
DTW
- PMO
1 stop11h 40m
Multiple Airlines
Mon 9/710:05 am
PMO
- DTW
1 stop33h 21m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$1,015
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1910:20 am
DTW
- PMO
2 stops38h 55m
United Airlines
Sat 10/109:45 am
PMO
- DTW
1 stop16h 52m
United Airlines
Deal found 5/17![United Airlines logo]()
$1,023
This British Airways deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:40 pm
DTW
- PMO
2 stops37h 40m
British Airways
Thu 10/112:05 pm
PMO
- DTW
2 stops40h 49m
British Airways
Deal found 5/18![British Airways logo]()
$1,354
This KLM deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:55 pm
DTW
- PMO
1 stop11h 45m
KLM
Thu 7/28:20 am
PMO
- DTW
1 stop35h 12m
KLM
Deal found 5/19![KLM logo]()
$1,504
This KLM deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/126:45 pm
DTW
- PMO
1 stop14h 15m
Multiple Airlines
Sun 8/93:10 pm
PMO
- DTW
1 stop28h 16m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$1,044
This KLM deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:55 pm
DTW
- PMO
1 stop12h 30m
KLM
Thu 7/308:20 am
PMO
- DTW
1 stop33h 20m
KLM
Deal found 5/18![KLM logo]()
$1,505
Last-minute flights from Detroit to PalermoDiscover last-minute flight deals from Detroit to Palermo. Data last updated May 21, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Palermo. Data last updated May 21, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:10 pm
DTW
- PMO
2 stops13h 35m
Multiple Airlines
Wed 7/2210:30 pm
PMO
- DTW
3 stops28h 55m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$963
This Mytrip deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:10 pm
DTW
- PMO
2 stops13h 35m
Multiple Airlines
Wed 8/511:15 pm
PMO
- DTW
3 stops28h 25m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$1,003
This Mytrip deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:10 pm
DTW
- PMO
2 stops14h 55m
Multiple Airlines
Wed 8/511:15 pm
PMO
- DTW
3 stops28h 25m
Multiple Airlines
Deal found 5/20![Multiple Airlines logo]()
$1,078
This Mytrip deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 pm
DTW
- PMO
2 stops20h 15m
Multiple Airlines
Tue 6/910:45 pm
PMO
- DTW
3 stops24h 35m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$1,038
This Mytrip deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:10 pm
DTW
- PMO
3 stops21h 25m
Multiple Airlines
Sun 6/2110:30 pm
PMO
- DTW
2 stops24h 50m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$949
This Mytrip deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:10 pm
DTW
- PMO
3 stops21h 25m
Multiple Airlines
Tue 6/2310:40 pm
PMO
- DTW
2 stops24h 40m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$1,050
This Mytrip deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:45 am
DTW
- PMO
3 stops27h 40m
Multiple Airlines
Wed 6/2411:15 pm
PMO
- DTW
3 stops30h 39m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$918
One-way flights from Detroit to PalermoSearch for one-way flight options from Detroit to Palermo. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
Search for one-way flight options from Detroit to Palermo. Find affordable one-way fares based on user searches. Data last updated May 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:10 pm
DTW
- PMO
3 stops37h 30m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:10 pm
DTW
- PMO
3 stops39h 10m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$445
This Mytrip deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:15 am
DTW
- PMO
2 stops16h 45m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$453
This Air France deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:15 pm
DTW
- PMO
1 stop15h 45m
Air France
Deal found 5/16![Air France logo]()
$463
This KLM deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:35 pm
DTW
- PMO
1 stop33h 50m
KLM
Deal found 5/18![KLM logo]()
$468
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 pm
DTW
- PMO
2 stops55h 05m
United Airlines
Deal found 5/18![United Airlines logo]()
$487
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:49 pm
DTW
- PMO
3 stops23h 56m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$507
This FlightHub deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:00 pm
DTW
- PMO
1 stop12h 20m
Lufthansa
Deal found 5/18![Lufthansa logo]()
$538
This Mytrip deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:15 am
DTW
- PMO
2 stops29h 20m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$664
Find flight deals from Detroit to Palermo
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTT) to Palermo (PMO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 21, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $849 (Turkish Airlines) |
One-way from | $432 (Kiwi.com) |
Popular in | June |
Cheapest in | April |
Average price | $1,090 |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Palermo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
Use the filters below to find and compare flights from Detroit to Palermo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Mon 9/14
8:50 pm-6:35 pm
1 stop15h 45m
Palermo Punta Raisi
Thu 10/8
9:25 am-6:45 pm
1 stop15h 20m
$849
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Thu 8/13
9:20 pm-3:00 pm
1 stop11h 40m
Palermo Punta Raisi
Mon 9/7
10:05 am-1:26 pm
1 stop33h 21m
$1,015
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Sat 9/19
10:20 am-7:15 am
2 stops38h 55m
Palermo Punta Raisi
Sat 10/10
9:45 am-8:37 pm
1 stop16h 52m
$1,023
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Sun 7/12
6:45 pm-3:00 pm
1 stop14h 15m
Palermo Punta Raisi
Sun 8/9
3:10 pm-1:26 pm
1 stop28h 16m
$1,044
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Sun 9/27
3:40 pm-11:20 am
2 stops37h 40m
Palermo Punta Raisi
Thu 10/1
12:05 pm-10:54 pm
2 stops40h 49m
$1,354
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Tue 6/16
7:55 pm-1:40 pm
1 stop11h 45m
Palermo Punta Raisi
Thu 7/2
8:20 am-1:32 pm
1 stop35h 12m
$1,504
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Mon 6/22
7:55 pm-2:25 pm
1 stop12h 30m
Palermo Punta Raisi
Thu 7/30
8:20 am-11:40 am
1 stop33h 20m
$1,505
Cheapest one-way
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Mon 8/24
6:10 pm-1:40 pm
3 stops37h 30m
$432
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Fri 6/12
6:10 pm-3:20 pm
3 stops39h 10m
$445
DetroitPalermo
DTW - PMO
DTWPMO
Detroit Metropolitan Wayne County
Sun 9/6
10:15 am-9:00 am
2 stops16h 45m
$453
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Detroit to Palermo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Palermo in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit-Palermo flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Detroit-Palermo flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Detroit-Palermo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit-Palermo flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit-Palermo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Palermo
Have a flexible travel schedule? Discover the best time to fly to Palermo from Detroit with our price prediction graph.
DTT-PMO
DTW-PMO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to Palermo
DTT-PMO
DTW-PMO
What is the cheapest month to book a flight from Detroit to Palermo?
Currently, December is the cheapest month in which you can book a flight from Detroit to Palermo (average of $550). Flying from Detroit to Palermo in June is currently the most expensive (average of $1,070). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Detroit to Palermo?
How far ahead should I book a flight from Detroit to Palermo?
To ensure you get the cheapest price possible for a flight from Detroit to Palermo, you should look to book at least 17 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Palermo
Get insights into the airlines that provide service to Palermo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Palermo. Reviews last updated May 21, 2026.
Read through reviews of airlines operating flights from Detroit to Palermo, such as KLM,Turkish Airlines, andLufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.4
Entertainment
7.2
Overall
7.8
Comfort
7.7
Boarding
7.8
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Entertainment
7.2
Overall
7.8
Comfort
7.7
Boarding
7.8
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Entertainment
7.2
Overall
7.8
Comfort
7.7
Boarding
7.8
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Crew
8.4
Entertainment
7.2
Overall
7.8
Comfort
7.7
Boarding
7.8
Food
7.3
Reviews
1 / 20
6.0
GoodAnonymous,Apr 2026
OKC - ATL
Related info for your journey
Find useful and relevant information for your journey from Detroit to Palermo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Palermo?
Book flights to Palermo if you plan to visit one of these locationsAgrigento
Cefalù
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Detroit and Palermo flights
Browse other Detroit and Palermo flight options. Last updated on May 21, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on May 21, 2026.
Other flights to Palermo
Explore flights to Palermo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Detroit to Palermo
Discover the top 3 airlines that operate flights from Detroit to Palermo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$585 | Average$796 | FlexibilityNo cancel fee | On-time77% | |
| Cheapest$649 | Average$1,125 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$784 | Average$954 | FlexibilityNo cancel fee | On-time76% |