HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
OR Tambo

$1,139+ Cheap flights from Myrtle Beach (MYR) to OR Tambo (JNB)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — JNB
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to OR Tambo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Myrtle Beach to OR Tambo

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to OR Tambo (JNB). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$1,139
(American Airlines)
From Myrtle Beach Intl to Johannesburg OR Tambo
Search Deals

Find flight deals from Myrtle Beach to OR Tambo

Cheapest flights from Myrtle Beach to OR Tambo
Explore the most affordable flight options available from Myrtle Beach to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:18 pmMYR - JNB
2 stops34h 07mAmerican Airlines
Wed 11/510:00 pmJNB - MYR
2 stops28h 27mAmerican Airlines
Deal found 9/14$1,139
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/291:43 pmMYR - JNB
3 stops32h 12mMultiple Airlines
Wed 11/58:20 pmJNB - MYR
2 stops28h 52mMultiple Airlines
Deal found 9/14$1,534
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:31 pmMYR - JNB
2 stops34h 04mQatar Airways
Sat 9/201:55 pmJNB - MYR
2 stops32h 56mQatar Airways
Deal found 9/14$1,721
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:58 pmMYR - JNB
2 stops35h 12mDelta
Wed 11/59:55 pmJNB - MYR
1 stop27h 08mDelta
Deal found 9/14$2,293
This Virgin Atlantic deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:36 amMYR - JNB
1 stop26h 24mVirgin Atlantic
Fri 11/710:00 pmJNB - MYR
2 stops32h 57mVirgin Atlantic
Deal found 9/16$3,703
This Virgin Atlantic deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:55 pmMYR - JNB
1 stop18h 45mVirgin Atlantic
Sat 9/208:40 pmJNB - MYR
2 stops27h 27mVirgin Atlantic
Deal found 9/14$3,804
This AranGrant deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AranGrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:54 pmMYR - JNB
2 stops36h 41mBritish Airways
Fri 11/77:35 pmJNB - MYR
2 stops29h 37mBritish Airways
Deal found 9/16$4,056
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:00 pmMYR - JNB
1 stop21h 00mDelta
Fri 11/79:55 pmJNB - MYR
1 stop24h 13mDelta
Deal found 9/16$6,206

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Johannesburg OR Tambo Airport that are best for you.

Fly from

Myrtle Beach

Fly to

OR Tambo

Route

Depart

Return

Price

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Wed 10/29

6:18 pm-10:25 am

2 stops34h 07m

Johannesburg OR Tambo

Wed 11/5

10:00 pm-7:27 pm

2 stops28h 27m

$1,139

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Thu 3/5

6:28 pm-10:25 am

2 stops32h 57m

Johannesburg OR Tambo

Mon 3/9

10:00 pm-9:10 pm

2 stops29h 10m

$1,257

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Wed 10/29

1:43 pm-3:55 am

3 stops32h 12m

Johannesburg OR Tambo

Wed 11/5

8:20 pm-6:12 pm

2 stops28h 52m

$1,534

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Thu 3/5

2:15 pm-7:00 pm

1 stop21h 45m

Johannesburg OR Tambo

Mon 3/9

7:40 pm-11:35 pm

2 stops33h 55m

$1,942

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Wed 10/29

6:58 pm-12:10 pm

2 stops35h 12m

Johannesburg OR Tambo

Wed 11/5

9:55 pm-6:03 pm

1 stop27h 08m

$2,293

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Fri 10/31

10:36 am-7:00 pm

1 stop26h 24m

Johannesburg OR Tambo

Fri 11/7

10:00 pm-11:57 pm

2 stops32h 57m

$3,703

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Fri 10/31

12:54 pm-7:35 am

2 stops36h 41m

Johannesburg OR Tambo

Fri 11/7

7:35 pm-6:12 pm

2 stops29h 37m

$4,056

Myrtle BeachJohannesburg

MYR - JNB

MYRJNB

Myrtle Beach Intl

Fri 10/31

4:00 pm-7:00 pm

1 stop21h 00m

Johannesburg OR Tambo

Fri 11/7

9:55 pm-3:08 pm

1 stop24h 13m

$6,206

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Myrtle Beach to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Johannesburg OR Tambo?

    Located just 2.1 mi from the city center, Myrtle Beach Intl is the airport most travelers will use when flying to Johannesburg OR Tambo from Myrtle Beach. Booking flights from Myrtle Beach Intl (MYR) to Johannesburg OR Tambo should be relatively easy as there are 0 daily outbound flights to Johannesburg OR Tambo from 0 different airlines.

  • How long is the flight from Myrtle Beach to Johannesburg OR Tambo Airport?

    American Airlines can get you from Myrtle Beach to Johannesburg OR Tambo Airport in just under 34h 07m. Your travel time can differ by up to . Airlines will cover a distance of 8126 mi.

  • Can I find deals for flights from Myrtle Beach to OR Tambo that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to OR Tambo.

  • Can I find deals for business class flights from Myrtle Beach to OR Tambo?

    Yes. Cheapflights offers flight deals from Myrtle Beach to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Johannesburg OR Tambo Airport?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Johannesburg OR Tambo Airport (average of $1,173). Flying from Myrtle Beach to Johannesburg OR Tambo Airport in July is currently the most expensive (average of $1,674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to OR Tambo flights
Savannah to OR Tambo flights
Charleston to OR Tambo flights
Augusta to OR Tambo flights
Columbia to OR Tambo flights
Greenville to OR Tambo flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.