$178+ Cheap flights from San Antonio (SAT) to Odessa, TX
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — MAF
Jun 17 — Jun 241
Round-trip
1 adult, Economy
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Best
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Cheapest flights from San Antonio to OdessaExplore the most affordable flight options available from San Antonio to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from San Antonio to Odessa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:01 am
SAT
- MAF
1 stop5h 08m
American Airlines
Wed 6/178:23 pm
MAF
- SAT
1 stop3h 36m
American Airlines
Deal found 5/13![American Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:20 pm
SAT
- MAF
1 stop5h 10m
Southwest
Wed 6/173:30 pm
MAF
- SAT
2 stops6h 50m
Southwest
Deal found 5/13![Southwest logo]()
$340
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:45 am
SAT
- MAF
1 stop3h 10m
Southwest
Wed 6/176:10 pm
MAF
- SAT
1 stop6h 20m
Southwest
Deal found 5/14![Southwest logo]()
$375
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:23 pm
SAT
- MAF
1 stop3h 36m
American Airlines
Mon 6/226:47 pm
MAF
- SAT
1 stop5h 12m
American Airlines
Deal found 5/18![American Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:30 am
SAT
- MAF
1 stop5h 25m
Southwest
Mon 6/222:35 pm
MAF
- SAT
2 stops6h 25m
Southwest
Deal found 5/15![Southwest logo]()
$400
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:01 am
SAT
- MAF
1 stop5h 05m
American Airlines
Sun 6/145:00 am
MAF
- SAT
1 stop3h 50m
American Airlines
Deal found 5/15![American Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:45 am
SAT
- MAF
1 stop3h 10m
Southwest
Fri 6/126:05 am
MAF
- SAT
1 stop6h 20m
Southwest
Deal found 5/17![Southwest logo]()
$415
Best flights from San Antonio to OdessaDiscover carefully curated flight deals from San Antonio to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from San Antonio to Odessa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:01 am
SAT
- MAF
1 stop5h 08m
American Airlines
Wed 6/178:23 pm
MAF
- SAT
1 stop3h 36m
American Airlines
Deal found 5/13![American Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:45 am
SAT
- MAF
1 stop3h 10m
Southwest
Wed 6/176:10 pm
MAF
- SAT
1 stop6h 20m
Southwest
Deal found 5/14![Southwest logo]()
$375
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/209:37 am
SAT
- MAF
1 stop6h 38m
United Airlines
Mon 6/227:13 pm
MAF
- SAT
1 stop3h 29m
United Airlines
Deal found 5/18![United Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/412:50 pm
SAT
- MAF
1 stop7h 10m
Southwest
Mon 7/65:15 am
MAF
- SAT
2 stops5h 10m
Southwest
Deal found 5/14![Southwest logo]()
$380
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:23 pm
SAT
- MAF
1 stop3h 36m
American Airlines
Mon 6/226:47 pm
MAF
- SAT
1 stop5h 12m
American Airlines
Deal found 5/18![American Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:15 pm
SAT
- MAF
1 stop5h 50m
Southwest
Sat 7/253:20 pm
MAF
- SAT
1 stop8h 55m
Southwest
Deal found 5/13![Southwest logo]()
$395
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:30 pm
SAT
- MAF
1 stop5h 35m
Southwest
Mon 6/226:05 am
MAF
- SAT
1 stop6h 20m
Southwest
Deal found 5/14![Southwest logo]()
$395
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:30 am
SAT
- MAF
1 stop5h 25m
Southwest
Mon 6/222:35 pm
MAF
- SAT
2 stops6h 25m
Southwest
Deal found 5/15![Southwest logo]()
$400
Last-minute flights from San Antonio to OdessaDiscover last-minute flight deals from San Antonio to Odessa. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Odessa. Data last updated May 18, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:45 am
SAT
- MAF
1 stop3h 10m
Southwest
Fri 6/126:05 am
MAF
- SAT
1 stop6h 20m
Southwest
Deal found 5/17![Southwest logo]()
$415
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:01 am
SAT
- MAF
1 stop5h 08m
American Airlines
Wed 6/178:23 pm
MAF
- SAT
1 stop3h 36m
American Airlines
Deal found 5/13![American Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:20 pm
SAT
- MAF
1 stop5h 10m
Southwest
Wed 6/173:30 pm
MAF
- SAT
2 stops6h 50m
Southwest
Deal found 5/13![Southwest logo]()
$340
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:45 am
SAT
- MAF
1 stop3h 10m
Southwest
Wed 6/176:10 pm
MAF
- SAT
1 stop6h 20m
Southwest
Deal found 5/14![Southwest logo]()
$375
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:01 am
SAT
- MAF
1 stop5h 05m
American Airlines
Sun 6/145:00 am
MAF
- SAT
1 stop3h 50m
American Airlines
Deal found 5/15![American Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:30 am
SAT
- MAF
1 stop5h 25m
Southwest
Mon 6/222:35 pm
MAF
- SAT
2 stops6h 25m
Southwest
Deal found 5/15![Southwest logo]()
$400
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:23 pm
SAT
- MAF
1 stop3h 36m
American Airlines
Mon 6/226:47 pm
MAF
- SAT
1 stop5h 12m
American Airlines
Deal found 5/18![American Airlines logo]()
$395
One-way flights from San Antonio to OdessaSearch for one-way flight options from San Antonio to Odessa. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from San Antonio to Odessa. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:07 pm
SAT
- MAF
1 stop4h 52m
American Airlines
Deal found 5/16![American Airlines logo]()
$178
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:40 am
SAT
- MAF
2 stops7h 30m
Southwest
Deal found 5/16![Southwest logo]()
$183
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:30 pm
SAT
- MAF
1 stop4h 04m
American Airlines
Deal found 5/17![American Airlines logo]()
$198
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
SAT
- MAF
2 stops6h 15m
Southwest
Deal found 5/17![Southwest logo]()
$203
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:20 pm
SAT
- MAF
1 stop4h 24m
United Airlines
Deal found 5/15![United Airlines logo]()
$260
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:40 am
SAT
- MAF
2 stops7h 30m
Southwest
Deal found 5/15![Southwest logo]()
$265
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:31 am
SAT
- MAF
1 stop4h 20m
American Airlines
Deal found 5/14![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/251:35 pm
SAT
- MAF
2 stops5h 20m
Southwest
Deal found 5/14![Southwest logo]()
$350
Find flight deals from San Antonio to Odessa
Keep the following information in mind while searching for San Antonio to Odessa flight deals. Data was last updated May 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $335 (American Airlines) |
One-way from | $178 (American Airlines) |
Popular in | January |
Cheapest in | June |
Average price | $289 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Odessa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from San Antonio to Odessa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Wed 6/10
6:01 am-11:09 am
1 stop5h 08m
Midland Intl
Wed 6/17
8:23 pm-11:59 pm
1 stop3h 36m
$335
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Thu 6/11
9:45 am-12:55 pm
1 stop3h 10m
Midland Intl
Wed 6/17
6:10 pm-12:30 am
1 stop6h 20m
$375
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Sat 7/4
12:50 pm-8:00 pm
1 stop7h 10m
Midland Intl
Mon 7/6
5:15 am-10:25 am
2 stops5h 10m
$380
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Sat 6/20
9:37 am-4:15 pm
1 stop6h 38m
Midland Intl
Mon 6/22
7:13 pm-10:42 pm
1 stop3h 29m
$395
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Thu 6/18
8:23 pm-11:59 pm
1 stop3h 36m
Midland Intl
Mon 6/22
6:47 pm-11:59 pm
1 stop5h 12m
$395
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Sun 7/19
6:15 pm-12:05 am
1 stop5h 50m
Midland Intl
Sat 7/25
3:20 pm-12:15 am
1 stop8h 55m
$395
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 6/19
6:30 pm-12:05 am
1 stop5h 35m
Midland Intl
Mon 6/22
6:05 am-12:25 pm
1 stop6h 20m
$395
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Mon 6/15
5:30 am-10:55 am
1 stop5h 25m
Midland Intl
Mon 6/22
2:35 pm-9:00 pm
2 stops6h 25m
$400
Cheapest one-way
Quickest one-way
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 8/28
6:30 pm-10:34 pm
1 stop4h 04m
$198
San AntonioMidland
SAT - MAF
SATMAF
San Antonio
Fri 8/28
6:00 am-12:15 pm
2 stops6h 15m
$203
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from San Antonio to Odessa
Have a flexible travel schedule? Discover the best time to fly to Odessa from San Antonio with our price prediction graph.
SAT-MAF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Odessa
SAT-OD3
SAT-MAF
How much does it cost to fly round-trip from San Antonio to Odessa?
Reviews of airlines servicing Odessa
Get insights into the airlines that provide service to Odessa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Odessa. Reviews last updated May 18, 2026.
See what other customers who have flown with Southwest and American Airlines from San Antonio to Odessa have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Odessa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Antonio to Odessa
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Complete your trip
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San Antonio and Odessa flights
Browse other San Antonio and Odessa flight options. Last updated on May 18, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on May 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Antonio to Odessa flights
Consider these flights traveling from San Antonio to Odessa.
Top 2 airlines flying from San Antonio to Odessa
Discover the top 2 airlines that operate flights from San Antonio to Odessa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$182 | Average$457 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$527 | FlexibilityNo cancel fee | On-time71% |