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Panama City

$325+ Cheap flights from Santiago de los Caballeros (STI) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
STI — ECP
Mar 19 — Mar 261
Thu 3/19
Thu 3/26
1 adult, Economy
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Cheap flight deals from Santiago de los Caballeros to Panama City

One-way flights from Santiago de los Caballeros to Panama City
Search for one-way flight options from Santiago de los Caballeros to Panama City. Find affordable one-way fares based on user searches. Data last updated February 17, 2026.

This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:10 am
STI
-
ECP
2 stops13h 26m
Delta
Deal found 2/14$325
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:32 pm
STI
-
ECP
3 stops11h 14m
American Airlines
Deal found 2/15$1,572

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Santiago de los Caballeros to Panama City that are best for you.

Fly from

Santiago de los Caballeros

Fly to

Panama City

Route

Depart

Return

Price

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Wed 5/13

6:10 am-6:36 pm

2 stops13h 26m

$325

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Wed 5/13

1:32 pm-11:46 pm

3 stops11h 14m

$1,572

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/13

Best time to book a flight from Santiago de los Caballeros to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago de los Caballeros with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Santiago de los Caballeros to Panama City that include hotel bookings?

    Yes. In addition to deals on Santiago de los Caballeros to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago de los Caballeros to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to Panama City.

  • Can I find deals for business class flights from Santiago de los Caballeros to Panama City?

    Yes. Cheapflights offers flight deals from Santiago de los Caballeros to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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