In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

What is the cheapest time of day to fly from STI to ECP?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago de los Caballeros to Panama City, Florida as you normally would.

How can I find direct flights from Santiago de los Caballeros to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to Panama City.

Can I find deals for business class flights from Santiago de los Caballeros to Panama City?

Yes. Cheapflights offers flight deals from Santiago de los Caballeros to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$490+ Flights from Santiago de los Caballeros to Panama City, FL

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Best flights from Santiago de los Caballeros to Panama City
Discover carefully curated flight deals from Santiago de los Caballeros to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 17, 2025.

Fri 1/309:59 pmSTI - ECP

2 stops16h 25mDelta

Tue 2/34:45 pmECP - STI

2 stops18h 19mDelta

Deal found 11/16

$490

Mon 5/116:10 amSTI - ECP

2 stops12h 40mDelta

Tue 5/127:05 pmECP - STI

2 stops16h 00mDelta

Deal found 11/14

$601

Cheap flight deals from Santiago de los Caballeros to Panama City

Round-trip from	$490 (Delta)

From Santiago de los Caballeros to Panama City NW Florida Beaches

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Use the filters below to find and compare flights from Santiago de los Caballeros to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 1/30

9:59 pm-12:24 pm

2 stops16h 25m

Panama City NW Florida Beaches

Tue 2/3

4:45 pm-1:04 pm

2 stops18h 19m

$490

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Mon 5/11

6:10 am-5:50 pm

2 stops12h 40m

Panama City NW Florida Beaches

Tue 5/12

7:05 pm-12:05 pm

2 stops16h 00m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Best time to book a flight from Santiago de los Caballeros to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago de los Caballeros with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Santiago de los Caballeros to Panama City, Florida?
A quick flight from Santiago de los Caballeros to Panama City, Florida can take about 16h 25m. Delta provides one of the quickest options available for as low as $490. Airlines will cover a distance of 1213 mi.
Can I find deals for flights from Santiago de los Caballeros to Panama City that include hotel bookings?
Yes. In addition to deals on Santiago de los Caballeros to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago de los Caballeros to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago de los Caballeros to Panama City.
Can I find deals for business class flights from Santiago de los Caballeros to Panama City?
Yes. Cheapflights offers flight deals from Santiago de los Caballeros to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago de los Caballeros to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Santiago de los Caballeros to Panama City

Best flights from Santiago de los Caballeros to Panama City
Discover carefully curated flight deals from Santiago de los Caballeros to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 17, 2025.

Discover carefully curated flight deals from Santiago de los Caballeros to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 17, 2025.

Cheap flight deals from Santiago de los Caballeros to Panama City

Round-trip from

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Use the filters below to find and compare flights from Santiago de los Caballeros to Panama City that are best for you.

Best time to book a flight from Santiago de los Caballeros to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago de los Caballeros with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santiago de los Caballeros to Panama City, Florida?

Can I find deals for flights from Santiago de los Caballeros to Panama City that include hotel bookings?

How can I find direct flights from Santiago de los Caballeros to Panama City?

Can I find deals for business class flights from Santiago de los Caballeros to Panama City?

Traveling to a place near Panama City?

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Alternative routes for Santiago de los Caballeros to Panama City

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Complete your trip

Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Santiago de los Caballeros to Panama City by cabin class

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Santiago de los Caballeros and Panama City flights

Browse other Santiago de los Caballeros and Panama City flight options. Last updated on November 17, 2025.

Other flights from Santiago de los Caballeros

Browse through other flights departing from Santiago de los Caballeros. Flights are based on user searches made on Cheapflights and were last updated on November 17, 2025.

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$490+ Cheap flights from Santiago de los Caballeros (STI) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santiago de los Caballeros to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Santiago de los Caballeros to Panama City

Best flights from Santiago de los Caballeros to Panama CityDiscover carefully curated flight deals from Santiago de los Caballeros to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 17, 2025.

Discover carefully curated flight deals from Santiago de los Caballeros to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 17, 2025.

Cheap flight deals from Santiago de los Caballeros to Panama City

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago de los Caballeros to Panama City that are best for you.

Best time to book a flight from Santiago de los Caballeros to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago de los Caballeros with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Santiago de los Caballeros to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Santiago de los Caballeros to Panama City, Florida?

Can I find deals for flights from Santiago de los Caballeros to Panama City that include hotel bookings?

How can I find direct flights from Santiago de los Caballeros to Panama City?

Can I find deals for business class flights from Santiago de los Caballeros to Panama City?

Traveling to a place near Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santiago de los Caballeros to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Best flights from Santiago de los Caballeros to Panama City
Discover carefully curated flight deals from Santiago de los Caballeros to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 17, 2025.