What are the cheapest airlines to fly from Missouri to Brussels Bruxelles-National Airport one-way?

To fly one-way, consider booking your trip with Air Canada, which is currently one of the cheapest options available, starting at $464. Brussels Airlines flights start at $465 while deals on British Airways start at $1,966 one-way.

In terms of precipitation, rainfall in Brussels Bruxelles-National Airport ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels Bruxelles-National Airport when rainfall is around 1.6 in.

If weather is an important factor for your trip to Brussels Bruxelles-National Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?

The most popular flight routes from Missouri to Brussels Bruxelles-National Airport are Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National and Joplin - Brussels Bruxelles-National.

What is the cheapest month to fly from Missouri to Brussels Bruxelles-National Airport?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, October can be a great choice for travel to Brussels Bruxelles-National Airport. Flights to Brussels Bruxelles-National Airport from Missouri in October are about $1,020 on average during October, but can be found for as low as $659.

Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?

Yes. In addition to deals on Missouri to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Bruxelles-National?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Bruxelles-National.

Can I find deals for business class flights from Missouri to Bruxelles-National?

Yes. Cheapflights offers flight deals from Missouri to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$339+ Flights from Missouri to Brussels Bruxelles-National Airport

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Cheap flight deals from Missouri to Bruxelles-National

Round-trip from	$583 (United Airlines)
One-way from	$339 (Kiwi.com)
Popular in	December
Cheapest in	October
Average price	$1,139

From Missouri to Brussels Bruxelles-National

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One-way flight from Missouri to Brussels Bruxelles-National

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Highest demand for flights based on searches. 11% potential increase in price ($135 potential increase over avg. RT price).

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Cheapest flight prices on average. 7% potential price decrease ($72 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Missouri to Bruxelles-National

Cheapest flights from Missouri to Bruxelles-National
Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.

Wed 11/127:00 amSTL - BRU

2 stops17h 50mUnited Airlines

Thu 11/2710:00 amBRU - STL

2 stops35h 25mUnited Airlines

Deal found 8/20

$583

Fri 11/144:05 pmSTL - BRU

2 stops56h 45mMultiple Airlines

Mon 11/247:55 pmBRU - STL

2 stops34h 49mMultiple Airlines

Deal found 8/20

$631

Mon 12/158:00 amSTL - BRU

2 stops16h 50mUnited Airlines

Thu 12/2510:00 amBRU - STL

2 stops35h 26mUnited Airlines

Deal found 8/20

$663

Fri 11/1412:31 pmSTL - BRU

1 stop13h 24mUnited Airlines

Mon 11/2410:00 amBRU - STL

2 stops36h 46mUnited Airlines

Deal found 8/20

$683

Fri 10/2411:33 amMCI - BRU

1 stop14h 27mUnited Airlines

Tue 10/2810:00 amBRU - MCI

2 stops34h 21mUnited Airlines

Deal found 8/20

$703

Wed 11/1211:49 amSTL - BRU

1 stop13h 16mLufthansa

Thu 11/277:30 pmBRU - STL

1 stop25h 25mLufthansa

Deal found 8/20

$719

Wed 9/241:30 pmSTL - BRU

1 stop11h 35mAir Canada

Wed 10/810:00 amBRU - STL

1 stop16h 57mAir Canada

Deal found 8/21

$731

Wed 9/241:30 pmSTL - BRU

2 stops13h 15mMultiple Airlines

Wed 10/810:00 amBRU - STL

2 stops16h 38mMultiple Airlines

Deal found 8/21

$741

Fri 11/147:45 amJLN - BRU

2 stops17h 05mUnited Airlines

Tue 11/1810:00 amBRU - JLN

2 stops44h 30mUnited Airlines

Deal found 8/21

$939

Fri 12/197:45 amMCI - BRU

2 stops17h 20mUnited Airlines

Tue 12/3010:00 amBRU - MCI

2 stops38h 41mUnited Airlines

Deal found 8/21

$1,102

Fri 10/247:30 amMCI - BRU

2 stops17h 35mMultiple Airlines

Tue 10/287:00 amBRU - MCI

3 stops20h 50mMultiple Airlines

Deal found 8/20

$1,233

Mon 8/256:00 amMCI - BRU

3 stops31h 05mMultiple Airlines

Wed 8/271:50 pmBRU - MCI

3 stops35h 17mMultiple Airlines

Deal found 8/21

$1,522

Best flights from Missouri to Bruxelles-National
Discover carefully curated flight deals from Missouri to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2025.

Wed 11/126:30 amSTL - BRU

1 stop19h 25mUnited Airlines

Thu 11/2710:00 amBRU - STL

2 stops33h 28mUnited Airlines

Deal found 8/20

$583

Fri 11/144:05 pmSTL - BRU

2 stops56h 45mMultiple Airlines

Mon 11/247:55 pmBRU - STL

2 stops34h 49mMultiple Airlines

Deal found 8/20

$631

Mon 12/1510:00 amSTL - BRU

2 stops14h 50mAir Canada

Thu 12/2510:00 amBRU - STL

2 stops36h 29mAir Canada

Deal found 8/21

$683

Wed 11/1211:49 amSTL - BRU

1 stop13h 16mLufthansa

Thu 11/277:30 pmBRU - STL

1 stop25h 25mLufthansa

Deal found 8/20

$719

Mon 12/158:00 amSTL - BRU

2 stops16h 50mUnited Airlines

Thu 12/2510:00 amBRU - STL

2 stops35h 26mUnited Airlines

Deal found 8/20

$663

Fri 10/246:00 amMCI - BRU

2 stops19h 05mAir Canada

Tue 10/2810:00 amBRU - MCI

2 stops28h 56mAir Canada

Deal found 8/20

$726

Fri 11/1412:31 pmSTL - BRU

1 stop13h 24mUnited Airlines

Mon 11/2410:00 amBRU - STL

2 stops36h 46mUnited Airlines

Deal found 8/20

$683

Fri 10/2411:33 amMCI - BRU

1 stop14h 27mUnited Airlines

Tue 10/2810:00 amBRU - MCI

2 stops34h 21mUnited Airlines

Deal found 8/20

$703

Fri 10/247:30 amMCI - BRU

2 stops17h 35mMultiple Airlines

Tue 10/287:00 amBRU - MCI

3 stops20h 50mMultiple Airlines

Deal found 8/20

$1,233

Fri 11/147:45 amJLN - BRU

1 stop18h 10mUnited Airlines

Tue 11/1810:00 amBRU - JLN

2 stops44h 30mUnited Airlines

Deal found 8/19

$939

Fri 12/197:45 amMCI - BRU

2 stops17h 20mUnited Airlines

Tue 12/3010:00 amBRU - MCI

2 stops38h 41mUnited Airlines

Deal found 8/20

$1,102

Fri 12/197:45 amMCI - BRU

3 stops17h 05mMultiple Airlines

Tue 12/3010:00 amBRU - MCI

2 stops18h 50mMultiple Airlines

Deal found 8/20

$1,628

Last-minute flights from Missouri to Bruxelles-National
Discover last-minute flight deals from Missouri to Bruxelles-National. Data last updated August 22, 2025 and is based on user searches.

Mon 8/256:00 amMCI - BRU

3 stops31h 05mMultiple Airlines

Wed 8/271:50 pmBRU - MCI

3 stops35h 17mMultiple Airlines

Deal found 8/21

$1,522

Wed 9/241:30 pmSTL - BRU

1 stop11h 35mAir Canada

Wed 10/810:00 amBRU - STL

1 stop16h 57mAir Canada

Deal found 8/21

$731

Wed 9/241:30 pmSTL - BRU

2 stops13h 15mMultiple Airlines

Wed 10/810:00 amBRU - STL

2 stops16h 38mMultiple Airlines

Deal found 8/21

$741

Wed 9/246:40 amSTL - BRU

2 stops19h 00mDelta

Wed 10/810:45 amBRU - STL

1 stop18h 19mDelta

Deal found 8/22

$751

One-way flights from Missouri to Bruxelles-National
Search for one-way flight options from Missouri to Bruxelles-National. Find affordable one-way fares based on user searches. Data last updated August 22, 2025.

Wed 10/82:55 pmMCI - BRU

3 stops44h 55mMultiple Airlines

Deal found 8/21

$339

Wed 10/87:30 amMCI - BRU

2 stops17h 35mAir Canada

Deal found 8/21

$464

Wed 10/812:40 pmMCI - BRU

1 stop11h 35mBrussels Airlines

Deal found 8/21

$465

Sun 11/24:14 pmSTL - BRU

3 stops44h 46mMultiple Airlines

Deal found 8/21

$1,570

Sat 11/17:00 amSTL - BRU

3 stops54h 55mMultiple Airlines

Deal found 8/21

$1,650

Sat 11/14:25 pmSTL - BRU

2 stops22h 25mBritish Airways

Deal found 8/21

$1,966

Wed 9/173:35 pmSTL - BRU

3 stops59h 20mMultiple Airlines

Deal found 8/20

$2,126

Wed 9/1712:28 pmSTL - BRU

2 stops27h 02mIberia

Deal found 8/20

$2,308

Sun 11/21:10 pmSTL - BRU

1 stop11h 05mBrussels Airlines

Deal found 8/21

$3,072

Sat 11/111:49 amSTL - BRU

1 stop14h 16mLufthansa

Deal found 8/21

$3,076

Wed 9/1711:27 amSTL - BRU

1 stop13h 18mAustrian Airlines

Deal found 8/20

$3,437

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Wed 11/12

6:30 am-8:55 am

1 stop19h 25m

Brussels Bruxelles-National

Thu 11/27

10:00 am-12:28 pm

2 stops33h 28m

$583

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Fri 11/14

4:05 pm-7:50 am

2 stops56h 45m

Brussels Bruxelles-National

Mon 11/24

7:55 pm-11:44 pm

2 stops34h 49m

$631

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Mon 12/15

8:00 am-7:50 am

2 stops16h 50m

Brussels Bruxelles-National

Thu 12/25

10:00 am-2:26 pm

2 stops35h 26m

$663

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Mon 12/15

10:00 am-7:50 am

2 stops14h 50m

Brussels Bruxelles-National

Thu 12/25

10:00 am-3:29 pm

2 stops36h 29m

$683

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Fri 11/14

12:31 pm-8:55 am

1 stop13h 24m

Brussels Bruxelles-National

Mon 11/24

10:00 am-3:46 pm

2 stops36h 46m

$683

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Fri 10/24

11:33 am-9:00 am

1 stop14h 27m

Brussels Bruxelles-National

Tue 10/28

10:00 am-2:21 pm

2 stops34h 21m

$703

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Wed 11/12

11:49 am-8:05 am

1 stop13h 16m

Brussels Bruxelles-National

Thu 11/27

7:30 pm-1:55 pm

1 stop25h 25m

$719

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Fri 10/24

6:00 am-8:05 am

2 stops19h 05m

Brussels Bruxelles-National

Tue 10/28

10:00 am-8:56 am

2 stops28h 56m

$726

JoplinBrussels

JLN - BRU

JLNBRU

Joplin

Fri 11/14

7:45 am-8:55 am

1 stop18h 10m

Brussels Bruxelles-National

Tue 11/18

10:00 am-11:30 pm

2 stops44h 30m

$939

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Fri 12/19

7:45 am-8:05 am

2 stops17h 20m

Brussels Bruxelles-National

Tue 12/30

10:00 am-5:41 pm

2 stops38h 41m

$1,102

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/21

Showing 1-10 of 23 results

Best time to book a flight from Missouri to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels Bruxelles-National Airport

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

Currently, November is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $614). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,079). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BRU?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Brussels Bruxelles-National Airport as you normally would.

Related info for your journey

How long is the flight from Missouri to Brussels Bruxelles-National Airport?
Departing from Missouri to Brussels Bruxelles-National Airport will take you 19h 05m. Missouri and Brussels Bruxelles-National Airport are separated by a distance of 4528 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from Missouri to Brussels Bruxelles-National Airport one-way?
To fly one-way, consider booking your trip with Air Canada, which is currently one of the cheapest options available, starting at $464. Brussels Airlines flights start at $465 while deals on British Airways start at $1,966 one-way.
What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?
The most popular flight routes from Missouri to Brussels Bruxelles-National Airport are Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National and Joplin - Brussels Bruxelles-National.
Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?
Yes. In addition to deals on Missouri to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Bruxelles-National?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Bruxelles-National.
Can I find deals for business class flights from Missouri to Bruxelles-National?
Yes. Cheapflights offers flight deals from Missouri to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?
Currently, November is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $614). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,079). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Charleroi

Mons

Mechelen

Zaventem

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Missouri to Bruxelles-National

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$640	Average$1,033	FlexibilityNo cancel fee	On-time69%

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$339+ Cheap flights from Missouri to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Bruxelles-National with Cheapflights

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Cheap flight deals from Missouri to Bruxelles-National

Keep the following information in mind while searching for Missouri to Bruxelles-National flight deals. Data was last updated August 22, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Bruxelles-National

Cheapest flights from Missouri to Bruxelles-NationalExplore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.

Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Brussels Bruxelles-National Airport that are best for you.

Best time to book a flight from Missouri to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels Bruxelles-National Airport

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

What is the cheapest time of day to fly from MO to BRU?

Find hourly flight availability from Missouri to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 22, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Brussels Bruxelles-National Airport?

What are the cheapest airlines to fly from Missouri to Brussels Bruxelles-National Airport one-way?

What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?

Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?

How can I find direct flights from Missouri to Bruxelles-National?

Can I find deals for business class flights from Missouri to Bruxelles-National?

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

Traveling to a place near Brussels Bruxelles-National Airport?

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Alternative routes for Missouri to Bruxelles-National

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Top airline flying from Missouri to Bruxelles-National

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Cheapest flights from Missouri to Bruxelles-National
Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.