In terms of precipitation, rainfall in Brussels Bruxelles-National Airport ranges from 1.6 - 3.1 inches per month. January is typically the wettest month, when rainfall can reach 3.1 in. August is typically the driest time to visit Brussels Bruxelles-National Airport when rainfall is around 1.6 in.

If weather is an important factor for your trip to Brussels Bruxelles-National Airport, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 37.4 F).

What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?

The most popular flight routes from Missouri to Brussels Bruxelles-National Airport are Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National and Springfield-Branson - Brussels Bruxelles-National.

Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?

Yes. In addition to deals on Missouri to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Bruxelles-National?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Bruxelles-National.

Can I find deals for business class flights from Missouri to Bruxelles-National?

Yes. Cheapflights offers flight deals from Missouri to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$408+ Flights from Missouri to Brussels Bruxelles-National Airport

Q: How much does it cost to fly round-trip from Missouri to Brussels Bruxelles-National Airport?

Airfare is below average for this route at the moment. Missouri to Brussels Bruxelles-National Airport flights typically cost between $1,556 and $2,267 in January. The cheapest round-trip price found within the last 3 days was $421 on Multiple Airlines (Jan 13-Jan 20).

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Cheap flight deals from Missouri to Bruxelles-National

Cheapest flights from Missouri to Bruxelles-National
Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Mon 12/154:49 pmSTL - BRU

2 stops16h 51mAmerican Airlines

Thu 12/2510:15 amBRU - STL

2 stops29h 20mAmerican Airlines

Deal found 12/2

$545

Mon 12/158:30 amSTL - BRU

1 stop15h 45mUnited Airlines

Thu 12/2510:10 amBRU - STL

1 stop16h 08mUnited Airlines

Deal found 12/3

$749

Mon 12/151:00 pmSTL - BRU

2 stops17h 35mLufthansa

Thu 12/2510:10 amBRU - STL

1 stop18h 33mLufthansa

Deal found 12/2

$865

Thu 12/46:00 amMCI - BRU

2 stops28h 55mMultiple Airlines

Tue 12/99:50 amBRU - MCI

2 stops18h 35mMultiple Airlines

Deal found 12/1

$907

Wed 12/245:07 pmMCI - BRU

2 stops37h 08mUnited Airlines

Mon 12/2911:55 amBRU - MCI

1 stop15h 36mUnited Airlines

Deal found 12/3

$908

Mon 12/154:05 pmSTL - BRU

2 stops14h 30mAir Canada

Thu 12/2510:00 amBRU - STL

2 stops36h 29mAir Canada

Deal found 12/3

$913

Wed 12/2411:24 amMCI - BRU

1 stop14h 31mMultiple Airlines

Mon 12/2911:55 amBRU - MCI

1 stop15h 36mMultiple Airlines

Deal found 12/3

$1,181

Mon 12/1510:56 amSTL - BRU

2 stops22h 44mBritish Airways

Thu 12/2510:15 amBRU - STL

2 stops19h 41mBritish Airways

Deal found 12/4

$1,227

Thu 12/411:36 amMCI - BRU

1 stop14h 19mLufthansa

Tue 12/911:55 amBRU - MCI

1 stop14h 59mLufthansa

Deal found 12/1

$1,564

Fri 12/195:46 pmMCI - BRU

2 stops32h 09mUnited Airlines

Tue 12/3010:10 amBRU - MCI

1 stop18h 40mUnited Airlines

Deal found 12/3

$1,810

Sat 12/204:05 pmSTL - BRU

2 stops32h 45mAir Canada

Fri 1/210:00 amBRU - STL

2 stops36h 29mAir Canada

Deal found 12/2

$1,814

Sun 12/214:05 pmSTL - BRU

2 stops32h 45mAir Canada

Fri 1/210:00 amBRU - STL

2 stops36h 29mAir Canada

Deal found 12/3

$1,828

Best flights from Missouri to Bruxelles-National
Discover carefully curated flight deals from Missouri to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

Tue 1/1312:44 pmSTL - BRU

1 stop11h 31mMultiple Airlines

Tue 1/206:30 amBRU - STL

2 stops24h 29mMultiple Airlines

Deal found 12/2

$421

Tue 1/138:05 amSTL - BRU

2 stops16h 45mAir Canada

Tue 1/2010:00 amBRU - STL

2 stops35h 30mAir Canada

Deal found 12/2

$441

Wed 2/410:50 amMCI - BRU

2 stops22h 30mBritish Airways

Wed 2/1111:50 amBRU - MCI

2 stops18h 22mBritish Airways

Deal found 12/3

$458

Wed 2/49:05 amMCI - BRU

2 stops15h 45mUnited Airlines

Wed 2/1110:10 amBRU - MCI

1 stop14h 31mUnited Airlines

Deal found 12/3

$461

Tue 1/1311:22 amSTL - BRU

1 stop13h 43mLufthansa

Tue 1/2011:15 amBRU - STL

1 stop19h 44mLufthansa

Deal found 12/2

$467

Fri 2/64:05 pmSTL - BRU

2 stops14h 10mAir Canada

Tue 2/1010:00 amBRU - STL

2 stops35h 30mAir Canada

Deal found 12/3

$461

Fri 2/63:11 pmSTL - BRU

1 stop10h 44mUnited Airlines

Tue 2/1010:00 amBRU - STL

2 stops32h 02mUnited Airlines

Deal found 12/3

$463

Fri 1/3011:29 amMCI - BRU

1 stop14h 26mLufthansa

Fri 2/610:10 amBRU - MCI

1 stop18h 49mLufthansa

Deal found 12/3

$479

Sun 2/86:06 amMCI - BRU

2 stops30h 49mBritish Airways

Sun 2/155:30 pmBRU - MCI

2 stops36h 05mBritish Airways

Deal found 12/3

$483

Fri 1/303:24 pmMCI - BRU

1 stop10h 31mUnited Airlines

Fri 2/610:00 amBRU - MCI

2 stops31h 32mUnited Airlines

Deal found 12/3

$463

Fri 1/3010:00 amMCI - BRU

2 stops14h 50mAir Canada

Fri 2/610:00 amBRU - MCI

2 stops35h 22mAir Canada

Deal found 12/3

$466

Fri 1/3011:29 amMCI - BRU

1 stop14h 26mLufthansa

Tue 2/310:10 amBRU - MCI

1 stop14h 31mLufthansa

Deal found 12/1

$482

Fri 1/303:24 pmMCI - BRU

1 stop10h 31mUnited Airlines

Tue 2/310:00 amBRU - MCI

2 stops35h 27mUnited Airlines

Deal found 12/2

$463

Thu 1/294:05 pmSTL - BRU

2 stops33h 50mAir Canada

Tue 2/310:00 amBRU - STL

2 stops36h 15mAir Canada

Deal found 12/3

$480

Mon 1/126:40 pmSTL - BRU

1 stop31h 15mLufthansa

Mon 1/1911:15 amBRU - STL

1 stop19h 44mLufthansa

Deal found 12/2

$484

Fri 1/169:57 amSTL - BRU

2 stops20h 18mUnited Airlines

Fri 1/2310:10 amBRU - STL

1 stop14h 33mUnited Airlines

Deal found 12/2

$478

Fri 1/238:52 amJLN - BRU

2 stops21h 23mUnited Airlines

Tue 1/2710:00 amBRU - JLN

2 stops38h 34mUnited Airlines

Deal found 12/1

$479

Thu 1/294:05 pmSTL - BRU

2 stops14h 10mUnited Airlines

Tue 2/310:10 amBRU - STL

1 stop14h 33mUnited Airlines

Deal found 12/3

$480

Sun 1/1812:35 pmMCI - BRU

1 stop11h 40mUnited Airlines

Sun 1/2510:10 amBRU - MCI

1 stop18h 49mUnited Airlines

Deal found 12/3

$482

Fri 1/1611:29 amMCI - BRU

2 stops18h 46mUnited Airlines

Fri 1/2310:00 amBRU - MCI

2 stops18h 59mUnited Airlines

Deal found 12/2

$482

Wed 2/189:03 amSGF - BRU

2 stops21h 12mUnited Airlines

Sun 2/2210:10 amBRU - SGF

1 stop18h 49mUnited Airlines

Deal found 12/2

$503

Last-minute flights from Missouri to Bruxelles-National
Discover last-minute flight deals from Missouri to Bruxelles-National. Data last updated December 4, 2025 and is based on user searches.

Mon 1/126:44 pmSTL - BRU

2 stops14h 56mBritish Airways

Mon 1/193:00 pmBRU - STL

2 stops38h 44mBritish Airways

Deal found 12/2

$460

Mon 1/1212:44 pmSTL - BRU

1 stop11h 31mMultiple Airlines

Mon 1/199:50 amBRU - STL

2 stops45h 09mMultiple Airlines

Deal found 12/2

$473

Tue 1/1312:44 pmSTL - BRU

1 stop11h 31mMultiple Airlines

Tue 1/206:30 amBRU - STL

2 stops24h 29mMultiple Airlines

Deal found 12/2

$421

Tue 1/138:05 amSTL - BRU

2 stops16h 45mAir Canada

Tue 1/2010:00 amBRU - STL

2 stops35h 30mAir Canada

Deal found 12/2

$441

Tue 1/1311:22 amSTL - BRU

1 stop13h 43mLufthansa

Tue 1/2011:15 amBRU - STL

1 stop19h 44mLufthansa

Deal found 12/2

$467

Fri 1/169:57 amSTL - BRU

2 stops20h 18mUnited Airlines

Fri 1/2310:10 amBRU - STL

1 stop14h 33mUnited Airlines

Deal found 12/2

$478

Fri 1/1610:00 amMCI - BRU

2 stops20h 15mUnited Airlines

Fri 1/2310:10 amBRU - MCI

1 stop18h 49mUnited Airlines

Deal found 12/2

$478

Fri 1/238:52 amJLN - BRU

2 stops21h 23mUnited Airlines

Tue 1/2710:00 amBRU - JLN

2 stops38h 34mUnited Airlines

Deal found 12/1

$479

Thu 1/294:05 pmSTL - BRU

2 stops14h 10mUnited Airlines

Tue 2/310:10 amBRU - STL

1 stop14h 33mUnited Airlines

Deal found 12/3

$480

Fri 1/303:24 pmMCI - BRU

1 stop10h 31mUnited Airlines

Tue 2/310:00 amBRU - MCI

2 stops35h 27mUnited Airlines

Deal found 12/2

$463

Fri 1/308:00 amMCI - BRU

2 stops16h 50mAir Canada

Tue 2/310:00 amBRU - MCI

2 stops38h 41mAir Canada

Deal found 12/1

$466

Fri 1/3011:29 amMCI - BRU

1 stop14h 26mLufthansa

Fri 2/610:10 amBRU - MCI

1 stop18h 49mLufthansa

Deal found 12/3

$479

One-way flights from Missouri to Bruxelles-National
Search for one-way flight options from Missouri to Bruxelles-National. Find affordable one-way fares based on user searches. Data last updated December 4, 2025.

Sun 1/46:35 pmSTL - BRU

1 stop31h 20mLufthansa

Deal found 12/4

$408

Tue 1/611:20 amSTL - BRU

2 stops18h 55mUnited Airlines

Deal found 12/4

$415

Sun 1/44:05 pmSTL - BRU

2 stops14h 10mAir Canada

Deal found 12/3

$417

Tue 1/66:40 pmSTL - BRU

2 stops30h 10mAir Canada

Deal found 12/3

$423

Fri 1/26:35 pmSTL - BRU

2 stops15h 55mUnited Airlines

Deal found 12/4

$438

Tue 1/65:11 pmSTL - BRU

3 stops34h 49mMultiple Airlines

Deal found 12/4

$459

Sat 1/36:35 pmSTL - BRU

1 stop31h 20mLufthansa

Deal found 12/3

$471

Mon 1/54:05 pmSTL - BRU

2 stops32h 45mAir Canada

Deal found 12/3

$525

Tue 5/125:55 pmMCI - BRU

3 stops40h 35mMultiple Airlines

Deal found 12/4

$1,186

Tue 5/126:08 pmMCI - BRU

2 stops17h 52mIberia

Deal found 12/4

$1,385

Tue 5/1212:06 pmMCI - BRU

1 stop12h 39mLufthansa

Deal found 12/4

$1,599

Find flight deals from Missouri to Bruxelles-National

Round-trip from	$421 (Kiwi.com)
One-way from	$408 (Kiwi.com)
Popular in	December
Cheapest in	February
Average price	$2,205

From Missouri to Brussels Bruxelles-National

Search Deals

One-way flight from Missouri to Brussels Bruxelles-National

Search Deals

Highest demand for flights based on searches. 25% potential increase in price ($350 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 12% potential price decrease ($110 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Tue 1/13

12:44 pm-7:15 am

1 stop11h 31m

Brussels Bruxelles-National

Tue 1/20

6:30 am-11:59 pm

2 stops24h 29m

$421

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Tue 1/13

8:05 am-7:50 am

2 stops16h 45m

Brussels Bruxelles-National

Tue 1/20

10:00 am-2:30 pm

2 stops35h 30m

$441

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Wed 2/4

10:50 am-4:20 pm

2 stops22h 30m

Brussels Bruxelles-National

Wed 2/11

11:50 am-11:12 pm

2 stops18h 22m

$458

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Wed 2/4

9:05 am-7:50 am

2 stops15h 45m

Brussels Bruxelles-National

Wed 2/11

10:10 am-5:41 pm

1 stop14h 31m

$461

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Fri 2/6

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Tue 2/10

10:00 am-2:30 pm

2 stops35h 30m

$461

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Fri 2/6

3:11 pm-8:55 am

1 stop10h 44m

Brussels Bruxelles-National

Tue 2/10

10:00 am-11:02 am

2 stops32h 02m

$463

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Fri 1/30

3:24 pm-8:55 am

1 stop10h 31m

Brussels Bruxelles-National

Fri 2/6

10:00 am-10:32 am

2 stops31h 32m

$463

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Fri 1/30

3:24 pm-8:55 am

1 stop10h 31m

Brussels Bruxelles-National

Tue 2/3

10:00 am-2:27 pm

2 stops35h 27m

$463

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Fri 1/30

10:00 am-7:50 am

2 stops14h 50m

Brussels Bruxelles-National

Fri 2/6

10:00 am-2:22 pm

2 stops35h 22m

$466

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Tue 1/13

11:22 am-8:05 am

1 stop13h 43m

Brussels Bruxelles-National

Tue 1/20

11:15 am-11:59 pm

1 stop19h 44m

$467

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 31 results

Best time to book a flight from Missouri to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels Bruxelles-National Airport

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

Currently, April is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $453). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BRU?

It’s optimal to fly from Missouri to Brussels Bruxelles-National Airport in the afternoon. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from Missouri to Brussels Bruxelles-National Airport?

Related info for your journey

How long is the flight from Missouri to Brussels Bruxelles-National Airport?
Departing from Missouri to Brussels Bruxelles-National Airport will take you 15h 45m. Missouri and Brussels Bruxelles-National Airport are separated by a distance of 4528 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?
The most popular flight routes from Missouri to Brussels Bruxelles-National Airport are Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National and Springfield-Branson - Brussels Bruxelles-National.
Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?
Yes. In addition to deals on Missouri to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Bruxelles-National?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Bruxelles-National.
Can I find deals for business class flights from Missouri to Bruxelles-National?
Yes. Cheapflights offers flight deals from Missouri to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?
Currently, April is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $453). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Mons

Hasselt

Charleroi

Mechelen

Zaventem

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Top 2 airlines flying from Missouri to Bruxelles-National

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$640	Average$1,029	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$829	Average$2,205	FlexibilityNo cancel fee	On-time76%

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$408+ Cheap flights from Missouri to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Bruxelles-National

Cheapest flights from Missouri to Bruxelles-NationalExplore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Find flight deals from Missouri to Bruxelles-National

Keep the following information in mind while searching for Missouri to Bruxelles-National flight deals. Data was last updated December 4, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Brussels Bruxelles-National Airport that are best for you.

Best time to book a flight from Missouri to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels Bruxelles-National Airport

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

What is the cheapest time of day to fly from MO to BRU?

Find hourly flight availability from Missouri to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

How much does it cost to fly round-trip from Missouri to Brussels Bruxelles-National Airport?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Brussels Bruxelles-National Airport?

What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?

Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?

How can I find direct flights from Missouri to Bruxelles-National?

Can I find deals for business class flights from Missouri to Bruxelles-National?

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

Traveling to a place near Brussels Bruxelles-National Airport?

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Alternative routes for Missouri to Bruxelles-National

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Top 2 airlines flying from Missouri to Bruxelles-National

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Cheapest flights from Missouri to Bruxelles-National
Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.