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Bruxelles-National

$341+ Cheap flights from Missouri to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from Missouri to Bruxelles-National

Keep the following information in mind while searching for Missouri to Bruxelles-National flight deals. Data was last updated October 14, 2025.

Round-trip from

$525
(United Airlines)

One-way from

$341
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$873
From Missouri to Brussels Bruxelles-National
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One-way flight from Missouri to Brussels Bruxelles-National
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Highest demand for flights based on searches. 18% potential increase in price ($208 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Bruxelles-National

Cheapest flights from Missouri to Bruxelles-National
Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:45 amJLN - BRU
2 stops22h 30mUnited Airlines
Tue 11/1810:00 amBRU - JLN
2 stops44h 30mUnited Airlines
Deal found 10/13$525
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:15 amSGF - BRU
2 stops24h 00mUnited Airlines
Fri 12/510:00 amBRU - SGF
2 stops43h 13mUnited Airlines
Deal found 10/14$530
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:10 pmSTL - BRU
2 stops17h 05mUnited Airlines
Thu 11/2710:00 amBRU - STL
2 stops35h 24mUnited Airlines
Deal found 10/14$530
This Air Canada deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:05 pmSTL - BRU
2 stops14h 10mAir Canada
Thu 11/2710:00 amBRU - STL
2 stops35h 24mAir Canada
Deal found 10/14$532
This Flighttix deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/98:00 amMCI - BRU
2 stops16h 50mMultiple Airlines
Sun 11/1611:15 amBRU - MCI
1 stop16h 55mMultiple Airlines
Deal found 10/12$534
This Flighttix deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/912:45 pmMCI - BRU
1 stop11h 30mLufthansa
Sun 11/1611:15 amBRU - MCI
1 stop16h 55mLufthansa
Deal found 10/12$538
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:36 amMCI - BRU
2 stops18h 39mUnited Airlines
Sun 11/1611:15 amBRU - MCI
1 stop16h 55mUnited Airlines
Deal found 10/13$546
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:00 amMCI - BRU
2 stops18h 50mAir Canada
Sun 11/1610:00 amBRU - MCI
2 stops53h 56mAir Canada
Deal found 10/12$550
This Flighttix deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:00 amSTL - BRU
1 stop15h 55mLufthansa
Thu 12/410:10 amBRU - STL
1 stop13h 53mLufthansa
Deal found 10/12$555
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:05 amMCI - BRU
2 stops20h 10mUnited Airlines
Fri 1/910:10 amBRU - MCI
2 stops30h 21mUnited Airlines
Deal found 10/12$557
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:40 amMCI - BRU
2 stops22h 35mUnited Airlines
Thu 1/84:55 pmBRU - MCI
2 stops28h 32mUnited Airlines
Deal found 10/12$572
This Flysmarter deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:43 pmMCI - BRU
3 stops31h 12mAir Canada
Sun 11/169:30 amBRU - MCI
2 stops19h 58mAir Canada
Deal found 10/13$575

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Missouri to Brussels Bruxelles-National Airport that are best for you.

Fly from

Missouri

Fly to

Bruxelles-National

Route

Depart

Return

Price

JoplinBrussels

JLN - BRU

JLNBRU

Joplin

Fri 11/14

7:45 am-1:15 pm

2 stops22h 30m

Brussels Bruxelles-National

Tue 11/18

10:00 am-11:30 pm

2 stops44h 30m

$525

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Wed 11/12

1:10 pm-1:15 pm

2 stops17h 05m

Brussels Bruxelles-National

Thu 11/27

10:00 am-3:46 pm

2 stops36h 46m

$530

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Thu 11/27

8:25 am-8:55 am

2 stops41h 30m

Brussels Bruxelles-National

Thu 12/4

10:00 am-2:23 pm

2 stops35h 23m

$530

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Wed 12/10

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Mon 2/9

10:00 am-12:29 pm

2 stops33h 29m

$532

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Wed 12/10

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Mon 2/9

10:00 am-12:29 pm

2 stops33h 29m

$532

St. LouisBrussels

STL - BRU

STLBRU

Lambert-St Louis

Wed 11/12

4:05 pm-1:15 pm

2 stops14h 10m

Brussels Bruxelles-National

Thu 11/27

10:00 am-2:24 pm

2 stops35h 24m

$532

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Sun 11/9

8:00 am-7:50 am

2 stops16h 50m

Brussels Bruxelles-National

Sun 11/16

11:15 am-9:10 pm

1 stop16h 55m

$534

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Mon 11/10

3:25 pm-1:15 pm

2 stops14h 50m

Brussels Bruxelles-National

Sun 11/16

11:55 am-8:56 am

2 stops28h 01m

$546

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Thu 1/8

12:35 pm-1:15 pm

2 stops17h 40m

Brussels Bruxelles-National

Sun 1/11

10:10 am-7:57 pm

1 stop16h 47m

$553

Kansas CityBrussels

MCI - BRU

MCIBRU

Kansas City

Wed 1/7

1:42 pm-1:15 pm

2 stops16h 33m

Brussels Bruxelles-National

Sun 1/11

10:10 am-9:59 pm

1 stop18h 49m

$553

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 23 results
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Best time to book a flight from Missouri to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Brussels Bruxelles-National Airport

What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

Currently, October is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $604). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BRU?

Find hourly flight availability from Missouri to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

It’s optimal to fly from Missouri to Brussels Bruxelles-National Airport in the afternoon. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the evening.

How much does it cost to fly round-trip from Missouri to Brussels Bruxelles-National Airport?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Brussels Bruxelles-National Airport?

    Departing from Missouri to Brussels Bruxelles-National Airport will take you 14h 10m. Missouri and Brussels Bruxelles-National Airport are separated by a distance of 4393 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Brussels Bruxelles-National Airport one-way?

    To fly one-way, consider booking your trip with Lufthansa, which is currently one of the cheapest options available, starting at $431. Air Canada flights start at $439 while deals on United Airlines start at $443 one-way.

  • What are the most popular routes from Missouri to Brussels Bruxelles-National Airport?

    The most popular flight routes from Missouri to Brussels Bruxelles-National Airport are Lambert-St Louis - Brussels Bruxelles-National, Kansas City - Brussels Bruxelles-National and Joplin - Brussels Bruxelles-National.

  • Can I find deals for flights from Missouri to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Missouri to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Bruxelles-National.

  • Can I find deals for business class flights from Missouri to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Missouri to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $604). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Charleroi
Mons
Hasselt
Mechelen
Zaventem

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Alternative routes for Missouri to Bruxelles-National

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Missouri to Bruxelles-National

Discover the top airline that operate flights from Missouri to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$640Average$1,105FlexibilityNo cancel feeOn-time69%

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