$222+ Cheap flights from Missouri to Bruxelles-National (BRU)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from Missouri to Bruxelles-National with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Bruxelles-National
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Cheapest flights from Missouri to Bruxelles-NationalExplore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from Missouri to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:05 pm
STL
- BRU
2 stops14h 10m
Multiple Airlines
Wed 3/117:00 am
BRU
- STL
1 stop13h 55m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$470
This Flighttix deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:55 pm
STL
- BRU
2 stops29h 55m
Air Canada
Wed 3/1110:00 am
BRU
- STL
2 stops34h 42m
Air Canada
Deal found 2/2![Air Canada logo]()
$472
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:30 pm
STL
- BRU
2 stops15h 45m
United Airlines
Tue 3/2410:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/1![United Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:25 am
STL
- BRU
1 stop19h 30m
United Airlines
Wed 3/2510:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$489
This Flighttix deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:15 pm
STL
- BRU
1 stop12h 00m
Lufthansa
Wed 3/1110:10 am
BRU
- STL
1 stop13h 50m
Lufthansa
Deal found 2/2![Lufthansa logo]()
$496
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:54 am
JLN
- BRU
2 stops21h 21m
United Airlines
Sun 3/810:10 am
BRU
- JLN
1 stop13h 33m
United Airlines
Deal found 2/2![United Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:17 am
STL
- BRU
2 stops21h 58m
United Airlines
Sun 3/810:10 am
BRU
- STL
1 stop16h 57m
United Airlines
Deal found 2/1![United Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:05 am
MCI
- BRU
1 stop18h 55m
Delta
Tue 3/2410:00 am
BRU
- MCI
1 stop15h 56m
Delta
Deal found 2/3![Delta logo]()
$509
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:15 pm
STL
- BRU
2 stops15h 00m
United Airlines
Sun 3/811:55 am
BRU
- STL
2 stops15h 12m
United Airlines
Deal found 2/1![United Airlines logo]()
$511
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 am
MCI
- BRU
2 stops25h 35m
British Airways
Mon 5/119:55 pm
BRU
- MCI
2 stops31h 06m
British Airways
Deal found 2/2![British Airways logo]()
$511
This oojo deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:13 pm
STL
- BRU
2 stops20h 42m
British Airways
Sun 3/89:35 pm
BRU
- STL
2 stops29h 36m
British Airways
Deal found 2/1![British Airways logo]()
$512
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:17 am
MCI
- BRU
1 stop19h 43m
United Airlines
Thu 5/710:15 am
BRU
- MCI
1 stop18h 44m
United Airlines
Deal found 2/1![United Airlines logo]()
$520
Best flights from Missouri to Bruxelles-NationalDiscover carefully curated flight deals from Missouri to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from Missouri to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:14 pm
STL
- BRU
2 stops18h 01m
United Airlines
Tue 3/2410:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/1![United Airlines logo]()
$487
This Finnair deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:05 am
MCI
- BRU
2 stops20h 05m
Multiple Airlines
Thu 5/77:05 pm
BRU
- MCI
2 stops34h 45m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$527
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:48 am
MCI
- BRU
1 stop13h 52m
KLM
Mon 5/119:45 am
BRU
- MCI
1 stop18h 02m
KLM
Deal found 2/2![KLM logo]()
$559
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:25 am
STL
- BRU
1 stop19h 30m
United Airlines
Wed 3/2510:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:54 am
JLN
- BRU
2 stops41h 01m
United Airlines
Sun 3/810:10 am
BRU
- JLN
1 stop13h 33m
United Airlines
Deal found 1/31![United Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:15 pm
STL
- BRU
2 stops15h 00m
United Airlines
Sun 3/810:10 am
BRU
- STL
1 stop15h 04m
United Airlines
Deal found 2/1![United Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:17 am
STL
- BRU
2 stops21h 58m
United Airlines
Sun 3/810:10 am
BRU
- STL
1 stop16h 57m
United Airlines
Deal found 2/1![United Airlines logo]()
$507
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:17 am
MCI
- BRU
1 stop19h 43m
United Airlines
Thu 5/710:15 am
BRU
- MCI
1 stop18h 44m
United Airlines
Deal found 2/1![United Airlines logo]()
$520
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:30 am
MCI
- BRU
1 stop14h 30m
United Airlines
Mon 5/119:25 am
BRU
- MCI
2 stops42h 16m
United Airlines
Deal found 2/2![United Airlines logo]()
$539
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:10 am
MCI
- BRU
2 stops21h 05m
United Airlines
Sun 3/110:00 am
BRU
- MCI
2 stops36h 45m
United Airlines
Deal found 1/31![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/273:22 pm
MCI
- BRU
2 stops14h 53m
United Airlines
Fri 3/610:00 am
BRU
- MCI
2 stops35h 26m
United Airlines
Deal found 2/1![United Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:55 am
SGF
- BRU
2 stops22h 20m
United Airlines
Sun 2/2210:10 am
BRU
- SGF
1 stop18h 49m
United Airlines
Deal found 1/31![United Airlines logo]()
$688
Last-minute flights from Missouri to Bruxelles-NationalDiscover last-minute flight deals from Missouri to Bruxelles-National. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Bruxelles-National. Data last updated February 3, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:17 am
STL
- BRU
2 stops21h 58m
United Airlines
Sun 3/810:10 am
BRU
- STL
1 stop16h 57m
United Airlines
Deal found 2/1![United Airlines logo]()
$507
This oojo deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:13 pm
STL
- BRU
2 stops20h 42m
British Airways
Sun 3/89:35 pm
BRU
- STL
2 stops29h 36m
British Airways
Deal found 2/1![British Airways logo]()
$512
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:05 pm
STL
- BRU
2 stops14h 10m
Multiple Airlines
Wed 3/117:00 am
BRU
- STL
1 stop13h 55m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$470
This Flighttix deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:55 pm
STL
- BRU
2 stops29h 55m
Air Canada
Wed 3/1110:00 am
BRU
- STL
2 stops34h 42m
Air Canada
Deal found 2/2![Air Canada logo]()
$472
This Flighttix deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:15 pm
STL
- BRU
1 stop12h 00m
Lufthansa
Wed 3/1110:10 am
BRU
- STL
1 stop13h 50m
Lufthansa
Deal found 2/2![Lufthansa logo]()
$496
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:15 pm
STL
- BRU
2 stops15h 00m
United Airlines
Sun 3/811:55 am
BRU
- STL
2 stops15h 12m
United Airlines
Deal found 2/1![United Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:54 am
JLN
- BRU
2 stops21h 21m
United Airlines
Sun 3/810:10 am
BRU
- JLN
1 stop13h 33m
United Airlines
Deal found 2/2![United Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:30 pm
STL
- BRU
2 stops15h 45m
United Airlines
Tue 3/2410:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/1![United Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:25 am
STL
- BRU
1 stop19h 30m
United Airlines
Wed 3/2510:00 am
BRU
- STL
2 stops38h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$489
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:05 am
MCI
- BRU
1 stop18h 55m
Delta
Tue 3/2410:00 am
BRU
- MCI
1 stop15h 56m
Delta
Deal found 2/3![Delta logo]()
$509
This Ovago deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:05 am
MCI
- BRU
2 stops25h 10m
Brussels Airlines
Tue 3/2410:00 am
BRU
- MCI
2 stops29h 30m
Brussels Airlines
Deal found 2/3![Brussels Airlines logo]()
$560
This Gurufare deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:33 am
MCI
- BRU
2 stops18h 37m
Scandinavian Airlines
Tue 3/2410:00 am
BRU
- MCI
1 stop15h 56m
Scandinavian Airlines
Deal found 2/3![Scandinavian Airlines logo]()
$620
One-way flights from Missouri to Bruxelles-NationalSearch for one-way flight options from Missouri to Bruxelles-National. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from Missouri to Bruxelles-National. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:15 am
MCI
- BRU
2 stops24h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$222
This KLM deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1110:30 am
MCI
- BRU
1 stop14h 10m
KLM
Deal found 2/3![KLM logo]()
$225
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:12 pm
MCI
- BRU
3 stops35h 58m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$333
This FlightHub deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:24 am
MCI
- BRU
2 stops19h 16m
Aer Lingus
Deal found 2/2![Aer Lingus logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
MCI
- BRU
3 stops43h 20m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$347
This Priceline deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:24 am
MCI
- BRU
2 stops43h 16m
Aer Lingus
Deal found 2/2![Aer Lingus logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:13 am
MCI
- BRU
3 stops49h 42m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
STL
- BRU
2 stops23h 55m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
MCI
- BRU
3 stops23h 55m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:15 am
MCI
- BRU
2 stops30h 45m
United Airlines
Deal found 2/2![United Airlines logo]()
$397
This FlightHub deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:00 pm
STL
- BRU
1 stop11h 10m
Air Canada
Deal found 2/3![Air Canada logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/262:15 pm
MCI
- BRU
3 stops36h 10m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$403
Find flight deals from Missouri to Bruxelles-National
Keep the following information in mind while searching for Missouri to Bruxelles-National flight deals. Data was last updated February 3, 2026.
Round-trip from | $470 (Mytrip) |
|---|---|
One-way from | $222 (United Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $512 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Missouri to Brussels Bruxelles-National Airport that are best for you.
Fly from
Missouri
Fly to
Bruxelles-National
Route
Depart
Return
Price
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Tue 3/17
1:14 pm-1:15 pm
2 stops18h 01m
Brussels Bruxelles-National
Tue 3/24
10:00 am-6:00 pm
2 stops38h 00m
$487
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Wed 3/18
6:25 am-7:55 am
1 stop19h 30m
Brussels Bruxelles-National
Wed 3/25
10:00 am-6:00 pm
2 stops38h 00m
$489
JoplinBrussels
JLN - BRU
JLNBRU
Joplin
Wed 3/4
8:54 am-8:55 am
2 stops41h 01m
Brussels Bruxelles-National
Sun 3/8
10:10 am-5:43 pm
1 stop13h 33m
$502
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Tue 3/3
3:15 pm-1:15 pm
2 stops15h 00m
Brussels Bruxelles-National
Sun 3/8
10:10 am-7:14 pm
1 stop15h 04m
$507
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Sun 3/1
8:17 am-1:15 pm
2 stops21h 58m
Brussels Bruxelles-National
Sun 3/8
10:10 am-9:07 pm
1 stop16h 57m
$507
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Sun 5/3
6:17 am-9:00 am
1 stop19h 43m
Brussels Bruxelles-National
Thu 5/7
10:15 am-9:59 pm
1 stop18h 44m
$520
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Sun 5/3
11:05 am-2:10 pm
2 stops20h 05m
Brussels Bruxelles-National
Thu 5/7
7:05 pm-10:50 pm
2 stops34h 45m
$527
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Wed 5/6
11:30 am-9:00 am
1 stop14h 30m
Brussels Bruxelles-National
Mon 5/11
9:25 am-8:41 pm
2 stops42h 16m
$539
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Wed 5/6
10:48 am-7:40 am
1 stop13h 52m
Brussels Bruxelles-National
Mon 5/11
9:45 am-8:47 pm
1 stop18h 02m
$559
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Wed 2/25
9:10 am-1:15 pm
2 stops21h 05m
Brussels Bruxelles-National
Sun 3/1
10:00 am-3:45 pm
2 stops36h 45m
$668
Showing 1-10 of 27 results
Best time to book a flight from Missouri to Bruxelles-National
Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Missouri with our price prediction graph.
STL-BRU
JLN-BRU
MCI-BRU
SGF-BRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Brussels Bruxelles-National Airport
USMO-BRU
STL-BRU
JLN-BRU
MCI-BRU
SGF-BRU
What is the cheapest month to book a flight from Missouri to Brussels Bruxelles-National Airport?
Currently, April is the cheapest month in which you can book a flight from Missouri to Brussels Bruxelles-National Airport (average of $443). Flying from Missouri to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Brussels Bruxelles-National Airport?
Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locationsMons
Hasselt
Charleroi
Mechelen
Zaventem
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Alternative routes for Missouri to Bruxelles-National
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Other flights to Bruxelles-National
Explore flights to Bruxelles-National departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 3, 2026.
Complete your trip
Complete your trip to Bruxelles-National by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Bruxelles-National by cabin class
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Missouri and Bruxelles-National flights
Browse other Missouri and Bruxelles-National flight options. Last updated on February 3, 2026.
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Missouri to Bruxelles-National flights
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Top 2 airlines flying from Missouri to Bruxelles-National
Discover the top 2 airlines that operate flights from Missouri to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$441 | Average$2,205 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$506 | Average$747 | FlexibilityNo cancel fee | On-time69% |