$309+ Cheap flights from Missouri to Brussels
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
Jul 6 — Jul 131
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Brussels
Keep the following information in mind while searching for Missouri to Brussels flight deals. Data was last updated July 1, 2025.
Round-trip from | $628 (United Airlines) |
|---|---|
One-way from | $309 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $1,048 |
Find flight deals from Missouri to Brussels
Cheapest flights from Missouri to BrusselsExplore the most affordable flight options available from Missouri to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.
Explore the most affordable flight options available from Missouri to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:30 amSTL - BRU
2 stops14h 20mUnited Airlines
Thu 11/2710:00 amBRU - STL
2 stops36h 29mUnited Airlines
Deal found 6/30![United Airlines logo]()
$582
This Air Canada deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:05 pmSTL - BRU
2 stops56h 45mAir Canada
Wed 11/2610:00 amBRU - STL
2 stops35h 20mAir Canada
Deal found 6/30![Air Canada logo]()
$584
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:00 amMCI - BRU
2 stops14h 15mUnited Airlines
Fri 1/910:00 amBRU - MCI
2 stops35h 50mUnited Airlines
Deal found 7/1![United Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:00 amJLN - BRU
1 stop16h 55mUnited Airlines
Tue 11/1810:00 amBRU - JLN
2 stops44h 30mUnited Airlines
Deal found 6/29![United Airlines logo]()
$628
This Booking.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/128:00 amMCI - BRU
2 stops17h 00mAir Canada
Sat 8/2310:00 amBRU - MCI
2 stops20h 27mAir Canada
Deal found 7/1![Air Canada logo]()
$646
This Lufthansa deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:50 pmSTL - BRU
1 stop11h 20mLufthansa
Mon 11/242:25 pmBRU - STL
2 stops39h 22mLufthansa
Deal found 6/30![Lufthansa logo]()
$659
This FlightHub deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:30 pmSGF - BRU
2 stops20h 00mScandinavian Airlines
Thu 10/1610:20 amBRU - SGF
2 stops19h 12mScandinavian Airlines
Deal found 6/30![Scandinavian Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:45 amSGF - BRU
1 stop18h 15mUnited Airlines
Thu 10/1610:00 amBRU - SGF
2 stops31h 50mUnited Airlines
Deal found 6/30![United Airlines logo]()
$662
This KLM deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1410:44 amMCI - BRU
1 stop14h 56mMultiple Airlines
Sun 8/2410:45 amBRU - MCI
1 stop18h 41mMultiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$705
This KLM deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1410:44 amMCI - BRU
2 stops13h 46mKLM
Sun 8/2410:45 amBRU - MCI
1 stop13h 52mKLM
Deal found 7/1![KLM logo]()
$750
This Scandinavian Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/171:30 pmSTL - BRU
2 stops18h 00mScandinavian Airlines
Sun 11/303:10 pmBRU - STL
2 stops39h 29mScandinavian Airlines
Deal found 6/30![Scandinavian Airlines logo]()
$783
This Lufthansa deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1711:49 amSTL - BRU
1 stop13h 16mMultiple Airlines
Thu 11/2710:10 amBRU - STL
1 stop12h 19mMultiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$825
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from Missouri to Brussels that are best for you.
Fly from
Missouri
Fly to
Brussels
Route
Depart
Return
Price
JoplinBrussels
JLN - BRU
JLNBRU
Joplin
Fri 11/14
9:00 am-7:50 am
2 stops15h 50m
Brussels Bruxelles-National
Tue 11/18
10:00 am-11:30 pm
2 stops44h 30m
$628
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Tue 8/12
8:00 am-8:00 am
2 stops17h 00m
Brussels Bruxelles-National
Sat 8/23
10:00 am-11:27 pm
2 stops20h 27m
$646
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Tue 8/12
11:31 am-8:00 am
2 stops13h 29m
Brussels Bruxelles-National
Sat 8/23
10:15 am-5:20 pm
1 stop14h 05m
$655
SpringfieldBrussels
SGF - BRU
SGFBRU
Springfield-Branson
Tue 10/7
3:30 pm-6:30 pm
2 stops20h 00m
Brussels Bruxelles-National
Thu 10/16
10:20 am-10:32 pm
2 stops19h 12m
$659
SpringfieldBrussels
SGF - BRU
SGFBRU
Springfield-Branson
Tue 10/7
7:45 am-9:00 am
1 stop18h 15m
Brussels Bruxelles-National
Thu 10/16
10:00 am-10:50 am
2 stops31h 50m
$662
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Thu 8/14
1:30 pm-8:00 am
1 stop11h 30m
Brussels Bruxelles-National
Thu 8/21
10:15 am-3:44 pm
1 stop12h 29m
$701
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Thu 8/14
10:44 am-8:40 am
1 stop14h 56m
Brussels Bruxelles-National
Sun 8/24
10:45 am-10:26 pm
1 stop18h 41m
$705
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Thu 8/14
10:44 am-7:30 am
2 stops13h 46m
Brussels Bruxelles-National
Sun 8/24
10:45 am-5:37 pm
1 stop13h 52m
$750
SpringfieldBrussels
SGF - BRU
SGFBRU
Springfield-Branson
Thu 9/25
6:00 am-8:40 am
1 stop19h 40m
Brussels Bruxelles-National
Mon 9/29
10:45 am-10:02 pm
2 stops18h 17m
$870
Kansas CityBrussels
MCI - BRU
MCIBRU
Kansas City
Sun 7/20
8:10 am-8:40 am
2 stops17h 30m
Brussels Bruxelles-National
Fri 8/1
10:45 am-5:32 pm
1 stop13h 47m
$905
Showing 1-10 of 36 results
Best time to book a flight from Missouri to Brussels
Have a flexible travel schedule? Discover the best time to fly to Brussels from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Brussels
What is the cheapest month to book a flight from Missouri to Brussels?
Currently, November is the cheapest month in which you can book a flight from Missouri to Brussels (average of $614). Flying from Missouri to Brussels in June is currently the most expensive (average of $1,083). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to BRU?
Find hourly flight availability from Missouri to Brussels. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 1, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Brussels as you normally would.
Reviews of airlines servicing Brussels
Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated July 1, 2025.
See what other customers who have flown with Delta, KLM, and Air France from Missouri to Brussels have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.2
Food
7.3
Overall
8.0
Entertainment
7.9
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Food
7.3
Overall
8.0
Entertainment
7.9
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Food
7.3
Overall
8.0
Entertainment
7.9
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Food
7.3
Overall
8.0
Entertainment
7.9
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Food
7.3
Overall
8.0
Entertainment
7.9
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Crew
8.5
Boarding
8.2
Food
7.3
Overall
8.0
Entertainment
7.9
Comfort
7.9
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from Missouri to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Brussels
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from Missouri to Brussels
Discover the top airline that operate flights from Missouri to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$628 | Average$999 | FlexibilityNo cancel fee | On-time69% |