HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Myrtle Beach

$262+ Cheap flights from Sioux Falls to Myrtle Beach (FSD - MYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — MYR
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to Myrtle Beach with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to Myrtle Beach

Cheapest flights from Sioux Falls to Myrtle Beach
Explore the most affordable flight options available from Sioux Falls to Myrtle Beach. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:14 pm
FSD
-
MYR
2 stops9h 42m
American Airlines
Tue 2/2410:26 am
MYR
-
FSD
2 stops9h 44m
American Airlines
Deal found 1/25$262
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:07 pm
FSD
-
MYR
2 stops8h 48m
American Airlines
Tue 3/310:26 am
MYR
-
FSD
2 stops9h 44m
American Airlines
Deal found 1/25$276
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/97:01 pm
FSD
-
MYR
1 stop23h 09m
Multiple Airlines
Fri 2/139:09 am
MYR
-
FSD
1 stop9h 15m
Multiple Airlines
Deal found 1/25$281
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/282:07 pm
FSD
-
MYR
2 stops8h 48m
American Airlines
Thu 3/59:30 am
MYR
-
FSD
2 stops10h 40m
American Airlines
Deal found 1/25$290
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:11 pm
FSD
-
MYR
1 stop22h 28m
Multiple Airlines
Fri 4/179:58 am
MYR
-
FSD
1 stop8h 23m
Multiple Airlines
Deal found 1/25$306
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/245:15 am
FSD
-
MYR
1 stop7h 24m
Delta
Thu 7/303:40 pm
MYR
-
FSD
1 stop7h 29m
Delta
Deal found 1/26$309
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2512:14 pm
FSD
-
MYR
2 stops9h 42m
American Airlines
Wed 3/410:26 am
MYR
-
FSD
2 stops9h 44m
American Airlines
Deal found 1/26$321
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:15 am
FSD
-
MYR
1 stop7h 24m
Delta
Thu 7/303:40 pm
MYR
-
FSD
1 stop7h 29m
Delta
Deal found 1/26$335
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:26 pm
FSD
-
MYR
2 stops7h 28m
American Airlines
Wed 2/1810:26 am
MYR
-
FSD
2 stops9h 44m
American Airlines
Deal found 1/25$396
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:14 pm
FSD
-
MYR
1 stop10h 57m
American Airlines
Wed 3/1112:16 pm
MYR
-
FSD
1 stop7h 54m
American Airlines
Deal found 1/25$464

Find flight deals from Sioux Falls to Myrtle Beach

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Myrtle Beach (MYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$262
(American Airlines)

Popular in

December

Cheapest in

November
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Myrtle Beach Intl flights.
Search Deals
From Sioux Falls Joe Foss Field to Myrtle Beach Intl
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Myrtle Beach that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Sioux Falls to Myrtle Beach that are best for you.

Fly from

Sioux Falls

Fly to

Myrtle Beach

Route

Depart

Return

Price

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 2/18

12:14 pm-10:56 pm

2 stops9h 42m

Myrtle Beach Intl

Tue 2/24

10:26 am-7:10 pm

2 stops9h 44m

$262

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Mon 2/9

7:01 pm-7:10 pm

1 stop23h 09m

Myrtle Beach Intl

Fri 2/13

9:09 am-5:24 pm

1 stop9h 15m

$281

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 2/28

2:07 pm-11:55 pm

2 stops8h 48m

Myrtle Beach Intl

Thu 3/5

9:30 am-7:10 pm

2 stops10h 40m

$290

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Mon 4/13

6:11 pm-5:39 pm

1 stop22h 28m

Myrtle Beach Intl

Fri 4/17

9:58 am-5:21 pm

1 stop8h 23m

$306

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 7/24

5:15 am-1:39 pm

1 stop7h 24m

Myrtle Beach Intl

Thu 7/30

3:40 pm-10:09 pm

1 stop7h 29m

$309

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 2/25

12:14 pm-10:56 pm

2 stops9h 42m

Myrtle Beach Intl

Wed 3/4

10:26 am-7:10 pm

2 stops9h 44m

$321

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Thu 7/23

5:15 am-1:39 pm

1 stop7h 24m

Myrtle Beach Intl

Thu 7/30

3:40 pm-10:09 pm

1 stop7h 29m

$335

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Wed 2/11

12:26 pm-8:54 pm

2 stops7h 28m

Myrtle Beach Intl

Wed 2/18

10:26 am-7:10 pm

2 stops9h 44m

$396

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 3/7

12:14 pm-12:11 am

1 stop10h 57m

Myrtle Beach Intl

Wed 3/11

12:16 pm-7:10 pm

1 stop7h 54m

$464

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Compare providers for flights from Sioux Falls to Myrtle Beach

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Myrtle Beach in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Myrtle Beach flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Myrtle Beach flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Myrtle Beach flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Myrtle Beach flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Myrtle Beach

Have a flexible travel schedule? Discover the best time to fly to Myrtle Beach from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Myrtle Beach

What is the cheapest month to book a flight from Sioux Falls to Myrtle Beach?

Currently, August is the cheapest month in which you can book a flight from Sioux Falls to Myrtle Beach (average of $148). Flying from Sioux Falls to Myrtle Beach in October is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Myrtle Beach

Get insights into the airlines that provide service to Myrtle Beach. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Myrtle Beach. Reviews last updated January 26, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Myrtle Beach. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,199 reviews
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,111 reviews

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.8

Crew

8.5

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Myrtle Beach. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Sioux Falls to Myrtle Beach?

    Departing from Sioux Falls to Myrtle Beach will take you 9h 42m. The distance between Sioux Falls and Myrtle Beach is about 1175 mi.

  • What are the cheapest airlines flying from Sioux Falls to Myrtle Beach round-trip?

    Flying on Delta is currently your cheapest option to Myrtle Beach, with prices starting at $258. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $261 and $273, respectively. Delta is currently priced 33% below the average price you’ll pay for this route.

  • Can I find deals for flights from Sioux Falls to Myrtle Beach that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Myrtle Beach flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Myrtle Beach?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Myrtle Beach.

  • Can I find deals for business class flights from Sioux Falls to Myrtle Beach?

    Yes. Cheapflights offers flight deals from Sioux Falls to Myrtle Beach by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Myrtle Beach?

    Currently, August is the cheapest month in which you can book a flight from Sioux Falls to Myrtle Beach (average of $148). Flying from Sioux Falls to Myrtle Beach in October is currently the most expensive (average of $330). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
Conway
Surfside Beach
Little River
Pawleys Island
Ocean Isle Beach
Garden City Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Sioux Falls to Myrtle Beach

Discover the top 3 airlines that operate flights from Sioux Falls to Myrtle Beach. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$258Average$473FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$261Average$360FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$273Average$372FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.