$631+ Cheap flights from Southend (SEN) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
SEN — STL
Mar 24 — Mar 311
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Southend to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Southend to Missouri
One-way
One-way flights from Southend to MissouriSearch for one-way flight options from Southend to Missouri. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
Search for one-way flight options from Southend to Missouri. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:05 pm
SEN
- STL
3 stops59h 54m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$631
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:10 am
SEN
- STL
3 stops35h 41m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$641
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:25 am
SEN
- STL
3 stops40h 28m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$682
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2010:00 am
SEN
- STL
3 stops28h 46m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$779
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 pm
SEN
- STL
3 stops45h 16m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$1,101
Find flight deals from Southend to Missouri
Keep the following information in mind while searching for Southend to Missouri flight deals. Data was last updated February 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Popular in | July |
Cheapest in | March |
Average price | $873 |
Cheapflights Fare Finder
Customize your flight search to find flights from Southend to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from London Southend Airport to Missouri that are best for you.
Fly from
Southend
Fly to
Missouri
Route
Depart
Return
Price
LondonSt. Louis
SEN - STL
SENSTL
London Southend
Thu 2/26
6:05 pm-11:59 pm
3 stops59h 54m
$631
LondonSt. Louis
SEN - STL
SENSTL
London Southend
Wed 3/11
7:10 am-1:51 pm
3 stops35h 41m
$641
LondonSt. Louis
SEN - STL
SENSTL
London Southend
Sun 3/29
7:25 am-5:53 pm
3 stops40h 28m
$682
LondonSt. Louis
SEN - STL
SENSTL
London Southend
Wed 7/8
6:00 pm-9:16 am
3 stops45h 16m
$1,101
Best time to book a flight from Southend to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Southend with our price prediction graph.
SEN-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from London Southend Airport to Missouri
SEN-USMO
SEN-STL
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Southend to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights