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$298+ Cheap flights from Santo Domingo (SDQ) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — STL
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Santo Domingo to Missouri

Keep the following information in mind while searching for Santo Domingo to Missouri flight deals. Data was last updated July 31, 2025.

Round-trip from

$334
(SmartFares)

One-way from

$298
(Delta)

Popular in

May

Cheapest in

July

Average price

$486
From Santo Domingo Las Americas to Missouri
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One-way flight from Santo Domingo Las Americas to Missouri
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Highest demand for flights based on searches. 10% potential increase in price ($67 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santo Domingo to Missouri

Cheapest flights from Santo Domingo to Missouri
Explore the most affordable flight options available from Santo Domingo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This SmartFares deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:20 pmSDQ - MCI
1 stop10h 47mSpirit Airlines
Sun 9/145:15 amMCI - SDQ
1 stop6h 00mSpirit Airlines
Deal found 7/29$334
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/23:35 pmSDQ - MCI
3 stops32h 32mMultiple Airlines
Tue 10/75:15 amMCI - SDQ
3 stops32h 41mMultiple Airlines
Deal found 7/29$494
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:56 pmSDQ - MCI
1 stop8h 31mDelta
Mon 10/275:56 amMCI - SDQ
1 stop6h 45mDelta
Deal found 7/30$572
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:45 amSDQ - MCI
2 stops17h 00mUnited Airlines
Mon 10/278:00 amMCI - SDQ
2 stops13h 46mUnited Airlines
Deal found 7/28$582
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/24:20 pmSDQ - MCI
1 stop8h 58mAmerican Airlines
Thu 8/145:17 amMCI - SDQ
2 stops14h 13mAmerican Airlines
Deal found 7/29$655

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Santo Domingo to Missouri that are best for you.

Fly from

Santo Domingo

Fly to

Missouri

Route

Depart

Return

Price

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 9/4

1:20 pm-11:07 pm

1 stop10h 47m

Kansas City

Sun 9/14

5:15 am-12:15 pm

1 stop6h 00m

$334

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 10/2

3:35 pm-11:07 pm

3 stops32h 32m

Kansas City

Tue 10/7

5:15 am-2:56 pm

3 stops32h 41m

$494

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 10/23

2:56 pm-10:27 pm

1 stop8h 31m

Kansas City

Mon 10/27

5:56 am-1:41 pm

1 stop6h 45m

$572

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 10/23

5:45 am-9:45 pm

2 stops17h 00m

Kansas City

Mon 10/27

8:00 am-10:46 pm

2 stops13h 46m

$582

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Wed 10/1

2:50 pm-11:44 pm

1 stop9h 54m

$298

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 8/7

7:05 am-5:36 pm

2 stops11h 31m

$307

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 8/7

4:52 pm-5:09 pm

1 stop25h 17m

$338

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Thu 8/7

5:39 pm-3:17 pm

3 stops46h 38m

$464

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Santo Domingo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Missouri

What is the cheapest month to book a flight from Santo Domingo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Santo Domingo to Missouri (average of $311). Flying from Santo Domingo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to MO?

Find hourly flight availability from Santo Domingo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Santo Domingo to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Santo Domingo to Missouri, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.
Spirit Airlines
6.3
Okay
8,049 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
8.0
Excellent

Michael,Jul 2025

AMS - ATL

Overall it was great experience, with the exception of snack food. The food offered in two main meals was just fine but for the mid-flight snack, the only option was a large cookie, too sweet and high sugar content. Snacks at the back of the plane were also mainly sweets. There was one nice baked cheddar option but it quickly ran out.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Missouri?

    Located just 17.5 mi from the city center, Santo Domingo Las Americas (SDQ) is the airport most travelers will use when flying to Missouri from Santo Domingo.

  • What are the cheapest airlines to fly from Santo Domingo to Missouri one-way?

    The cheapest airlines for a one-way flight from Santo Domingo to Missouri are Delta ($298), American Airlines ($307), and Spirit Airlines ($338).

  • Can I find deals for flights from Santo Domingo to Missouri that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Missouri.

  • Can I find deals for business class flights from Santo Domingo to Missouri?

    Yes. Cheapflights offers flight deals from Santo Domingo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Santo Domingo to Missouri (average of $311). Flying from Santo Domingo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Punta Cana to O'Hare Intl flights
Punta Cana to Fort Lauderdale flights
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Santiago de los Caballeros to Fort Lauderdale flights
Santo Domingo to Raleigh flights
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Punta Cana to Dulles Intl flights
Punta Cana to Atlanta flights
Santo Domingo to Charlotte flights
Santo Domingo to Midway flights
Santo Domingo to Tampa flights
Punta Cana to Baltimore flights
Santo Domingo to Denver flights
Santiago de los Caballeros to Las Vegas flights
Santo Domingo to Columbus flights
Santiago de los Caballeros to Charlotte flights
Santo Domingo to Hobby flights
Punta Cana to Hobby flights
Santo Domingo to Cleveland flights

Top 2 airlines flying from Santo Domingo to Missouri

Discover the top 2 airlines that operate flights from Santo Domingo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$341Average$566FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$463Average$616FlexibilityNo cancel feeOn-time71%

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