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$191+ Cheap flights from Santo Domingo (SDQ) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — STL
Feb 17 — Feb 241
Tue 2/17
Tue 2/24
1 adult, Economy
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Cheap flight deals from Santo Domingo to Missouri

Keep the following information in mind while searching for Santo Domingo to Missouri flight deals. Data was last updated January 18, 2026.

Round-trip from

$348
(Cheapflightsfares)

One-way from

$191
(Cheapflightsfares)
From Santo Domingo Las Americas to Missouri
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One-way flight from Santo Domingo Las Americas to Missouri
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Find flight deals from Santo Domingo to Missouri

Cheapest flights from Santo Domingo to Missouri
Explore the most affordable flight options available from Santo Domingo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 18, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:59 am
SDQ
-
MCI
1 stop8h 24m
Spirit Airlines
Sat 4/411:26 am
MCI
-
SDQ
1 stop13h 12m
Spirit Airlines
Deal found 1/16$348
This Cheapflightsfares deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:59 am
SDQ
-
MCI
1 stop8h 24m
Spirit Airlines
Fri 4/311:26 am
MCI
-
SDQ
1 stop13h 12m
Spirit Airlines
Deal found 1/16$395
This Mytrip deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:59 am
SDQ
-
MCI
1 stop8h 24m
Spirit Airlines
Thu 4/911:26 am
MCI
-
SDQ
1 stop13h 12m
Spirit Airlines
Deal found 1/16$426

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 18, 2026.
Use the filters below to find and compare flights from Santo Domingo to Missouri that are best for you.

Fly from

Santo Domingo

Fly to

Missouri

Route

Depart

Return

Price

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Tue 3/24

2:59 am-10:23 am

1 stop8h 24m

Kansas City

Sat 4/4

11:26 am-1:38 am

1 stop13h 12m

$348

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Tue 3/24

2:59 am-10:23 am

1 stop8h 24m

Kansas City

Fri 4/3

11:26 am-1:38 am

1 stop13h 12m

$395

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Tue 3/31

2:59 am-10:23 am

1 stop8h 24m

Kansas City

Thu 4/9

11:26 am-1:38 am

1 stop13h 12m

$426

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Tue 3/24

2:59 am-10:23 am

1 stop8h 24m

$191

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Fri 5/29

3:37 pm-11:07 am

1 stop20h 30m

$217

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Tue 5/5

3:37 pm-11:59 pm

2 stops33h 22m

$273

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Sat 5/30

6:10 am-11:59 pm

2 stops18h 49m

$278

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Wed 3/25

10:19 am-7:55 pm

3 stops34h 36m

$279

Santo DomingoKansas City

SDQ - MCI

SDQMCI

Santo Domingo Las Americas

Tue 4/28

3:35 pm-11:07 am

3 stops44h 32m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/18

Best time to book a flight from Santo Domingo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Missouri

What is the cheapest month to book a flight from Santo Domingo to Missouri?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Missouri (average of $256). Flying from Santo Domingo to Missouri in August is currently the most expensive (average of $672). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santo Domingo to Missouri?

    Located just 17.5 mi from the city center, Santo Domingo Las Americas (SDQ) is the airport most travelers will use when flying to Missouri from Santo Domingo.

  • How long is the flight from Santo Domingo to Missouri?

    There are many flights that can get you from Santo Domingo to Missouri in 8h 24m. Fly via Spirit Airlines to get the fastest option. Airlines will cover a distance of 2077 mi.

  • Can I find deals for flights from Santo Domingo to Missouri that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Missouri.

  • Can I find deals for business class flights from Santo Domingo to Missouri?

    Yes. Cheapflights offers flight deals from Santo Domingo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Missouri?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Missouri (average of $256). Flying from Santo Domingo to Missouri in August is currently the most expensive (average of $672). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santo Domingo to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Santo Domingo to George Bush Intcntl flights
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Santo Domingo to Raleigh flights

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