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$676+ Cheap flights from Prague (PRG) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/29. Fares are subject to change and may not be available on all flights or dates of travel.
PRG — STL
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Prague to Missouri

Keep the following information in mind while searching for Prague to Missouri flight deals. Data was last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$849
(Mytrip)

One-way from

$676
(American Airlines)
Provider with most accurate pricing for Václav Havel Prague-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Václav Havel Prague-Lambert-St Louis flights.
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From Václav Havel Prague to Missouri
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One-way flight from Václav Havel Prague to Missouri
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Find flight deals from Prague to Missouri

Cheapest flights from Prague to Missouri
Explore the most affordable flight options available from Prague to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/122:50 pmPRG - MCI
3 stops28h 38mMultiple Airlines
Sat 11/156:00 amMCI - PRG
3 stops24h 55mMultiple Airlines
Deal found 10/21$849
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amPRG - STL
2 stops17h 43mDelta
Mon 11/106:09 pmSTL - PRG
2 stops15h 56mDelta
Deal found 10/22$899
This Gotogate deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:30 amPRG - STL
1 stop13h 25mLufthansa
Sun 11/93:50 pmSTL - PRG
1 stop15h 25mLufthansa
Deal found 10/21$907
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amPRG - MCI
2 stops17h 53mDelta
Sun 11/99:59 amMCI - PRG
2 stops18h 41mDelta
Deal found 10/21$908
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amPRG - STL
2 stops17h 43mDelta
Sun 11/911:39 amSTL - PRG
2 stops13h 46mDelta
Deal found 10/21$911
This Lufthansa deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:45 pmPRG - STL
1 stop26h 10mLufthansa
Mon 11/106:43 pmSTL - PRG
2 stops14h 22mLufthansa
Deal found 10/22$935
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amPRG - SGF
2 stops18h 04mAmerican Airlines
Tue 11/116:20 pmSGF - PRG
2 stops21h 30mAmerican Airlines
Deal found 10/22$936
This Expedia deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:15 amPRG - STL
2 stops17h 48mLufthansa
Sat 12/136:42 pmSTL - PRG
2 stops35h 23mLufthansa
Deal found 10/22$953
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:45 amPRG - MCI
2 stops24h 40mAmerican Airlines
Mon 12/83:39 pmMCI - PRG
2 stops21h 56mAmerican Airlines
Deal found 10/22$960
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:30 pmPRG - MCI
2 stops16h 17mDelta
Mon 12/88:05 amMCI - PRG
2 stops20h 35mDelta
Deal found 10/21$1,008
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:10 pmPRG - MCI
2 stops33h 11mUnited Airlines
Fri 12/123:25 pmMCI - PRG
2 stops24h 00mUnited Airlines
Deal found 10/21$1,017
This Mytrip deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:50 pmPRG - MCI
3 stops34h 38mMultiple Airlines
Mon 11/106:00 amMCI - PRG
3 stops20h 35mMultiple Airlines
Deal found 10/21$1,154

Cheapflights Fare Finder

 
Customize your flight search to find flights from Prague to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Prague to Missouri that are best for you.

Fly from

Prague

Fly to

Missouri

Route

Depart

Return

Price

PragueKansas City

PRG - MCI

PRGMCI

Václav Havel Prague

Wed 11/12

2:50 pm-12:28 pm

3 stops28h 38m

Kansas City

Sat 11/15

6:00 am-1:55 pm

3 stops24h 55m

$849

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Thu 11/6

6:00 am-4:43 pm

2 stops17h 43m

Lambert-St Louis

Mon 11/10

6:09 pm-5:05 pm

2 stops15h 56m

$899

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 11/5

7:30 am-1:55 pm

1 stop13h 25m

Lambert-St Louis

Sun 11/9

3:50 pm-2:15 pm

1 stop15h 25m

$907

PragueKansas City

PRG - MCI

PRGMCI

Václav Havel Prague

Thu 11/6

6:00 am-4:53 pm

2 stops17h 53m

Kansas City

Mon 11/10

5:47 pm-5:05 pm

2 stops16h 18m

$908

PragueKansas City

PRG - MCI

PRGMCI

Václav Havel Prague

Wed 11/5

6:00 am-4:53 pm

2 stops17h 53m

Kansas City

Sun 11/9

9:59 am-11:40 am

2 stops18h 41m

$908

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 11/5

6:00 am-4:43 pm

2 stops17h 43m

Lambert-St Louis

Sun 11/9

11:39 am-8:25 am

2 stops13h 46m

$911

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Wed 3/18

7:30 am-2:55 pm

1 stop13h 25m

Lambert-St Louis

Tue 4/14

5:18 pm-4:00 pm

2 stops15h 42m

$918

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Thu 11/6

6:45 pm-1:55 pm

1 stop26h 10m

Lambert-St Louis

Mon 11/10

6:43 pm-4:05 pm

2 stops14h 22m

$935

PragueSpringfield

PRG - SGF

PRGSGF

Václav Havel Prague

Fri 11/7

6:00 am-9:09 pm

2 stops22h 09m

Springfield-Branson

Tue 11/11

6:20 pm-10:50 pm

2 stops21h 30m

$936

PragueSt. Louis

PRG - STL

PRGSTL

Václav Havel Prague

Sat 12/6

6:15 am-5:03 pm

2 stops17h 48m

Lambert-St Louis

Sat 12/13

6:42 pm-1:05 pm

2 stops35h 23m

$953

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 23 results
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Best time to book a flight from Prague to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Prague with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Prague to Missouri
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Prague to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Prague to Missouri?

    Most people fly from Václav Havel Prague (PRG) if they book a flight from Prague to Missouri. Václav Havel Prague is conveniently located just 6.9 mi from Prague’s city center.

  • How long is the flight from Prague to Missouri?

    Departing from Prague to Missouri will take you 13h 25m. The distance from Prague to Missouri is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Prague to Missouri?

    When deciding which route to take from Prague to Missouri consider Václav Havel Prague - Kansas City, Václav Havel Prague - Lambert-St Louis or Václav Havel Prague - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Prague to Missouri that include hotel bookings?

    Yes. In addition to deals on Prague to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Prague to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Prague to Missouri.

  • Can I find deals for business class flights from Prague to Missouri?

    Yes. Cheapflights offers flight deals from Prague to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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