HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$401+ Cheap flights from Bruxelles-National (BRU) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — STL
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Bruxelles-National to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Bruxelles-National to Missouri

Keep the following information in mind while searching for Bruxelles-National to Missouri flight deals. Data was last updated October 23, 2025.

Round-trip from

$614
(Flysmarter)

One-way from

$401
(British Airways)

Popular in

April

Cheapest in

June

Average price

$689
From Brussels Bruxelles-National to Missouri
Search Deals
One-way flight from Brussels Bruxelles-National to Missouri
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Bruxelles-National to Missouri

Cheapest flights from Bruxelles-National to Missouri
Explore the most affordable flight options available from Bruxelles-National to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Flysmarter deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/239:35 pmBRU - STL
2 stops25h 52mBritish Airways
Tue 12/22:52 pmSTL - BRU
2 stops12h 58mBritish Airways
Deal found 10/22$614
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:50 amBRU - STL
2 stops15h 34mAmerican Airlines
Sun 12/711:50 amSTL - BRU
2 stops16h 00mAmerican Airlines
Deal found 10/21$620
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:20 amBRU - STL
2 stops19h 36mAmerican Airlines
Tue 12/22:52 pmSTL - BRU
2 stops12h 58mAmerican Airlines
Deal found 10/21$622
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:10 amBRU - STL
1 stop18h 30mLufthansa
Tue 11/1112:31 pmSTL - BRU
1 stop13h 24mLufthansa
Deal found 10/22$652
This Flysmarter deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:00 amBRU - STL
1 stop13h 55mLufthansa
Tue 12/26:42 pmSTL - BRU
2 stops14h 33mLufthansa
Deal found 10/22$655
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:00 amBRU - STL
2 stops16h 00mUnited Airlines
Sun 12/76:42 pmSTL - BRU
1 stop31h 13mUnited Airlines
Deal found 10/22$662
This Flighttix deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2210:00 amBRU - MCI
2 stops20h 42mAir Canada
Wed 11/269:58 amMCI - BRU
2 stops14h 52mAir Canada
Deal found 10/23$711
This Flighttix deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2210:00 amBRU - MCI
2 stops20h 42mMultiple Airlines
Wed 11/2611:36 amMCI - BRU
1 stop14h 19mMultiple Airlines
Deal found 10/23$714
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/811:00 amBRU - MCI
2 stops17h 03mDelta
Mon 11/1710:37 amMCI - BRU
2 stops15h 23mDelta
Deal found 10/22$720
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:00 amBRU - MCI
2 stops17h 54mUnited Airlines
Mon 11/1712:45 pmMCI - BRU
1 stop11h 30mUnited Airlines
Deal found 10/22$721
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:30 amBRU - MCI
2 stops19h 00mUnited Airlines
Fri 12/123:25 pmMCI - BRU
1 stop10h 30mUnited Airlines
Deal found 10/21$828
This Air Canada deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:00 amBRU - MCI
3 stops21h 50mMultiple Airlines
Mon 11/176:05 amMCI - BRU
2 stops18h 45mMultiple Airlines
Deal found 10/22$832

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Missouri that are best for you.

Fly from

Bruxelles-National

Fly to

Missouri

Route

Depart

Return

Price

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Sun 11/23

9:35 pm-4:27 pm

2 stops25h 52m

Lambert-St Louis

Tue 12/2

2:52 pm-10:50 am

2 stops12h 58m

$614

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Wed 12/3

11:50 am-8:24 pm

2 stops15h 34m

Lambert-St Louis

Sun 12/7

11:50 am-10:50 am

2 stops16h 00m

$620

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Sun 11/23

11:20 am-11:56 pm

2 stops19h 36m

Lambert-St Louis

Tue 12/2

2:52 pm-10:50 am

2 stops12h 58m

$622

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Fri 11/7

10:10 am-9:40 pm

1 stop18h 30m

Lambert-St Louis

Tue 11/11

12:31 pm-8:55 am

1 stop13h 24m

$652

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Fri 11/7

9:00 am-9:40 pm

2 stops19h 40m

Lambert-St Louis

Tue 11/11

10:00 am-7:50 am

2 stops14h 50m

$652

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Sun 11/23

7:00 am-1:55 pm

1 stop13h 55m

Lambert-St Louis

Tue 12/2

6:42 pm-4:15 pm

2 stops14h 33m

$655

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Sun 11/23

7:00 am-1:55 pm

1 stop13h 55m

Lambert-St Louis

Tue 12/2

8:30 am-7:15 am

1 stop15h 45m

$659

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Wed 12/3

9:00 am-6:00 pm

2 stops16h 00m

Lambert-St Louis

Sun 12/7

6:42 pm-8:55 am

1 stop31h 13m

$662

BrusselsKansas City

BRU - MCI

BRUMCI

Brussels Bruxelles-National

Sat 11/22

10:00 am-11:42 pm

2 stops20h 42m

Kansas City

Wed 11/26

11:36 am-8:55 am

1 stop14h 19m

$714

BrusselsKansas City

BRU - MCI

BRUMCI

Brussels Bruxelles-National

Sat 11/8

11:00 am-9:03 pm

2 stops17h 03m

Kansas City

Mon 11/17

10:15 am-9:00 am

1 stop15h 45m

$720

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/21

Showing 1-10 of 17 results
1
2

Best time to book a flight from Bruxelles-National to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Brussels Bruxelles-National Airport to Missouri

What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Missouri?

Currently, May is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Missouri (average of $349). Flying from Brussels Bruxelles-National Airport to Missouri in February is currently the most expensive (average of $792). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Brussels Bruxelles-National Airport to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 23, 2025.
Read reviews from past customers who have flown United Airlines, American Airlines, and British Airways from Brussels Bruxelles-National Airport to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,991 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
United Airlines
7.4
Good
8,991 reviews
United Airlines
7.4
Good
8,991 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
American Airlines
7.2
Good
11,028 reviews
United Airlines
7.4
Good
8,991 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.
British Airways
6.7
Okay
7,467 reviews
United Airlines
7.4
Good
8,991 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Crew

8.1

Boarding

7.7

Reviews

1 / 20
8.0
Excellent

Anonymous,Oct 2025

YUL - ORD

Crew and customer service are 5 stars. I had a lot of luggage for a very long trip and they were nothing but helpful and found solutions to every problem. It was my first time flying with United, and they really are the friendly skies. Leg room however, on 2/3 flights was terrible. Same for entertainment: There was only a seat-mounted screen on 1/3 flights. It would have been nice to have on the longest leg of the journey.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Brussels Bruxelles-National Airport to Missouri?

    For as low as $620, British Airways can have you in Missouri from Brussels Bruxelles-National Airport in 15h 34m. Brussels Bruxelles-National Airport and Missouri are separated by a distance of 4393 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Bruxelles-National to Missouri that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Missouri.

  • Can I find deals for business class flights from Bruxelles-National to Missouri?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Missouri?

    Currently, May is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Missouri (average of $349). Flying from Brussels Bruxelles-National Airport to Missouri in February is currently the most expensive (average of $792). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Bruxelles-National to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Bruxelles-National to Newark flights
Bruxelles-National to John F Kennedy Intl flights
Bruxelles-National to LaGuardia flights
Charleroi Brussels to John F Kennedy Intl flights
Bruxelles-National to Miami flights
Bruxelles-National to Dulles Intl flights
Bruxelles-National to Los Angeles flights
Bruxelles-National to Fort Lauderdale flights
Bruxelles-National to O'Hare Intl flights
Charleroi Brussels to Miami flights
Bruxelles-National to West Palm Beach flights
Bruxelles-National to Las Vegas flights
Bruxelles-National to Hobby flights
Bruxelles-National to Baltimore flights
Bruxelles-National to Orlando flights
Bruxelles-National to Reagan-National flights
Bruxelles-National to Seattle flights
Bruxelles-National to San Francisco flights
Bruxelles-National to Dallas/Fort Worth flights
Charleroi Brussels to Los Angeles flights
Bruxelles-National to Atlanta flights
Bruxelles-National to George Bush Intcntl flights
Bruxelles-National to Boston flights
Bruxelles-National to Ontario flights
Bruxelles-National to Midway flights
Charleroi Brussels to San Francisco flights
Bruxelles-National to Santa Ana flights
Charleroi Brussels to Boston flights
Charleroi Brussels to Dulles Intl flights
Bruxelles-National to Honolulu flights
Charleroi Brussels to Orlando flights
Bruxelles-National to Charlotte flights
Bruxelles-National to Sky Harbor Intl flights
Bruxelles-National to Tampa flights
Bruxelles-National to New Orleans flights
Bruxelles-National to Minneapolis flights
Bruxelles-National to Austin flights
Bruxelles-National to Raleigh flights
Charleroi Brussels to Atlanta flights
Bruxelles-National to Detroit flights
Bruxelles-National to Burbank flights
Bruxelles-National to Denver flights
Bruxelles-National to Indianapolis flights
Bruxelles-National to Philadelphia flights
Bruxelles-National to San Diego flights

Top 3 airlines flying from Bruxelles-National to Missouri

Discover the top 3 airlines that operate flights from Bruxelles-National to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$536Average$732FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$560Average$855FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$580Average$589FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.