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$585+ Cheap flights from Bruxelles-National (BRU) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
BRU — STL
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Bruxelles-National to Missouri

Keep the following information in mind while searching for Bruxelles-National to Missouri flight deals. Data was last updated September 17, 2025.

Round-trip from

$585
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$585
From Brussels Bruxelles-National to Missouri
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Bruxelles-National to Missouri

Cheapest flights from Bruxelles-National to Missouri
Explore the most affordable flight options available from Bruxelles-National to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/610:15 amBRU - STL
2 stops20h 41mAmerican Airlines
Sat 11/1510:44 amSTL - BRU
2 stops16h 46mAmerican Airlines
Deal found 9/16$585
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:45 amBRU - STL
2 stops33h 05mAmerican Airlines
Tue 11/42:50 pmSTL - BRU
2 stops13h 00mAmerican Airlines
Deal found 9/17$589
This British Airways deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:35 amBRU - STL
2 stops16h 33mBritish Airways
Sat 11/82:08 pmSTL - BRU
2 stops16h 32mBritish Airways
Deal found 9/17$591
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:35 pmBRU - STL
2 stops27h 47mBritish Airways
Thu 11/66:45 pmSTL - BRU
2 stops15h 15mBritish Airways
Deal found 9/15$631
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:50 amBRU - MCI
2 stops16h 23mAmerican Airlines
Mon 11/176:08 pmMCI - BRU
2 stops15h 32mAmerican Airlines
Deal found 9/15$636
This Finnair deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:25 pmBRU - MCI
2 stops30h 53mMultiple Airlines
Mon 11/171:45 pmMCI - BRU
2 stops19h 55mMultiple Airlines
Deal found 9/15$639
This Lufthansa deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:00 amBRU - STL
1 stop13h 55mLufthansa
Wed 11/1211:49 amSTL - BRU
1 stop13h 16mLufthansa
Deal found 9/16$640
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:50 amBRU - STL
2 stops20h 03mAmerican Airlines
Sat 10/42:01 pmSTL - BRU
2 stops17h 44mAmerican Airlines
Deal found 9/16$643
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:00 amBRU - STL
2 stops18h 54mUnited Airlines
Thu 11/68:25 amSTL - BRU
1 stop15h 50mUnited Airlines
Deal found 9/15$645
This Lufthansa deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:00 amBRU - STL
1 stop13h 55mLufthansa
Sun 12/76:42 pmSTL - BRU
1 stop31h 13mLufthansa
Deal found 9/15$646
This Lufthansa deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:00 amBRU - STL
1 stop13h 55mLufthansa
Tue 11/41:10 pmSTL - BRU
2 stops14h 10mLufthansa
Deal found 9/17$649
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:30 amBRU - STL
2 stops15h 09mUnited Airlines
Sat 11/811:05 amSTL - BRU
2 stops14h 00mUnited Airlines
Deal found 9/17$650

Cheapflights Fare Finder

 
Customize your flight search to find flights from Bruxelles-National to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Brussels Bruxelles-National Airport to Missouri that are best for you.

Fly from

Bruxelles-National

Fly to

Missouri

Route

Depart

Return

Price

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Fri 11/7

11:45 am-11:56 pm

2 stops19h 11m

Lambert-St Louis

Thu 11/13

2:50 pm-10:50 am

2 stops13h 00m

$585

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Fri 11/7

11:45 am-11:56 pm

2 stops19h 11m

Lambert-St Louis

Wed 11/12

3:38 pm-4:20 pm

2 stops17h 42m

$585

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Thu 11/6

10:15 am-11:56 pm

2 stops20h 41m

Lambert-St Louis

Sat 11/15

10:44 am-10:30 am

2 stops16h 46m

$585

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Wed 12/3

11:50 am-8:11 am

2 stops27h 21m

Lambert-St Louis

Sun 12/7

6:00 am-10:50 am

2 stops21h 50m

$585

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Thu 11/6

10:15 am-7:27 pm

2 stops16h 12m

Lambert-St Louis

Wed 11/12

5:40 pm-7:35 pm

2 stops18h 55m

$585

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Thu 11/6

10:15 am-7:27 pm

2 stops16h 12m

Lambert-St Louis

Tue 11/11

2:51 pm-10:50 am

2 stops12h 59m

$585

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Fri 10/31

11:45 am-2:50 pm

2 stops33h 05m

Lambert-St Louis

Tue 11/4

2:50 pm-10:50 am

2 stops13h 00m

$589

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Sat 11/1

11:35 am-10:08 pm

2 stops16h 33m

Lambert-St Louis

Sat 11/8

2:08 pm-1:40 pm

2 stops16h 32m

$591

BrusselsSt. Louis

BRU - STL

BRUSTL

Brussels Bruxelles-National

Thu 10/30

8:35 pm-6:22 pm

2 stops27h 47m

Lambert-St Louis

Thu 11/6

6:45 pm-5:00 pm

2 stops15h 15m

$631

BrusselsKansas City

BRU - MCI

BRUMCI

Brussels Bruxelles-National

Sat 11/8

2:55 pm-5:46 pm

2 stops33h 51m

Kansas City

Mon 11/17

4:16 pm-1:55 pm

2 stops14h 39m

$637

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 19 results
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Best time to book a flight from Bruxelles-National to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Bruxelles-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Brussels Bruxelles-National Airport to Missouri

What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Missouri?

Currently, August is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Missouri (average of $311). Flying from Brussels Bruxelles-National Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown United Airlines, American Airlines, and British Airways from Brussels Bruxelles-National Airport to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
British Airways
6.7
Okay
7,367 reviews
United Airlines
7.4
Good
8,926 reviews

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Comfort

7.3

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from Bruxelles-National to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Brussels Bruxelles-National Airport to Missouri?

    For as low as $668, American Airlines can have you in Missouri from Brussels Bruxelles-National Airport in 17h 59m. Brussels Bruxelles-National Airport and Missouri are separated by a distance of 4528 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Bruxelles-National to Missouri that include hotel bookings?

    Yes. In addition to deals on Bruxelles-National to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Bruxelles-National to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Bruxelles-National to Missouri.

  • Can I find deals for business class flights from Bruxelles-National to Missouri?

    Yes. Cheapflights offers flight deals from Bruxelles-National to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Brussels Bruxelles-National Airport to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Brussels Bruxelles-National Airport to Missouri (average of $311). Flying from Brussels Bruxelles-National Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Bruxelles-National to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Charleroi Brussels to John F Kennedy Intl flights
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Charleroi Brussels to San Francisco flights
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Charleroi Brussels to Atlanta flights
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Charleroi Brussels to Orlando flights
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Charleroi Brussels to Dulles Intl flights
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Top 3 airlines flying from Bruxelles-National to Missouri

Discover the top 3 airlines that operate flights from Bruxelles-National to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
British AirwaysCheapest$536Average$732FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$560Average$855FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$580Average$589FlexibilityNo cancel feeOn-time71%

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