$220+ Cheap flights from Mexico City (MEX) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — STL
Mar 24 — Mar 311
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mexico City to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mexico City to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mexico City to MissouriExplore the most affordable flight options available from Mexico City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
Explore the most affordable flight options available from Mexico City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:40 am
MEX
- STL
1 stop9h 32m
Frontier
Mon 5/183:02 pm
STL
- MEX
1 stop8h 43m
Frontier
Deal found 2/20![Frontier logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:10 am
MEX
- STL
1 stop25h 39m
Multiple Airlines
Mon 3/92:09 pm
STL
- MEX
2 stops33h 21m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:40 am
MEX
- MCI
1 stop28h 26m
Multiple Airlines
Tue 4/285:15 am
MCI
- MEX
1 stop15h 30m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$412
This Frontier deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:55 pm
MEX
- MCI
2 stops17h 11m
Frontier
Mon 4/2711:13 am
MCI
- MEX
2 stops11h 47m
Frontier
Deal found 2/21![Frontier logo]()
$417
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:40 am
MEX
- MCI
1 stop27h 50m
Multiple Airlines
Sat 5/92:51 pm
MCI
- MEX
2 stops32h 54m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$419
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:00 am
MEX
- MCI
2 stops13h 29m
Frontier
Mon 3/210:55 am
MCI
- MEX
2 stops11h 05m
Frontier
Deal found 2/18![Frontier logo]()
$421
This eDestinos deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:10 am
MEX
- STL
1 stop13h 17m
Multiple Airlines
Mon 3/210:11 pm
STL
- MEX
1 stop22h 59m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:40 am
MEX
- MCI
1 stop10h 18m
Multiple Airlines
Tue 4/285:15 am
MCI
- MEX
1 stop15h 30m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$445
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:05 am
MEX
- STL
1 stop11h 20m
Frontier
Mon 4/134:59 pm
STL
- MEX
2 stops18h 46m
Frontier
Deal found 2/20![Frontier logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:40 am
MEX
- MCI
1 stop28h 26m
Multiple Airlines
Mon 4/2711:13 am
MCI
- MEX
2 stops11h 47m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$454
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:55 am
MEX
- STL
2 stops20h 53m
Multiple Airlines
Tue 4/144:59 pm
STL
- MEX
1 stop27h 46m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$456
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:40 am
MEX
- MCI
1 stop10h 18m
Multiple Airlines
Mon 4/135:45 am
MCI
- MEX
2 stops18h 00m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$468
Best flights from Mexico City to MissouriDiscover carefully curated flight deals from Mexico City to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
Discover carefully curated flight deals from Mexico City to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:40 am
MEX
- STL
1 stop9h 32m
Frontier
Mon 5/183:02 pm
STL
- MEX
2 stops20h 43m
Frontier
Deal found 2/18![Frontier logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:10 am
MEX
- STL
1 stop25h 39m
Multiple Airlines
Mon 3/92:09 pm
STL
- MEX
2 stops33h 21m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$411
This eDestinos deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:40 am
MEX
- STL
1 stop9h 32m
Volaris
Mon 5/183:02 pm
STL
- MEX
1 stop8h 43m
Volaris
Deal found 2/19![Volaris logo]()
$473
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:35 am
MEX
- MCI
1 stop6h 09m
United Airlines
Sun 4/126:30 am
MCI
- MEX
1 stop27h 05m
United Airlines
Deal found 2/18![United Airlines logo]()
$483
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/109:00 am
MEX
- MCI
1 stop8h 15m
Delta
Mon 7/139:59 am
MCI
- MEX
1 stop6h 31m
Delta
Deal found 2/20![Delta logo]()
$555
This eDestinos deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:10 am
MEX
- STL
1 stop13h 17m
Multiple Airlines
Mon 3/210:11 pm
STL
- MEX
1 stop22h 59m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$435
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:05 am
MEX
- STL
1 stop11h 20m
Frontier
Mon 4/136:15 am
STL
- MEX
1 stop11h 25m
Frontier
Deal found 2/20![Frontier logo]()
$497
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:55 am
MEX
- STL
2 stops20h 53m
Multiple Airlines
Tue 4/144:59 pm
STL
- MEX
1 stop27h 46m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$456
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:35 am
MEX
- MCI
1 stop9h 32m
United Airlines
Sun 8/167:55 pm
MCI
- MEX
1 stop17h 50m
United Airlines
Deal found 2/18![United Airlines logo]()
$537
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/211:10 am
MEX
- STL
1 stop12h 49m
Frontier
Fri 3/138:24 am
STL
- MEX
1 stop12h 21m
Frontier
Deal found 2/18![Frontier logo]()
$498
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:05 am
MEX
- MCI
1 stop8h 17m
Delta
Sun 8/1610:35 am
MCI
- MEX
1 stop11h 40m
Delta
Deal found 2/19![Delta logo]()
$559
This eDestinos deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:40 am
MEX
- STL
1 stop9h 32m
Multiple Airlines
Mon 5/183:02 pm
STL
- MEX
2 stops27h 28m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$476
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:05 am
MEX
- STL
1 stop11h 52m
Frontier
Sun 5/2411:32 am
STL
- MEX
1 stop9h 13m
Frontier
Deal found 2/18![Frontier logo]()
$500
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:40 am
MEX
- MCI
2 stops10h 32m
United Airlines
Sat 5/98:00 am
MCI
- MEX
2 stops8h 40m
United Airlines
Deal found 2/18![United Airlines logo]()
$551
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:20 pm
MEX
- MCI
3 stops35h 10m
Multiple Airlines
Tue 3/107:00 am
MCI
- MEX
2 stops16h 30m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$504
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
MEX
- MCI
1 stop11h 45m
Multiple Airlines
Mon 3/911:26 am
MCI
- MEX
2 stops36h 04m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$533
This OneTravel deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:40 am
MEX
- MCI
1 stop9h 50m
Frontier
Mon 7/68:21 pm
MCI
- MEX
1 stop22h 09m
Frontier
Deal found 2/18![Frontier logo]()
$605
Last-minute flights from Mexico City to MissouriDiscover last-minute flight deals from Mexico City to Missouri. Data last updated February 22, 2026 and is based on user searches.
Discover last-minute flight deals from Mexico City to Missouri. Data last updated February 22, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:00 am
MEX
- MCI
2 stops13h 29m
Frontier
Mon 3/210:55 am
MCI
- MEX
2 stops11h 05m
Frontier
Deal found 2/18![Frontier logo]()
$421
This eDestinos deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:10 am
MEX
- STL
1 stop13h 17m
Multiple Airlines
Mon 3/210:11 pm
STL
- MEX
1 stop22h 59m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$435
This eDestinos deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:10 am
MEX
- STL
1 stop13h 17m
Volaris
Mon 3/26:00 am
STL
- MEX
1 stop17h 40m
Volaris
Deal found 2/20![Volaris logo]()
$512
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/211:10 am
MEX
- STL
1 stop12h 49m
Frontier
Fri 3/138:24 am
STL
- MEX
1 stop12h 21m
Frontier
Deal found 2/18![Frontier logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/58:10 am
MEX
- STL
1 stop25h 39m
Multiple Airlines
Mon 3/92:09 pm
STL
- MEX
2 stops33h 21m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:50 pm
MEX
- MCI
2 stops21h 05m
Multiple Airlines
Tue 3/107:00 am
MCI
- MEX
1 stop15h 10m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$480
This eDestinos deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
MEX
- MCI
1 stop11h 45m
Multiple Airlines
Mon 3/95:16 pm
MCI
- MEX
2 stops17h 09m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$493
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:05 am
MEX
- MCI
1 stop13h 51m
Delta
Thu 3/267:08 am
MCI
- MEX
1 stop13h 47m
Delta
Deal found 2/19![Delta logo]()
$483
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:25 am
MEX
- MCI
1 stop21h 05m
United Airlines
Sun 3/226:15 am
MCI
- MEX
1 stop27h 50m
United Airlines
Deal found 2/20![United Airlines logo]()
$502
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/293:55 pm
MEX
- STL
2 stops16h 54m
Frontier
Tue 4/76:15 am
STL
- MEX
1 stop11h 25m
Frontier
Deal found 2/20![Frontier logo]()
$527
One-way flights from Mexico City to MissouriSearch for one-way flight options from Mexico City to Missouri. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
Search for one-way flight options from Mexico City to Missouri. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
This eDestinos deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
MEX
- MCI
1 stop11h 45m
Volaris
Deal found 2/20![Volaris logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:40 am
MEX
- STL
2 stops26h 57m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$236
This Trip.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/148:10 am
MEX
- MCI
1 stop10h 45m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$237
This Trip.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:45 pm
MEX
- STL
1 stop17h 34m
Volaris
Deal found 2/19![Volaris logo]()
$245
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:00 am
MEX
- MCI
2 stops15h 53m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:45 pm
MEX
- MCI
2 stops18h 13m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:20 pm
MEX
- MCI
2 stops35h 10m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:50 am
MEX
- STL
2 stops13h 46m
Delta
Deal found 2/19![Delta logo]()
$379
Find flight deals from Mexico City to Missouri
Keep the following information in mind while searching for Mexico City to Missouri flight deals. Data was last updated February 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $376 (Frontier) |
One-way from | $220 (eDestinos) |
Popular in | November |
Cheapest in | September |
Average price | $673 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mexico City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Mexico City to Missouri that are best for you.
Fly from
Mexico City
Fly to
Missouri
Route
Depart
Return
Price
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Sat 5/16
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Mon 5/18
3:02 pm-10:45 am
2 stops20h 43m
$388
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Thu 3/5
8:10 am-9:49 am
1 stop25h 39m
Lambert-St Louis
Mon 3/9
2:09 pm-10:30 pm
2 stops33h 21m
$411
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Fri 2/27
11:10 am-12:27 am
1 stop13h 17m
Lambert-St Louis
Mon 3/2
10:11 pm-9:10 pm
1 stop22h 59m
$435
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Tue 4/7
11:55 am-9:48 am
2 stops20h 53m
Lambert-St Louis
Tue 4/14
4:59 pm-7:45 pm
1 stop27h 46m
$456
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Sat 5/16
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Mon 5/18
3:02 pm-10:45 pm
1 stop8h 43m
$473
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Sat 5/16
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Mon 5/18
3:02 pm-5:30 pm
2 stops27h 28m
$476
Mexico CityKansas City
MEX - MCI
MEXMCI
Mexico City Benito Juarez
Wed 4/8
9:35 am-4:44 pm
1 stop6h 09m
Kansas City
Sun 4/12
6:30 am-8:35 am
1 stop27h 05m
$483
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Mon 4/6
11:05 am-11:25 pm
1 stop11h 20m
Lambert-St Louis
Mon 4/13
6:15 am-4:40 pm
1 stop11h 25m
$497
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Mon 3/2
11:10 am-11:59 pm
1 stop12h 49m
Lambert-St Louis
Fri 3/13
8:24 am-7:45 pm
1 stop12h 21m
$498
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Thu 5/21
11:05 am-11:57 pm
1 stop11h 52m
Lambert-St Louis
Sun 5/24
11:32 am-7:45 pm
1 stop9h 13m
$500
Showing 1-10 of 29 results
Best time to book a flight from Mexico City to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Mexico City with our price prediction graph.
MEX-STL
MEX-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mexico City to Missouri
MEX-USMO
MEX-STL
MEX-MCI
What is the cheapest month to book a flight from Mexico City to Missouri?
Currently, October is the cheapest month in which you can book a flight from Mexico City to Missouri (average of $334). Flying from Mexico City to Missouri in June is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mexico City to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 22, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Mexico City to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Mexico City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Mexico City to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mexico City to Missouri by cabin class
Find flights from Mexico City to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mexico City and Missouri flights
Browse other Mexico City and Missouri flight options. Last updated on February 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mexico City to Missouri flights
Consider these flights traveling from Mexico City to Missouri.
Top 3 airlines flying from Mexico City to Missouri
Discover the top 3 airlines that operate flights from Mexico City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$466 | Average$591 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$500 | Average$667 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$533 | Average$672 | FlexibilityNo cancel fee | On-time71% |